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Progress in antitumor activity of baicalin
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Bang-yan KONG, li-bin WEI, Qing-long GUO*
Acta Pharmaceutica Sinica | 2021, 56(6) : 1537 - 1543
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Acta Pharmaceutica Sinica | 2021, 56(6): 1537-1543
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Progress in antitumor activity of baicalin
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Bang-yan KONG, li-bin WEI, Qing-long GUO*
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  • School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China
Published: 2021-06-12 doi: 10.16438/j.0513-4870.2020-1642
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Flavonoids baicalin is the main bioactive component extracted from Scutellaria baicalensis Georgi. Baicalin has high medicinal value and shows extensive pharmacological effects including antitumor, antibiosis, anti-inflammatory, antioxidation, neuro-protection, and significant potential in tumor treatment. Recent studies have shown that baicalin suppresses the growth of many kinds of human cancer. The underlying mechanisms include induction of apoptosis, induction of cell cycle arrest, inhibition of tumor metastasis, suppression of angiogenesis, and so on. This article reviewed the research progress of baicalin on its antitumor pharmacology and possible mechanisms at home and abroad, and provided the basis for its further research.

baicalin  /  tumor therapy  /  cell cycle  /  apoptosis  /  invasion and metastasis
Bang-yan KONG, li-bin WEI, Qing-long GUO. Progress in antitumor activity of baicalin[J]. Acta Pharmaceutica Sinica, 2021 , 56 (6) : 1537 -1543 . DOI: 10.16438/j.0513-4870.2020-1642
Year 2021 volume 56 Issue 6
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Article Info
doi: 10.16438/j.0513-4870.2020-1642
  • Receive Date:2020-10-20
  • Online Date:2025-12-18
  • Published:2021-06-12
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  • Received:2020-10-20
  • Revised:2020-12-30
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    School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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