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Chemical constituents of triterpenoid saponins from Glycyrrhiza glabra
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Yun-feng ZHENG1, 2, Jie SUN1, Wei-ping DUAN1, Yang LI1, Li-hong CHEN1, Tu-lin LU1, Cun-yu LI1, 2, Guo-ping PENG*, 1, 2
Acta Pharmaceutica Sinica | 2021, 56(1) : 289 - 295
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Acta Pharmaceutica Sinica | 2021, 56(1): 289-295
• Original Articles •
Chemical constituents of triterpenoid saponins from Glycyrrhiza glabra
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Yun-feng ZHENG1, 2, Jie SUN1, Wei-ping DUAN1, Yang LI1, Li-hong CHEN1, Tu-lin LU1, Cun-yu LI1, 2, Guo-ping PENG*, 1, 2
Affiliations
  • 1. School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
  • 2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China
Published: 2021-01-12 doi: 10.16438/j.0513-4870.2020-1406
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Ten triterpenoid saponins were isolated and purified from the water extract of Glycyrrhiza glabra by polyamide resin combined with macroporous resin column chromatography, ODS medium pressure column chromatography and semi-preparative RP-HPLC. Their structures were elucidated by physicochemical properties, NMR and MS spectra, and determined as 3β-O-[β-D-glucuronpyranosyl-(1→2)-β-D-glucuronpyranosyl]-30β-O-β-D-glucuronpyranosyl-oleanane-11-oxo-12(13)-ene(1), 3β-O-[β-D-glucuronpyranosyl-(1→2)-β-D-glucuronpyranosyl]-30 β-O-α-L-rhamnopyranosyl-oleanane-11-oxo-12(13)-en-22 β, 30-diol(2), uralsaponin C(3), licorice-saponin A3(4), licorice-saponin P2(5), 22β-acetoxyl-glycyrrhizin(6), macedonoside A(7), 29-hydroxyl-glycyrrhizin(8), licorice-saponin G2(9), glycyrrhizin(10). Compounds 1 and 2 are two new compounds and named as licorice-saponin R3 and licorice-saponin S3.

Glycyrrhiza glabra L.  /  chemical composition  /  triterpenoid saponin
Yun-feng ZHENG, Jie SUN, Wei-ping DUAN, Yang LI, Li-hong CHEN, Tu-lin LU, Cun-yu LI, Guo-ping PENG. Chemical constituents of triterpenoid saponins from Glycyrrhiza glabra[J]. Acta Pharmaceutica Sinica, 2021 , 56 (1) : 289 -295 . DOI: 10.16438/j.0513-4870.2020-1406
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Article Info
doi: 10.16438/j.0513-4870.2020-1406
  • Receive Date：2020-08-26
  • Online Date：2025-12-18
  • Published：2021-01-12
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History
  • Received：2020-08-26
  • Revised：2020-09-08
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    1. School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
    2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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