Home Journals Articles Updates About
CN
image
收藏切换
Research progress on the regulation of tumor metabolism, tumor immunotherapy and new analytical methods
收藏切换
PDF
Xiang-yi WANG1, Jin ZHANG1, Yan LI2, *, Jiu-ming HE1, *
Acta Pharmaceutica Sinica | 2020, 55(9) : 2080 - 2091
Less
收藏切换
Acta Pharmaceutica Sinica | 2020, 55(9): 2080-2091
• Reviews •
Research progress on the regulation of tumor metabolism, tumor immunotherapy and new analytical methods
Full
Xiang-yi WANG1, Jin ZHANG1, Yan LI2, *, Jiu-ming HE1, *
Affiliations
  • 1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • 2. Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2020-09-12 doi: 10.16438/j.0513-4870.2020-1025
Outline
收藏切换

In order to achieve rapid proliferation and adapt to the complex microenvironment, tumor cells have dominant characteristics such as unique metabolic patterns and the ability to escape from immunoregulation. Tumor cells reprogram multiple metabolic pathways to promote immune escape, which impacts tumor diagnosis, treatment and prognosis. Based on the effect of metabolic changes on tumor immune escape and its molecular mechanism, metabolic regulation provides new approaches to enhance immunotherapy. We review recent advances in tumor immuno-escape and immunotherapy based on metabolic regulation. Cutting-edge analytical techniques and methods for tumor metabolism research such as metabolomics, mass spectrometry imaging-based spatially-resolved metabolomics and metabolic flow analysis are also discussed.

tumor metabolism  /  tumor immune escape  /  immunotherapy  /  metabolomics  /  mass spectrometry imaging  /  metabolic flux
Xiang-yi WANG, Jin ZHANG, Yan LI, Jiu-ming HE. Research progress on the regulation of tumor metabolism, tumor immunotherapy and new analytical methods[J]. Acta Pharmaceutica Sinica, 2020 , 55 (9) : 2080 -2091 . DOI: 10.16438/j.0513-4870.2020-1025
Appendix
Less
Year 2020 volume 55 Issue 9
PDF
131
55
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2020-1025
  • Receive Date：2020-06-18
  • Online Date：2026-01-23
  • Published：2020-09-12
Article Data
Affiliations
History
  • Received：2020-06-18
  • Revised：2020-07-28
Funding
Affiliations
    1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    2. Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2020-1025
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House