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Recent advances of metal-organic frameworks applied in biomedicine
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Huai-song WANG, Ya DING*
Acta Pharmaceutica Sinica | 2020, 55(7) : 1511 - 1519
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Acta Pharmaceutica Sinica | 2020, 55(7): 1511-1519
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Recent advances of metal-organic frameworks applied in biomedicine
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Huai-song WANG, Ya DING*
Affiliations
  • Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China
Published: 2020-07-12 doi: 10.16438/j.0513-4870.2020-0881
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Metal-organic frameworks (MOFs) are porous crystalline polymers constructed from the coordination reaction between organic ligands and metal ions. Due to their advantages:adjustable periodic pore structure, large specific surface area and easy functional modification, etc., MOFs have been widely used in the fields of gas storage/separation, catalysis, sensing, biological imaging and drug delivery. In recent years, MOFs have shown great potential in disease diagnosis and treatment. This review summarizes the application of MOFs in the fields of bio-sensing, cell imaging, in vivo imaging, drug delivery, etc., discusses the problems and corresponding solutions in the application of MOFs for biomedicine. We hope this review can provide reference for the designing new methods for disease diagnosis and treatment.

metal-organic framework  /  bio-sensing  /  bio-imaging  /  disease diagnosis  /  disease treatment
Huai-song WANG, Ya DING. Recent advances of metal-organic frameworks applied in biomedicine[J]. Acta Pharmaceutica Sinica, 2020 , 55 (7) : 1511 -1519 . DOI: 10.16438/j.0513-4870.2020-0881
Year 2020 volume 55 Issue 7
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doi: 10.16438/j.0513-4870.2020-0881
  • Receive Date:2020-06-01
  • Online Date:2026-01-21
  • Published:2020-07-12
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  • Received:2020-06-01
  • Revised:2020-06-20
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    Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
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占总种数比例
Percentage of
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种数
Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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