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Research progress on ion channels and receptors in nodose ganglion neurons involved in blood pressure regulation
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Li-fang HUO1, Zhan-feng JIA2, Wei ZHANG1, *
Acta Pharmaceutica Sinica | 2020, 55(7) : 1364 - 1372
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Acta Pharmaceutica Sinica | 2020, 55(7): 1364-1372
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Research progress on ion channels and receptors in nodose ganglion neurons involved in blood pressure regulation
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Li-fang HUO1, Zhan-feng JIA2, Wei ZHANG1, *
Affiliations
  • 1. Institute of Chinese Integrative Medicine, Hebei Medical University, Shijiazhuang 050017, China
  • 2. The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Medical University, Shijiazhuang 050017, China
Published: 2020-07-12 doi: 10.16438/j.0513-4870.2020-0877
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Hypertension is the most common cardiovascular disease. In recent years, reduced baroreceptor activity has been suggested as a main cause of hypertension. The cell body of the primary afferent nerve of the baroreceptor is located in the nodose ganglion (NG). The ion channels and receptors in the NG can affect baroreceptor sensitivity and neuronal excitability, thus regulating blood pressure. This review focuses on recent research progress on ion channels, receptors and other proteins in NG neurons that are involved in modulating the sensitivity of the baroreceptor reflex to regulate blood pressure.

nodose ganglion  /  ion channel  /  receptor  /  baroreflex  /  hypertension
Li-fang HUO, Zhan-feng JIA, Wei ZHANG. Research progress on ion channels and receptors in nodose ganglion neurons involved in blood pressure regulation[J]. Acta Pharmaceutica Sinica, 2020 , 55 (7) : 1364 -1372 . DOI: 10.16438/j.0513-4870.2020-0877
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Article Info
doi: 10.16438/j.0513-4870.2020-0877
  • Receive Date：2020-05-30
  • Online Date：2026-01-21
  • Published：2020-07-12
Article Data
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History
  • Received：2020-05-30
  • Accepted：2020-06-19
Funding
Affiliations
    1. Institute of Chinese Integrative Medicine, Hebei Medical University, Shijiazhuang 050017, China
    2. The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Medical University, Shijiazhuang 050017, China
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