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Research advances on the chemical constituents and pharmacological effects of snow lotus
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Lu-ming YANG1, Hu-biao CHEN2, Qiao-ru GUO1, Bolati Makabili3, Wen-min ZHOU1, Pei-min HUANG1, Zeng-bao WU4, Jian-ye ZHANG1, *
Acta Pharmaceutica Sinica | 2020, 55(7) : 1466 - 1477
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Acta Pharmaceutica Sinica | 2020, 55(7): 1466-1477
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Research advances on the chemical constituents and pharmacological effects of snow lotus
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Lu-ming YANG1, Hu-biao CHEN2, Qiao-ru GUO1, Bolati Makabili3, Wen-min ZHOU1, Pei-min HUANG1, Zeng-bao WU4, Jian-ye ZHANG1, *
Affiliations
  • 1. Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China
  • 2. School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
  • 3. Xinjiang Institute of Materia Medica, Urumqi 830004, China
  • 4. Key Laboratory of Xinjiang Phytomedicine Resources of Ministry of Education, School of Pharmacy, Shihezi University, Shihezi 832000, China
Published: 2020-07-12 doi: 10.16438/j.0513-4870.2020-0445
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Snow lotus is a medicinal plant with a wide range of pharmacological activities. It has been used to treat rheumatoid arthritis, cough with cold, stomach ache, dysmenorrhea, and altitude sickness in traditional medicine. This review summarizes the bioactive components in six species of snow lotus including flavonoids, lignans, phenolic compounds, phenylpropanoids, and sesquiterpenes present in Saussurea involucrate (SI), Saussurea obvallata (SO), Saussurea laniceps (SL), Saussurea medusa (SM), Saussurea stella (SS) and Saussurea tridactyla (ST). We review the pharmacological and related molecular mechanisms by which these components exert antineoplastic, anti-inflammatory, and antioxidant effects and promote lipid catabolism, and provide a reference for the future study of the traditional Chinese medicinal chemistry and pharmacological activities of snow lotus.

snow lotus  /  flavonoid  /  lignan  /  anti-tumor  /  anti-inflammation
Lu-ming YANG, Hu-biao CHEN, Qiao-ru GUO, Bolati Makabili, Wen-min ZHOU, Pei-min HUANG, Zeng-bao WU, Jian-ye ZHANG. Research advances on the chemical constituents and pharmacological effects of snow lotus[J]. Acta Pharmaceutica Sinica, 2020 , 55 (7) : 1466 -1477 . DOI: 10.16438/j.0513-4870.2020-0445
Year 2020 volume 55 Issue 7
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Article Info
doi: 10.16438/j.0513-4870.2020-0445
  • Receive Date:2020-03-31
  • Online Date:2026-01-21
  • Published:2020-07-12
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  • Received:2020-03-31
  • Accepted:2020-05-09
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Affiliations
    1. Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China
    2. School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
    3. Xinjiang Institute of Materia Medica, Urumqi 830004, China
    4. Key Laboratory of Xinjiang Phytomedicine Resources of Ministry of Education, School of Pharmacy, Shihezi University, Shihezi 832000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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