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Research progress of reactive nitrogen species on cell protection and injury
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Su-juan CHEN1, Chen-chen PANG1, Bin LIU1, *, Chao-shen HUANGFU2, *
Acta Pharmaceutica Sinica | 2020, 55(12) : 2785 - 2792
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Acta Pharmaceutica Sinica | 2020, 55(12): 2785-2792
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Research progress of reactive nitrogen species on cell protection and injury
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Su-juan CHEN1, Chen-chen PANG1, Bin LIU1, *, Chao-shen HUANGFU2, *
Affiliations
  • 1. School of Nursing and Health, Henan University, Kaifeng 475004, China
  • 2. Institute of Environmental Medicine, Henan University, Kaifeng 475004, China
Published: 2020-12-12 doi: 10.16438/j.0513-4870.2020-0431
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Reactive nitrogen species (RNS) affects intracellular redox balance and induces post-translational modification of proteins. Moreover, RNS, as the signal molecule, participates in the transduction of cellular signals under physiological conditions. However, excessive RNS can induce nitrosative stress and then damage cells, and thereby may play a role in the tumor initiation and progression. Thus, we discussed the role of RNS under physiological conditions and the tumor microenvironment, which may provide some novel ideas for the development of new drugs and the treatment of diseases.

reactive nitrogen species  /  nitrosative protein modification  /  NO3--NO2--NO pathway  /  tumor growth  /  tumor treatment
Su-juan CHEN, Chen-chen PANG, Bin LIU, Chao-shen HUANGFU. Research progress of reactive nitrogen species on cell protection and injury[J]. Acta Pharmaceutica Sinica, 2020 , 55 (12) : 2785 -2792 . DOI: 10.16438/j.0513-4870.2020-0431
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Article Info
doi: 10.16438/j.0513-4870.2020-0431
  • Receive Date：2020-03-30
  • Online Date：2026-01-23
  • Published：2020-12-12
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  • Received：2020-03-30
  • Revised：2020-05-22
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Affiliations
    1. School of Nursing and Health, Henan University, Kaifeng 475004, China
    2. Institute of Environmental Medicine, Henan University, Kaifeng 475004, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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