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Research progress on therapeutic drugs for corona virus disease 2019
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Lu YANG1, 2, Hui-qiang WANG1, 2, Yu-huan LI1, 2
Acta Pharmaceutica Sinica | 2020, 55(6) : 1081 - 1090
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Acta Pharmaceutica Sinica | 2020, 55(6): 1081-1090
• Anti Novel Coronavirus Drugs Researchs •
Research progress on therapeutic drugs for corona virus disease 2019
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Lu YANG1, 2, Hui-qiang WANG1, 2, Yu-huan LI1, 2
Affiliations
  • 1. Key Laboratory of Antiviral Drugs, Chinese Academy of Medical Sciences, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • 2. Beijing Key Laboratory of Anti-Infective Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2020-06-12 doi: 10.16438/j.0513-4870.2020-0324
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Corona virus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. At present, there is no specific antiviral drug for this virus, and the main clinical treatment is support and symptomatic treatment. Direct targeting the virus and the host targets are two strategies for the development of antiviral drugs. At present, the research and development of COVID-19 therapeutic drugs has made some progress on both approaches. Here we review potential anti-SARS-CoV-2 drugs to discuss the antiviral mechanisms and potential of these drugs from the perspectives of virus and host. The role of traditional Chinese medicine in the treatment of COVID-19 is discussed along with the prospects for drug treatment strategies of COVID-19.

severe acute respiratory syndrome coronavirus 2  /  corona virus disease 2019  /  antiviral drug  /  mechanism
Lu YANG, Hui-qiang WANG, Yu-huan LI. Research progress on therapeutic drugs for corona virus disease 2019[J]. Acta Pharmaceutica Sinica, 2020 , 55 (6) : 1081 -1090 . DOI: 10.16438/j.0513-4870.2020-0324
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Article Info
doi: 10.16438/j.0513-4870.2020-0324
  • Receive Date：2020-03-13
  • Online Date：2026-01-21
  • Published：2020-06-12
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  • Received：2020-03-13
  • Revised：2020-04-07
Funding
Affiliations
    1. Key Laboratory of Antiviral Drugs, Chinese Academy of Medical Sciences, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    2. Beijing Key Laboratory of Anti-Infective Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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