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Advances and prospects of pharmacological activities of Dendrobium officinale Kimura et Migo polysaccharides
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Le SUN, Xiao-mei CHEN, Chong-ming WU*, Shun-xing GUO*
Acta Pharmaceutica Sinica | 2020, 55(10) : 2322 - 2329
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Acta Pharmaceutica Sinica | 2020, 55(10): 2322-2329
• Reviews •
Advances and prospects of pharmacological activities of Dendrobium officinale Kimura et Migo polysaccharides
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Le SUN, Xiao-mei CHEN, Chong-ming WU*, Shun-xing GUO*
Affiliations
  • Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100193, China
Published: 2020-10-12 doi: 10.16438/j.0513-4870.2020-0126
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Dendrobium officinale Kimura et Migo (D. officinale) has been used as a valuable traditional Chinese medicine for more than 2 000 years in China. Modern research has confirmed a wide range of pharmacological activities, such as regulating blood sugar, improving gastrointestinal inflammation, and regulating immunity. Polysaccharides are the main active ingredients of D.officinale. With the intensive studies of the pharmacological activities of D.officinale, evidence for the pharmacological effects and potential mechanisms of D.officinale polysaccharides has increased dramatically. In this review, we summarized the latest progress in the pharmacological and mechanical studies of D.officinale polysaccharides, and based on the pharmacological efficacy and oral absorption and utilization characteristics of D.officinale polysaccharides, it is proposed that regulating the gut microbiota may be one of the key mechanisms for D.officinale to exert its beneficial effects. Research on the mechanism of D.officinale polysaccharides puts forward new research directions and prospects.

Dendrobium officinale Kimura et Migo  /  polysaccharide  /  pharmacological activity  /  mechanism  /  gut microbiota
Le SUN, Xiao-mei CHEN, Chong-ming WU, Shun-xing GUO. Advances and prospects of pharmacological activities of Dendrobium officinale Kimura et Migo polysaccharides[J]. Acta Pharmaceutica Sinica, 2020 , 55 (10) : 2322 -2329 . DOI: 10.16438/j.0513-4870.2020-0126
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Year 2020 volume 55 Issue 10
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doi: 10.16438/j.0513-4870.2020-0126
  • Receive Date：2020-02-14
  • Online Date：2026-01-23
  • Published：2020-10-12
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  • Received：2020-02-14
  • Revised：2020-05-11
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    Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100193, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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