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Research progress on the West Nile virus inhibitors
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Rui-peng LIANG, Tong ZHAO, Peng ZHAN*, Xin-yong LIU*
Acta Pharmaceutica Sinica | 2020, 55(4) : 763 - 772
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Acta Pharmaceutica Sinica | 2020, 55(4): 763-772
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Research progress on the West Nile virus inhibitors
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Rui-peng LIANG, Tong ZHAO, Peng ZHAN*, Xin-yong LIU*
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  • Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Published: 2020-04-12 doi: 10.16438/j.0513-4870.2019-1017
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West Nile virus is a flavivirus transmitted by culex mosquitoes. People are generally susceptible to it, West Nile virus infection can cause west Nile fever, which can develop West Nile viral encephalitis and even lead to death. There are currently no approved specific antiviral drugs against West Nile virus. Therefore, seeking effective West Nile virus inhibitors is a hot topic in current community of medicinal chemistry. In this article, based on the main targets of West Nile virus, we summarize the new progress research on West Nile virus inhibitors.

West Nile virus  /  West Nile fever  /  inhibitor  /  drug target  /  drug design
Rui-peng LIANG, Tong ZHAO, Peng ZHAN, Xin-yong LIU. Research progress on the West Nile virus inhibitors[J]. Acta Pharmaceutica Sinica, 2020 , 55 (4) : 763 -772 . DOI: 10.16438/j.0513-4870.2019-1017
Year 2020 volume 55 Issue 4
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doi: 10.16438/j.0513-4870.2019-1017
  • Receive Date:2019-12-13
  • Online Date:2026-01-20
  • Published:2020-04-12
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  • Received:2019-12-13
  • Revised:2019-12-31
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    Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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