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Strategy for the identification and quantitative analysis of the phytochemicals of traditional Chinese medicine by LC-MS/MS
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Pan YAN1, Shuai-long JIA1, Sen LI2, Zhi-feng DU1, Hong-liang JIANG1, *
Acta Pharmaceutica Sinica | 2020, 55(7) : 1494 - 1503
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Acta Pharmaceutica Sinica | 2020, 55(7): 1494-1503
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Strategy for the identification and quantitative analysis of the phytochemicals of traditional Chinese medicine by LC-MS/MS
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Pan YAN1, Shuai-long JIA1, Sen LI2, Zhi-feng DU1, Hong-liang JIANG1, *
Affiliations
  • 1. Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China
  • 2. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Published: 2020-07-12 doi: 10.16438/j.0513-4870.2019-0973
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Traditional Chinese medicine (TCM) has made numerous contributions to the prosperity of China. However, the phytochemicals of TCM are complex, and there are significant differences in relative content. The material basis of TCM has restricted the modernization of TCM. Liquid chromatography-mass spectrometry (LCMS) combines the high separation performance of chromatography and the high sensitivity of mass spectrometry. It has been widely used in the analysis of natural medicines and can greatly promote the development of TCM. Many studies have focused on the comprehensive characterization of phytochemicals, building a strategy for the rapid, accurate and systematic analysis of the chemical components of TCM through the integration of different mass spectrometric techniques, and laying the foundation for quality control and rational utilization of TCM.

traditional Chinese medicine  /  phytochemicals  /  LC-MS/MS  /  fragmentation rule  /  quality control
Pan YAN, Shuai-long JIA, Sen LI, Zhi-feng DU, Hong-liang JIANG. Strategy for the identification and quantitative analysis of the phytochemicals of traditional Chinese medicine by LC-MS/MS[J]. Acta Pharmaceutica Sinica, 2020 , 55 (7) : 1494 -1503 . DOI: 10.16438/j.0513-4870.2019-0973
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Article Info
doi: 10.16438/j.0513-4870.2019-0973
  • Receive Date：2019-11-28
  • Online Date：2026-01-21
  • Published：2020-07-12
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  • Received：2019-11-28
  • Revised：2020-01-15
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    1. Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China
    2. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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