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Rapid characterization of saponins in fresh and steamed notoginseng root slices by liquid extraction, surface analysis-mass spectrometry
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Mei TIAN1, Lin-nan LI1, Yuan-gui YANG1, Li YANG1, 2, *, Zheng-tao WANG1, 2
Acta Pharmaceutica Sinica | 2020, 55(1) : 123 - 130
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Acta Pharmaceutica Sinica | 2020, 55(1): 123-130
• Original Articles •
Rapid characterization of saponins in fresh and steamed notoginseng root slices by liquid extraction, surface analysis-mass spectrometry
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Mei TIAN1, Lin-nan LI1, Yuan-gui YANG1, Li YANG1, 2, *, Zheng-tao WANG1, 2
Affiliations
  • 1. The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • 2. Shanghai R & D Center for Standardization of Chinese Medicines, Shanghai 201203, China
Published: 2020-01-12 doi: 10.16438/j.0513-4870.2019-0592
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Notoginseng (Sanqi), the root of Panax notoginseng (Burk.) F. H. Chen (Araliaceae), is one of the most valuable traditional Chinese medicines (TCM). It has been widely used in China with a long history for treatment of haemorrhage, edema, and cardiovascular disorders. Steamed P. notoginseng has been considered to have stronger therapeutic functions than raw P. notoginseng in the treatment of tumors, cardiovascular diseases, etc. Saponins are the principal chemical and pharmacological constituents in P. notoginseng. Thus, it is of great importance to determine the constituent saponins and determine any differences between fresh P. notoginseng and steamed P. notoginseng. We used a rapid and direct analytical method based on liquid extraction surface analysis combined with mass spectrometry (LESA-MS) to identify saponins in the xylem, phloem and cambium of fresh and steamed P. notoginseng root slices. The results revealed that ginsenosides Rg1, Rb1, Re, Rd, notoginsenoside R1 and their malonyl group versions were most abundant in fresh root slices, while in steamed slices ginsenosides Rg5, Rk1 and other minor polar components could be detected, and the relative content of large polar components was lower. The described method is fast, robust and sensitive and the process does not need traditional and cumbersome pretreatment such as crushing, extraction and separation. It is the first non-destructive study on the differences in saponins between fresh and steamed P. notoginseng root slices.

liquid extraction surface analysis  /  mass spectrometry  /  Panax notoginseng  /  saponin compound  /  rapid identification
Mei TIAN, Lin-nan LI, Yuan-gui YANG, Li YANG, Zheng-tao WANG. Rapid characterization of saponins in fresh and steamed notoginseng root slices by liquid extraction, surface analysis-mass spectrometry[J]. Acta Pharmaceutica Sinica, 2020 , 55 (1) : 123 -130 . DOI: 10.16438/j.0513-4870.2019-0592
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Year 2020 volume 55 Issue 1
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Article Info
doi: 10.16438/j.0513-4870.2019-0592
  • Receive Date：2019-07-23
  • Online Date：2026-01-20
  • Published：2020-01-12
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History
  • Received：2019-07-23
  • Revised：2019-08-20
Funding
Affiliations
    1. The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2. Shanghai R & D Center for Standardization of Chinese Medicines, Shanghai 201203, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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