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Research progress of circular RNA in regulating vascular endothelial dysfunction
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Yi-xiu ZHAO, Xue LIU, Yan ZHANG
Acta Pharmaceutica Sinica | 2019, 54(2) : 228 - 234
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Acta Pharmaceutica Sinica | 2019, 54(2): 228-234
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Research progress of circular RNA in regulating vascular endothelial dysfunction
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Yi-xiu ZHAO, Xue LIU, Yan ZHANG
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  • Department of Pharmacology(State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China
Published: 2019-02-12 doi: 10.16438/j.0513-4870.2018-0790
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Atherosclerosis refers to vascular pathological changes in which vascular lumen was narrowed or blocked by cholesterol or fat existed in vascular endothelium, which could induce serious cardiovascular events. The pathogenesis of atherosclerosis is complicated extremely. Vascular endothelial dysfunction initiated the plague formation and deterioration, which determined the prognosis of atherosclerosis. Circular RNA (circRNA) is a special endogenous non-coding RNA, which has become a research hotpot in the field of non-coding RNA. This review aims to bring together the recent research on the pathogenesis and pathological process of endothelial dysfunction, and the regulative effect of circRNA on it. Our article will provide new targets and new ideas for the research and development of anti-atherosclerosis drugs.

noncoding RNA  /  vascular endothelium  /  atherosclerosis  /  apoptosis  /  hyperglycemia  /  hypoxia
Yi-xiu ZHAO, Xue LIU, Yan ZHANG. Research progress of circular RNA in regulating vascular endothelial dysfunction[J]. Acta Pharmaceutica Sinica, 2019 , 54 (2) : 228 -234 . DOI: 10.16438/j.0513-4870.2018-0790
Year 2019 volume 54 Issue 2
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Article Info
doi: 10.16438/j.0513-4870.2018-0790
  • Receive Date:2018-08-28
  • Online Date:2026-01-26
  • Published:2019-02-12
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  • Received:2018-08-28
  • Revised:2018-09-29
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    Department of Pharmacology(State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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