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Antitumor status analysis on the co-delivery systems regarding the active ingredients of Chinese herbs combined with chemotherapeutic drugs
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Jin-feng SHI, Jie LI, Xiao-qin YANG, Yue ZHANG, Shi-cai YANG, Yao-yao LUO, Jin-ming ZHANG*, Chao-mei FU
Acta Pharmaceutica Sinica | 2019, 54(2) : 258 - 268
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Acta Pharmaceutica Sinica | 2019, 54(2): 258-268
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Antitumor status analysis on the co-delivery systems regarding the active ingredients of Chinese herbs combined with chemotherapeutic drugs
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Jin-feng SHI, Jie LI, Xiao-qin YANG, Yue ZHANG, Shi-cai YANG, Yao-yao LUO, Jin-ming ZHANG*, Chao-mei FU
Affiliations
  • Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Key Laboratory of Systematic Research, Development and Utilization of Chinese Medicine Resources in Sichuan Province-State Key Laboratory Breeding Base Co-founded by Sichuan Province and MOST, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Published: 2019-02-12 doi: 10.16438/j.0513-4870.2018-0659
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Anti-tumor intervention using a combination of drugs shows unique advantages in research and clinical practice. Active ingredients of Chinese herbal medicines can offer many advantages, such as high efficiency, low toxicity, wide effect and multiple targets. At present, the combination active ingredients of Chinese herbal and chemotherapy drugs have attracted increased attention. Nano-drug delivery system provides a good carrier platform for anti-tumor drugs. Nano-carrier-mediated drug combination is a promising strategy. In this paper, we review the mechanisms of the anti-tumor effects of active ingredients of traditional Chinese medicine combined with chemotherapeutic drugs and consider the advantages of drug-loaded nanoparticles, the types and characteristics of carriers. The aim is to provide a reference for the research of effective regimen for anti-tumor therapy.

nanocarrier  /  co-delivery  /  Chinese herb  /  active ingredient  /  chemotherapy drug
Jin-feng SHI, Jie LI, Xiao-qin YANG, Yue ZHANG, Shi-cai YANG, Yao-yao LUO, Jin-ming ZHANG, Chao-mei FU. Antitumor status analysis on the co-delivery systems regarding the active ingredients of Chinese herbs combined with chemotherapeutic drugs[J]. Acta Pharmaceutica Sinica, 2019 , 54 (2) : 258 -268 . DOI: 10.16438/j.0513-4870.2018-0659
Year 2019 volume 54 Issue 2
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Article Info
doi: 10.16438/j.0513-4870.2018-0659
  • Receive Date:2018-07-19
  • Online Date:2026-01-26
  • Published:2019-02-12
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  • Received:2018-07-19
  • Revised:2018-08-14
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    Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Key Laboratory of Systematic Research, Development and Utilization of Chinese Medicine Resources in Sichuan Province-State Key Laboratory Breeding Base Co-founded by Sichuan Province and MOST, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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