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Recent advances in the research on pharmacological actions and quantitative analyses of naphthoquinones in Chinese medicinal herb "Zicao"
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Min CHENG1, Jun TANG2, *, Shan-shan LI2
Acta Pharmaceutica Sinica | 2018, 53(12) : 2026 - 2039
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Acta Pharmaceutica Sinica | 2018, 53(12): 2026-2039
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Recent advances in the research on pharmacological actions and quantitative analyses of naphthoquinones in Chinese medicinal herb "Zicao"
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Min CHENG1, Jun TANG2, *, Shan-shan LI2
Affiliations
  • 1. Wuhan Institute for Drug and Medical Device Control, Wuhan 430075, China
  • 2. Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China
Published: 2018-12-12 doi: 10.16438/j.0513-4870.2018-0583
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Naphthoquinones are a kind of important active ingredients in the traditional Chinese medicinal herb "Zicao". In recent years, researches on pharmacology and clinical application of naphthoquinones in Zicao have been gradually deepened and made extensive progress around the world. On the other hand, the plant origins of the herbal materials of Zicao in market are complex and their qualities are quite different, thus more and more studies have been focused on the quantitative determination and quality assessment of the medicinal herb as well as its products by using various naphthoquinones as quality chemical markers. In this paper, we review recent advances in the research on pharmacological actions and multi-components content determination of shikonin/alkannin and its derivatives in Zicao so as to provide a scientific guidance for further research and development of medicinal resource of Zicao, and to establish more comprehensive and systematic method for their quality control and evaluation.

Zicao  /  naphthoquinones  /  pharmacological action  /  quality marker  /  quantitative analysis  /  quality evaluation
Min CHENG, Jun TANG, Shan-shan LI. Recent advances in the research on pharmacological actions and quantitative analyses of naphthoquinones in Chinese medicinal herb "Zicao"[J]. Acta Pharmaceutica Sinica, 2018 , 53 (12) : 2026 -2039 . DOI: 10.16438/j.0513-4870.2018-0583
Year 2018 volume 53 Issue 12
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Article Info
doi: 10.16438/j.0513-4870.2018-0583
  • Receive Date:2018-06-23
  • Online Date:2026-01-15
  • Published:2018-12-12
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  • Received:2018-06-23
  • Revised:2018-08-31
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Affiliations
    1. Wuhan Institute for Drug and Medical Device Control, Wuhan 430075, China
    2. Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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