Home Journals Articles Updates About
CN
image
收藏切换
A new polyketide from a sponge-derived fungus
收藏切换
PDF
Yong-qi TIAN1, *, Shu-ting LIN1, Yong-hong LIU2, *
Acta Pharmaceutica Sinica | 2018, 53(7) : 1134 - 1138
Less
收藏切换
Acta Pharmaceutica Sinica | 2018, 53(7): 1134-1138
• ORIGINAL ARTICLES·Medicinal Chemistry •
A new polyketide from a sponge-derived fungus
Full
Yong-qi TIAN1, *, Shu-ting LIN1, Yong-hong LIU2, *
Affiliations
  • 1. College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China
  • 2. Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
Published: 2018-07-12 doi: 10.16438/j.0513-4870.2018-0448
Outline
收藏切换

A new polyketide:3R, 5R-(-)-talaroflavone (2), along with 15 known compounds were isolated from a EtOAc extract of a sponge-derived fungus Alternaria sp. F49. Compounds 1-2 and 3-4 were separated as two pairs of enantiomers by chiral HPLC from Ⅰ and Ⅱ. The structures of compounds 1-16 were elucidated by means of NMR and MS. Furthermore, the absolute configurations of compounds 1-2 were determined by single crystal X-ray diffraction experiment and CD analyses. Compounds 6, 8-10 were isolated from this genus (Alternaria sp.) for the first time. Compound 16 showed moderate COX-2 enzyme inhibitory activity with IC50 of 7.3 μmol·L-1.

sponge-derived fungus  /  Alternaria sp. F49  /  spectroscopic analysis  /  secondary metabolites
Yong-qi TIAN, Shu-ting LIN, Yong-hong LIU. A new polyketide from a sponge-derived fungus[J]. Acta Pharmaceutica Sinica, 2018 , 53 (7) : 1134 -1138 . DOI: 10.16438/j.0513-4870.2018-0448
Appendix
Less
Year 2018 volume 53 Issue 7
PDF
127
43
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2018-0448
  • Receive Date：2018-05-15
  • Online Date：2026-01-15
  • Published：2018-07-12
Article Data
Affiliations
History
  • Received：2018-05-15
  • Revised：2018-05-21
Funding
Affiliations
    1. College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, China
    2. Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2018-0448
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House