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The current application of stem cell based therapy in pulmonary hypertension
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Ding ZHANG, Jun YANG*
Acta Pharmaceutica Sinica | 2018, 53(11) : 1778 - 1783
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Acta Pharmaceutica Sinica | 2018, 53(11): 1778-1783
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The current application of stem cell based therapy in pulmonary hypertension
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Ding ZHANG, Jun YANG*
Affiliations
  • Department of Cell Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100050, China
Published: 2018-11-12 doi: 10.16438/j.0513-4870.2018-0347
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Pulmonary hypertension (PH) is a progressive cardiopulmonary disease with high mortality and increased prevalence. The target therapy of pulmonary hypertension is mainly dependent on vasodilation, but how to improve vascular remodeling with stem cell therapy has not been fully understood. Over the past ten years, the researches on endothelial progenitor cells, mesenchymal stem cells and pluripotent cells have brought the hope to patients with pulmonary hypertension. This article mainly introduces the latest progress of stem cell technology in the intervention of pulmonary hypertension, and discusses the problems in the application.

pulmonary hypertension  /  stem/progenitor cells  /  cell therapy  /  vascular remodeling
Ding ZHANG, Jun YANG. The current application of stem cell based therapy in pulmonary hypertension[J]. Acta Pharmaceutica Sinica, 2018 , 53 (11) : 1778 -1783 . DOI: 10.16438/j.0513-4870.2018-0347
Year 2018 volume 53 Issue 11
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Article Info
doi: 10.16438/j.0513-4870.2018-0347
  • Receive Date:2018-04-16
  • Online Date:2026-01-15
  • Published:2018-11-12
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  • Received:2018-04-16
  • Revised:2018-06-04
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    Department of Cell Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100050, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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