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Advances in immunotherapy of Alzheimer's disease with traditional Chinese medicine
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Sha-sha WANG1, Zhao ZHANG2, Xin ZHANG1, Qian LONG1, Wen-bin HE1, Nai-hong CHEN1, 2, *
Acta Pharmaceutica Sinica | 2018, 53(7) : 1023 - 1029
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Acta Pharmaceutica Sinica | 2018, 53(7): 1023-1029
• SPECIAL REPORTS·Pharmacology of Chinese Medicine and Nervous Diseases •
Advances in immunotherapy of Alzheimer's disease with traditional Chinese medicine
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Sha-sha WANG1, Zhao ZHANG2, Xin ZHANG1, Qian LONG1, Wen-bin HE1, Nai-hong CHEN1, 2, *
Affiliations
  • 1. Shanxi University of Traditional Chinese Medicine, Taiyuan 030619, China
  • 2. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2018-07-12 doi: 10.16438/j.0513-4870.2017-1013
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Alzheimer's disease (AD) is a type of common neurodegenerative disease.The main clinical symptom of the disease is progressive cognitive dysfunction, which has no effective therapy yet.With the in-depth immunology study in the central nervous system, studies in different fields such as preclinical phase, genetics and bioinformatics have shown that immune dysfunction contribute to the pathogenesis of AD, including the beginning, maintenance and deterioration stage in AD.China has a wealth of natural medicine resources and clinical experiences.A large number of natural drugs and effective components both can regulate the immune function and ameliorate the symptoms in AD.This review summarizes the researches of ameliorating the symptoms in AD through immunization regulation in recent years with an aim to provide new ideas and clues in the study of new anti-AD drugs using natural medicines.

Alzheimer's disease  /  immunotherapy  /  inflammation  /  traditional Chinese medicine
Sha-sha WANG, Zhao ZHANG, Xin ZHANG, Qian LONG, Wen-bin HE, Nai-hong CHEN. Advances in immunotherapy of Alzheimer's disease with traditional Chinese medicine[J]. Acta Pharmaceutica Sinica, 2018 , 53 (7) : 1023 -1029 . DOI: 10.16438/j.0513-4870.2017-1013
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Article Info
doi: 10.16438/j.0513-4870.2017-1013
  • Receive Date：2017-10-16
  • Online Date：2026-01-15
  • Published：2018-07-12
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History
  • Received：2017-10-16
  • Revised：2017-11-29
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Affiliations
    1. Shanxi University of Traditional Chinese Medicine, Taiyuan 030619, China
    2. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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