Home Journals Articles Updates About
CN
image
收藏切换
Review and prospect on preparation technology of drug nanocrystals in the past thirty years
收藏切换
PDF
Peng-fei YUE*, Yang LIU, Jin XIE, Ying-chong CHEN, Ming YANG*
Acta Pharmaceutica Sinica | 2018, 53(4) : 529 - 537
Less
收藏切换
Acta Pharmaceutica Sinica | 2018, 53(4): 529-537
• REVIEWS •
Review and prospect on preparation technology of drug nanocrystals in the past thirty years
Full
Peng-fei YUE*, Yang LIU, Jin XIE, Ying-chong CHEN, Ming YANG*
Affiliations
  • Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, State Key Laboratory of Innovative Drug and High Efficiency and Energy Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
Published: 2018-04-12 doi: 10.16438/j.0513-4870.2017-0920
Outline
收藏切换

Nanocrystals is a hot topic of poorly soluble drug delivery system under development. Nanocrystals is different from the nanoparticles for drug unloading in polymer materials, and nanocrystals is different from solid dispersion system, in which the drug maintains crystals state. Nanocrystals has a simple preparation process, represents an effective technology in the improvement of solubility and bioavailability of poorly soluble drugs, and has a very promising industrialization application and development potential. In this paper, we retrospect the development history of drug nanocrystals technology, review development of the preparation methods of nanocrystals, and analyze the existing problems to provide a reference to the development of drug nanocrystals preparation.

nanocrystal  /  preparation technology  /  bottom-up  /  top-down  /  combinative technology
Peng-fei YUE, Yang LIU, Jin XIE, Ying-chong CHEN, Ming YANG. Review and prospect on preparation technology of drug nanocrystals in the past thirty years[J]. Acta Pharmaceutica Sinica, 2018 , 53 (4) : 529 -537 . DOI: 10.16438/j.0513-4870.2017-0920
Appendix
Less
Year 2018 volume 53 Issue 4
PDF
197
77
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2017-0920
  • Receive Date：2017-09-15
  • Online Date：2026-01-15
  • Published：2018-04-12
Article Data
Affiliations
History
  • Received：2017-09-15
  • Revised：2017-10-31
Funding
Affiliations
    Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, State Key Laboratory of Innovative Drug and High Efficiency and Energy Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2017-0920
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House