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Advance in the in vivo metabolism and the biological effects of selenium
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Li-bin PAN1, Hui-zheng FAN2, Jian-dong JIANG1, Yan WANG1, *
Acta Pharmaceutica Sinica | 2017, 52(12) : 1849 - 1858
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Acta Pharmaceutica Sinica | 2017, 52(12): 1849-1858
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Advance in the in vivo metabolism and the biological effects of selenium
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Li-bin PAN1, Hui-zheng FAN2, Jian-dong JIANG1, Yan WANG1, *
Affiliations
  • 1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • 2. South-Central University For Nationalities university, Wuhan 430070, China
Published: 2017-12-15 doi: 10.16438/j.0513-4870.2017-0905
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Selenium (molecular weight 78.96), is a necessary non-metallic trace elements. In recent years, more and more studies have found that selenium is closely related to human disease and could not be ignored. In this paper, we elucidate the in vivo absorption and metabolism of selenium; the active substance-selenoprotein P and so on; the correlation between selenium and pathogenesis of various diseases such as cardiovascular disease, AD/PD neurodegenerative diseases and cancer, etc. The aim is to achieve a more comprehensive understanding of selenium, and to research the in vivo process and the biological effects of selenium. At the same time, selenoproteins and related mechanisms might also be a new target for drug research and discovery.

selenium  /  selenoprotein  /  biological effect  /  metabolism
Li-bin PAN, Hui-zheng FAN, Jian-dong JIANG, Yan WANG. Advance in the in vivo metabolism and the biological effects of selenium[J]. Acta Pharmaceutica Sinica, 2017 , 52 (12) : 1849 -1858 . DOI: 10.16438/j.0513-4870.2017-0905
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Article Info
doi: 10.16438/j.0513-4870.2017-0905
  • Receive Date：2017-09-12
  • Online Date：2026-01-14
  • Published：2017-12-15
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History
  • Received：2017-09-12
  • Revised：2017-11-18
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Affiliations
    1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    2. South-Central University For Nationalities university, Wuhan 430070, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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