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A new triterpenoid from roots of Psidium guajava
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Cai-ying PENG, Ying-zheng HUANG, Jian-qun LIU, Hui-lian HUANG, Ji-cheng SHU*
Acta Pharmaceutica Sinica | 2017, 52(11) : 1731 - 1736
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Acta Pharmaceutica Sinica | 2017, 52(11): 1731-1736
ORIGINAL ARTICLES
A new triterpenoid from roots of Psidium guajava
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Cai-ying PENG, Ying-zheng HUANG, Jian-qun LIU, Hui-lian HUANG, Ji-cheng SHU*
Affiliations
  • Key Laboratory of Modern Preparation of Traditional Chinese Medicines, Ministry of Education, Jiangxi University of Traditional Chinese Medicines, Nanchang 330004, China
Published: 2017-11-12 doi: 10.16438/j.0513-4870.2017-0565
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To investigated the chemical constituents of the roots of Psidium guajava, we isolated seven compounds by silica gel column chromatography.These include oleanane derivatives, 2 α, 3β, 6β, 23-tetrahydroxylurs-12, 20(30)-dien-28-oic acid β-D-glucopyranoside (1), 2α, 3β, 6β, 23-tetrahydroxylurs-12, 18-dien-28-oic acid β-D-glucopyranoside (2), 2α, 3β, 23-trihydroxylurs-12, 18-dien-28-oic acid β-D-glucopyranoside (3), nigaichigoside F1(4), asiaticoside C (5), 2α, 3β, 6β, 19α, 23-pentahydroxylurs-12, 18-dien-28-oic acid β-Dglucopyranoside (6) and 2α, 3β, 19α, 23-tetrahydroxylurs-12-en-28-oic acid (7).Their structures were elucidated on the basis of spectral analysis with reference to the published data.Compound 1 is brand new, compounds 2-6 were first isolated from this plant.The new compound was evaluated for their cytotoxic activity against human hepatoma Bel 7402 in vitro.The results were expressed as the ratio of inhibiting Bel 7402 cells growth by comparing to untreated cells.The new compound (concentration:25 μmol·L-1) showed the ratio values of 52.5%.

Psidium guajava  /  chemical constituent  /  ursane  /  triterpenoid  /  cytotoxic activity
Cai-ying PENG, Ying-zheng HUANG, Jian-qun LIU, Hui-lian HUANG, Ji-cheng SHU. A new triterpenoid from roots of Psidium guajava[J]. Acta Pharmaceutica Sinica, 2017 , 52 (11) : 1731 -1736 . DOI: 10.16438/j.0513-4870.2017-0565
Year 2017 volume 52 Issue 11
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doi: 10.16438/j.0513-4870.2017-0565
  • Receive Date:2017-06-13
  • Online Date:2026-01-14
  • Published:2017-11-12
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  • Received:2017-06-13
  • Revised:2017-07-04
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    Key Laboratory of Modern Preparation of Traditional Chinese Medicines, Ministry of Education, Jiangxi University of Traditional Chinese Medicines, Nanchang 330004, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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