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Research progress of the exosomes as drug delivery vehicles of Chinese herbal drugs
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Peng YUAN1, Xiao-chen GUO2, Jun-ping ZHANG2, *, Shi-chao LÜ2, Ya-ping ZHU2
Acta Pharmaceutica Sinica | 2017, 52(11) : 1667 - 1672
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Acta Pharmaceutica Sinica | 2017, 52(11): 1667-1672
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Research progress of the exosomes as drug delivery vehicles of Chinese herbal drugs
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Peng YUAN1, Xiao-chen GUO2, Jun-ping ZHANG2, *, Shi-chao LÜ2, Ya-ping ZHU2
Affiliations
  • 1. Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
  • 2. The First Affiliated Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Published: 2017-11-12 doi: 10.16438/j.0513-4870.2017-0547
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As a new carrier of intercellular information, the exosomes is widely regarded as a natural drug carrier for its extensive distribution, non-immunity and targeting in human body. Chinese herbal drugs act at multiple targets and through different pathways in the prevention and treatment of diseases, but the preparation is relatively simple, there is a low solubility in the effective ingredients and low bioavailability, which limit the efficacy of the medicine. Using the new drug delivery approach of the exosomes, it is better to deliver the effective components to target cells. In this review, we reviewed the biological characteristics of exosomes and its application as a carrier of Chinese herbal drugs.

exosome  /  drug carrier  /  Chinese herbal drug  /  nanotechnology  /  targeting  /  bioavailability  /  water-insoluble drug
Peng YUAN, Xiao-chen GUO, Jun-ping ZHANG, Shi-chao LÜ, Ya-ping ZHU. Research progress of the exosomes as drug delivery vehicles of Chinese herbal drugs[J]. Acta Pharmaceutica Sinica, 2017 , 52 (11) : 1667 -1672 . DOI: 10.16438/j.0513-4870.2017-0547
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Article Info
doi: 10.16438/j.0513-4870.2017-0547
  • Receive Date：2017-06-07
  • Online Date：2026-01-14
  • Published：2017-11-12
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History
  • Received：2017-06-07
  • Revised：2017-07-03
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Affiliations
    1. Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
    2. The First Affiliated Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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