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Applications of microfluidic technology to delivery of nanoparticulate drug
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Xi-ying GUO, Wei WEI, Jian-cheng WANG*, Qiang ZHANG
Acta Pharmaceutica Sinica | 2017, 52(10) : 1515 - 1523
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Acta Pharmaceutica Sinica | 2017, 52(10): 1515-1523
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Applications of microfluidic technology to delivery of nanoparticulate drug
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Xi-ying GUO, Wei WEI, Jian-cheng WANG*, Qiang ZHANG
Affiliations
  • Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China
Published: 2017-10-12 doi: 10.16438/j.0513-4870.2017-0399
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Microfluidics is a technology that involves the use of micro-nanoscale pipelines to manipulate fluid mixing. Precise control of the mixing process of laminar flows or liquid droplets by using microfluidics will contribute to the preparation of nanoparticles, which are difficult to be achieved by the conventional methods. Based on the progress in delivery systems of nanoparticulate drug, we provide a summary to introduce the applications of microfluidics in construction of nanoparticulate drug delivery system such as liposomes, polymer nanoparticles and hybrid nanoparticles, and analyze the assembling mechanisms of different nanostructures by using microfluidic precise control. This review will provide a reference in utilization of microfluidic technology more scientifically and reasonably.

microfluidics  /  nanoparticulate drug delivery system  /  preparation  /  structure-activity rela-tionship
Xi-ying GUO, Wei WEI, Jian-cheng WANG, Qiang ZHANG. Applications of microfluidic technology to delivery of nanoparticulate drug[J]. Acta Pharmaceutica Sinica, 2017 , 52 (10) : 1515 -1523 . DOI: 10.16438/j.0513-4870.2017-0399
Year 2017 volume 52 Issue 10
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Article Info
doi: 10.16438/j.0513-4870.2017-0399
  • Receive Date:2017-04-25
  • Online Date:2026-01-14
  • Published:2017-10-12
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  • Received:2017-04-25
  • Revised:2017-05-12
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    Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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