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Current status of ion channels as drug targets for diabetic neuropathic pain
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Yu ZHOU, Xiao-liang WANG*, Hai-bo YU*
Acta Pharmaceutica Sinica | 2017, 52(3) : 355 - 361
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Acta Pharmaceutica Sinica | 2017, 52(3): 355-361
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Current status of ion channels as drug targets for diabetic neuropathic pain
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Yu ZHOU, Xiao-liang WANG*, Hai-bo YU*
Affiliations
  • State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2017-03-12 doi: 10.16438/j.0513-4870.2016-0928
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Diabetic neuropathic pain (DNP) is the most common chronic complication of diabetes mellitus, significantly affecting people's quality of life. Studies have indicated that ion channels play a very important role in the occurrence of DNP. This review provides a summary in the role of ion channels in diabetic neuropathic pain and treatment strategies for diabetic neuropathy targeting ion channels.

diabetic neuropathic pain  /  ion channel  /  potassium channel  /  sodium channel  /  calcium channel
Yu ZHOU, Xiao-liang WANG, Hai-bo YU. Current status of ion channels as drug targets for diabetic neuropathic pain[J]. Acta Pharmaceutica Sinica, 2017 , 52 (3) : 355 -361 . DOI: 10.16438/j.0513-4870.2016-0928
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Year 2017 volume 52 Issue 3
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Article Info
doi: 10.16438/j.0513-4870.2016-0928
  • Receive Date：2016-09-21
  • Online Date：2026-01-14
  • Published：2017-03-12
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  • Received：2016-09-21
  • Revised：2016-10-25
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    State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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