收藏切换
Research on the application of machine learning related techniques in the classification of Astragali Radix characterized by flavonoids
收藏切换
PDF
Yan SHI1, Ning LI2, Feng WEI1, *, Shuang-cheng MA1
Chinese Journal of Pharmaceutical Analysis | 2024, 44(5) : 866 - 873
Less
收藏切换
Chinese Journal of Pharmaceutical Analysis | 2024, 44(5): 866-873
Quality Control
Research on the application of machine learning related techniques in the classification of Astragali Radix characterized by flavonoids
Full
Yan SHI1, Ning LI2, Feng WEI1, *, Shuang-cheng MA1
Affiliations
  • 1.National Institutes for Food and Drug Control, Beijing 102629, China
  • 2.Beijing Institute for Drug Control, Beijing 102206, China
Published: 2024-05-31 doi: 10.16155/j.0254-1793.2024.05.15
Outline
收藏切换
Objective:

To establish a three classification model for cultivated,semi-wild,and wild Astragali Radix characterized by flavonoids,and explore and evaluate the application of techniques of automated machine learning and data augmentation in the field of drug analysis.

Methods:

Firstly,correlation analysis and principal component analysis were conducted on the flavonoid content data of Astragali Radix,and models of decision tree and logistic regression were established to analyze the importance of flavonoid components based on the models. Then,using the AutoGluon framework with 5 as num_bag_folds,2 sets of 30 models respectively through 64 batches of real data and 600 batches of virtual data generated based on real data with the TVAE table data generation algorithm for training were obtained,and these models were evaluated by accuracy.

Results:

The analysis of machine learning models,indicated that formononetin,campanulin and onospin played the important roles in the quality control of Astragali Radix,especially for the source grade control. The accuracy of model prediction showed that the models based on Neural Net and tree-model always had the best classification effect for Astragali Radix. The virtual data generated by data augmentation technique is basically consistent with the actual data in terms of the accuracy trend of the model training process.

Conclusion:

Related techniques of machine learning have good application value in the classification of Astragali Radix characterized by flavonoids.

Astragali Radix  /  flavonoids  /  campanulin  /  onospin  /  calycosin  /  kaempferol  /  isorhamnetin  /  formononetin  /  machine learning  /  artificial intelligence  /  data augmentation
Yan SHI, Ning LI, Feng WEI, Shuang-cheng MA. Research on the application of machine learning related techniques in the classification of Astragali Radix characterized by flavonoids[J]. Chinese Journal of Pharmaceutical Analysis, 2024 , 44 (5) : 866 -873 . DOI: 10.16155/j.0254-1793.2024.05.15
Year 2024 volume 44 Issue 5
PDF
59
25
Cite this Article
BibTeX
Article Info
doi: 10.16155/j.0254-1793.2024.05.15
  • Receive Date:2023-07-19
  • Online Date:2026-03-20
  • Published:2024-05-31
Article Data
Affiliations
History
  • Received:2023-07-19
Affiliations
    1.National Institutes for Food and Drug Control, Beijing 102629, China
    2.Beijing Institute for Drug Control, Beijing 102206, China
References
Share
https://castjournals.cast.org.cn/joweb/ywfxzz/EN/10.16155/j.0254-1793.2024.05.15
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT