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Research progress on the mechanism of action and bioactivity methods of human thyroid-stimulating hormone
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Jing GAO1, 2, Cheng-gang LIANG2, **, Jing LI2, **
Chinese Journal of Pharmaceutical Analysis | 2024, 44(7) : 1105 - 1112
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Chinese Journal of Pharmaceutical Analysis | 2024, 44(7): 1105-1112
• Review & Monography •
Research progress on the mechanism of action and bioactivity methods of human thyroid-stimulating hormone
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Jing GAO1, 2, Cheng-gang LIANG2, **, Jing LI2, **
Affiliations
  • 1.China Pharmaceutical University College of Life Science and Technology, Nanjing 210009, China
  • 2.National Institutes for Food and Drug Control, State Key Laboratory of Drug Regulatory Science, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, Beijing 102629, China
Published: 2024-07-31 doi: 10.16155/j.0254-1793.2024-0226
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Thyroid-stimulating hormone (TSH) is a glycoprotein hormone produced by the anterior pituitary. It can regulate the synthesis and secretion of thyroid hormone in thyroid follicular cells, which has important physiological significance. As a drug, it has important application value. Biological activity detection is an effective and necessary to evaluate its quality. This article discusses the signal transduction mechanism of thyroid stimulating hormone, the clinical diagnosis and treatment of thyroid stimulating hormone, and the determination method of biological activity.

thyroid-stimulating hormone  /  signal transduction mechanism  /  diagnosis and treatment  /  osteoporosis  /  thyroid cancer  /  polycystic ovary syndrome  /  biological activity assay
Jing GAO, Cheng-gang LIANG, Jing LI. Research progress on the mechanism of action and bioactivity methods of human thyroid-stimulating hormone[J]. Chinese Journal of Pharmaceutical Analysis, 2024 , 44 (7) : 1105 -1112 . DOI: 10.16155/j.0254-1793.2024-0226
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Year 2024 volume 44 Issue 7
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Article Info
doi: 10.16155/j.0254-1793.2024-0226
  • Receive Date：2024-04-07
  • Online Date：2026-03-13
  • Published：2024-07-31
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  • Received：2024-04-07
Funding
Affiliations
    1.China Pharmaceutical University College of Life Science and Technology, Nanjing 210009, China
    2.National Institutes for Food and Drug Control, State Key Laboratory of Drug Regulatory Science, NHC Key Laboratory of Research on Quality and Standardization of Biotech Products, Beijing 102629, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
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小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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