To establish an HPLC method for the simultaneous determination of eight components including salvianic acid A sodium，geniposidic acid，phellodendrine，salvianolic acid B，palmatine，berberine，atractylodin，tanshinone Ⅱ_A in Shuangshi Tonglin capsules.

The determination was performed on a Capcell Pak MG Ⅱ C₁₈ column (250 mm×4.6 mm，5 μm) with the mobile phase consisting of acetonitrile-water(containing 0.1% phosphoric acid)-water(containing 0.1% phosphoric acid and 0.2% triethylamine，pH 6.0) in a gradient mode at a flow rate of 1.0 mL·min^-1. The column temperature was set at 30 ℃，the injection volume was 10 μL，and the detection wavelength was 280 nm (0-13.4 min）for salvianic acid A sodium，238 nm (13.5-17.0 min) for geniposidic acid，280 nm （17.1-51.0 min）for phellodendrine，salvianolic acid B，345 nm（51.1.1-70.0 min）for palmatine，berberine，336 nm（70.1-78.0 min）for atractylodin and 268 nm(78.1-90.0 min)for tanshinone Ⅱ_A.

Salvianic acid A sodium，geniposidic acid，phellodendrine，salvianolic acid B，palmatine，berberine，atractylodin，tanshinoneⅡ_A had good linearities in their respective linear ranges with all linear correlation coefficients ≥ 0.999 5 and RSDs of the precision，repeatability and stability less than 2.0%. The average recoveries were 101.3%，98.2%，97.3%，98.1%，96.6%，97.9%，98.7%，99.6%，with RSDs lower than 2.0%. The contents of the above eight components in three batches of samples was 4.47-5.51 mg·g^-1，0.93-1.44 mg·g^-1，1.00-1.07 mg·g^-1，5.72-8.67 mg·g^-1，0.64-0.69 mg·g^-1，1.62-1.90 mg·g^-1，0.055-0.088 mg·g^-1，0.29-0.44 mg·g^-1，respectively.

The proposed method is rapid，sensitive and specific，which can be used for determination the contents of eitht components in Shuangshi Tonglin capsules.