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Research progress of brain-computer interface in sleep disorders
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Hao Zhu1, Li Wan2, Shugeng Chen3, *, Mingyong Zhang1, Jie Jia3
Modern Instruments & Medical Treatment | 2025, 31(5) : 9 - 15
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Modern Instruments & Medical Treatment | 2025, 31(5): 9-15
Research progress of brain-computer interface in sleep disorders
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Hao Zhu1, Li Wan2, Shugeng Chen3, *, Mingyong Zhang1, Jie Jia3
Affiliations
  • 1.Department of Rehabilitation Medicine, Luqiao District Hospital of Traditional Chinese Medicine, Taizhou 318050, China
  • 2.Department of Rehabilitation Medicine, Shenzhen Second People's Hospital, Shenzhen 518035, China
  • 3.Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
Published: 2025-10-10 doi: 10.11876/mimt202505002
Outline
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Background

With the accelerating pace of work and life in modern society, sleep disorders have become an increasingly prevalent issue. Brain-computer interface (BCI), as an emerging technological tool, offers new possibilities for the diagnosis and treatment of sleep disorders.

Objective

To analyze and summarize the application of BCI in sleep disorders in recent years and explore its clinical value in the diagnosis and treatment of sleep disorders.

Methods

Literature searches were conducted using the search terms “brain-computer interface”, “electroencephalogram”, “sleep”, “sleep disorders”, “sleep monitoring”, and “sleep intervention” both on the PubMed and China National Knowledge Infrastructure (CNKI) database. The search period spanned from January 2015 to August 2025. The initial search yielded 678 documents. After strict screening and manual addition of 2 more, a total of 34 relevant documents were finally included.

Results

BCI technology is revolutionizing the diagnosis and treatment of sleep disorders by leveraging high-precision EEG signal analysis and intelligent algorithms. Multimodal deep learning models enable BCI systems to achieve high accuracy in sleep-stage classification, while closed-loop auditory, visual, and electrical stimulation systems significantly improve sleep quality. However, core challenges persist, including hardware-side signal noise interference, limited algorithmic generalizability, constraints in device portability, and ethical and privacy concerns, alongside the need for clinical standardization.

Conclusion

Future research should focus on breakthroughs in the synergy of “materials-algorithms-hardware”, enhancing the maturity of multimodal closed-loop intervention systems, establishing standardized clinical validation protocols, and developing robust ethical and safety frameworks. These efforts are expected to advance the further development of BCI technology in the field of sleep disorder research.

Brain-computer interface  /  Sleep disorders  /  Sleep staging  /  Clinical applications
朱皓, 万力, 陈树耿, 章明勇, 贾杰. 脑机接口应用于睡眠障碍的研究进展. 现代仪器与医疗, 2025 , 31 (5) : 9 -15 . DOI: 10.11876/mimt202505002
Hao Zhu, Li Wan, Shugeng Chen, Mingyong Zhang, Jie Jia. Research progress of brain-computer interface in sleep disorders[J]. Modern Instruments & Medical Treatment, 2025 , 31 (5) : 9 -15 . DOI: 10.11876/mimt202505002
Year 2025 volume 31 Issue 5
55
10
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doi: 10.11876/mimt202505002
  • Online Date:2026-10-23
  • Published:2025-10-10
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    1.Department of Rehabilitation Medicine, Luqiao District Hospital of Traditional Chinese Medicine, Taizhou 318050, China
    2.Department of Rehabilitation Medicine, Shenzhen Second People's Hospital, Shenzhen 518035, China
    3.Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
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