Full
Outline
The aim of this study is to provide technical support and reference basis for the research on the mechanism of cerebral small vessel hemorrhage and treatment methods through small animal Magnetic Resonance Imaging (MRI) sequences. This will facilitate in - depth exploration of the nature of the disease, optimization of treatment strategies, and promotion of the development of new treatment methods.
In this study, 5 C57 mice overexpressing the mutant sites of PIK3CA and MAP3K3 (p.I441M) were taken as the research objects. Imaging was carried out using different sequences of 7.0T small - animal nuclear magnetic resonance, such as T1WI, T2WI, SWI, DTI, and ASL. Parameter setting and image acquisition were performed, and the scanning results were statistically analyzed in terms of indicators such as the number of lesions, lesion area, and signal - to - noise ratio.
SWI shows excellent performance in the detection of the number, size, and signal - to - noise ratio of lesions (P<0.05). T2WI shows lesions more clearly than T1WI (P<0.05). DTI and ASL provide micro - structure and blood perfusion information respectively.
The comprehensive application of multiple sequences is helpful for a comprehensive assessment of pathological characteristics
53
10
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
