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Efficacy of transcranial ultrasound stimulation on emotional status in patients with post-stroke dysphagia: a randomized controlled study
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Nian Wang, Jing Yuan, Rongju Ye, Zhilan Liu, Guo Li, Hua Lin*
Modern Instruments & Medical Treatment | 2026, 32(4) : 70 - 75
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Modern Instruments & Medical Treatment | 2026, 32(4): 70-75
Efficacy of transcranial ultrasound stimulation on emotional status in patients with post-stroke dysphagia: a randomized controlled study
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Nian Wang, Jing Yuan, Rongju Ye, Zhilan Liu, Guo Li, Hua Lin*
Affiliations
  • Department of Geriatric Rehabilitation, Shanghai Fourth Rehabilitation Hospital, Shanghai 200040, China
Published: 2026-08-10 doi: 10.11876/mimt202604009
Outline
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Objective

To explore the rehabilitative efficacy of transcranial ultrasound stimulation (TUS) in improving the emotional status of patients with post-stroke dysphagia (PSD).

Methods

A total of 70 inpatients with poststroke dysphagia complicated by mood disorders admitted to our hospital were enrolled from October 2024 to November 2025. Patients were assigned to the control group (shamTUS group) and the observation group (TUS group) by computer-generated simple random sampling at a 1:1 ratio, with 35 patients in each group. The control group received conventional rehabilitation training plus shamTUS intervention, whereas the observation group received conventional rehabilitation training combined with 20-minute daily TUS intervention. Both groups received training 6 days per week. Swallowing function was assessed using the water swallowing test (WST), and emotional status was evaluated using the Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD), and Pittsburgh sleep quality index (PSQI) before and after 4 weeks of treatment.

Results

After treatment, WST grade, HAMA, HAMD, and PSQI scores decreased significantly in both groups compared with baseline (P<0.05). Inter-group comparisons after treatment showed that the WST grade [2 (2, 2) vs. 3(3, 3)], HAMA score [(9.11±3.45) vs. (16.26±4.77)], HAMD score [(8.29±2.81) vs. (15.06±2.54)], and PSQI score [(10.74±1.93) vs. (13.09±2.21)] in the observation group were significantly lower than those in the control group (P<0.05).

Conclusion

TUS combined with conventional rehabilitation training can significantly improve the emotional status of patients with PSD, providing a reference for the comprehensive rehabilitation of patients with PSD and emotional disorders.

Stroke  /  Dysphagia  /  Transcranial ultrasound stimulation  /  Emotional status  /  Rehabilitation training
王年, 袁景, 叶荣菊, 刘智岚, 李果, 林桦. 经颅超声刺激对脑卒中吞咽障碍患者的情绪状况疗效研究. 现代仪器与医疗, 2026 , 32 (4) : 70 -75 . DOI: 10.11876/mimt202604009
Nian Wang, Jing Yuan, Rongju Ye, Zhilan Liu, Guo Li, Hua Lin. Efficacy of transcranial ultrasound stimulation on emotional status in patients with post-stroke dysphagia: a randomized controlled study[J]. Modern Instruments & Medical Treatment, 2026 , 32 (4) : 70 -75 . DOI: 10.11876/mimt202604009
Year 2026 volume 32 Issue 4
95
13
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doi: 10.11876/mimt202604009
  • Receive Date:2026-06-10
  • Online Date:2026-10-23
  • Published:2026-08-10
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  • Received:2026-06-10
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    Department of Geriatric Rehabilitation, Shanghai Fourth Rehabilitation Hospital, Shanghai 200040, China
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红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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