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Outline
To investigate the clinical diagnostic value and safety of endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) in upper gastrointestinal and extramural lesions.
A retrospective analysis was performed on 50 patients who underwent EUS-FNA/B from January 2024 to December 2025. The final comprehensive diagnosis was based on surgical pathology when available, or on follow-up imaging and treatment response in nonsurgical cases. Diagnostic agreement, sensitivity, specificity, predictive values, accuracy, AUC and complications were analyzed.
The final diagnosis included 18 benign and 32 malignant lesions. EUS-FNA/B identified 31 malignant and 19 benign lesions, with 30 true positives, 17 true negatives, 2 false negatives and 1 false positive. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 93.75%, 94.44%, 96.77%, 89.47% and 94.00%, respectively. The AUC was 0.94. No serious complications occurred.
EUS-FNA/B has high diagnostic accuracy and favorable safety for upper gastrointestinal and extramural lesions, and can provide reliable evidence for clinical decision-making.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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