Article(id=1324078502072430608, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202507408, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1753200000000, receivedDateStr=2025-07-23, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793614515082, onlineDateStr=2026-11-02, pubDate=1767974400000, pubDateStr=2026-01-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793614515082, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793614515082, creator=13701087609, updateTime=1793614515082, updator=13701087609, issue=Issue{id=1324078333767594037, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='1', pageStart='1', pageEnd='192', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793614474956, creator='13701087609', updateTime=1793614571752, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324078739914621270, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324078739914621271, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=142, endPage=147, ext={EN=ArticleExt(id=1324078502382809105, articleId=1324078502072430608, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=The chain mediating effects of activities of daily living and depression on self-rated health among empty-nest elderly with chronic disease comorbidity, columnId=1228016572451718132, journalTitle=Modern Preventive Medicine, columnName=Health and Social Behavior, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the mediating role of activities of daily living (ADL) and depression between chronic disease comorbidity and self-rated health in empty-nest elderly, and to provide a reference for improving the self-rated health and quality of life of empty-nest elderly.
Methods A total of 3 542 empty-nest elderly aged 60 years and older from the 2020 China Health and Retirement Longitudinal Study were selected as study subjects. Spearman’s correlation analysis was employed to explore the associations between chronic disease comorbidity, ADL, depression, and self-rated health among empty-nest elderly. The Process 4.1 plugin model 6 in SPSS was used to analyse the mediating effects of ADL and depression on the relationship between chronic disease comorbidity and self-rated health among empty-nest elderly.
Results The direct effect of chronic disease comorbidity on self-rated health among empty-nest elderly individuals was statistically significant (β=-1.2397, 95% CI: -1.4139~-1.0655), the separate mediating effect of ADL was statistically significant (β=-0.159, 95% CI: -0.278~-0.079), the separate mediating effect of depression was statistically significant (β=-0.160, 95% CI: -0.214~-0.115), and the chain mediating effect of ADL and depression was statistically significant (β=-0.073, 95% CI:-0.094~-0.056).
Conclusion Chronic disease comorbidity can directly negatively impact the self-rated health status of empty-nest elderly individuals. It may also influence their self-rated health through the independent or chain mediating effects of activities of ADL and depression. Consequently, it is recommended that policy measures prioritise empty-nest elderly individuals within health interventions to reduce their risk of chronic disease comorbidity. This should involve establishing a comprehensive support system centred on functional assessment and psychological intervention, thereby improving the self-rated health status of this demographic.
, authors=Xin SUI, Wen-chao WANG, Yun-na GONG, Yun-long JIAN, Li-qin SONG, Xiao-lin ZHANG, Yong MA, authorsList=Xin SUI, Wen-chao WANG, Yun-na GONG, Yun-long JIAN, Li-qin SONG, Xiao-lin ZHANG, Yong MA, authorCompany=null, correspAuthors=Yong MA, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324078505482399770, articleId=1324078502072430608, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=日常生活活动能力和抑郁在慢性病共病对空巢老人自评健康的链式中介效应, columnId=1228016572640461823, journalTitle=现代预防医学, columnName=健康与社会行为, runingTitle=null, highlight=null, articleAbstract=
目的 探讨日常生活活动能力(activities of daily living,ADL)和抑郁在慢性病共病和空巢老人自评健康间的中介作用。为改善空巢老人自评健康状况,提高其生活质量提供参考。
方法 选取2020年中国健康与养老追踪调查中3 542例≥60岁的空巢老人作为研究对象,运用Spearman相关分析法探究慢性病共病、ADL、抑郁和空巢老人自评健康的相关性,使用SPSS中Process 4.1插件模型6分析ADL、抑郁在慢性病共病和空巢老人自评健康间的中介作用。
结果 慢性病共病对空巢老人自评健康的直接效应具有统计学意义(β=-1.240,95% CI:-1.414~-1.066),ADL的单独中介效应具有统计学意义(β=-0.159,95% CI:-0.278~-0.079),抑郁的单独中介效应具有统计学意义(β=-0.160,95% CI:-0.214~-0.115),ADL和抑郁的链式中介效应具有统计学意义(β=-0.073,95% CI:-0.094~-0.056)。
结论 慢性病共病可以直接负向影响空巢老人自评健康状况,还可以通过ADL和抑郁的单独或链式中介作用影响空巢老人自评健康情况。因此,建议政策层面将空巢老人纳入健康干预的优先序列,降低患慢性病共病风险,构建以功能评估与心理干预为核心的综合支持体系,进而改善空巢老人自评健康状况。
, authors=隋欣, 王文超, 宫云娜, 菅云龙, 宋立芹, 张晓林, 马勇, authorsList=隋欣, 王文超, 宫云娜, 菅云龙, 宋立芹, 张晓林, 马勇, authorCompany=null, correspAuthors=马勇, authorNote=
隋欣(2000—),女,硕士在读,研究方向:行政管理
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=p7rPJybTQpEZzNaN3l0+sQ==, magXml=a69Jnn/nLkk3OvMtcHz1Gw==, pdfUrl=null, pdf=GY4zr/fy3sI1LZjvSgWYDg==, pdfFileSize=675467, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=anYdvevW1PqOtK59CjMMhg==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=a/EYILwe0gBmbR8wm1/WQg==, mapNumber=null, fund=null)}, authors=[Author(id=1324078505864081439, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1324078505952161825, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, authorId=1324078505864081439, language=EN, stringName=Xin SUI, firstName=Xin, middleName=null, lastName=SUI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Management, Shandong Second Medical University, Weifang, Shandong 261053, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1324078506027659298, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, authorId=1324078505864081439, language=CN, stringName=隋欣, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=山东第二医科大学管理学院,山东 潍坊 261053, bio={"content":"
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12: 1393530., articleTitle=The mediating effect of Life satisfaction between daily living abilities and depressive symptoms in the Chinese older People: evidence from CHARLS 2020, refAbstract=null)], funds=[Fund(id=1324078511287316567, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, awardId=20CFX017, language=CN, fundingSource=国家社会科学基金项目(20CFX017), fundOrder=null, country=null), Fund(id=1324078511350231128, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, awardId=21YJC820050, language=CN, fundingSource=教育部人文社会科学基金项目(21YJC820050), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1324078505750835227, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, xref=null, ext=[AuthorCompanyExt(id=1324078505759223836, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, companyId=1324078505750835227, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Management, Shandong Second Medical University, Weifang, Shandong 261053, China), AuthorCompanyExt(id=1324078505784389661, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, companyId=1324078505750835227, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=山东第二医科大学管理学院,山东 潍坊 261053)])], figs=[ArticleFig(id=1324078510024831051, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=EN, label=Figure 1, caption=
Chain mediation model of ADL and depression in the relationship between chronic disease comorbidity and self-rated health among empty-nest elderly, figureFileSmall=pm83tbka3t4JLoDOhnKpow==, figureFileBig=anYdvevW1PqOtK59CjMMhg==, tableContent=null), ArticleFig(id=1324078510125494348, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=CN, label=图1, caption=
ADL和抑郁在慢性病共病与空巢老人自评健康的链式中介模型图, figureFileSmall=pm83tbka3t4JLoDOhnKpow==, figureFileBig=anYdvevW1PqOtK59CjMMhg==, tableContent=null), ArticleFig(id=1324078510305849421, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=EN, label=Table 1, caption=
Assignment of values to variables
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 赋值 |
|---|
| 性别 | 男=1,女=2 |
| 年龄(岁) | 60~64=1,65~69=2,70~74=3,≥75=4 |
| 婚姻状况 | 有配偶=1,无配偶=0 |
| 是否有养老保险 | 是=1,否=0 |
| 是否有医疗保险 | 是=1,否=0 |
| 是否上网 | 上网=1,不上网=0 |
| 是否吸烟 | 吸烟=1,不吸烟=0 |
| 是否饮酒 | 饮酒=1,不饮酒=0 |
), ArticleFig(id=1324078510461038670, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=CN, label=表1, caption=
各变量赋值情况
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 赋值 |
|---|
| 性别 | 男=1,女=2 |
| 年龄(岁) | 60~64=1,65~69=2,70~74=3,≥75=4 |
| 婚姻状况 | 有配偶=1,无配偶=0 |
| 是否有养老保险 | 是=1,否=0 |
| 是否有医疗保险 | 是=1,否=0 |
| 是否上网 | 上网=1,不上网=0 |
| 是否吸烟 | 吸烟=1,不吸烟=0 |
| 是否饮酒 | 饮酒=1,不饮酒=0 |
), ArticleFig(id=1324078510549119055, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=EN, label=Table 2, caption=
Basic demographic information of 3 542 empty-nest elderly [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 项目 | 分组 | 健康状况 | χ2值 | P值 |
|---|
| 不健康(n=2 770) | 健康(n=772) |
|---|
| 性别 | 男性 | 1 452(66.7) | 440(23.3) | 5.081 | 0.024 |
| 女性 | 1 318(79.9) | 332(20.1) | | |
| 年龄(岁) | 60~64 | 834(76.4) | 257(23.6) | 4.140 | 0.247 |
| 65~69 | 887(79.6) | 228(20.4) | | |
| 70~74 | 574(79.5) | 148(20.5) | | |
| ≥75 | 475(77.4) | 139(22.6) | | |
| 婚姻状况 | 有配偶 | 2 317(78.3) | 641(21.7) | 0.166 | 0.684 |
| 无配偶 | 453(77.6) | 131(22.4) | | |
| 养老保险 | 是 | 2 387(78.5) | 654(21.5) | 1.057 | 0.304 |
| 否 | 383(76.4) | 118(23.6) | | |
| 医疗保险 | 是 | 2 630(78.3) | 730(21.7) | 0.185 | 0.667 |
| 否 | 140(76.9) | 42(23.1) | | |
| 是否上网 | 上网 | 578(75.5) | 188(24.5) | 4.328 | 0.037 |
| 不上网 | 2 192(79.0) | 584(21.0) | | |
| 是否吸烟 | 吸烟 | 1 321(77.2) | 391(22.8) | 2.116 | 0.146 |
| 不吸烟 | 1 449(79.2) | 381(20.8) | | |
| 是否饮酒 | 饮酒 | 914(73.5) | 330(26.5) | 25.186 | <0.001 |
| 不饮酒 | 1 856(80.8) | 442(19.2) | | |
), ArticleFig(id=1324078510637199440, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=CN, label=表2, caption=
3 542名空巢老人的基本人口学信息[n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 项目 | 分组 | 健康状况 | χ2值 | P值 |
|---|
| 不健康(n=2 770) | 健康(n=772) |
|---|
| 性别 | 男性 | 1 452(66.7) | 440(23.3) | 5.081 | 0.024 |
| 女性 | 1 318(79.9) | 332(20.1) | | |
| 年龄(岁) | 60~64 | 834(76.4) | 257(23.6) | 4.140 | 0.247 |
| 65~69 | 887(79.6) | 228(20.4) | | |
| 70~74 | 574(79.5) | 148(20.5) | | |
| ≥75 | 475(77.4) | 139(22.6) | | |
| 婚姻状况 | 有配偶 | 2 317(78.3) | 641(21.7) | 0.166 | 0.684 |
| 无配偶 | 453(77.6) | 131(22.4) | | |
| 养老保险 | 是 | 2 387(78.5) | 654(21.5) | 1.057 | 0.304 |
| 否 | 383(76.4) | 118(23.6) | | |
| 医疗保险 | 是 | 2 630(78.3) | 730(21.7) | 0.185 | 0.667 |
| 否 | 140(76.9) | 42(23.1) | | |
| 是否上网 | 上网 | 578(75.5) | 188(24.5) | 4.328 | 0.037 |
| 不上网 | 2 192(79.0) | 584(21.0) | | |
| 是否吸烟 | 吸烟 | 1 321(77.2) | 391(22.8) | 2.116 | 0.146 |
| 不吸烟 | 1 449(79.2) | 381(20.8) | | |
| 是否饮酒 | 饮酒 | 914(73.5) | 330(26.5) | 25.186 | <0.001 |
| 不饮酒 | 1 856(80.8) | 442(19.2) | | |
), ArticleFig(id=1324078510712696913, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=EN, label=Table 3, caption=
Correlation analysis results (r)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 慢性病共病 | ADL | 抑郁得分 | 自评健康 |
|---|
| 共病 | 1 | — | — | — |
| ADL | -0.229*** | 1 | — | |
| 抑郁得分 | 0.194*** | -0.395*** | 1 | — |
| 自评健康 | -0.302*** | 0.228*** | -0.265*** | 1 |
), ArticleFig(id=1324078510796582994, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=CN, label=表3, caption=
相关分析结果(r)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 慢性病共病 | ADL | 抑郁得分 | 自评健康 |
|---|
| 共病 | 1 | — | — | — |
| ADL | -0.229*** | 1 | — | |
| 抑郁得分 | 0.194*** | -0.395*** | 1 | — |
| 自评健康 | -0.302*** | 0.228*** | -0.265*** | 1 |
), ArticleFig(id=1324078510876274771, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=EN, label=Table 4, caption=
Results of regression analyses of the chain mediation model
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 模型1:ADL | 模型2:抑郁 | 模型3:自评健康 |
|---|
| β |  | t值 | β |  | t值 | β |  | t值 |
|---|
| 常量 | 37.221 | 0.338 | 110.233*** | 22.539 | 1.097 | 20.551*** | -4.226 | 0.971 | -4.353*** |
| 共病 | -1.341 | 0.136 | -9.843*** | 1.703 | 0.213 | 7.998*** | -1.240 | 0.089 | -13.949*** |
| ADL | | | | -0.582 | 0.026 | -22.441*** | 0.118 | 0.026 | 4.590*** |
| 抑郁 | | | | | | | -0.094 | 0.009 | -10.523*** |
| 年龄 | -0.411 | 0.062 | -6.671*** | -0.136 | 0.096 | -1.424 | 0.032 | 0.043 | 0.745 |
| 婚姻 | 0.075 | 0.179 | 0.420 | 1.694 | 0.276 | 6.136*** | 0.119 | 0.124 | 1.518 |
| 性别 | -0.467 | 0.190 | -2.464** | 2.193 | 0.293 | 7.489*** | 0.231 | 0.133 | 1.732 |
| 吸烟 | 0.251 | 0.182 | 1.378 | -0.282 | 0.281 | -1.005 | 0.010 | 0.125 | 0.077 |
| 饮酒 | -0.590 | 0.148 | -4.000*** | 0.580 | 0.228 | 2.543** | -0.240 | 0.100 | -2.403** |
), ArticleFig(id=1324078510976938068, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=CN, label=表4, caption=
链式中介模型回归分析结果
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 模型1:ADL | 模型2:抑郁 | 模型3:自评健康 |
|---|
| β |  | t值 | β |  | t值 | β |  | t值 |
|---|
| 常量 | 37.221 | 0.338 | 110.233*** | 22.539 | 1.097 | 20.551*** | -4.226 | 0.971 | -4.353*** |
| 共病 | -1.341 | 0.136 | -9.843*** | 1.703 | 0.213 | 7.998*** | -1.240 | 0.089 | -13.949*** |
| ADL | | | | -0.582 | 0.026 | -22.441*** | 0.118 | 0.026 | 4.590*** |
| 抑郁 | | | | | | | -0.094 | 0.009 | -10.523*** |
| 年龄 | -0.411 | 0.062 | -6.671*** | -0.136 | 0.096 | -1.424 | 0.032 | 0.043 | 0.745 |
| 婚姻 | 0.075 | 0.179 | 0.420 | 1.694 | 0.276 | 6.136*** | 0.119 | 0.124 | 1.518 |
| 性别 | -0.467 | 0.190 | -2.464** | 2.193 | 0.293 | 7.489*** | 0.231 | 0.133 | 1.732 |
| 吸烟 | 0.251 | 0.182 | 1.378 | -0.282 | 0.281 | -1.005 | 0.010 | 0.125 | 0.077 |
| 饮酒 | -0.590 | 0.148 | -4.000*** | 0.580 | 0.228 | 2.543** | -0.240 | 0.100 | -2.403** |
), ArticleFig(id=1324078511065018453, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=EN, label=Table 5, caption=
Test of chain mediation effects
, figureFileSmall=null, figureFileBig=null, tableContent=
| 路径 | 效应值(95%CI) | Boot SE |
|---|
| 直接效应 | -1.240(-1.414~-1.066) | 0.089 |
| 总间接效应 | -0.392(-0.524~-0.296) | 0.057 |
| 路径1 | -0.159(-0.278~-0.079) | 0.051 |
| 路径2 | -0.160(-0.214~-0.115) | 0.025 |
| 路径3 | -0.073(-0.094~-0.056) | 0.010 |
), ArticleFig(id=1324078511140515926, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078502072430608, language=CN, label=表5, caption=
链式中介效应检验
, figureFileSmall=null, figureFileBig=null, tableContent=
| 路径 | 效应值(95%CI) | Boot SE |
|---|
| 直接效应 | -1.240(-1.414~-1.066) | 0.089 |
| 总间接效应 | -0.392(-0.524~-0.296) | 0.057 |
| 路径1 | -0.159(-0.278~-0.079) | 0.051 |
| 路径2 | -0.160(-0.214~-0.115) | 0.025 |
| 路径3 | -0.073(-0.094~-0.056) | 0.010 |
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