Article(id=1324078351090069667, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202409512, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1727539200000, receivedDateStr=2024-09-29, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793614479086, onlineDateStr=2026-11-02, pubDate=1767974400000, pubDateStr=2026-01-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793614479086, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793614479086, creator=13701087609, updateTime=1793614479086, updator=13701087609, issue=Issue{id=1324078333767594037, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='1', pageStart='1', pageEnd='192', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793614474956, creator='13701087609', updateTime=1793614571752, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324078739914621270, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324078739914621271, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=32, endPage=38, ext={EN=ArticleExt(id=1324078351555637412, articleId=1324078351090069667, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Trends in the burden of hypertensive heart disease attributed to high BMI in China and globally from 1990 to 2021, columnId=1240413921954295836, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the current status and trends of hypertensive heart disease burden attributable to high BMI in China and globally from 1990 to 2021, in order to provide data support for the development of obesity and cardiovascular disease prevention and control strategies in China and worldwide.
Methods Data on disability-adjusted life years (DALYs) and deaths from hypertensive heart disease attributable to high BMI were extracted from the 2021 Global Burden of Disease database. The total DALYs and number of deaths caused by high BMI-related hypertensive heart disease in China and globally in 2021, as well as the age-standardized mortality rate and trends from 1990 to 2021, were described. The Joinpoint regression model was used to calculate the average annual percentage change (AAPC) in age-standardized DALY and mortality rates from 1990 to 2021 in both China and globally.
Results In 2021, the age-standardized mortality rate attributable to high BMI-related hypertension heart disease in China was 6.90 per 100 000 (AAPC=-1.09, P<0.001), and the age-standardized DALY rate was 120.03 per 100 000 (AAPC=-1.41, P<0.001), both showing a downward trend. Globally, the age-standardized mortality rate was 7.21 per 100 000 (AAPC=0.19, P<0.001), and the age-standardized DALY rate was 147.34 per 100 000 (AAPC=0.07),showing a slow upward trend.
Conclusion From 1990 to 2021, the age-standardized mortality rate and DALY rate for hypertensive heart disease attributable to high BMI in China showed a downward trend, contrary to the global trend. However,the burden was heavier among women and the elderly. Therefore, it is crucial to emphasize obesity prevention and control strategies for the elderly, promote healthy lifestyle habits, and adopt targeted interventions to reduce the disease burden.
, authors=Li MA
1, Peng-yao LI
1, Qian-kun LIU
2, Ju-ju HUANG
1, Jia-xue PANG
1, Yang XU
1, Hui XIE
1, authorsList=Li MA, Peng-yao LI, Qian-kun LIU, Ju-ju HUANG, Jia-xue PANG, Yang XU, Hui XIE, authorCompany=null, correspAuthors=Hui XIE, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324078354244186285, articleId=1324078351090069667, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=1990—2021年中国和全球归因于高BMI的高血压性心脏病疾病负担变化趋势分析, columnId=1228016567632462653, journalTitle=现代预防医学, columnName=流行病与统计方法, runingTitle=null, highlight=null, articleAbstract=
目的 分析1990—2021年中国和全球归因于高身体质量指数(body mass index,BMI)的高血压性心脏病疾病负担现状与趋势,以期为中国和全球制定肥胖与心血管疾病的防控策略提供数据支持。
方法 基于2021年全球疾病负担研究数据库,提取了高BMI相关高血压性心脏病伤残调整生命年(disability-adjusted life year,DALY)和死亡数据,描述2021年中国和全球高BMI导致的高血压性心脏病DALY、死亡总数、年龄标化死亡率以及1990—2021年的变化趋势,并采用joinpoint回归模型计算中国和全球1990—2021年标化DALY率和死亡率的平均年度变化百分比(average annual percentage change,AAPC)。
结果 2021年中国归因于高BMI的高血压性心脏病标化死亡率为6.90/10万(AAPC=-1.09,P<0.001)、标化DALYs率为 120.03/10万(AAPC=-1.41,P<0.001),呈现下降趋势;而全球标化死亡率为7.21/10万(AAPC=0.19,P<0.001)、标化DALYs率为 147.34/10万(AAPC=0.07),呈缓慢上升趋势。
结论 1990—2021年中国归因于高BMI的高血压性心脏病标化死亡率、标化DALYs率均呈下降趋势,与全球的发展趋势相反;但女性和老年人群负担较重,因此仍需重视老年人的肥胖防控策略,加强宣传健康的生活模式,采取针对性措施和有效干预以减轻其疾病负担。
, authors=马丽
1, 李鹏鹞
1, 刘乾坤
2, 黄菊菊
1, 庞佳雪
1, 徐洋
1, 谢晖
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马丽(1999—),女,硕士在读,研究方向:社区护理,老年医学
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=eFYsx/L0Yay+5JcKz6pYIA==, magXml=WeVrT1EypK9T7Co7b9Bw2g==, pdfUrl=null, pdf=+Bo8rWzW04pt5MYlPi+MTQ==, pdfFileSize=1088222, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=hTU5pZ88KbZcvqjnab8ckA==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=BTmVXIH5Vp6RFUC6WHMeUQ==, mapNumber=null, fund=null)}, authors=[Author(id=1324078354676199604, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1324078354764279990, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, authorId=1324078354676199604, language=EN, stringName=Li MA, firstName=Li, middleName=null, lastName=MA, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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Lin H,
Xia SL. Analysis on death of cardiovascular disease and potential years of Life lost in Zhongshan city from 2014 to 2019[J].
Modern Preventive Medicine,
2021,
48(14): 2528-2531, 2557. (In Chinese), articleTitle=Analysis on death of cardiovascular disease and potential years of Life lost in Zhongshan city from 2014 to 2019, refAbstract=null)], funds=[Fund(id=1324078360338510058, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, awardId=202410367062, language=CN, fundingSource=国家级大学生创新创业训练计划(202410367062), fundOrder=null, country=null), Fund(id=1324078360418201835, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, awardId=LH250201002, language=CN, fundingSource=蚌埠医科大学龙湖英才项目(LH250201002), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1324078354474873006, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, xref=1., ext=[AuthorCompanyExt(id=1324078354483261615, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, companyId=1324078354474873006, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Nursing, Bengbu Medical University, Bengbu, Anhui 233030, China), AuthorCompanyExt(id=1324078354495844528, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, companyId=1324078354474873006, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.蚌埠医医科大学护理学院,安徽 蚌埠 233030)]), AuthorCompany(id=1324078354600702129, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, xref=2., ext=[AuthorCompanyExt(id=1324078354604896434, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, companyId=1324078354600702129, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.蚌埠市第一人民医院,安徽 蚌埠 233030)])], figs=[ArticleFig(id=1324078358887280862, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=EN, label=Figure 1, caption=
Temporal trends in hypertensive heart disease burden attributable to high BMI in China and globally from 1990 to 2021, figureFileSmall=BBnE+0DmGvtvquvYXOOVxw==, figureFileBig=hTU5pZ88KbZcvqjnab8ckA==, tableContent=null), ArticleFig(id=1324078358946001119, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=CN, label=图1, caption=
1990—2021年中国和全球归因于高BMI的高血压性心脏病疾病负担的趋势注:A为中国;B为全球。
, figureFileSmall=BBnE+0DmGvtvquvYXOOVxw==, figureFileBig=hTU5pZ88KbZcvqjnab8ckA==, tableContent=null), ArticleFig(id=1324078359126356192, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=EN, label=Figure 2, caption=
Sex-specific disease burden of hypertensive heart disease attributable to high BMI in China from 1990 to 2021, figureFileSmall=TM7XB82n4Nm/3ilxIHhprA==, figureFileBig=Z73IXfXgBmwm4FG88va1IA==, tableContent=null), ArticleFig(id=1324078359323488481, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=CN, label=图2, caption=
1990—2021年中国不同性别人群归因于高BMI的高血压性心脏病疾病负担注:A为1990年中国死亡数据;B为1990年中国DALYs数据;C为2021年中国死亡数据;D为 2021年中国DALYs数据。
, figureFileSmall=TM7XB82n4Nm/3ilxIHhprA==, figureFileBig=Z73IXfXgBmwm4FG88va1IA==, tableContent=null), ArticleFig(id=1324078359449317602, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=EN, label=Figure 3, caption=
Sex-specific disease burden of hypertensive heart disease attributable to high BMI globally from 1990 to 2021, figureFileSmall=4COR7pihS4maZK+uRHl9uA==, figureFileBig=rnUvcCqzH5PqlF277mzS2w==, tableContent=null), ArticleFig(id=1324078359747113187, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=CN, label=图3, caption=
1990—2021年全球不同性别人群归因于高BMI的高血压性心脏病疾病负担注:A为1990年全球死亡数据;B为1990年全球DALYs数据;C为2021年全球死亡数据;D为2021年全球DALYs数据。
, figureFileSmall=4COR7pihS4maZK+uRHl9uA==, figureFileBig=rnUvcCqzH5PqlF277mzS2w==, tableContent=null), ArticleFig(id=1324078359810027748, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=EN, label=Figure 4, caption=
Joinpoint regression analysis of disease burden metrics attributable to high BMI for hypertensive heart disease in China and globally from 1990 to 2021, figureFileSmall=vQTAGhj4w/bEMJxAR7S83g==, figureFileBig=jSHt0mlxNkqTaTAhlWCnhQ==, tableContent=null), ArticleFig(id=1324078359885525221, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=CN, label=图4, caption=
1990—2021年中国和全球归因于高BMI的高血压性心脏病疾病负担指标joinpoint回归注:A为中国标化死亡率;B为中国标化DALYs率;C为全球标化死亡率;D为全球标化DALYs率。
, figureFileSmall=vQTAGhj4w/bEMJxAR7S83g==, figureFileBig=jSHt0mlxNkqTaTAhlWCnhQ==, tableContent=null), ArticleFig(id=1324078359952634086, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=EN, label=Table 1, caption=
Disease burden attributable to high BMI for hypertensive heart disease and its temporal trends in China and globally from 1990 to 2021(95% CI)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 地区 | 分类 | 1990年 | 2021年 | 1990—2021年 AAPC | P值 |
|---|
| 全年龄段病例数 | 标化率(1/10万) | 全年龄段病例数 | 标化率(1/10万) |
|---|
| 中国 | 死亡 | 58 894 (82 600~33 794) | 9.66 (4.72~14.65) | 124 764 (63 334~198 271) | 6.90 (3.14~11.62) | -1.09 (-1.22~0.96) | <0.001 |
| DALYs | 1 393 488 (812 664~1 929 010) | 182.57 (104.75~260.36) | 2 373 040 (1 485 461~3 462 005) | 120.03 (71.90~180.13) | -1.41 (-1.58~1.24) | <0.001 |
| 全球 | 死亡 | 240 096 (16 8851~313 374) | 6.83 (4.37~9.32) | 594 899 (36 292~804 914) | 7.21 (4.23~9.94) | 0.19 (0.08 ~ 0.31) | <0.001 |
| DALYs | 5 666 017 (4 251 059~7 069 738) | 144.72 (106.22~182.76) | 12 551 752 (9 489 124~15 451 016) | 147.34 (109.06~183.45) | 0.07 (-0.04~0.18) | 0.207 |
), ArticleFig(id=1324078360036520167, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=CN, label=表1, caption=
1990—2021年中国和全球归因于高BMI的高血压性心脏病疾病负担及其变化趋势(95% CI)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 地区 | 分类 | 1990年 | 2021年 | 1990—2021年 AAPC | P值 |
|---|
| 全年龄段病例数 | 标化率(1/10万) | 全年龄段病例数 | 标化率(1/10万) |
|---|
| 中国 | 死亡 | 58 894 (82 600~33 794) | 9.66 (4.72~14.65) | 124 764 (63 334~198 271) | 6.90 (3.14~11.62) | -1.09 (-1.22~0.96) | <0.001 |
| DALYs | 1 393 488 (812 664~1 929 010) | 182.57 (104.75~260.36) | 2 373 040 (1 485 461~3 462 005) | 120.03 (71.90~180.13) | -1.41 (-1.58~1.24) | <0.001 |
| 全球 | 死亡 | 240 096 (16 8851~313 374) | 6.83 (4.37~9.32) | 594 899 (36 292~804 914) | 7.21 (4.23~9.94) | 0.19 (0.08 ~ 0.31) | <0.001 |
| DALYs | 5 666 017 (4 251 059~7 069 738) | 144.72 (106.22~182.76) | 12 551 752 (9 489 124~15 451 016) | 147.34 (109.06~183.45) | 0.07 (-0.04~0.18) | 0.207 |
), ArticleFig(id=1324078360112017640, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=EN, label=Table 2, caption=
Joinpoint regression analysis of disease burden metrics attributable to high BMI for hypertensive heart disease in China and globally from 1990 to 2021
, figureFileSmall=null, figureFileBig=null, tableContent=
| 地区 | 分类 | 指标 | 时间(年) | 变化值(%) | 95%CI | t值 | P值 |
|---|
| 中国 | 标化死亡率 | APC | 1990—1992 | -1.36 | -2.44~-0.27 | -2.65 | 0.018 |
| | | 1992—2001 | -2.90 | -3.02~-2.78 | -51.94 | <0.001 |
| | | 2001—2006 | -4.93 | -5.27~-4.59 | -29.79 | <0.001 |
| | | 2006—2010 | 2.71 | 2.13~3.29 | 10.09 | <0.001 |
| | | 2010—2016 | 1.52 | 1.24~1.79 | 11.76 | <0.001 |
| | | 2016—2021 | 0.15 | -0.14~0.44 | 1.13 | 0.278 |
| | AAPC | 1990—2021 | -1.09 | -1.22~-0.96 | -16.54 | <0.001 |
| 标化DALYs率 | APC | 1990—2000 | -3.05 | -3.26~-2.84 | -30.01 | <0.001 |
| | | 2000—2006 | -4.84 | -5.39~-4.28 | -17.69 | <0.001 |
| | | 2006—2015 | 1.75 | 1.45~2.05 | 12.12 | <0.001 |
| | | 2015—2021 | 0.18 | -0.34~0.70 | 0.73 | 0.474 |
| | AAPC | 1990—2021 | -1.41 | -1.58~-1.24 | -15.78 | <0.001 |
| 全球 | 标化死亡率 | APC | 1990—1998 | -0.35 | -0.47~-0.24 | -6.26 | <0.001 |
| | | 1998—2002 | 0.84 | 0.28~1.39 | 3.18 | 0.005 |
| | | 2002—2006 | -0.19 | -0.75~0.37 | -0.71 | 0.485 |
| | | 2006—2017 | 0.75 | 0.66~0.84 | 17.16 | <0.001 |
| | | 2017—2021 | -0.47 | -0.84~-0.09 | -2.62 | 0.017 |
| | AAPC | 1990—2021 | 0.19 | 0.08~0.31 | 3.40 | <0.001 |
| 标化DALYs率 | APC | 1990—1994 | -0.15 | -0.43~0.13 | -1.17 | 0.262 |
| | | 1994—1998 | -0.66 | -1.07~-0.24 | -3.35 | 0.004 |
| | | 1998—2002 | 0.59 | 0.17~1.02 | 2.98 | 0.009 |
| | | 2002—2006 | -0.37 | -0.79~0.06 | -1.86 | 0.083 |
| | | 2006—2019 | 0.49 | 0.45~0.54 | 21.28 | <0.001 |
| | | 2019—2021 | -0.96 | -1.81~-0.11 | -2.39 | 0.030 |
| | AAPC | 1990—2021 | 0.07 | -0.04~0.18 | 1.26 | 0.207 |
), ArticleFig(id=1324078360195903721, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078351090069667, language=CN, label=表2, caption=
1990—2021年中国和全球归因于高BMI的高血压性心脏病疾病负担指标joinpoint回归
, figureFileSmall=null, figureFileBig=null, tableContent=
| 地区 | 分类 | 指标 | 时间(年) | 变化值(%) | 95%CI | t值 | P值 |
|---|
| 中国 | 标化死亡率 | APC | 1990—1992 | -1.36 | -2.44~-0.27 | -2.65 | 0.018 |
| | | 1992—2001 | -2.90 | -3.02~-2.78 | -51.94 | <0.001 |
| | | 2001—2006 | -4.93 | -5.27~-4.59 | -29.79 | <0.001 |
| | | 2006—2010 | 2.71 | 2.13~3.29 | 10.09 | <0.001 |
| | | 2010—2016 | 1.52 | 1.24~1.79 | 11.76 | <0.001 |
| | | 2016—2021 | 0.15 | -0.14~0.44 | 1.13 | 0.278 |
| | AAPC | 1990—2021 | -1.09 | -1.22~-0.96 | -16.54 | <0.001 |
| 标化DALYs率 | APC | 1990—2000 | -3.05 | -3.26~-2.84 | -30.01 | <0.001 |
| | | 2000—2006 | -4.84 | -5.39~-4.28 | -17.69 | <0.001 |
| | | 2006—2015 | 1.75 | 1.45~2.05 | 12.12 | <0.001 |
| | | 2015—2021 | 0.18 | -0.34~0.70 | 0.73 | 0.474 |
| | AAPC | 1990—2021 | -1.41 | -1.58~-1.24 | -15.78 | <0.001 |
| 全球 | 标化死亡率 | APC | 1990—1998 | -0.35 | -0.47~-0.24 | -6.26 | <0.001 |
| | | 1998—2002 | 0.84 | 0.28~1.39 | 3.18 | 0.005 |
| | | 2002—2006 | -0.19 | -0.75~0.37 | -0.71 | 0.485 |
| | | 2006—2017 | 0.75 | 0.66~0.84 | 17.16 | <0.001 |
| | | 2017—2021 | -0.47 | -0.84~-0.09 | -2.62 | 0.017 |
| | AAPC | 1990—2021 | 0.19 | 0.08~0.31 | 3.40 | <0.001 |
| 标化DALYs率 | APC | 1990—1994 | -0.15 | -0.43~0.13 | -1.17 | 0.262 |
| | | 1994—1998 | -0.66 | -1.07~-0.24 | -3.35 | 0.004 |
| | | 1998—2002 | 0.59 | 0.17~1.02 | 2.98 | 0.009 |
| | | 2002—2006 | -0.37 | -0.79~0.06 | -1.86 | 0.083 |
| | | 2006—2019 | 0.49 | 0.45~0.54 | 21.28 | <0.001 |
| | | 2019—2021 | -0.96 | -1.81~-0.11 | -2.39 | 0.030 |
| | AAPC | 1990—2021 | 0.07 | -0.04~0.18 | 1.26 | 0.207 |
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