Article(id=1324078335990575158, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202508254, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1755360000000, receivedDateStr=2025-08-17, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793614475486, onlineDateStr=2026-11-02, pubDate=1767974400000, pubDateStr=2026-01-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793614475486, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793614475486, creator=13701087609, updateTime=1793614475486, updator=13701087609, issue=Issue{id=1324078333767594037, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='1', pageStart='1', pageEnd='192', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793614474956, creator='13701087609', updateTime=1793614571752, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324078739914621270, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324078739914621271, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078333767594037, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=13, endPage=19, ext={EN=ArticleExt(id=1324078336217067575, articleId=1324078335990575158, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Multimorbidity of common chronic non-communicable diseases and its influencing factors among male detoxification addicts under compulsory isolation in Yunnan Province, columnId=1240413921954295836, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods, runingTitle=null, highlight=null, articleAbstract=
Objective The aim of this study was to analyze the prevalence of multimorbidity of five chronic non-communicable diseases (hypertension, diabetes, coronary heart disease, stroke, and chronic obstructive pulmonary disease) and its influencing factors among male detoxification addicts under compulsory isolations in Yunnan Province.
Methods The multistage random cluster sampling method was adopted to select 1 021 male detoxification addicts under compulsory isolation from compulsory detoxification centers in Yunnan Province, and each participant received on-site questionnaire surveys and physical examinations. The Structure Equation Modeling (SEM) was used to analyze the influencing factors of multimorbidity of five chronic non-communicable diseases (NCDs).
Results Among the study population, the prevalence of individuals who suffered from chronic NCDs mutimorbidity was 6.6%. The results of the SEM analysis indicated that age, sleep quality, and self-rated health status had both direct and indirect effects on mutimorbidity of chronic NCDs, with standardized total effects of 0.474(95% CI: 0.290-0.680), 0.257 (95% CI: 0.076-0.486), and 0.293 (95% CI: 0.130-0.483), respectively. Age had an indirect effect through mental health and self-rated health on chronic NCDs mutimorbidity, with standardized indirect effects of 0.046(95% CI: 0.016-0.095), and 0.066 (95% CI: 0.033-0.103), respectively. Sleep quality had an indirect effect through mental health and self-rated health, with standardized indirect effects of 0.043 (95% CI: 0.018-0.081), and 0.033 (95% CI: 0.015-0.058), respectively. Self-rated health status had an indirect effect through mental health, with standardized indirect effects of 0.073 (95% CI: 0.033-0.138). Mental health and central obesity had direct effect on chronic NCDs mutimorbidity, with standardized direct effects of 0.229 (95% CI: 0.111-0.348), 0.198 (95% CI: 0.085-0.310), respectively.
Conclusion The findings suggest future measures to strengthen the prevention, control, and management of chronic NCDs should focus more on male detoxification addicts who are older and have poor sleep quality, poor mental health, central obesity, and poor self-rated health, to reduce the risk of NCD multimorbidity.
, authors=Xi-min LI
1, 2, Chun-yi RUAN
1, 2, Rui-min SHI
1, 2, Qing-rou BAO
1, 2, Fan GU
1, 2, Li CHEN
1, 2, Le CAI
1, 2, authorsList=Xi-min LI, Chun-yi RUAN, Rui-min SHI, Qing-rou BAO, Fan GU, Li CHEN, Le CAI, authorCompany=null, correspAuthors=Le CAI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324078336795881530, articleId=1324078335990575158, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=云南省男性强制戒毒人员常见慢性病共病现状及影响因素研究, columnId=1228016567632462653, journalTitle=现代预防医学, columnName=流行病与统计方法, runingTitle=null, highlight=null, articleAbstract=
目的 分析云南省男性强制戒毒人员五种慢性病(高血压、糖尿病、冠心病、脑卒中和慢性阻塞性肺病)共病现状及影响因素。
方法 采用多阶段随机整群抽样的方式,抽取云南省1 021名男性戒毒人员进行现场问卷调查和体格检查,并运用结构方程模型(structure equation modeling, SEM)分析五种慢性病共病的影响因素。
结果 调查人群慢性病共病率为6.6%。SEM分析结果显示,年龄、睡眠质量和自评健康状况均会对慢性病共病产生直接和间接效应,其标准化总效应分别为0.474(95% CI:0.290~0.680)、0.257(95% CI:0.076~0.486)和0.293(95% CI:0.130~0.483);其中年龄通过心理健康问题和自评健康状况产生间接效应,其标准化间接效应分别为0.046(95% CI:0.016~0.095)、0.066(95% CI:0.033~0.103);睡眠质量通过心理健康问题和自评健康状况产生间接效应,其标准化间接效应分别为0.043(95% CI: 0.018~0.081)、0.033(95% CI:0.015~0.058);自评健康状况通过心理健康问题产生间接效应,其标准化间接效应为0.073(95% CI:0.033~0.138);心理健康问题和中心性肥胖对慢性病共病产生直接效应,其标准化直接效应分别为0.229(95% CI:0.111~0.348)、0.198(95% CI:0.085~0.310)。
结论 应该加强年龄较大、睡眠质量差、有心理健康问题、中心性肥胖和自评健康状况差的男性戒毒人员慢性病的防控和管理,降低多种慢性病共病的患病风险。
, authors=李熙敏
1, 2, 阮春怡
1, 2, 史睿敏
1, 2, 保清柔
1, 2, 顾帆
1, 2, 陈莉
1, 2, 蔡乐
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李熙敏(1998—),女,硕士在读,研究方向:流行病与卫生统计学
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=FkhPHP+ZR/UfOeftif1hQg==, magXml=1vpWXkdOcZwiwHSr5MXIOQ==, pdfUrl=null, pdf=aRk/M1L00GyOHEv/Dkukdw==, pdfFileSize=744621, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=GOLpvYw217bpbFP8nNtY3A==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=pPLhnX0/N6h9EoLY3xPcsw==, mapNumber=null, fund=null)}, authors=[Author(id=1324078337206923329, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1324078337303392324, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, authorId=1324078337206923329, language=EN, stringName=Xi-min LI, firstName=Xi-min, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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Structural equation modelling of factors influencing the prevalence of multimorbidity of five chronic NCDs among male detoxification addicts under compulsory isolations, figureFileSmall=1PHihzp3zAr2a7QWFkd2Iw==, figureFileBig=GOLpvYw217bpbFP8nNtY3A==, tableContent=null), ArticleFig(id=1324078342537883763, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, language=CN, label=图1, caption=
男性强制戒毒人员五种慢性病共病影响因素的结构方程模型注:图中路径上数值均为标准化路径系数;*表示P<0.05;**表示P<0.001。
, figureFileSmall=1PHihzp3zAr2a7QWFkd2Iw==, figureFileBig=GOLpvYw217bpbFP8nNtY3A==, tableContent=null), ArticleFig(id=1324078342827290741, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, language=EN, label=Table 1, caption=
Prevalence and multimorbidity of five chronic NCDs among male detoxification addicts under compulsory isolations [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 特征 | 高血压 | 糖尿病 | 冠心病 | 脑卒中 | 慢性阻塞性肺病 | 慢性病共病 |
|---|
| 年龄(岁) | | | | | | |
| 18~24 | 6(13.3) | 0(0.0) | 0(0.0) | 0(0.0) | 0(0.0 | 0(0.0) |
| 25~34 | 103(33.7) | 0(0.0) | 0(0.0) | 0(0.0) | 2(0.7) | 1(0.3) |
| 35~44 | 130(39.9) | 12(3.7) | 4(1.2) | 2(0.6) | 2(0.6) | 11(3.4) |
| 45~54 | 141(58.8) | 13(5.4) | 10(4.2) | 4(1.7) | 8(3.3) | 27(11.3) |
| 55~64 | 66(73.3) | 12(13.3) | 8(8.9) | 6(6.7) | 8(8.9) | 21(23.3) |
| ≥65 | 13(92.9)** | 2(14.3)** | 2(14.3)** | 1(7.1)** | 4(28.6)** | 7(50.0)** |
| 民族 | | | | | | |
| 汉族 | 279(46.7) | 21(3.5) | 19(3.2)* | 9(1.5) | 11(1.8) | 41(6.9) |
| 少数民族 | 180(42.5) | 18(4.2) | 5(1.2) | 4(0.9) | 13(3.1) | 26(6.1) |
| 居住地 | | | | | | |
| 农村 | 356(43.3) | 29(3.5) | 13(1.6) | 10(1.2) | 19(2.3) | 47(5.7) |
| 城市 | 103(52.0)* | 10(5.1) | 11(5.6)* | 3(1.5) | 5(2.5) | 20(10.1)* |
| 受教育程度 | | | | | | |
| 文盲 | 73(51.4) | 6(4.2) | 4(2.8) | 5(3.5)* | 7(4.9)* | 12(8.5) |
| 小学及以上 | 386(43.9) | 33(3.8) | 20(2.3) | 8(0.9) | 17(1.9) | 55(6.3) |
| 睡眠质量 | | | | | | |
| 好 | 127(46.0) | 5(1.8) | 2(0.7) | 0(0.0) | 4(1.4) | 10(3.6) |
| 差 | 332(44.6) | 34(4.6)* | 22(3.0)* | 13(1.7)* | 20(2.7) | 57(7.7)* |
| 焦虑 | | | | | | |
| 否 | 406(43.7) | 30(3.2) | 16(1.7) | 9(1.0) | 21(2.3) | 48(5.2) |
| 是 | 53(58.2)* | 9(9.9)* | 8(8.8)** | 4(4.4)* | 3(3.3) | 19(20.9)** |
| 抑郁 | | | | | | |
| 否 | 420(44.2) | 32(3.4) | 22(2.3) | 11(1.2) | 22(2.3) | 57(6.0) |
| 是 | 39(55.7) | 7(10.0)* | 2(2.9) | 2(2.9) | 2(2.9) | 10(14.3)* |
| 肥胖 | | | | | | |
| 否 | 397(42.4) | 37(4.0) | 19(2.0) | 11(1.2) | 24(2.6) | 61(6.5) |
| 是 | 62(72.9)** | 2(2.4) | 5(5.9)* | 2(2.4) | 0(0.0) | 6(7.1) |
| 中心性肥胖 | | | | | | |
| 否 | 218(35.8) | 15(2.5) | 12(2.0) | 4(0.7) | 12(2.0) | 30(4.9) |
| 是 | 241(58.5)** | 24(5.8)* | 12(2.9) | 9(2.2)* | 12(2.9) | 37(9.0)* |
| 自评健康状况 | | | | | | |
| 好 | 29(35.4) | 0(0.0) | 0(0.0) | 0(0.0) | 1(1.2) | 0(0.0) |
| 一般 | 335(42.5) | 16(2.0) | 9(1.1) | 5(0.6) | 11(1.4) | 30(3.8) |
| 差 | 95(63.3)** | 23(15.3)** | 15(10.0)** | 8(5.3)** | 12(8.0)** | 37(24.7)** |
| 吸毒数量(种) | | | | | | |
| 1 | 346(46.1) | 33(4.4) | 18(2.4) | 8(1.1) | 22(2.9) | 53(7.1) |
| ≥2 | 113(41.7) | 6(2.2) | 6(2.2) | 5(1.8) | 2(0.7) | 14(5.2) |
| 吸毒年限(年) | | | | | | |
| ≤5 | 59(40.7) | 7(4.8) | 2(1.4) | 2(1.4) | 3(2.1) | 7(4.8) |
| 6~15 | 218(41.3) | 14(2.7) | 10(1.9) | 4(0.8) | 8(1.5) | 26(4.9) |
| 16~25 | 77(40.3) | 8(4.2) | 3(1.6) | 2(1.0) | 5(2.6) | 10(5.2) |
| ≥26 | 105(66.9)** | 10(6.4) | 9(5.7) | 5(3.2) | 8(5.1) | 24(15.3)** |
| 合计 | 459(45.0) | 39(3.8) | 24(2.4) | 13(1.3) | 24(2.4) | 67(6.6) |
), ArticleFig(id=1324078344496623734, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, language=CN, label=表1, caption=
男性强制戒毒人员五种慢性病患病及共病情况[n(%)]
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| 特征 | 高血压 | 糖尿病 | 冠心病 | 脑卒中 | 慢性阻塞性肺病 | 慢性病共病 |
|---|
| 年龄(岁) | | | | | | |
| 18~24 | 6(13.3) | 0(0.0) | 0(0.0) | 0(0.0) | 0(0.0 | 0(0.0) |
| 25~34 | 103(33.7) | 0(0.0) | 0(0.0) | 0(0.0) | 2(0.7) | 1(0.3) |
| 35~44 | 130(39.9) | 12(3.7) | 4(1.2) | 2(0.6) | 2(0.6) | 11(3.4) |
| 45~54 | 141(58.8) | 13(5.4) | 10(4.2) | 4(1.7) | 8(3.3) | 27(11.3) |
| 55~64 | 66(73.3) | 12(13.3) | 8(8.9) | 6(6.7) | 8(8.9) | 21(23.3) |
| ≥65 | 13(92.9)** | 2(14.3)** | 2(14.3)** | 1(7.1)** | 4(28.6)** | 7(50.0)** |
| 民族 | | | | | | |
| 汉族 | 279(46.7) | 21(3.5) | 19(3.2)* | 9(1.5) | 11(1.8) | 41(6.9) |
| 少数民族 | 180(42.5) | 18(4.2) | 5(1.2) | 4(0.9) | 13(3.1) | 26(6.1) |
| 居住地 | | | | | | |
| 农村 | 356(43.3) | 29(3.5) | 13(1.6) | 10(1.2) | 19(2.3) | 47(5.7) |
| 城市 | 103(52.0)* | 10(5.1) | 11(5.6)* | 3(1.5) | 5(2.5) | 20(10.1)* |
| 受教育程度 | | | | | | |
| 文盲 | 73(51.4) | 6(4.2) | 4(2.8) | 5(3.5)* | 7(4.9)* | 12(8.5) |
| 小学及以上 | 386(43.9) | 33(3.8) | 20(2.3) | 8(0.9) | 17(1.9) | 55(6.3) |
| 睡眠质量 | | | | | | |
| 好 | 127(46.0) | 5(1.8) | 2(0.7) | 0(0.0) | 4(1.4) | 10(3.6) |
| 差 | 332(44.6) | 34(4.6)* | 22(3.0)* | 13(1.7)* | 20(2.7) | 57(7.7)* |
| 焦虑 | | | | | | |
| 否 | 406(43.7) | 30(3.2) | 16(1.7) | 9(1.0) | 21(2.3) | 48(5.2) |
| 是 | 53(58.2)* | 9(9.9)* | 8(8.8)** | 4(4.4)* | 3(3.3) | 19(20.9)** |
| 抑郁 | | | | | | |
| 否 | 420(44.2) | 32(3.4) | 22(2.3) | 11(1.2) | 22(2.3) | 57(6.0) |
| 是 | 39(55.7) | 7(10.0)* | 2(2.9) | 2(2.9) | 2(2.9) | 10(14.3)* |
| 肥胖 | | | | | | |
| 否 | 397(42.4) | 37(4.0) | 19(2.0) | 11(1.2) | 24(2.6) | 61(6.5) |
| 是 | 62(72.9)** | 2(2.4) | 5(5.9)* | 2(2.4) | 0(0.0) | 6(7.1) |
| 中心性肥胖 | | | | | | |
| 否 | 218(35.8) | 15(2.5) | 12(2.0) | 4(0.7) | 12(2.0) | 30(4.9) |
| 是 | 241(58.5)** | 24(5.8)* | 12(2.9) | 9(2.2)* | 12(2.9) | 37(9.0)* |
| 自评健康状况 | | | | | | |
| 好 | 29(35.4) | 0(0.0) | 0(0.0) | 0(0.0) | 1(1.2) | 0(0.0) |
| 一般 | 335(42.5) | 16(2.0) | 9(1.1) | 5(0.6) | 11(1.4) | 30(3.8) |
| 差 | 95(63.3)** | 23(15.3)** | 15(10.0)** | 8(5.3)** | 12(8.0)** | 37(24.7)** |
| 吸毒数量(种) | | | | | | |
| 1 | 346(46.1) | 33(4.4) | 18(2.4) | 8(1.1) | 22(2.9) | 53(7.1) |
| ≥2 | 113(41.7) | 6(2.2) | 6(2.2) | 5(1.8) | 2(0.7) | 14(5.2) |
| 吸毒年限(年) | | | | | | |
| ≤5 | 59(40.7) | 7(4.8) | 2(1.4) | 2(1.4) | 3(2.1) | 7(4.8) |
| 6~15 | 218(41.3) | 14(2.7) | 10(1.9) | 4(0.8) | 8(1.5) | 26(4.9) |
| 16~25 | 77(40.3) | 8(4.2) | 3(1.6) | 2(1.0) | 5(2.6) | 10(5.2) |
| ≥26 | 105(66.9)** | 10(6.4) | 9(5.7) | 5(3.2) | 8(5.1) | 24(15.3)** |
| 合计 | 459(45.0) | 39(3.8) | 24(2.4) | 13(1.3) | 24(2.4) | 67(6.6) |
), ArticleFig(id=1324078344614064247, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, language=EN, label=Table 2, caption=
The effects and pathways of five influencing factors on the multimorbidity of chronic NCDs
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| 变量 | 路径 | 直接效应 β(95%CI) | 路径 | 间接效应β(95%CI) | 总效应β(95%CI) |
|---|
| 年龄 | 年龄→慢性病共病 | 0.362(0.254~0.456)** | 年龄→心理健康问题→慢性病共病 | 0.046(0.016~0.095)* | 0.474(0.290~0.680)** |
| | | 年龄→自评健康状况→慢性病共病 | 0.066(0.033~0.103)** | |
| 睡眠质量 | 睡眠质量→慢性病共病 | 0.181(0.054~0.328)* | 睡眠质量→心理健康问题→慢性病共病 | 0.043(0.018~0.081)* | 0.257(0.076~0.486)* |
| | | 睡眠质量→自评健康状况→慢性病共病 | 0.033(0.015~0.058)* | |
| 心理健康问题 | 心理健康问题→慢性病共病 | 0.229(0.111~0.348)** | | | 0.229(0.111~0.348)** |
| 中心性肥胖 | 中心性肥胖→慢性病共病 | 0.198(0.085~0.310)* | | | 0.198(0.085~0.310)* |
| 自评健康状况 | 自评健康状况→慢性病共病 | 0.220(0.110~0.325)** | 自评健康状况→心理健康问题→慢性病共病 | 0.073(0.033~0.138)** | 0.293(0.130~0.483)** |
), ArticleFig(id=1324078344744087672, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078335990575158, language=CN, label=表2, caption=
五种影响因素对慢性病共病影响的效应及作用路径
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 路径 | 直接效应 β(95%CI) | 路径 | 间接效应β(95%CI) | 总效应β(95%CI) |
|---|
| 年龄 | 年龄→慢性病共病 | 0.362(0.254~0.456)** | 年龄→心理健康问题→慢性病共病 | 0.046(0.016~0.095)* | 0.474(0.290~0.680)** |
| | | 年龄→自评健康状况→慢性病共病 | 0.066(0.033~0.103)** | |
| 睡眠质量 | 睡眠质量→慢性病共病 | 0.181(0.054~0.328)* | 睡眠质量→心理健康问题→慢性病共病 | 0.043(0.018~0.081)* | 0.257(0.076~0.486)* |
| | | 睡眠质量→自评健康状况→慢性病共病 | 0.033(0.015~0.058)* | |
| 心理健康问题 | 心理健康问题→慢性病共病 | 0.229(0.111~0.348)** | | | 0.229(0.111~0.348)** |
| 中心性肥胖 | 中心性肥胖→慢性病共病 | 0.198(0.085~0.310)* | | | 0.198(0.085~0.310)* |
| 自评健康状况 | 自评健康状况→慢性病共病 | 0.220(0.110~0.325)** | 自评健康状况→心理健康问题→慢性病共病 | 0.073(0.033~0.138)** | 0.293(0.130~0.483)** |
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