Article(id=1324078306135520137, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078175000605624, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202506249, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1750003200000, receivedDateStr=2025-06-16, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793614468368, onlineDateStr=2026-11-02, pubDate=1769270400000, pubDateStr=2026-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793614468368, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793614468368, creator=13701087609, updateTime=1793614468368, updator=13701087609, issue=Issue{id=1324078175000605624, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='2', pageStart='193', pageEnd='384', issueExtLink='null', onlineDate='null', pubDate='1769270400000', pubDateStr='2026-01-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793614437103, creator='13701087609', updateTime=1793614526046, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324078548130082942, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078175000605624, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324078548130082943, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078175000605624, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=349, endPage=355, ext={EN=ArticleExt(id=1324078306382984074, articleId=1324078306135520137, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Analysis of the effectiveness of lipid, blood glucose and blood pressure interventions in high-risk populations for cardiovascular disease in the Inner Mongolia Autonomous Region, columnId=1228016573156360233, journalTitle=Modern Preventive Medicine, columnName=Disease Control and Prevention, runingTitle=null, highlight=null, articleAbstract=
Objective

To evaluate the effect of a comprehensive intervention program for individuals at high risk of cardiovascular disease in the Inner Mongolia Autonomous Region, and to provide a reference for the prevention and control of cardiovascular diseases in this region.

Methods

Data from the Inner Mongolia Autonomous Region Cardiovascular Disease High-Risk Population Early Screening and Comprehensive Intervention Project (2015—2024) were used to identify 3 354 high-risk individuals. Based on inclusion and exclusion criteria, these participants received comprehensive interventions over a 10-year period. Changes in lipid profiles, blood glucose, and blood pressure levels before and after the intervention were analyzed to assess the effectiveness of the program.

Results

After 10 years of comprehensive intervention, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels decreased (t=23.477, t=18.013), while high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels increased (t=-4.096, t=-9.154). Fasting blood glucose levels also increased (t=-14.725). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) decreased from 160.16±22.76 mmHg and 93.10±12.75 mmHg to 140.98±18.65 mmHg and 84.89±10.94 mmHg, respectively (t=49.481, t=38.451). All these changes were statistically significant (P<0.001). Analysis of intervention effects showed that the rates of dyslipidemia and abnormal blood pressure decreased (χ2=23.369, P<0.001; χ2=359.194, P<0.001), while the rate of abnormal blood glucose increased (χ2=357.752, P<0.001), with all differences being statistically significant.

Conclusion

The implementation of comprehensive interventions for populations at high risk of cardiovascular disease in the Inner Mongolia Autonomous Region is beneficial in reducing the prevalence of dyslipidemia and hypertension, highlighting its public health significance. However, close monitoring of triglyceride (TG) and fasting blood glucose levels is necessary, and further research is needed to explore their impact on cardiovascular disease.

, authors=Bu-qi NA1, Li-ying QIAO1, Wei XU2, Jia-lin FAN1, Yun-feng XI1, authorsList=Bu-qi NA, Li-ying QIAO, Wei XU, Jia-lin FAN, Yun-feng XI, authorCompany=null, correspAuthors=Yun-feng XI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324078306919854989, articleId=1324078306135520137, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=内蒙古自治区心血管病高危人群血脂、血糖、血压干预效果分析, columnId=1228016573844226129, journalTitle=现代预防医学, columnName=疾病预防控制, runingTitle=null, highlight=null, articleAbstract=
目的

分析针对内蒙古自治区心血管病高危人群实施综合干预的效果,并为内蒙古自治区心血管病的防控提供科学依据。

方法

利用2015—2024年内蒙古自治区心血管病高危人群早期筛查与综合干预项目数据,根据纳入排除标准,确定3 354名心血管病高危对象,对其进行10年的综合干预。通过分析综合干预前后血脂、血糖和血压水平的变化,以评价综合干预措施的有效性。

结果

通过10年综合干预,心血管病高危人群的TC和LDL-C水平下降(t=23.477,t=18.013),HDL-C和TG水平上升(t=-4.096,t=-9.154);空腹血糖水平上升(t=-14.725);SBP从160.16±22.76 mmHg下降至140.98±18.65 mmHg(t=49.481),DBP从93.10±12.75 mmHg下降至84.89±10.94 mmHg(t=38.451),差异均有统计学意义(P<0.001)。进行干预效果分析显示,血脂和血压异常率均呈下降趋势(χ2=23.369,P<0.001;χ2=359.194,P<0.001),而血糖异常率呈上升趋势(χ2=357.75,P<0.001),差异均有统计学意义。

结论

对内蒙古自治区心血管病高危人群实施综合干预有利于降低血脂异常率和血压异常率,具有重要公共卫生意义,但需要做好TG和空腹血糖水平的监测工作,进一步探讨其对心血管病的影响。

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(In Chinese), articleTitle=Comprehensive intervention effects on high-risk populations for cardiovascular disease based on panel data analysis, refAbstract=null)], funds=[Fund(id=1324078314100503486, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, awardId=Z195110010004, language=CN, fundingSource=中央转移支付地方重大公共卫生项目中国心血管病高危人群早期筛查与干预项目(Z195110010004), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1324078308748571534, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, xref=1., ext=[AuthorCompanyExt(id=1324078308761154447, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, companyId=1324078308748571534, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Inner Mongolia Autonomous Region Center for Disease Control and Prevention (Inner Mongolia Autonomous Region Academy of Preventive Medicine), Hohhot, Inner Mongolia 010080, China), AuthorCompanyExt(id=1324078308773737360, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, companyId=1324078308748571534, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.内蒙古自治区疾病预防控制中心(内蒙古自治区预防医学科学院),内蒙古 呼和浩特 010080)]), AuthorCompany(id=1324078308857623441, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, xref=2., ext=[AuthorCompanyExt(id=1324078308861817746, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, companyId=1324078308857623441, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=2.国家心血管病中心,中国医学科学院北京协和医学院阜外医院)])], figs=[ArticleFig(id=1324078311533589430, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=EN, label=Table 1, caption=

Changes in lipid levels in high-risk populations for cardiovascular disease before and after intervention,2015—2024

, figureFileSmall=null, figureFileBig=null, tableContent=
特征TC(mmol/L)HDL-C(mmol/L)
干预前干预后t值P值干预前干预后t值P值
合计4.76±1.094.21±1.2923.477<0.0011.38±0.401.41±0.40-4.096<0.001
年龄分组(岁)
35~394.33±0.864.02±1.242.0150.0481.18±0.371.31±0.40-2.7160.008
40~494.55±1.024.29±1.284.636<0.0011.33±0.401.38±0.40-2.9890.003
50~594.84±1.104.27±1.3215.934<0.0011.37±0.391.40±0.39-2.2110.027
60~694.80±1.104.14±1.2716.498<0.0011.41±0.411.43±0.41-1.4450.149
70~754.77±1.124.09±1.276.693<0.0011.41±0.391.44±0.43-0.8730.384
性别
男4.44±1.013.89±1.1616.821<0.0011.25±0.401.33±0.39-7.650<0.001
女4.98±1.094.44±1.3416.820<0.0011.47±0.381.46±0.400.8150.415
民族
汉族4.76±1.094.21±1.2923.100<0.0011.38±0.401.41±0.40-3.881<0.001
蒙古族4.81±1.144.38±1.393.5520.0011.36±0.391.40±0.53-0.8740.384
其他4.71±0.884.38±1.392.5630.0151.31±0.441.41±0.32-1.3770.178
城乡
城市4.86±1.144.19±1.1916.149<0.0011.27±0.391.28±0.33-1.2770.202
农村4.73±1.074.22±1.3318.129<0.0011.41±0.401.45±0.42-3.900<0.001
文化程度
初中及以下4.78±1.074.24±1.3119.454<0.0011.42±0.401.43±0.40-1.7330.083
高中/中专4.73±1.154.09±1.2611.970<0.0011.29±0.371.35±0.37-3.619<0.001
大专及以上4.64±1.114.17±1.205.821<0.0011.22±0.421.32±0.44-3.741<0.001
不清楚/拒绝回答4.95±1.264.37±1.651.6940.1031.41±0.441.37±0.340.1760.861
饮酒
是4.73±1.104.15±1.209.239<0.0011.42±0.441.43±0.43-0.1790.858
否4.76±1.094.22±1.3121.650<0.0011.37±0.401.40±0.40-4.358<0.001
吸烟
是4.57±1.093.99±1.2511.968<0.0011.27±0.431.35±0.41-4.979<0.001
否4.81±1.094.27±1.3020.243<0.0011.41±0.391.42±0.40-1.9970.046
BMI(kg/m2)
<18.54.18±1.024.20±1.20-0.0850.9341.81±0.291.81±0.330.0580.954
18.5~23.94.71±1.104.29±1.338.223<0.0011.54±0.421.49±0.422.8870.004
24.0~27.94.81±1.134.21±1.2917.113<0.0011.37±0.381.39±0.40-2.5020.012
≥28.04.73±1.024.16±1.2714.442<0.0011.27±0.371.36±0.38-7.185<0.001
特征TG(mmol/L)LDL-C(mmol/L)
干预前干预后t值P值干预前干预后t值P值
合计1.63±0.801.78±0.91-9.154<0.0012.64±0.972.06±1.8418.013<0.001
年龄分组(岁)
35~391.88±0.981.95±1.24-0.5080.6132.31±0.761.84±1.053.3430.001
40~491.65±0.841.86±1.03-4.741<0.0012.48±0.952.06±1.088.386<0.001
50~591.66±0.801.82±0.91-6.186<0.0012.71±0.982.15±2.568.113<0.001
60~691.57±0.741.71±0.83-5.470<0.0012.67±0.961.97±1.0620.152<0.001
70~751.62±0.801.58±0.800.6550.5132.64±0.961.95±1.047.488<0.001
性别
男1.59±0.821.66±0.85-3.287<0.0012.47±0.931.86±1.8112.281<0.001
女1.66±0.781.86±0.94-8.981<0.0012.77±0.972.20±1.8513.222<0.01
民族
汉族1.63±0.801.78±0.91-9.136<0.052.64±0.972.06±1.8717.322<0.001
蒙古族1.67±0.791.79±0.89-1.1930.2352.74±0.992.21±1.114.998<0.001
其他1.50±0.651.53±0.80-0.1860.8542.65±0.901.95±0.913.3990.002
城乡
城市1.71±0.832.01±1.05-8.361<0.0012.82±1.021.99±1.0620.905<0.001
农村1.60±0.781.70±0.84-5.417<0.0012.59±0.942.08±2.0312.187<0.001
文化程度
初中及以下1.62±0.801.77±0.91-7.862<0.0012.62±0.942.07±2.0513.042<0.001
高中/中专1.61±0.771.82±0.94-5.133<0.0012.74±1.012.00±1.0715.733<0.001
大专及以上1.74±0.831.78±0.90-0.6760.5002.64±1.062.04±1.008.266<0.001
不清楚/拒绝回答1.63±1.031.67±1.02-0.2120.8342.84±1.052.45±1.181.3990.174
饮酒
是1.65±0.931.72±0.92-1.5290.1272.58±1.011.93±1.0811.273<0.001
否1.63±0.781.79±0.91-9.185<0.0012.65±0.962.08±1.9215.946<0.001
吸烟
是1.64±0.821.72±0.88-2.2400.0252.55±0.991.89±1.0515.470<0.001
否1.63±0.791.80±0.92-9.105<0.0012.67±0.962.11±2.0014.151<0.001
BMI(kg/m2)
<18.50.99±0.231.31±0.32-3.8890.0021.92±0.961.85±1.190.3490.732
18.5~23.91.35±0.671.60±0.90-7.499<0.0012.56±1.012.09±1.1110.523<0.001
24.0~27.91.64±0.791.80±0.90-6.820<0.0012.70±0.992.07±2.0012.055<0.001
≥28.01.82±0.821.88±0.92-1.9910.0472.63±0.882.03±2.009.794<0.001
), ArticleFig(id=1324078313064510391, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=CN, label=表1, caption=

2015—2024年内蒙古自治区心血管病高危人群干预前后血脂水平变化情况

, figureFileSmall=null, figureFileBig=null, tableContent=
特征TC(mmol/L)HDL-C(mmol/L)
干预前干预后t值P值干预前干预后t值P值
合计4.76±1.094.21±1.2923.477<0.0011.38±0.401.41±0.40-4.096<0.001
年龄分组(岁)
35~394.33±0.864.02±1.242.0150.0481.18±0.371.31±0.40-2.7160.008
40~494.55±1.024.29±1.284.636<0.0011.33±0.401.38±0.40-2.9890.003
50~594.84±1.104.27±1.3215.934<0.0011.37±0.391.40±0.39-2.2110.027
60~694.80±1.104.14±1.2716.498<0.0011.41±0.411.43±0.41-1.4450.149
70~754.77±1.124.09±1.276.693<0.0011.41±0.391.44±0.43-0.8730.384
性别
男4.44±1.013.89±1.1616.821<0.0011.25±0.401.33±0.39-7.650<0.001
女4.98±1.094.44±1.3416.820<0.0011.47±0.381.46±0.400.8150.415
民族
汉族4.76±1.094.21±1.2923.100<0.0011.38±0.401.41±0.40-3.881<0.001
蒙古族4.81±1.144.38±1.393.5520.0011.36±0.391.40±0.53-0.8740.384
其他4.71±0.884.38±1.392.5630.0151.31±0.441.41±0.32-1.3770.178
城乡
城市4.86±1.144.19±1.1916.149<0.0011.27±0.391.28±0.33-1.2770.202
农村4.73±1.074.22±1.3318.129<0.0011.41±0.401.45±0.42-3.900<0.001
文化程度
初中及以下4.78±1.074.24±1.3119.454<0.0011.42±0.401.43±0.40-1.7330.083
高中/中专4.73±1.154.09±1.2611.970<0.0011.29±0.371.35±0.37-3.619<0.001
大专及以上4.64±1.114.17±1.205.821<0.0011.22±0.421.32±0.44-3.741<0.001
不清楚/拒绝回答4.95±1.264.37±1.651.6940.1031.41±0.441.37±0.340.1760.861
饮酒
是4.73±1.104.15±1.209.239<0.0011.42±0.441.43±0.43-0.1790.858
否4.76±1.094.22±1.3121.650<0.0011.37±0.401.40±0.40-4.358<0.001
吸烟
是4.57±1.093.99±1.2511.968<0.0011.27±0.431.35±0.41-4.979<0.001
否4.81±1.094.27±1.3020.243<0.0011.41±0.391.42±0.40-1.9970.046
BMI(kg/m2)
<18.54.18±1.024.20±1.20-0.0850.9341.81±0.291.81±0.330.0580.954
18.5~23.94.71±1.104.29±1.338.223<0.0011.54±0.421.49±0.422.8870.004
24.0~27.94.81±1.134.21±1.2917.113<0.0011.37±0.381.39±0.40-2.5020.012
≥28.04.73±1.024.16±1.2714.442<0.0011.27±0.371.36±0.38-7.185<0.001
特征TG(mmol/L)LDL-C(mmol/L)
干预前干预后t值P值干预前干预后t值P值
合计1.63±0.801.78±0.91-9.154<0.0012.64±0.972.06±1.8418.013<0.001
年龄分组(岁)
35~391.88±0.981.95±1.24-0.5080.6132.31±0.761.84±1.053.3430.001
40~491.65±0.841.86±1.03-4.741<0.0012.48±0.952.06±1.088.386<0.001
50~591.66±0.801.82±0.91-6.186<0.0012.71±0.982.15±2.568.113<0.001
60~691.57±0.741.71±0.83-5.470<0.0012.67±0.961.97±1.0620.152<0.001
70~751.62±0.801.58±0.800.6550.5132.64±0.961.95±1.047.488<0.001
性别
男1.59±0.821.66±0.85-3.287<0.0012.47±0.931.86±1.8112.281<0.001
女1.66±0.781.86±0.94-8.981<0.0012.77±0.972.20±1.8513.222<0.01
民族
汉族1.63±0.801.78±0.91-9.136<0.052.64±0.972.06±1.8717.322<0.001
蒙古族1.67±0.791.79±0.89-1.1930.2352.74±0.992.21±1.114.998<0.001
其他1.50±0.651.53±0.80-0.1860.8542.65±0.901.95±0.913.3990.002
城乡
城市1.71±0.832.01±1.05-8.361<0.0012.82±1.021.99±1.0620.905<0.001
农村1.60±0.781.70±0.84-5.417<0.0012.59±0.942.08±2.0312.187<0.001
文化程度
初中及以下1.62±0.801.77±0.91-7.862<0.0012.62±0.942.07±2.0513.042<0.001
高中/中专1.61±0.771.82±0.94-5.133<0.0012.74±1.012.00±1.0715.733<0.001
大专及以上1.74±0.831.78±0.90-0.6760.5002.64±1.062.04±1.008.266<0.001
不清楚/拒绝回答1.63±1.031.67±1.02-0.2120.8342.84±1.052.45±1.181.3990.174
饮酒
是1.65±0.931.72±0.92-1.5290.1272.58±1.011.93±1.0811.273<0.001
否1.63±0.781.79±0.91-9.185<0.0012.65±0.962.08±1.9215.946<0.001
吸烟
是1.64±0.821.72±0.88-2.2400.0252.55±0.991.89±1.0515.470<0.001
否1.63±0.791.80±0.92-9.105<0.0012.67±0.962.11±2.0014.151<0.001
BMI(kg/m2)
<18.50.99±0.231.31±0.32-3.8890.0021.92±0.961.85±1.190.3490.732
18.5~23.91.35±0.671.60±0.90-7.499<0.0012.56±1.012.09±1.1110.523<0.001
24.0~27.91.64±0.791.80±0.90-6.820<0.0012.70±0.992.07±2.0012.055<0.001
≥28.01.82±0.821.88±0.92-1.9910.0472.63±0.882.03±2.009.794<0.001
), ArticleFig(id=1324078313207116728, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=EN, label=Table 2, caption=

Changes in fasting blood glucose levels in high-risk populations for cardiovascular disease, before and after intervention, 2015-2024

, figureFileSmall=null, figureFileBig=null, tableContent=
特征空腹血糖(mmol/L)
干预前干预后t值P值
合计6.48±1.567.02±2.19-14.725<0.001
年龄分组(岁)
35~396.10±0.986.47±1.65-1.7920.078
40~496.33±1.556.96±2.23-7.551<0.001
50~596.56±1.707.04±2.24-8.126<0.001
60~696.50±1.447.02±2.11-8.946<0.001
70~756.45±1.237.20±2.24-4.330<0.001
性别
男6.51±1.567.07±2.24-9.267<0.001
女6.46±1.566.98±2.14-11.492<0.001
民族
汉族6.49±1.577.03±2.20-14.049<0.001
蒙古族6.22±1.176.89±2.01-4.839<0.001
其他6.38±1.426.87±1.79-1.9730.057
城乡
城市6.42±1.726.50±2.07-1.0990.272
农村6.50±1.507.19±2.20-16.621<0.001
文化程度
初中及以下6.52±1.557.16±2.22-14.889<0.001
高中/中专6.46±1.656.66±2.16-2.2560.024
大专及以上6.24±1.446.60±1.81-3.3360.001
不清楚/拒绝回答6.09±0.946.34±2.05-0.7810.442
饮酒
是6.62±1.697.31±2.21-6.051<0.001
否6.46±1.546.98±2.18-13.435<0.001
吸烟
是6.47±1.586.95±2.22-5.866<0.001
否6.49±1.557.04±2.18-13.614<0.001
BMI(kg/m2)
<18.56.16±0.576.46±1.46-0.7040.494
18.5~23.96.27±1.456.62±1.79-5.181<0.001
24.0~27.96.49±1.637.07±2.19-10.773<0.001
≥28.06.61±1.517.24±2.40-8.730<0.05
), ArticleFig(id=1324078313291002809, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=CN, label=表2, caption=

2015—2024年内蒙古自治区心血管病高危人群干预前后空腹血糖水平变化情况

, figureFileSmall=null, figureFileBig=null, tableContent=
特征空腹血糖(mmol/L)
干预前干预后t值P值
合计6.48±1.567.02±2.19-14.725<0.001
年龄分组(岁)
35~396.10±0.986.47±1.65-1.7920.078
40~496.33±1.556.96±2.23-7.551<0.001
50~596.56±1.707.04±2.24-8.126<0.001
60~696.50±1.447.02±2.11-8.946<0.001
70~756.45±1.237.20±2.24-4.330<0.001
性别
男6.51±1.567.07±2.24-9.267<0.001
女6.46±1.566.98±2.14-11.492<0.001
民族
汉族6.49±1.577.03±2.20-14.049<0.001
蒙古族6.22±1.176.89±2.01-4.839<0.001
其他6.38±1.426.87±1.79-1.9730.057
城乡
城市6.42±1.726.50±2.07-1.0990.272
农村6.50±1.507.19±2.20-16.621<0.001
文化程度
初中及以下6.52±1.557.16±2.22-14.889<0.001
高中/中专6.46±1.656.66±2.16-2.2560.024
大专及以上6.24±1.446.60±1.81-3.3360.001
不清楚/拒绝回答6.09±0.946.34±2.05-0.7810.442
饮酒
是6.62±1.697.31±2.21-6.051<0.001
否6.46±1.546.98±2.18-13.435<0.001
吸烟
是6.47±1.586.95±2.22-5.866<0.001
否6.49±1.557.04±2.18-13.614<0.001
BMI(kg/m2)
<18.56.16±0.576.46±1.46-0.7040.494
18.5~23.96.27±1.456.62±1.79-5.181<0.001
24.0~27.96.49±1.637.07±2.19-10.773<0.001
≥28.06.61±1.517.24±2.40-8.730<0.05
), ArticleFig(id=1324078313454580666, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=EN, label=Table 3, caption=

Changes in blood pressure before and after an intervention in populations at high risk of cardiovascular disease, 2015-2024

, figureFileSmall=null, figureFileBig=null, tableContent=
特征SBP(mmHg)DBP(mmHg)
干预前干预后t值P值干预前干预后t值P值
合计160.16±22.76140.98±18.6549.481<0.00193.10±12.7584.89±10.9438.451<0.001
年龄分组(岁)
35~39144.06±21.53133.25±19.634.822<0.00191.56±14.3988.09±12.311.8870.063
40~49156.92±22.62137.00±17.6921.416<0.00196.64±13.4188.19±10.9015.547<0.001
50~59160.08±22.93140.40±18.0332.639<0.00194.02±12.5185.63±10.5925.563<0.001
60~69162.45±22.67143.43±19.3428.803<0.00191.19±12.1082.74±10.7823.936<0.001
70~75162.82±21.70146.00±19.349.255<0.00187.15±11.9480.95±10.316.733<0.001
性别
男156.99±22.48140.53±18.0428.310<0.00194.27±12.7686.53±11.3123.020<0.001
女162.39±22.69141.31±19.0741.033<0.00192.28±12.6983.74±10.5330.935<0.001
民族
汉族160.29±22.80141.17±18.7448.170<0.00193.07±12.7584.86±10.9537.585<0.001
蒙古族157.12±21.91136.62±16.6810.339<0.00192.89±12.3885.25±11.147.043<0.001
其他159.29±21.69141.43±15.084.522<0.00197.34±14.2186.84±9.624.094<0.001
城乡
城市156.04±22.64137.45±16.2024.729<0.00190.67±12.2481.27±9.9823.686<0.001
农村161.57±22.63142.20±19.2842.857<0.00193.95±12.8386.14±10.9830.957<0.001
文化程度
初中及以下162.19±22.47142.56±18.8642.948<0.00193.44±12.6285.38±11.1232.629<0.001
高中/中专155.21±22.83137.81±17.9218.872<0.00191.56±12.7883.18±10.3616.399<0.001
大专及以上153.22±22.40134.42±15.9615.273<0.00193.48±13.6484.30±10.0311.413<0.001
不清楚/拒绝回答155.98±20.50134.77±16.755.526<0.00193.25±13.7085.02±12.813.9290.001
饮酒
是161.74±20.83143.82±17.7317.721<0.00197.19±12.1188.23±11.0214.683<0.001
否159.94±23.00140.60±18.7446.254<0.00192.54±12.7484.43±10.8535.570<0.001
吸烟
是155.93±22.99139.20±18.6820.725<0.00193.57±13.2585.85±11.6216.175<0.001
否161.36±22.55141.50±18.6145.088<0.00192.97±12.6184.62±10.7335.048<0.001
BMI(kg/m2)
<18.5148.29±33.27140.18±19.041.2520.23386.82±18.5481.54±8.511.1710.263
18.5~23.9155.81±24.21139.80±19.8519.301<0.00188.83±13.1482.71±10.3613.587<0.001
24.0~27.9159.77±22.56141.12±18.3832.830<0.00192.97±12.4785.10±10.7425.227<0.001
≥28.0163.90±21.15141.65±18.1332.734<0.00196.37±11.8486.18±11.4227.026<0.001
), ArticleFig(id=1324078313681073083, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=CN, label=表3, caption=

2015—2024年内蒙古自治区心血管病高危人群干预前后血压水平变化情况

, figureFileSmall=null, figureFileBig=null, tableContent=
特征SBP(mmHg)DBP(mmHg)
干预前干预后t值P值干预前干预后t值P值
合计160.16±22.76140.98±18.6549.481<0.00193.10±12.7584.89±10.9438.451<0.001
年龄分组(岁)
35~39144.06±21.53133.25±19.634.822<0.00191.56±14.3988.09±12.311.8870.063
40~49156.92±22.62137.00±17.6921.416<0.00196.64±13.4188.19±10.9015.547<0.001
50~59160.08±22.93140.40±18.0332.639<0.00194.02±12.5185.63±10.5925.563<0.001
60~69162.45±22.67143.43±19.3428.803<0.00191.19±12.1082.74±10.7823.936<0.001
70~75162.82±21.70146.00±19.349.255<0.00187.15±11.9480.95±10.316.733<0.001
性别
男156.99±22.48140.53±18.0428.310<0.00194.27±12.7686.53±11.3123.020<0.001
女162.39±22.69141.31±19.0741.033<0.00192.28±12.6983.74±10.5330.935<0.001
民族
汉族160.29±22.80141.17±18.7448.170<0.00193.07±12.7584.86±10.9537.585<0.001
蒙古族157.12±21.91136.62±16.6810.339<0.00192.89±12.3885.25±11.147.043<0.001
其他159.29±21.69141.43±15.084.522<0.00197.34±14.2186.84±9.624.094<0.001
城乡
城市156.04±22.64137.45±16.2024.729<0.00190.67±12.2481.27±9.9823.686<0.001
农村161.57±22.63142.20±19.2842.857<0.00193.95±12.8386.14±10.9830.957<0.001
文化程度
初中及以下162.19±22.47142.56±18.8642.948<0.00193.44±12.6285.38±11.1232.629<0.001
高中/中专155.21±22.83137.81±17.9218.872<0.00191.56±12.7883.18±10.3616.399<0.001
大专及以上153.22±22.40134.42±15.9615.273<0.00193.48±13.6484.30±10.0311.413<0.001
不清楚/拒绝回答155.98±20.50134.77±16.755.526<0.00193.25±13.7085.02±12.813.9290.001
饮酒
是161.74±20.83143.82±17.7317.721<0.00197.19±12.1188.23±11.0214.683<0.001
否159.94±23.00140.60±18.7446.254<0.00192.54±12.7484.43±10.8535.570<0.001
吸烟
是155.93±22.99139.20±18.6820.725<0.00193.57±13.2585.85±11.6216.175<0.001
否161.36±22.55141.50±18.6145.088<0.00192.97±12.6184.62±10.7335.048<0.001
BMI(kg/m2)
<18.5148.29±33.27140.18±19.041.2520.23386.82±18.5481.54±8.511.1710.263
18.5~23.9155.81±24.21139.80±19.8519.301<0.00188.83±13.1482.71±10.3613.587<0.001
24.0~27.9159.77±22.56141.12±18.3832.830<0.00192.97±12.4785.10±10.7425.227<0.001
≥28.0163.90±21.15141.65±18.1332.734<0.00196.37±11.8486.18±11.4227.026<0.001
), ArticleFig(id=1324078313760764860, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=EN, label=Table 4, caption=

Outcomes of interventions for high-risk populations with cardiovascular disease and ‘three highs’ from 2015 to 2024

, figureFileSmall=null, figureFileBig=null, tableContent=
项目2015年
例数(构成比%)
2016年
例数(构成比%)
2020年
例数(构成比%)
2024年
例数(构成比%)
趋势χ2值P值
血脂23.369<0.001
正常1 367(40.8)1 384(41.3)1 609(48.0)1 499(44.7)
异常1 987(59.2)1 970(58.7)1 745(52.0)1 855(55.3)
血糖357.752<0.001
正常2 605(77.7)2 743(81.8)2 699(80.5)1 905(56.8)
异常749(22.3)611(18.2)655(19.5)1 449(43.2)
血压359.194<0.001
正常613(18.3)1 313(39.1)1 119(33.4)1 450(43.2)
异常2 741(81.7)2 041(60.9)2 235(66.6)1 904(56.8)
), ArticleFig(id=1324078313832068029, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078306135520137, language=CN, label=表4, caption=

内蒙古自治区2015—2024年心血管病高危人群“三高”干预效果情况

, figureFileSmall=null, figureFileBig=null, tableContent=
项目2015年
例数(构成比%)
2016年
例数(构成比%)
2020年
例数(构成比%)
2024年
例数(构成比%)
趋势χ2值P值
血脂23.369<0.001
正常1 367(40.8)1 384(41.3)1 609(48.0)1 499(44.7)
异常1 987(59.2)1 970(58.7)1 745(52.0)1 855(55.3)
血糖357.752<0.001
正常2 605(77.7)2 743(81.8)2 699(80.5)1 905(56.8)
异常749(22.3)611(18.2)655(19.5)1 449(43.2)
血压359.194<0.001
正常613(18.3)1 313(39.1)1 119(33.4)1 450(43.2)
异常2 741(81.7)2 041(60.9)2 235(66.6)1 904(56.8)
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内蒙古自治区心血管病高危人群血脂、血糖、血压干预效果分析
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现代预防医学 | 疾病预防控制 2026,53(2): 349-355
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现代预防医学 |疾病预防控制 2026 , 53 (2) : 349 -355
内蒙古自治区心血管病高危人群血脂、血糖、血压干预效果分析
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那布其1, 乔丽颖1, 许巍2, 范嘉麟1, 席云峰1
作者信息
  • 1.内蒙古自治区疾病预防控制中心(内蒙古自治区预防医学科学院),内蒙古 呼和浩特 010080
  • 2.国家心血管病中心,中国医学科学院北京协和医学院阜外医院
通讯作者:
席云峰,E-mail:
作者简介:

那布其(1993—),女,硕士,主管医师,研究方向:心血管病防控

Analysis of the effectiveness of lipid, blood glucose and blood pressure interventions in high-risk populations for cardiovascular disease in the Inner Mongolia Autonomous Region
Bu-qi NA1, Li-ying QIAO1, Wei XU2, Jia-lin FAN1, Yun-feng XI1
Affiliations
  • Inner Mongolia Autonomous Region Center for Disease Control and Prevention (Inner Mongolia Autonomous Region Academy of Preventive Medicine), Hohhot, Inner Mongolia 010080, China
出版时间: 2026-01-25 doi: 10.20043/j.cnki.MPM.202506249
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目的

分析针对内蒙古自治区心血管病高危人群实施综合干预的效果,并为内蒙古自治区心血管病的防控提供科学依据。

方法

利用2015—2024年内蒙古自治区心血管病高危人群早期筛查与综合干预项目数据,根据纳入排除标准,确定3 354名心血管病高危对象,对其进行10年的综合干预。通过分析综合干预前后血脂、血糖和血压水平的变化,以评价综合干预措施的有效性。

结果

通过10年综合干预,心血管病高危人群的TC和LDL-C水平下降(t=23.477,t=18.013),HDL-C和TG水平上升(t=-4.096,t=-9.154);空腹血糖水平上升(t=-14.725);SBP从160.16±22.76 mmHg下降至140.98±18.65 mmHg(t=49.481),DBP从93.10±12.75 mmHg下降至84.89±10.94 mmHg(t=38.451),差异均有统计学意义(P<0.001)。进行干预效果分析显示,血脂和血压异常率均呈下降趋势(χ2=23.369,P<0.001;χ2=359.194,P<0.001),而血糖异常率呈上升趋势(χ2=357.75,P<0.001),差异均有统计学意义。

结论

对内蒙古自治区心血管病高危人群实施综合干预有利于降低血脂异常率和血压异常率,具有重要公共卫生意义,但需要做好TG和空腹血糖水平的监测工作,进一步探讨其对心血管病的影响。

心血管病  /  高危人群  /  血脂  /  血糖  /  血压
Objective

To evaluate the effect of a comprehensive intervention program for individuals at high risk of cardiovascular disease in the Inner Mongolia Autonomous Region, and to provide a reference for the prevention and control of cardiovascular diseases in this region.

Methods

Data from the Inner Mongolia Autonomous Region Cardiovascular Disease High-Risk Population Early Screening and Comprehensive Intervention Project (2015—2024) were used to identify 3 354 high-risk individuals. Based on inclusion and exclusion criteria, these participants received comprehensive interventions over a 10-year period. Changes in lipid profiles, blood glucose, and blood pressure levels before and after the intervention were analyzed to assess the effectiveness of the program.

Results

After 10 years of comprehensive intervention, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels decreased (t=23.477, t=18.013), while high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels increased (t=-4.096, t=-9.154). Fasting blood glucose levels also increased (t=-14.725). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) decreased from 160.16±22.76 mmHg and 93.10±12.75 mmHg to 140.98±18.65 mmHg and 84.89±10.94 mmHg, respectively (t=49.481, t=38.451). All these changes were statistically significant (P<0.001). Analysis of intervention effects showed that the rates of dyslipidemia and abnormal blood pressure decreased (χ2=23.369, P<0.001; χ2=359.194, P<0.001), while the rate of abnormal blood glucose increased (χ2=357.752, P<0.001), with all differences being statistically significant.

Conclusion

The implementation of comprehensive interventions for populations at high risk of cardiovascular disease in the Inner Mongolia Autonomous Region is beneficial in reducing the prevalence of dyslipidemia and hypertension, highlighting its public health significance. However, close monitoring of triglyceride (TG) and fasting blood glucose levels is necessary, and further research is needed to explore their impact on cardiovascular disease.

Cardiovascular disease  /  High-risk population  /  Blood lipids  /  Blood glucose  /  Blood pressure
那布其, 乔丽颖, 许巍, 范嘉麟, 席云峰. 内蒙古自治区心血管病高危人群血脂、血糖、血压干预效果分析. 现代预防医学, 2026 , 53 (2) : 349 -355 . DOI: 10.20043/j.cnki.MPM.202506249
Bu-qi NA, Li-ying QIAO, Wei XU, Jia-lin FAN, Yun-feng XI. Analysis of the effectiveness of lipid, blood glucose and blood pressure interventions in high-risk populations for cardiovascular disease in the Inner Mongolia Autonomous Region[J]. Modern Preventive Medicine, 2026 , 53 (2) : 349 -355 . DOI: 10.20043/j.cnki.MPM.202506249
目前,心血管疾病(Cardiovascular disease, CVD)是我国面临的主要公共卫生问题,对人口健康构成严重威胁,患者人数估计为3.3亿[1]。内蒙古由心血管病造成的疾病负担高于其他地区[2],且整体呈增长趋势[3]。高血压、糖尿病、血脂异常是心血管病发生和死亡的重要危险因素,血脂、血糖、血压水平是其风险评估的主要指标[4]。自2015年,内蒙古自治区实施国家重大公共卫生专项“心血管病高危人群早期筛查与综合干预项目”[5],已进行10年的风险筛查和综合干预管理。目前内蒙古自治区针对于心血管病高危人群的综合干预效果评价研究匮乏,本研究旨在通过全面分析血脂、血糖、血压指标水平,评价内蒙古心血管病高危人群综合干预效果,为心血管病防控提供科学依据。
本研究基于心血管病早期筛查与综合干预项目[5],为前瞻性队列研究。采用多阶段分层抽样方法,选取2015—2024年内蒙古自治区6个项目点(呼和浩特市、乌海市、赤峰市、鄂尔多斯市、呼伦贝尔市、兴安盟)的15 346名心血管病高危人群进行基线调查。基线数据始于2015年,选取2016年、2020年、2024年3期随访数据。纳入标准:(1)35~75岁;(2)2015~2024年全程参与本项目的综合干预管理的心血管病高危人群;(3)自愿参加并签署知情同意书。排除标准:(1)动态退出队列的高危人群;(2)异常高值。按纳入排除标准最终纳入3 354名研究对象。项目已通过中国医学科学院阜外医院伦理委员会的伦理审批(15-070/997)。
使用国家心血管病中心设计的标准问卷进行人口学特征调查。所有调查员经统一培训合格后进行正式调查,内容包括年龄、性别、地区、文化程度、吸烟与饮酒习惯等信息。
包括身高、体重、血压测量,血脂和空腹血糖检测。使用欧姆龙HEM-7430型电子血压计对研究对象右侧肱动脉进行坐位血压测量,连续测量两次,并记录平均血压值[6]。空腹血糖(FPG)测量采用百捷BK6-20MD血糖检测仪,血清总胆固醇(TC)水平、高密度脂蛋白胆固醇(HDL-C)水平、甘油三酯(TG)水平、低密度脂蛋白胆固醇(LDL-C)水平检测采用Cardiocheck PA血脂检测仪。
(1)心血管病高危人群:符合以下内容中任一条件即可判定为高危,①心肌梗死病史、接受经皮冠状动脉介人治疗、接受冠状动脉搭桥手术或脑卒中病史;②平均收缩压>160 mmHg(1 mmHg=0.133 kpa)或舒张压>100 mmHg、低密度脂蛋白胆固醇≥4.14 mmol/、高密度脂蛋白胆固醇<0.78 mmol;③参照世界卫生组织在2008年颁布的《心血管风险评估和管理指南》中相关评估标准,预测筛查对象10年心血管病患病风险≥20%[7]。(2)血脂异常:符合下列任一条件者,被定义为患有血脂异常,①TC≥5.2 mmol/L,②HDL-C≤1.0mmol/L,③TG≥1.7 mmol/L,④LDL-C≥3.4 mmol/L[8]。(3)高血压:符合下列条件之一,则定义为高血压患者,①收缩压(SBP)≥140 mmHg(1 mmHg=0.133 kPa)和(或)舒张压(DBP)≥90 mmHg,②测量时,即使收缩压低于140 mmHg,舒张压低于90 mmHg,有高血压病史,正服用降压药(西药、中成药及中药)者,仍应被诊断为高血压[9]。(4)依据《中国2型糖尿病防治指南(2020年版)》,符合以下任一条件者可诊断为糖尿病:①出现糖尿病症状(多饮多食,多尿,体重减轻,皮肤瘙痒或视力模糊),且随机血糖水平≥11.1 mmol/L的患者,②空腹血糖水平≥7.0 mmol/L者,③葡萄糖负荷后2h血糖水平≥11.1 mmol/L者,④自述服用降糖药物(包括西药、中成药及中药)者[10]。(5)体质指数(BMI):BMI低于18.5 kg/m2为体重过轻,介于24.0~27.9 kg/m2之间为超重,28.0 kg/m2及以上为肥胖,介于18.5~23.9 kg/m2之间为正常。(6)吸烟:进行调查时,在过去12个月内,平均每天至少吸烟1支。(7)饮酒:进行调查时,过去的12个月内,每月至少饮酒1次。
针对高风险人群,根据其个体风险因素和疾病状况,实施针对性、个性化、综合性的干预措施。(1)一级预防:针对心血管疾病高危人群提供生活方式调整的建议,包括戒烟、限制饮酒、保持均衡饮食、减少脂肪摄入、控制体重以及进行适当的体力劳动和锻炼,有助于高危个体更好地了解疾病,增强自我保健意识,并提升其在预防保健方面的能力。(2)对于患有高血压、血脂异常、糖尿病或其他疾病的高危人群,将根据生活方式干预措施,提供个性化的血压、血脂和血糖控制建议。通过高危筛查被识别出疑似心血管疾病的个体,将被建议前往医院进行诊断和治疗。(3)三级预防:对于患有心血管疾病(包括冠心病、动脉粥样硬化、心肌梗死和中风)的高危人群,将提供个性化的药物治疗和康复建议,以缓解症状、预防疾病进展、改善预后、降低死亡率和残疾率,并预防疾病复发。
数据的整理和分析使用SPSS 25.0软件进行处理,正态分布的计量资料用采用描述,组间比较采用配对样本t检验和单因素方差分析。计数资料采用频数和百分比描述,组间比较采用卡方检验。双侧检验,检验水准 α=0.05。
共3 354名高危人群纳入研究,平均年龄为(56.57±8.04)岁,50~59岁年龄段占比最大(41.29%)。其中男性1 388人(41.38%),女性1 966人(58.62%),男女性别比为1:1.42。城市地区860人(25.64%),农村地区2 494人(74.36%)。初中及以下学历人群占比最大,2 453人(73.14%),其次是高中或中专学历人群602人(17.95%),大专及以上学历人群273人(8.14%),不清楚或拒绝回答人群26人(0.78%)。饮酒和吸烟人群分别为407人(12.13%)和745人(22.21%)。超重人群占比最大,1 510人(45.02%),其次是肥胖人群1 077人(32.11%),体质指数正常人群753人(22.45%),偏瘦人群14人(0.42%)。
研究结果显示,通过对心血管病高危人群进行10年的综合干预,TC和LDL-C水平有所下降,差异均有统计学意义(t=23.477,t=18.013,P<0.001);HDL-C和TG水平有所上升,差异均有统计学意义(t=-4.096,t=-9.154,P<0.001),不同人口特征之间的血脂水平差异有统计学意义(P<0.001)。详情见表1。
心血管病高危人群空腹血糖水平有所上升,差异有统计学意义(t=-14.725,P<0.001)。不同人口特征之间的空腹血糖水平均有统计学差异(P<0.001)。详情见表2。
心血管病高危人群收缩压经过10年的综合干预,从160.16±22.76 mmHg下降至140.98±18.65 mmHg,差异有统计学意义(t=49.481,P<0.001);舒张压从93.10±12.75 mmHg下降至84.89±10.94 mmHg,差异有统计学意义(t=38.451,P<0.001)。不同人口特征之间的SBP和DBP水平均有统计学意义(P<0.001)。详情见表3。
2015—2024年对心血管病高危人群进行综合干预,血脂和血压异常率均呈下降趋势,差异均有统计学意义(χ2=23.369,χ2=359.194,P<0.001);而空腹血糖异常率呈先下降后上升趋势,差异有统计学意义(χ2=357.752,P<0.001)。详情见表4。
本研究发现,通过对内蒙古心血管病高危人群进行10年的综合干预,其TC和LDL-C水平下降,与河南省的研究结果一致[11];但TG水平有所上升。报道显示,TC、LDL-C、TG变异性升高与多种心血管疾病相关[12]。研究表明,HDL-C为冠心病的保护因子[13],本研究结果显示HDL-C水平进行综合干预管理后上升。本文结果显示,空腹血糖水平通过干预管理并非达到理想水平。空腹血糖受损以肝脏胰岛素抵抗和过量内源性葡萄糖生成为特征[14],长期处于空腹血糖受损并进展为糖尿病,发生心血管病的风险更高[15]。Soltani等人的研究显示,SBP每降低5 mmHg,DBP每降低2 mmHg,分别有可能降低4%和9%的冠心病发病风险[16],而本文研究结果发现,通过综合干预管理后,心血管病高危人群SBP和DBP水分别下降了19.18 mmHg和8.21 mmHg,表明内蒙古心血管病高危人群综合干预管理措施可有效降低收缩压和舒张压,具有重要的公共卫生意义。本研究中,TC、HDL-C和LDL-C水平干预前后的变化幅度较小,这种微小变化对个体而言可能临床意义不大,但从公共卫生的角度来看,在大规模人群中广泛实施的干预措施,即使其对个体指标的影响微小,也可能通过人群归因风险原理产生巨大的群体健康收益。微小的平均变化意味着整体风险因素分布曲线的左移。从统计学角度看可能由以下两种原因:(1)效应量小但检验效能高,即使微小差异,大样本也能检测出统计学显著性。(2)测量精度高,使得微小变化达到显著。在资源有限的情况下,为推广成本效益优异的群体干预措施提供科学依据。需注意配合评估长期效果,避免“显著但无价值”的统计陷阱。
本研究进一步分析了心血管病高危人群“三高”综合干预效果,进行综合干预10年来,内蒙古心血管病高危人群血压异常率呈下降趋势,血脂异常率呈先下降后略上升,总体下降趋势。有报道显示,通过5年的心血管病高危人群综合干预,其高血压、高血糖、血脂异常比例均显著降低,高血压、高血糖、血脂异常的风险分别下降78.1%、74.3%和47.6%[17]。然而,本研究中发现通过综合干预后空腹血糖异常率呈先下降后上升趋势。空腹血糖异常率的升高,除疾病自然进展外,提示可能存在干预措施执行不到位情况。这种执行偏差的原因有待进一步研究。
本研究的优势在于通过10年的长期观察综合干预措施对“三高”水平的影响,捕捉“三高”水平的动态变化,但也存在一定的局限性:(1)研究是在心血管病高危人群中探讨“三高”水平变化,研究结果的外推人群有限;(2)队列研究的证明因果关系的证据强度弱于随机对照试验(RCT)。观察到的空腹血糖和TG水平略微升高究竟是干预的“副作用”,还是疾病自然进展、其他未控制因素或患者行为改变的结果,有待进一步分析研究。(3)由于动态退出人员较多,可能导致存在一定的选择偏倚。
综上所述,10年的综合干预管理对内蒙古心血管病高危人群具有降低TC、LDL-C、SBP、DBP的作用;针对内蒙古自治区心血管病高危人群多年的综合干预对血脂和血压的异常率的降低行之有效。但需要做好对TG和空腹血糖的监测工作,进一步探讨其对心血管病的影响。
  • 中央转移支付地方重大公共卫生项目中国心血管病高危人群早期筛查与干预项目(Z195110010004)
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2026年第53卷第2期
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doi: 10.20043/j.cnki.MPM.202506249
  • 接收时间:2025-06-16
  • 首发时间:2026-11-02
  • 出版时间:2026-01-25
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  • 收稿日期:2025-06-16
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中央转移支付地方重大公共卫生项目中国心血管病高危人群早期筛查与干预项目(Z195110010004)
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    1.内蒙古自治区疾病预防控制中心(内蒙古自治区预防医学科学院),内蒙古 呼和浩特 010080
    2.国家心血管病中心,中国医学科学院北京协和医学院阜外医院

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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
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