Article(id=1324078268919456093, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078175000605624, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202510029, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1759939200000, receivedDateStr=2025-10-09, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793614459494, onlineDateStr=2026-11-02, pubDate=1769270400000, pubDateStr=2026-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793614459494, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793614459494, creator=13701087609, updateTime=1793614459494, updator=13701087609, issue=Issue{id=1324078175000605624, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='2', pageStart='193', pageEnd='384', issueExtLink='null', onlineDate='null', pubDate='1769270400000', pubDateStr='2026-01-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793614437103, creator='13701087609', updateTime=1793614526046, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324078548130082942, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078175000605624, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324078548130082943, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324078175000605624, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=200, endPage=204, ext={EN=ArticleExt(id=1324078269129171294, articleId=1324078268919456093, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Analysis of the current status of knowledge,attitude,and practice regarding H.pylori infection prevention and control, and the influencing factors of practices among H.pylori-positive individuals in rural China, columnId=1228016567443718970, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods Advances, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the current status of knowledge, attitudes, and practices (KAP) and influencing factors of practices among Helicobacter pylori (H. pylori)-positive populations in rural China, and to provide a reference basis for adopting effective health education and health promotion strategies.
Methods From October to December 2024, a multistage stratified cluster random sampling method was employed to select 168 administrative villages (neighborhood committees) from 27 rural counties across four provinces (Jiangsu, Anhui, Shandong, and Henan) as the study areas. All rural residents underwent H. pylori infection testing via the 13C-urea breath test, and a questionnaire survey was conducted among 16 144 individuals who were identified as H. pylori-positive. Cluster analysis and Logistic regression were utilized to assess the current status of knowledge, attitudes, and practices (KAP) and to identify behavioral influencing factors among the H. pylori-positive population.
Results The standardized scores for the knowledge, attitude, and practice dimensions among the H. pylori-positive population were (0.69±0.29), (0.91±0.15), and (0.73±0.15) points, respectively. K-means cluster analysis revealed that 27.99%, 5.49%, and 15.59% of the surveyed participants exhibited low levels in the knowledge, attitude, and practice dimensions, respectively. Based on knowledge and attitude levels, the population was categorized into four distinct characteristic groups: high knowledge-high attitude, low knowledge-high attitude, high knowledge-low attitude, and low knowledge-low attitude. The multivariate analysis results indicated that compared to the low knowledge-low attitude level group, the high knowledge-high attitude level group had a higher behavioral dimension level (OR=6.45, 95% CI: 5.45-6.83), followed by the low knowledge-high attitude level group (OR=2.48, 95% CI: 2.09-2.95). Compared to males, females had a higher behavioral dimension level (OR=1.46, 95% CI: 1.33-1.60). Compared to farmers, non-farmer occupational groups had a higher behavioral dimension level (OR=1.30, 95% CI: 1.18-1.44).
Conclusion The H. pylori-positive population in rural areas demonstrates relatively positive attitudes but suboptimal knowledge and health practices. It is recommended to implement precise stratified intervention strategies tailored to different population characteristics. Emphasis should be placed on groups with low knowledge-low attitude and high knowledge-low attitude to enhance their cognitive levels and risk awareness. This approach provides evidence-based strategic support for the comprehensive prevention and control of H. pylori infection and gastric cancer in rural areas.
, authors=Xiang-yi RUI
1, Ya-rong HAN
2, Xin-yi YANG
1, Xue-fei FENG
1, yu-qi WANG
2, Ning WANG
1, Bao-hua WANG
1, authorsList=Xiang-yi RUI, Ya-rong HAN, Xin-yi YANG, Xue-fei FENG, yu-qi WANG, Ning WANG, Bao-hua WANG, authorCompany=null, correspAuthors=Bao-hua WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324078269817037153, articleId=1324078268919456093, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=农村幽门螺杆菌阳性人群对H.pylori感染防治知信行现状及行为影响因素分析, columnId=1228016567632462653, journalTitle=现代预防医学, columnName=流行病与统计方法, runingTitle=null, highlight=null, articleAbstract=
目的 探讨我国农村幽门螺杆菌(Helicobacter pylori,H.pylori)阳性人群H. pylori防治相关知识、态度、行为现状及行为影响因素,为采取有效的健康教育及健康促进策略提供参考。
方法 于2024年10月—12月,采用多阶段分层整群随机抽样法,选取江苏、安徽、山东和河南4省的27个农村县区的168个行政村(居委会),对全体农村居民采用13C尿素呼气试验进行H. pylori感染检测,对16 144名已确定为H. pylori阳性人群开展问卷调查。利用聚类分析确定H.pylori阳性人群知信行现状,并采用logistic回归分析H.pylori相关健康行为影响因素。
结果 H.pylori阳性人群的知识、态度、行为维度的标准分分别为(0.69±0.29)、(0.91±0.15)、(0.73±0.15)分。K-means聚类分析结果显示,27.99%、5.49%和15.59%的调查对象分别在知识、态度、行为维度处于低水平。根据知识和态度水平划分为高知识—高态度、低知识—高态度、高知识—低态度及低知识—低态度四类特征人群。多因素分析结果显示,与低知识—低态度水平的人群相比,高知识—高态度水平的人群行为维度水平高(OR=6.45,95% CI:5.45~6.83),其次是低知识—高态度水平的人群(OR=2.48,95% CI:2.09~2.95);与男性相比,女性的行为维度水平高(OR=1.46,95% CI:1.33~1.60);与农民相比,非农民职业的人群的行为维度水平高(OR=1.30,95% CI:1.18~1.44)。
结论 农村地区H. pylori阳性人群态度水平较高,但知识与健康行为水平偏低,建议对不同特征人群实施精准分层干预策略,重点针对低知识—低态度和高知识—低态度的人群,强化其认知水平及风险意识,为农村地区H.pylori感染及胃癌的综合防控提供循证策略支持。
, authors=芮向依
1, 韩亚蓉
2, 杨心仪
1, 冯雪菲
1, 王宇琦
2, 王宁
1, 王宝华
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芮向依(2001—),女,硕士在读,研究方向:肿瘤等慢性病预防与控制
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=1mVfJkuExEmJWf1TBKx3pw==, magXml=1DLKjouQf9++b4xr1/MZtg==, pdfUrl=null, pdf=g+aDezui48FLZfIv1CMmXA==, pdfFileSize=646818, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=FWfL91twRea4Jgd9pZmwJw==, mapNumber=null, fund=null)}, authors=[Author(id=1324078270353908072, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1324078270441988458, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, authorId=1324078270353908072, language=EN, stringName=Xiang-yi RUI, firstName=Xiang-yi, middleName=null, lastName=RUI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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37(1): 70-75. (In Chinese), articleTitle=Risk factors of oral Helicobacter pylori infection among children in two kindergartens in Suzhou and the effects of oral cleaning on reducing oral Helicobacter pylori infection, refAbstract=null)], funds=[Fund(id=1324078274200084890, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, awardId=2024YFC3607800, language=CN, fundingSource=国家重点研发计划(2024YFC3607800), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1324078270072889698, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, xref=1., ext=[AuthorCompanyExt(id=1324078270081278307, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, companyId=1324078270072889698, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China), AuthorCompanyExt(id=1324078270089666916, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, companyId=1324078270072889698, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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2.南通市疾病预防控制中心健康教育与慢性病防治科)])], figs=[ArticleFig(id=1324078273034068370, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=EN, label=Table 1, caption=
Basic characteristics of respondents(n=16 144)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 人数(n) | 构成比(%) |
|---|
| 年龄 | | |
| 18~40岁(青年) | 3 842 | 23.80 |
| 41~60岁(中年) | 7 502 | 46.47 |
| ≥61岁(老年) | 4 800 | 29.73 |
| 性别 | | |
| 男 | 6 799 | 42.11 |
| 女 | 9 345 | 57.89 |
| 文化程度 | | |
| 初中及以下 | 11 630 | 72.04 |
| 高中或中专 | 2 245 | 13.91 |
| 大专及以上 | 2 269 | 14.05 |
| 职业 | | |
| 农民 | 7 947 | 49.23 |
| 其他 | 8 197 | 50.77 |
| 婚姻状况 | | |
| 已婚/同居 | 14 709 | 91.11 |
| 其他(未婚/丧偶/离婚/分居) | 1 435 | 8.89 |
), ArticleFig(id=1324078273185063315, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=CN, label=表1, caption=
调查对象一般情况(n=16 144)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 人数(n) | 构成比(%) |
|---|
| 年龄 | | |
| 18~40岁(青年) | 3 842 | 23.80 |
| 41~60岁(中年) | 7 502 | 46.47 |
| ≥61岁(老年) | 4 800 | 29.73 |
| 性别 | | |
| 男 | 6 799 | 42.11 |
| 女 | 9 345 | 57.89 |
| 文化程度 | | |
| 初中及以下 | 11 630 | 72.04 |
| 高中或中专 | 2 245 | 13.91 |
| 大专及以上 | 2 269 | 14.05 |
| 职业 | | |
| 农民 | 7 947 | 49.23 |
| 其他 | 8 197 | 50.77 |
| 婚姻状况 | | |
| 已婚/同居 | 14 709 | 91.11 |
| 其他(未婚/丧偶/离婚/分居) | 1 435 | 8.89 |
), ArticleFig(id=1324078273281532308, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=EN, label=Table 2, caption=
Scores and classification criteria of the H.pylori KAP questionnaire
, figureFileSmall=null, figureFileBig=null, tableContent=
| 项目 | 得分范围 | 问卷得分(分) | 程度划分[例(%)] |
|---|
| 总分 | 标准分 | 高 | 低 |
|---|
| 知识维度 | 0~27 | 18.66±7.74 | 0.69±0.29 | 11 626(72.01) | 4 518(27.99) |
| H.pylori一般知识 | 0~9 | 6.01±3.00 | 0.67±0.33 | | |
| H.pylori传染性知识 | 0~4 | 2.19±1.80 | 0.55±0.45 | | |
| H.pylori诊断与治疗知识 | 0~7 | 5.01±2.03 | 0.72±0.29 | | |
| H.pylori预防知识 | 0~7 | 5.44±2.08 | 0.78±0.30 | | |
| 态度维度 | 5~50 | 46.11±6.85 | 0.91±0.15 | 15 258(94.51) | 886(5.49) |
| 胃部出现不适症状,愿意去医院检测H.pylori | 1~10 | 9.03±2.07 | 0.89±0.23 | | |
| 愿意听从医生建议进行药物治疗 | 1~10 | 9.38±1.56 | 0.93±0.17 | | |
| 对自己能按时按量服药有多大的信心 | 1~10 | 9.11±1.86 | 0.90±0.21 | | |
| 愿意在体检项目中增加H.pylori 检测 | 1~10 | 9.23±1.84 | 0.91±0.20 | | |
| 愿意接受H.pylori 相关知识的宣教 | 1~10 | 9.35±1.63 | 0.93±0.18 | | |
| 行为维度 | 7~32 | 25.14±3.67 | 0.73±0.15 | 13 627(84.41) | 2 517(15.59) |
| 用药行为 | 0~6 | 4.38±1.53 | 0.73±0.26 | | |
| 就餐行为 | 2~14 | 10.64±1.91 | 0.72±0.16 | | |
| 日常行为 | 0~12 | 10.12±1.87 | 0.84±0.16 | | |
), ArticleFig(id=1324078273386389909, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=CN, label=表2, caption=
H.pylori知信行问卷得分情况及程度划分
, figureFileSmall=null, figureFileBig=null, tableContent=
| 项目 | 得分范围 | 问卷得分(分) | 程度划分[例(%)] |
|---|
| 总分 | 标准分 | 高 | 低 |
|---|
| 知识维度 | 0~27 | 18.66±7.74 | 0.69±0.29 | 11 626(72.01) | 4 518(27.99) |
| H.pylori一般知识 | 0~9 | 6.01±3.00 | 0.67±0.33 | | |
| H.pylori传染性知识 | 0~4 | 2.19±1.80 | 0.55±0.45 | | |
| H.pylori诊断与治疗知识 | 0~7 | 5.01±2.03 | 0.72±0.29 | | |
| H.pylori预防知识 | 0~7 | 5.44±2.08 | 0.78±0.30 | | |
| 态度维度 | 5~50 | 46.11±6.85 | 0.91±0.15 | 15 258(94.51) | 886(5.49) |
| 胃部出现不适症状,愿意去医院检测H.pylori | 1~10 | 9.03±2.07 | 0.89±0.23 | | |
| 愿意听从医生建议进行药物治疗 | 1~10 | 9.38±1.56 | 0.93±0.17 | | |
| 对自己能按时按量服药有多大的信心 | 1~10 | 9.11±1.86 | 0.90±0.21 | | |
| 愿意在体检项目中增加H.pylori 检测 | 1~10 | 9.23±1.84 | 0.91±0.20 | | |
| 愿意接受H.pylori 相关知识的宣教 | 1~10 | 9.35±1.63 | 0.93±0.18 | | |
| 行为维度 | 7~32 | 25.14±3.67 | 0.73±0.15 | 13 627(84.41) | 2 517(15.59) |
| 用药行为 | 0~6 | 4.38±1.53 | 0.73±0.26 | | |
| 就餐行为 | 2~14 | 10.64±1.91 | 0.72±0.16 | | |
| 日常行为 | 0~12 | 10.12±1.87 | 0.84±0.16 | | |
), ArticleFig(id=1324078273583522198, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=EN, label=Table 3, caption=
Current status of the H.pylori Knowledge-Attitude dimension (n=16 144)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 人数 (n) | 构成比 (%) | χ2值 | P值 |
|---|
| 知识—态度维度 | | | 996.31 | <0.001 |
| 低—低 | 658 | 4.08 | | |
| 低—高 | 3 860 | 23.91 | | |
| 高—低 | 228 | 1.41 | | |
| 高—高 | 11 398 | 70.60 | | |
), ArticleFig(id=1324078273814208919, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=CN, label=表3, caption=
H.pylori知识—态度维度现状(n=16 144)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 人数 (n) | 构成比 (%) | χ2值 | P值 |
|---|
| 知识—态度维度 | | | 996.31 | <0.001 |
| 低—低 | 658 | 4.08 | | |
| 低—高 | 3 860 | 23.91 | | |
| 高—低 | 228 | 1.41 | | |
| 高—高 | 11 398 | 70.60 | | |
), ArticleFig(id=1324078274023924120, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=EN, label=Table 4, caption=
Univariate and multivariate analysis of practices factors influencing H.pylori-infection (n=16 144)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 单因素分析 | 多因素分析 |
|---|
| OR值(95%CI) | P值 | OR值(95%CI) | P值 |
|---|
| 性别 | | | | |
| 男 | Ref. | - | Ref. | - |
| 女 | 1.41(1.30~1.54) | <0.001 | 1.46(1.33~1.60) | <0.001 |
| 年龄 | | | | |
| 18~40岁(青年) | Ref. | - | - | - |
| 41~60岁(中年) | 0.83(0.74~0.93) | 0.001 | - | - |
| ≥61岁(老年) | 0.59(0.52~0.66) | <0.001 | - | - |
| 文化程度 | | | | |
| 初中及以下 | Ref. | - | | |
| 高中或中专 | 1.40(1.23~1.60) | <0.001 | - | - |
| 大专及以上 | 1.67(1.45~1.92) | <0.001 | - | - |
| 职业 | | | | |
| 农民 | Ref. | - | Ref. | - |
| 其他 | 1.58(1.45~1.72) | <0.001 | 1.30(1.18~1.44) | <0.001 |
| 婚姻状况 | | | | |
| 已婚/同居 | Ref. | - | - | - |
| 其他(未婚/丧偶/离婚/分居) | 1.03(0.88~1.20) | 0.721 | - | - |
| 知识-态度维度水平 | | | | |
| 低-低 | Ref. | - | Ref. | - |
| 高-高 | 6.74(5.72~7.95) | <0.001 | 6.45(5.45~6.83) | <0.001 |
| 高-低 | 1.40(1.03~1.92) | 0.033 | 1.34(0.98~1.83) | 0.071 |
| 低-高 | 2.41(2.03~2.86) | <0.001 | 2.48(2.09~2.95) | <0.001 |
), ArticleFig(id=1324078274103615897, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324078268919456093, language=CN, label=表4, caption=
H.pylori感染行为影响因素的单因素和多因素分析(n=16 144)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 单因素分析 | 多因素分析 |
|---|
| OR值(95%CI) | P值 | OR值(95%CI) | P值 |
|---|
| 性别 | | | | |
| 男 | Ref. | - | Ref. | - |
| 女 | 1.41(1.30~1.54) | <0.001 | 1.46(1.33~1.60) | <0.001 |
| 年龄 | | | | |
| 18~40岁(青年) | Ref. | - | - | - |
| 41~60岁(中年) | 0.83(0.74~0.93) | 0.001 | - | - |
| ≥61岁(老年) | 0.59(0.52~0.66) | <0.001 | - | - |
| 文化程度 | | | | |
| 初中及以下 | Ref. | - | | |
| 高中或中专 | 1.40(1.23~1.60) | <0.001 | - | - |
| 大专及以上 | 1.67(1.45~1.92) | <0.001 | - | - |
| 职业 | | | | |
| 农民 | Ref. | - | Ref. | - |
| 其他 | 1.58(1.45~1.72) | <0.001 | 1.30(1.18~1.44) | <0.001 |
| 婚姻状况 | | | | |
| 已婚/同居 | Ref. | - | - | - |
| 其他(未婚/丧偶/离婚/分居) | 1.03(0.88~1.20) | 0.721 | - | - |
| 知识-态度维度水平 | | | | |
| 低-低 | Ref. | - | Ref. | - |
| 高-高 | 6.74(5.72~7.95) | <0.001 | 6.45(5.45~6.83) | <0.001 |
| 高-低 | 1.40(1.03~1.92) | 0.033 | 1.34(0.98~1.83) | 0.071 |
| 低-高 | 2.41(2.03~2.86) | <0.001 | 2.48(2.09~2.95) | <0.001 |
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