Article(id=1324077912021926905, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324077716676424398, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202510262, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1760371200000, receivedDateStr=2025-10-14, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793614374404, onlineDateStr=2026-11-02, pubDate=1773072000000, pubDateStr=2026-03-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793614374404, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793614374404, creator=13701087609, updateTime=1793614374404, updator=13701087609, issue=Issue{id=1324077716676424398, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='5', pageStart='769', pageEnd='960', issueExtLink='null', onlineDate='null', pubDate='1773072000000', pubDateStr='2026-03-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793614327830, creator='13701087609', updateTime=1793614418028, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324078095132655884, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324077716676424398, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324078095132655885, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324077716676424398, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=941, endPage=946, ext={EN=ArticleExt(id=1324077913888392186, articleId=1324077912021926905, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Multi-pathogen surveillance results among 7 244 cases of acute respiratory infection in Qinghai Province, columnId=1228016573156360233, journalTitle=Modern Preventive Medicine, columnName=Disease Control and Prevention, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the detection of 22 respiratory pathogens among 7 244 acute respiratory infection (ARI)cases in Qinghai Province during 2024—2025, characterize their epidemiological patterns, and provide evidence for local prevention and control.
Methods From February 2024 to August 2025, 7 244 ARI specimens were collected from six sentinel hospitals in five prefectures of Qinghai. Multiplex real-time PCR was used to detect 22 respiratory pathogens, and statistical analyses were performed using SPSS 28.0.
Results The overall positive rate for the 22 pathogens was 52.32%. The five most frequently detected pathogens were Haemophilus influenzae (33.02%), Streptococcus pneumoniae (26.99%), influenza A virus(10.48%), rhinovirus (9.40%), and SARS-CoV-2 (7.10%). Among 3 790 positive specimens, 60.82% were single infections and 39.18 % were mixed infections. The positive rate in influenza-like illness (ILI) cases (55.73%) was higher than in severe acute respiratory infection (SARI) cases (45.94%), and both the single infection rate (χ2=12.231, P<0.001) and the multiple infection rate (χ2=33.674, P<0.001) differed significantly between ILI and SARI cases. Pathogen detection rates varied across six age groups among ARI cases, peaking in children aged 4-7 years (68.06%) and lowest in adults ≥60 years (39.34%).
Conclusion ARI in Qinghai Province shows a clear winter-spring peak. Haemophilus influenzae, Streptococcus pneumoniae, influenza A virus, rhinovirus, and SARS-CoV-2 are the predominant pathogens, and mixed infections are common. Detection rates of the 22 pathogens vary by age, season, and region. Therefore, targeted prevention and control measures should be implemented for key populations in different seasons.
, authors=Chao-cai WANG
1, Yan LIU
2, Li-li XU
1, Shi-hua CHAO
1, Yu-fen HU
1, authorsList=Chao-cai WANG, Yan LIU, Li-li XU, Shi-hua CHAO, Yu-fen HU, authorCompany=null, correspAuthors=Li-li XU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324077916274951163, articleId=1324077912021926905, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=青海省7 244例急性呼吸道感染病例的呼吸道多病原监测结果分析, columnId=1228016573844226129, journalTitle=现代预防医学, columnName=疾病预防控制, runingTitle=null, highlight=null, articleAbstract=
目的 统计2024—2025年青海省7 244例急性呼吸道感染（acute respiratory infection,ARI）病例22种呼吸道病原体检出情况，分析呼吸道感染病原体流行特征，为我省呼吸道传染病防控提供科学依据。
方法 采用多重real-time 聚合酶链式反应方法，对2024年2月— 2025年8月在青海省5个市（州）的6家呼吸道多病原监测哨点医院采集的7 244份 ARI 病例标本进行22种呼吸道病原体的检测，检测结果采用SPSS 28.0软件进行统计分析。
结果 22种病原体核酸检测总阳性率为52.32%。阳性率排名前五位的分别是流感嗜血杆菌（33.02%）、肺炎链球菌（26.99%）、甲型流感（10.48%）、鼻病毒（9.40%）和新型冠状病毒（7.10%）。3 790份阳性标本中，单一感染占60.82%，混合感染占39.18%。流感样病例（influenza-like illness，ILI）病原体阳性率为55.73%，高于重症急性呼吸道感染（severe acute respiratory infection，SARI）病例的45.94%，ILI和SARI病例病原体单一感染（χ2=12.231，P<0.001）和多重感染率差异有统计学意义（χ2= 33.674，P<0.001）。ARI病例6个年龄组感染22种病原体的感染率不同，4～7岁病例阳性率最高，为68.06%，60岁及以上病例最低，为39.34%。
结论 青海省呼吸道感染冬春季节高发，流感嗜血杆菌、肺炎链球菌、甲型流感、鼻病毒和新型冠状病毒为呼吸道感染的主要病原体，混合感染普遍存在。22种病原体检出率与年龄、季节、地区有关，需在不同季节，针对重点人群开展防控措施。
, authors=王朝才
1, 刘燕
2, 徐莉立
1, 巢世花
1, 胡玉凤
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王朝才 (1980—)，男，硕士，副主任医师，研究方向：传染病防控工作
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点，除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=Y13EPeOF27IjFmXDCKRBOw==, magXml=5uSboSEP3dkJCyW4A+r/gw==, pdfUrl=null, pdf=P9x7YvbS795ChOsfvAxwCg==, pdfFileSize=612687, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=NfC0WJPwZJU1lLmCFTsFoA==, mapNumber=null, fund=null)}, authors=[Author(id=1324077918355324929, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1324077918439211011, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, authorId=1324077918355324929, language=EN, stringName=Chao-cai WANG, firstName=Chao-cai, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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56(2): 103-107. (In Chinese), articleTitle=Consideration on implementation of co-administration of Seasonal Influenza and COVID-19 vaccines during pandemic in China, refAbstract=null)], funds=[Fund(id=1324077925196234795, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, awardId=〔2025〕10号, language=CN, fundingSource=青海省昆仑英才·高层次卫生健康人才项目(〔2025〕10号), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1324077916547580924, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, xref=1., ext=[AuthorCompanyExt(id=1324077916560163837, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, companyId=1324077916547580924, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Qinghai Provincial Center for Disease Control and Prevention, Xining, Qinghai 810000, China), AuthorCompanyExt(id=1324077916568552446, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, companyId=1324077916547580924, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.青海省疾病预防控制中心，青海 西宁 810000)]), AuthorCompany(id=1324077918263051263, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, xref=2., ext=[AuthorCompanyExt(id=1324077918271439872, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, companyId=1324077918263051263, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.青海大学)])], figs=[ArticleFig(id=1324077924445454371, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=EN, label=Table 1, caption=
Basic characteristics of 7 244 ARI cases in Qinghai Province
, figureFileSmall=null, figureFileBig=null, tableContent=
| 分类 | | 病例数 | 构成比(%) |
|---|
| 地区 | 西宁市 | 2 631 | 36.33 |
| 海东市 | 1 134 | 15.65 |
| 海南州 | 1 170 | 16.15 |
| 海西州 | 1 183 | 16.33 |
| 玉树州 | 1 126 | 15.54 |
| 年龄(岁) | 0～<4 | 1 708 | 23.58 |
| 4～<7 | 865 | 11.94 |
| 7～<12 | 698 | 9.64 |
| 12～<18 | 399 | 5.51 |
| 18～<60 | 2 248 | 31.03 |
| ≥60 | 1 326 | 18.30 |
| 性别 | 男 | 3 724 | 51.41 |
| 女 | 3 520 | 48.59 |
| 病例类别 | 门急诊 | 4 717 | 65.12 |
| 住院 | 2 527 | 34.88 |
), ArticleFig(id=1324077924529340452, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=CN, label=表1, caption=
青海省7 244例ARI病例基本信息
, figureFileSmall=null, figureFileBig=null, tableContent=
| 分类 | | 病例数 | 构成比(%) |
|---|
| 地区 | 西宁市 | 2 631 | 36.33 |
| 海东市 | 1 134 | 15.65 |
| 海南州 | 1 170 | 16.15 |
| 海西州 | 1 183 | 16.33 |
| 玉树州 | 1 126 | 15.54 |
| 年龄(岁) | 0～<4 | 1 708 | 23.58 |
| 4～<7 | 865 | 11.94 |
| 7～<12 | 698 | 9.64 |
| 12～<18 | 399 | 5.51 |
| 18～<60 | 2 248 | 31.03 |
| ≥60 | 1 326 | 18.30 |
| 性别 | 男 | 3 724 | 51.41 |
| 女 | 3 520 | 48.59 |
| 病例类别 | 门急诊 | 4 717 | 65.12 |
| 住院 | 2 527 | 34.88 |
), ArticleFig(id=1324077924609032229, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=EN, label=Table 2, caption=
Detection of 22 pathogens in specimens from 7 244 ARI cases in Qinghai Province ［n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 单一感染 | 双重感染 | 三重感染 | 四重感染 | ≥五重感染 | 合计 |
|---|
| 新型冠状病毒 | 366(5.05） | 105(1.45） | 35(0.48） | 4(0.06) | 4(0.06) | 514(7.10) |
| 甲型流感 | 533（7.36） | 165(2.28) | 52(0.72) | 8(0.11) | 1(0.01) | 759(10.48) |
| 乙型流感 | 10（0.14） | 2(0.03) | 0(0.00) | 0(0.00) | 0(0.00) | 12(0.17) |
| 呼吸道合胞病毒 | 146（2.02） | 52(0.72) | 23(0.32) | 5(0.07) | 1(0.01) | 227(3.13) |
| 腺病毒 | 228（3.15） | 73(1.01) | 32(0.44) | 14(0.19) | 7(0.10) | 354(4.89) |
| 人偏肺病毒 | 146（2.02） | 43(0.59) | 28(0.39) | 8(0.11) | 2(0.03) | 227(3.13) |
| 副流感病毒 | 82（1.13） | 34(0.47) | 14(0.19) | 4(0.06) | 2(0.03) | 136(1.88) |
| 普通冠状病毒 | 65（0.90） | 23(0.32) | 11(0.15) | 4(0.06) | 2(0.03) | 105(1.45) |
| 博卡病毒 | 27（0.37） | 10(0.14) | 9(0.12) | 3(0.04) | 1(0.01) | 50(0.69) |
| 鼻病毒 | 403（5.56） | 144(1.99) | 92(1.27) | 28(0.39) | 14(0.19) | 681(9.40) |
| 肠道病毒 | 173（2.39） | 62(0.86) | 42(0.58) | 14(0.19) | 8(0.11) | 299(4.13) |
| 肺炎支原体 | 277（3.82） | 87(1.20) | 46(0.64) | 15(0.21) | 7(0.10) | 432(5.96) |
| A族链球菌 | 205（2.83） | 69(0.95) | 32(0.44) | 20(0.28) | 8(0.11) | 334(4.61) |
| 百日咳鲍特菌 | 96(1.33) | 35(0.48) | 27(0.37) | 5(0.07) | 8(0.11) | 171(2.36) |
| 肺炎链球菌 | 1 182(16.32) | 471(6.50) | 225(3.11) | 55(0.76) | 22(0.30) | 1 955(26.99) |
| 流感嗜血杆菌 | 1 460(20.15) | 605(8.35) | 248(3.42) | 59(0.81) | 20(0.28) | 2 392(33.02) |
| 军团菌 | 36(0.50) | 12(0.17) | 7(0.10) | 6(0.08) | 2(0.03) | 63(0.87) |
| 肺炎克雷伯菌 | 214(2.95) | 65(0.90) | 40(0.55) | 17(0.23) | 7(0.10) | 343(4.73) |
| 曲霉菌 | 81(1.12) | 22(0.30) | 17(0.23) | 9(0.12) | 2(0.03) | 131(1.81) |
| 隐球菌 | 8(0.11) | 1(0.01) | 2(0.03) | 0(0.00) | 3(0.04) | 14(0.19) |
| 鹦鹉热衣原体 | 10(0.14) | 1(0.01) | 1(0.01) | 2(0.03) | 2(0.03) | 16(0.22) |
| 肺炎衣原体 | 83(1.15) | 33(0.46) | 19(0.26) | 4(0.06) | 3(0.04) | 142(1.96) |
| 合计 | 2 305(31.82) | 1 057(14.59) | 334(4.61) | 71(0.98) | 23(0.32) | 3 790（52.32） |
), ArticleFig(id=1324077924701306918, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=CN, label=表2, caption=
青海省7 244例 ARI病例标本中22种病原体检出情况［n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 单一感染 | 双重感染 | 三重感染 | 四重感染 | ≥五重感染 | 合计 |
|---|
| 新型冠状病毒 | 366(5.05） | 105(1.45） | 35(0.48） | 4(0.06) | 4(0.06) | 514(7.10) |
| 甲型流感 | 533（7.36） | 165(2.28) | 52(0.72) | 8(0.11) | 1(0.01) | 759(10.48) |
| 乙型流感 | 10（0.14） | 2(0.03) | 0(0.00) | 0(0.00) | 0(0.00) | 12(0.17) |
| 呼吸道合胞病毒 | 146（2.02） | 52(0.72) | 23(0.32) | 5(0.07) | 1(0.01) | 227(3.13) |
| 腺病毒 | 228（3.15） | 73(1.01) | 32(0.44) | 14(0.19) | 7(0.10) | 354(4.89) |
| 人偏肺病毒 | 146（2.02） | 43(0.59) | 28(0.39) | 8(0.11) | 2(0.03) | 227(3.13) |
| 副流感病毒 | 82（1.13） | 34(0.47) | 14(0.19) | 4(0.06) | 2(0.03) | 136(1.88) |
| 普通冠状病毒 | 65（0.90） | 23(0.32) | 11(0.15) | 4(0.06) | 2(0.03) | 105(1.45) |
| 博卡病毒 | 27（0.37） | 10(0.14) | 9(0.12) | 3(0.04) | 1(0.01) | 50(0.69) |
| 鼻病毒 | 403（5.56） | 144(1.99) | 92(1.27) | 28(0.39) | 14(0.19) | 681(9.40) |
| 肠道病毒 | 173（2.39） | 62(0.86) | 42(0.58) | 14(0.19) | 8(0.11) | 299(4.13) |
| 肺炎支原体 | 277（3.82） | 87(1.20) | 46(0.64) | 15(0.21) | 7(0.10) | 432(5.96) |
| A族链球菌 | 205（2.83） | 69(0.95) | 32(0.44) | 20(0.28) | 8(0.11) | 334(4.61) |
| 百日咳鲍特菌 | 96(1.33) | 35(0.48) | 27(0.37) | 5(0.07) | 8(0.11) | 171(2.36) |
| 肺炎链球菌 | 1 182(16.32) | 471(6.50) | 225(3.11) | 55(0.76) | 22(0.30) | 1 955(26.99) |
| 流感嗜血杆菌 | 1 460(20.15) | 605(8.35) | 248(3.42) | 59(0.81) | 20(0.28) | 2 392(33.02) |
| 军团菌 | 36(0.50) | 12(0.17) | 7(0.10) | 6(0.08) | 2(0.03) | 63(0.87) |
| 肺炎克雷伯菌 | 214(2.95) | 65(0.90) | 40(0.55) | 17(0.23) | 7(0.10) | 343(4.73) |
| 曲霉菌 | 81(1.12) | 22(0.30) | 17(0.23) | 9(0.12) | 2(0.03) | 131(1.81) |
| 隐球菌 | 8(0.11) | 1(0.01) | 2(0.03) | 0(0.00) | 3(0.04) | 14(0.19) |
| 鹦鹉热衣原体 | 10(0.14) | 1(0.01) | 1(0.01) | 2(0.03) | 2(0.03) | 16(0.22) |
| 肺炎衣原体 | 83(1.15) | 33(0.46) | 19(0.26) | 4(0.06) | 3(0.04) | 142(1.96) |
| 合计 | 2 305(31.82) | 1 057(14.59) | 334(4.61) | 71(0.98) | 23(0.32) | 3 790（52.32） |
), ArticleFig(id=1324077924814553127, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=EN, label=Table 3, caption=
Comparison of pathogen detection between ILI and SARI cases ［n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 呼吸道病原体 | 总病例数（n=7244） | ILI(n=4717) | SARI(n=2527) | χ2 值 | P 值 |
|---|
| 单一感染 | 2 305 | 1 567(33.22) | 738(29.20) | 12.231 | <0.001 |
| 多重感染 | 1 485 | 1 062(22.51) | 423(16.74) | 33.674 | <0.001 |
| 新型冠状病毒 | 366 | 267(5.66) | 99(3.92) | 10.417 | <0.001 |
| 甲型流感 | 533 | 408(8.65) | 125(4.95) | 33.101 | <0.001 |
| 乙型流感 | 10 | 8(0.17) | 2(0.08) | 0.431 | 0.512 |
| 呼吸道合胞病毒 | 146 | 101(2.14) | 45(1.78) | 1.082 | 0.298 |
| 腺病毒 | 228 | 177(3.75) | 51(2.02) | 16.234 | <0.001 |
| 人偏肺病毒 | 146 | 103(2.18) | 43(1.70) | 1.936 | 0.164 |
| 副流感病毒 | 82 | 50(1.06) | 32(1.27) | 0.626 | 0.429 |
| 普通冠状病毒 | 65 | 45(0.95) | 20(0.79) | 0.489 | 0.484 |
| 博卡病毒 | 27 | 17(0.36) | 10(0.40) | 0.055 | 0.814 |
| 鼻病毒 | 403 | 295(6.25) | 108(4.27) | 12.280 | <0.001 |
| 肠道病毒 | 173 | 137(2.90) | 36(1.42) | 15.457 | <0.001 |
| 肺炎支原体 | 277 | 151(3.20) | 126(4.99) | 14.255 | <0.001 |
| A族链球菌 | 205 | 144(3.05) | 61(2.41) | 2.442 | 0.118 |
| 百日咳鲍特菌 | 96 | 67(1.42) | 29(1.15) | 0.936 | 0.333 |
| 肺炎链球菌 | 1 182 | 837(17.74) | 345(13.65) | 20.176 | <0.001 |
| 流感嗜血杆菌 | 1 460 | 1 020(21.62) | 440(17.41) | 552.790 | <0.001 |
| 军团菌 | 36 | 16(0.34) | 20(0.79) | 6.806 | 0.009 |
| 肺炎克雷伯菌 | 214 | 134(2.84) | 80(3.17) | 0.606 | 0.436 |
| 曲霉菌 | 81 | 53(1.12) | 28(1.11) | 0.004 | 0.952 |
| 隐球菌 | 8 | 6(0.13) | 2(0.08) | 0.344 | 0.557 |
| 鹦鹉热衣原体 | 10 | 7(0.15) | 3(0.12) | 0.000 | 1.000 |
| 肺炎衣原体 | 83 | 50(1.06) | 33(1.31) | 0.878 | 0.349 |
| 合计 | 3 790 | 2 629(55.73) | 1 161(45.94) | 63.230 | <0.001 |
), ArticleFig(id=1324077924890050600, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=CN, label=表3, caption=
ILI和SARI病例病原体检出情况比较［n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 呼吸道病原体 | 总病例数（n=7244） | ILI(n=4717) | SARI(n=2527) | χ2 值 | P 值 |
|---|
| 单一感染 | 2 305 | 1 567(33.22) | 738(29.20) | 12.231 | <0.001 |
| 多重感染 | 1 485 | 1 062(22.51) | 423(16.74) | 33.674 | <0.001 |
| 新型冠状病毒 | 366 | 267(5.66) | 99(3.92) | 10.417 | <0.001 |
| 甲型流感 | 533 | 408(8.65) | 125(4.95) | 33.101 | <0.001 |
| 乙型流感 | 10 | 8(0.17) | 2(0.08) | 0.431 | 0.512 |
| 呼吸道合胞病毒 | 146 | 101(2.14) | 45(1.78) | 1.082 | 0.298 |
| 腺病毒 | 228 | 177(3.75) | 51(2.02) | 16.234 | <0.001 |
| 人偏肺病毒 | 146 | 103(2.18) | 43(1.70) | 1.936 | 0.164 |
| 副流感病毒 | 82 | 50(1.06) | 32(1.27) | 0.626 | 0.429 |
| 普通冠状病毒 | 65 | 45(0.95) | 20(0.79) | 0.489 | 0.484 |
| 博卡病毒 | 27 | 17(0.36) | 10(0.40) | 0.055 | 0.814 |
| 鼻病毒 | 403 | 295(6.25) | 108(4.27) | 12.280 | <0.001 |
| 肠道病毒 | 173 | 137(2.90) | 36(1.42) | 15.457 | <0.001 |
| 肺炎支原体 | 277 | 151(3.20) | 126(4.99) | 14.255 | <0.001 |
| A族链球菌 | 205 | 144(3.05) | 61(2.41) | 2.442 | 0.118 |
| 百日咳鲍特菌 | 96 | 67(1.42) | 29(1.15) | 0.936 | 0.333 |
| 肺炎链球菌 | 1 182 | 837(17.74) | 345(13.65) | 20.176 | <0.001 |
| 流感嗜血杆菌 | 1 460 | 1 020(21.62) | 440(17.41) | 552.790 | <0.001 |
| 军团菌 | 36 | 16(0.34) | 20(0.79) | 6.806 | 0.009 |
| 肺炎克雷伯菌 | 214 | 134(2.84) | 80(3.17) | 0.606 | 0.436 |
| 曲霉菌 | 81 | 53(1.12) | 28(1.11) | 0.004 | 0.952 |
| 隐球菌 | 8 | 6(0.13) | 2(0.08) | 0.344 | 0.557 |
| 鹦鹉热衣原体 | 10 | 7(0.15) | 3(0.12) | 0.000 | 1.000 |
| 肺炎衣原体 | 83 | 50(1.06) | 33(1.31) | 0.878 | 0.349 |
| 合计 | 3 790 | 2 629(55.73) | 1 161(45.94) | 63.230 | <0.001 |
), ArticleFig(id=1324077924965548073, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=EN, label=Table 4, caption=
Age distribution of pathogens among 7 244 ARI cases in Qinghai Province ［n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 年龄组 | χ2 值 | P值 |
|---|
0～<4岁
(n=1 714) | 4～<7岁
(n=864) | 7～<12岁
(n=697) | 12～<18岁
(n=398) | 18～<60岁
(n=2 244) | ≥60岁
(n=1 327) |
|---|
| 新型冠状病毒 | 126(7.35) | 33(3.82)a | 36(5.16) | 16(4.02) | 112(4.99)a | 43(3.24)a | 31.622 | <0.001 |
| 甲型流感 | 138(8.35) | 82(9.49) | 51(7.32) | 36(9.05) | 143(6.37)b | 83(6.25) | 14.032 | 0.015 |
| 乙型流感 | 6(0.35) | 2(0.23) | 2(0.29) | 0(0.00) | 0(0.00) | 0(0.00) | — | 0.009* |
| 呼吸道合胞病毒 | 76(4.43) | 30(3.47) | 7(1.00)ab | 4(1.01)a | 14(0.62)ab | 15(1.13)ab | 92.989 | <0.001 |
| 腺病毒 | 76(4.43) | 59(6.83) | 57(8.18)a | 13(3.27)c | 16(0.71)abcd | 7(0.53)abcd | 196.841 | <0.001 |
| 人偏肺病毒 | 41(2.39) | 31(3.59) | 15(2.15) | 2(0.50)b | 32(1.43)b | 25(1.88) | 20.421 | 0.001 |
| 副流感病毒 | 32(1.87) | 24(2.78) | 3(0.43)b | 1(0.25)b | 11(0.49)ab | 11(0.83)b | 41.273 | <0.001 |
| 普通冠状病毒 | 27(1.58) | 12(1.39) | 3(0.43) | 1(0.25) | 14(0.62)a | 8(0.60) | 17.964 | 0.003 |
| 博卡病毒 | 15(0.88) | 6(0.69) | 2(0.29) | 1(0.25) | 2(0.09)a | 1(0.08)a | — | <0.001* |
| 鼻病毒 | 140(8.17) | 86(9.95) | 54(7.75) | 40(10.05) | 56(2.50)abcd | 27(2.03)abcd | 147.062 | <0.001 |
| 肠道病毒 | 55(3.21) | 48(5.56) | 19(2.73) | 7(1.76)b | 35(1.56)ab | 9(0.68)abc | 66.404 | <0.001 |
| 肺炎支原体 | 49(2.86) | 49(5.67)a | 72(10.33)ab | 25(6.28)a | 49(2.18)bcd | 33(2.49)bcd | 121.987 | <0.001 |
| A族链球菌 | 19(1.11) | 36(4.17)a | 50(7.17)a | 17(4.27)a | 63(2.81)ac | 19(1.43)bcd | 87.564 | <0.001 |
| 百日咳鲍特菌 | 24(1.40) | 9(1.04) | 15(2.15) | 11(2.76) | 31(1.38) | 5(0.38)cd | 21.105 | 0.001 |
| 肺炎链球菌 | 351(20.48) | 169(19.56) | 111(15.93) | 67(16.83) | 335(14.93)ab | 148(11.15)abcde | 57.586 | <0.001 |
| 流感嗜血杆菌 | 376(21.94) | 257(29.75) | 204(29.27) | 114(28.64) | 337(15.02) | 172(12.96) | 186.024 | <0.001 |
| 军团菌 | 17(0.99) | 4(0.46) | 4(0.57) | 2(0.50) | 4(0.18)a | 4(0.30) | — | 0.009* |
| 肺炎克雷伯菌 | 30(1.75) | 16(1.85) | 10(1.43) | 12(3.02) | 80(3.57)a | 65(4.90)abc | 37.350 | <0.001 |
| 曲霉菌 | 16(0.93) | 7(0.81) | 4(0.57) | 7(1.76) | 33(1.47) | 13(0.98) | 6.511 | 0.260 |
| 隐球菌 | 0(0.00) | 0(0.00) | 0(0.00) | 1(0.25) | 4(0.18) | 2(0.15) | — | 0.255* |
| 鹦鹉热衣原体 | 0(0.00) | 2(0.23) | 1(0.14) | 1(0.25) | 2(0.09) | 3(0.23) | — | 0.123* |
| 肺炎衣原体 | 13(0.76) | 8(0.93) | 14(2.01) | 19(4.77)ab | 25(1.11)d | 4(0.30)cd | 61.846 | <0.001 |
| 合计 | 996(58.11) | 588(68.06)a | 462(66.28)a | 247(62.06) | 974(43.40)abcd | 522(39.34)abcd | 339.562 | <0.001 |
), ArticleFig(id=1324077925049434154, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324077912021926905, language=CN, label=表4, caption=
青海省7 244例ARI病例不同病原体年龄分布［n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 年龄组 | χ2 值 | P值 |
|---|
0～<4岁
(n=1 714) | 4～<7岁
(n=864) | 7～<12岁
(n=697) | 12～<18岁
(n=398) | 18～<60岁
(n=2 244) | ≥60岁
(n=1 327) |
|---|
| 新型冠状病毒 | 126(7.35) | 33(3.82)a | 36(5.16) | 16(4.02) | 112(4.99)a | 43(3.24)a | 31.622 | <0.001 |
| 甲型流感 | 138(8.35) | 82(9.49) | 51(7.32) | 36(9.05) | 143(6.37)b | 83(6.25) | 14.032 | 0.015 |
| 乙型流感 | 6(0.35) | 2(0.23) | 2(0.29) | 0(0.00) | 0(0.00) | 0(0.00) | — | 0.009* |
| 呼吸道合胞病毒 | 76(4.43) | 30(3.47) | 7(1.00)ab | 4(1.01)a | 14(0.62)ab | 15(1.13)ab | 92.989 | <0.001 |
| 腺病毒 | 76(4.43) | 59(6.83) | 57(8.18)a | 13(3.27)c | 16(0.71)abcd | 7(0.53)abcd | 196.841 | <0.001 |
| 人偏肺病毒 | 41(2.39) | 31(3.59) | 15(2.15) | 2(0.50)b | 32(1.43)b | 25(1.88) | 20.421 | 0.001 |
| 副流感病毒 | 32(1.87) | 24(2.78) | 3(0.43)b | 1(0.25)b | 11(0.49)ab | 11(0.83)b | 41.273 | <0.001 |
| 普通冠状病毒 | 27(1.58) | 12(1.39) | 3(0.43) | 1(0.25) | 14(0.62)a | 8(0.60) | 17.964 | 0.003 |
| 博卡病毒 | 15(0.88) | 6(0.69) | 2(0.29) | 1(0.25) | 2(0.09)a | 1(0.08)a | — | <0.001* |
| 鼻病毒 | 140(8.17) | 86(9.95) | 54(7.75) | 40(10.05) | 56(2.50)abcd | 27(2.03)abcd | 147.062 | <0.001 |
| 肠道病毒 | 55(3.21) | 48(5.56) | 19(2.73) | 7(1.76)b | 35(1.56)ab | 9(0.68)abc | 66.404 | <0.001 |
| 肺炎支原体 | 49(2.86) | 49(5.67)a | 72(10.33)ab | 25(6.28)a | 49(2.18)bcd | 33(2.49)bcd | 121.987 | <0.001 |
| A族链球菌 | 19(1.11) | 36(4.17)a | 50(7.17)a | 17(4.27)a | 63(2.81)ac | 19(1.43)bcd | 87.564 | <0.001 |
| 百日咳鲍特菌 | 24(1.40) | 9(1.04) | 15(2.15) | 11(2.76) | 31(1.38) | 5(0.38)cd | 21.105 | 0.001 |
| 肺炎链球菌 | 351(20.48) | 169(19.56) | 111(15.93) | 67(16.83) | 335(14.93)ab | 148(11.15)abcde | 57.586 | <0.001 |
| 流感嗜血杆菌 | 376(21.94) | 257(29.75) | 204(29.27) | 114(28.64) | 337(15.02) | 172(12.96) | 186.024 | <0.001 |
| 军团菌 | 17(0.99) | 4(0.46) | 4(0.57) | 2(0.50) | 4(0.18)a | 4(0.30) | — | 0.009* |
| 肺炎克雷伯菌 | 30(1.75) | 16(1.85) | 10(1.43) | 12(3.02) | 80(3.57)a | 65(4.90)abc | 37.350 | <0.001 |
| 曲霉菌 | 16(0.93) | 7(0.81) | 4(0.57) | 7(1.76) | 33(1.47) | 13(0.98) | 6.511 | 0.260 |
| 隐球菌 | 0(0.00) | 0(0.00) | 0(0.00) | 1(0.25) | 4(0.18) | 2(0.15) | — | 0.255* |
| 鹦鹉热衣原体 | 0(0.00) | 2(0.23) | 1(0.14) | 1(0.25) | 2(0.09) | 3(0.23) | — | 0.123* |
| 肺炎衣原体 | 13(0.76) | 8(0.93) | 14(2.01) | 19(4.77)ab | 25(1.11)d | 4(0.30)cd | 61.846 | <0.001 |
| 合计 | 996(58.11) | 588(68.06)a | 462(66.28)a | 247(62.06) | 974(43.40)abcd | 522(39.34)abcd | 339.562 | <0.001 |
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