Article(id=1322608110196339221, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1322608013010120712, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202506066, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1749139200000, receivedDateStr=2025-06-06, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793263946340, onlineDateStr=2026-10-29, pubDate=1762704000000, pubDateStr=2025-11-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793263946340, onlineIssueDateStr=2026-10-29, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793263946340, creator=13701087609, updateTime=1793263946340, updator=13701087609, issue=Issue{id=1322608013010120712, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='21', pageStart='3841', pageEnd='4032', issueExtLink='null', onlineDate='null', pubDate='1762704000000', pubDateStr='2025-11-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793263923169, creator='13701087609', updateTime=1793264266929, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322609454932149086, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1322608013010120712, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322609454932149087, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1322608013010120712, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3872, endPage=3878, ext={EN=ArticleExt(id=1322608110447997462, articleId=1322608110196339221, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Association between relative fat mass and arthritis in a middle-aged and elderly Chinese population, columnId=1240413921954295836, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods, runingTitle=null, highlight=null, articleAbstract=
Objective The aim of this study was to investigate the association between relative fat mass (RFM) and the risk of arthritis in middle-aged and elderly Chinese adults.
Methods A cross-sectional analysis was performed using 2011 CHARLS data and included a total of 12 921 participants, including 6 144 males (47.55%) and 6 777 females (52.45%), with a mean age of (59.49 ± 9.60) years. Multivariable logistic regression and restricted cubic splines (RCS) were used to analyze the cross-sectional association between RFM and arthritis. A total of 8 350 middle-aged and elderly people who were not diagnosed with arthritis in the 2011 cross-sectional study were included in the longitudinal study and followed up until 2018. Kaplan-Meier curves, multivariable Cox proportional hazards regression models, and RCS were used to analyze the longitudinal association between different baseline RFM levels and the risk of incident arthritis in 2011. Meanwhile, the consistency of this association in different population subgroups was assessed by subgroup analysis, and sensitivity analysis was used to verify the stability of the model results.
Results In the cross-sectional study, multivariable logistic regression analysis showed that higher RFM was associated with an increased risk of arthritis after adjusting for confounders (OR=1.02, 95% CI: 1.02-1.03). Middle-aged and older adults in the Q3 (OR=1.30, 95% CI: 1.15-1.48) and Q4 (OR=1.60, 95% CI: 1.40-1.82) groups had a higher risk of arthritis compared with the first quartile (Q1). In the longitudinal study, a total of 916 individuals were first diagnosed with arthritis during the follow-up period. Multivariable Cox regression analysis showed that higher RFM was associated with an increased risk of incident arthritis after adjusting for confounders (HR=1.02, 95% CI: 1.02-1.04). The risk of incident arthritis was significantly higher in the Q4 group(HR=1.56, 95% CI:1.23-1.98) compared with Q1. Subgroup analysis showed no significant interactions between RFM and each subgroup variable. The results of the sensitivity analysis were generally consistent with the conclusions of the primary analysis. ROC curves showed that RFM had a better diagnostic efficacy for arthritis than obesity indicators such as BMI.
Conclusion Higher levels of RFM are associated with an increased risk of arthritis in the middle-aged and elderly Chinese population, paying attention to RFM levels may help in the early identification of populations at risk for arthritis, providing new insights for disease prevention and intervention.
, authors=Hui-zhi XUE
1, Hui-long CHEN
1, Nan YAO
2, Wei-ju LI
1, 2, Yu-tong ZHANG
1, Zheng-hui KONG
1, Yu-wei LIU
1, Zhao-hui LV
2, authorsList=Hui-zhi XUE, Hui-long CHEN, Nan YAO, Wei-ju LI, Yu-tong ZHANG, Zheng-hui KONG, Yu-wei LIU, Zhao-hui LV, authorCompany=null, correspAuthors=Zhao-hui LV, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322608114084459050, articleId=1322608110196339221, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=中国中老年人群相对脂肪量与关节炎的关联研究, columnId=1228016567632462653, journalTitle=现代预防医学, columnName=流行病与统计方法, runingTitle=null, highlight=null, articleAbstract=
目的 本研究旨在探讨相对脂肪量（relative fat mass，RFM）与中国中老年人关节炎风险之间的关联。
方法 使用2011年中国健康与养老追踪调查（China Health and Retirement Longitudinal Study，CHARLS）数据进行横断面分析，共纳入12 921名参与者，其中男性6 144名（47.55%），女性6 777名（52.45%），平均年龄（59.49±9.60）岁。采用多因素logistic回归和限制立方样条（restricted cubic splines，RCS）分析RFM与关节炎之间的横断面关联。将2011年横断面研究中8 350名未被诊断为关节炎的中老年人纳入纵向研究，随访至2018年。采用Kaplan-Meier曲线、多因素Cox比例风险回归模型和RCS分析2011年不同基线RFM水平与新发关节炎风险之间的纵向关联。同时，通过亚组分析评估该关联在不同人群亚组中的一致性，并利用敏感性分析验证模型结果的稳定性。
结果 在横断面研究中，多因素logistic回归分析显示，在调整混杂因素后，较高的RFM与关节炎风险增加相关（OR=1.02，95% CI：1.02～1.03），与第一个四分位数（Q1）相比，Q3（OR=1.30，95% CI：1.15～1.48）和Q4（OR=1.60，95% CI：1.40～1.82）组中老年人具有更高的关节炎风险。在纵向研究中，随访期间共916人被首次诊断为关节炎。多因素Cox回归分析显示，在调整混杂因素后，较高的RFM与新发关节炎风险增加相关（HR=1.02，95% CI：1.02～1.04），与Q1相比，Q4（HR=1.56，95% CI：1.23～1.98）组的新发关节炎风险显著高于Q1组。亚组分析显示，RFM与各亚组变量之间均未表现出显著的交互作用。敏感性分析的结果与主要分析结论基本一致。构建受试者工作特征曲线（receiver operating characteristic curve，ROC）显示，相较BMI等肥胖指标，RFM对关节炎有更好的诊断效能。
结论 在中国中老年人群中，较高水平的RFM与关节炎发病风险增加有关，关注RFM水平可能有助于早期识别关节炎风险人群，为疾病的预防和干预提供新的思路。
, authors=薛慧芝
1, 陈慧龙
1, 姚楠
2, 李伟举
1, 2, 章雨童
1, 孔政辉
1, 刘育伟
1, 吕朝晖
2, authorsList=薛慧芝, 陈慧龙, 姚楠, 李伟举, 章雨童, 孔政辉, 刘育伟, 吕朝晖, authorCompany=null, correspAuthors=吕朝晖, authorNote=
薛慧芝（2000—），女，硕士在读，研究方向：中西医结合防治骨关节炎
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点，除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=7Dwup6cMzkAJ+w1MgByGHA==, magXml=ITFNuKtiBc7HovD1QyYYaw==, pdfUrl=null, pdf=RFMVVcl40fhl3avwAL0+Og==, pdfFileSize=1253966, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=BpK0YviumIwkk5h0grOlmA==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=CFT2Qro9cbH5ytOqffvWqg==, mapNumber=null, fund=null)}, authors=[Author(id=1322608114457752113, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322608114533249587, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, authorId=1322608114457752113, language=EN, stringName=Hui-zhi XUE, firstName=Hui-zhi, middleName=null, lastName=XUE, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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薛慧芝（2000—），女，硕士在读，研究方向：中西医结合防治骨关节炎
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356: 323-328., articleTitle=The relationship between depression and relative fat mass（RFM）: A population-based study, refAbstract=null)], funds=[Fund(id=1322608119960679029, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, awardId=2025A1515010409, language=CN, fundingSource=广东省基础与应用基础研究基金项目(2025A1515010409), fundOrder=null, country=null), Fund(id=1322608120031982198, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, awardId=20251020; 20221023, language=CN, fundingSource=广东省中医药局科研项目(20251020; 20221023), fundOrder=null, country=null), Fund(id=1322608120090702455, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, awardId=SEZYY2023A08, language=CN, fundingSource=广东省第二中医院科研创新基金项目(SEZYY2023A08), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1322608114298368555, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, xref=1., ext=[AuthorCompanyExt(id=1322608114306757164, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, companyId=1322608114298368555, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=The Fifth Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, China), AuthorCompanyExt(id=1322608114315145773, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, companyId=1322608114298368555, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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2.广东省第二中医院，广东 广州 510095)])], figs=[ArticleFig(id=1322608118442340961, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Figure 1, caption=
Flowchart of participants selection, figureFileSmall=s8w7eS2wGRl0UNJwjxRUkQ==, figureFileBig=BpK0YviumIwkk5h0grOlmA==, tableContent=null), ArticleFig(id=1322608118505255522, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=图1, caption=
调查对象纳入流程图, figureFileSmall=s8w7eS2wGRl0UNJwjxRUkQ==, figureFileBig=BpK0YviumIwkk5h0grOlmA==, tableContent=null), ArticleFig(id=1322608118702387811, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Figure 2, caption=
Dose-response relationship between RFM and arthritis risk, figureFileSmall=T42p0IBA/1zsoJcyl5Jodw==, figureFileBig=3t1DUaYP9S4u+xZZf15cMA==, tableContent=null), ArticleFig(id=1322608118752719460, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=图2, caption=
RFM与关节炎风险的剂量-反应关系, figureFileSmall=T42p0IBA/1zsoJcyl5Jodw==, figureFileBig=3t1DUaYP9S4u+xZZf15cMA==, tableContent=null), ArticleFig(id=1322608118819828325, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Figure 3, caption=
Comparison of the cumulative incidence of incident arthritis across RFM levels, figureFileSmall=6d+o1V3H6otpglOGFfi18w==, figureFileBig=5CHcq6Se50OgplHxgk64nw==, tableContent=null), ArticleFig(id=1322608118891131494, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=图3, caption=
RFM与新发关节炎的累积发生率比较, figureFileSmall=6d+o1V3H6otpglOGFfi18w==, figureFileBig=5CHcq6Se50OgplHxgk64nw==, tableContent=null), ArticleFig(id=1322608118954046055, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Figure 4, caption=
Dose-response relationship between RFM and incident arthritis risk, figureFileSmall=1l0S1HkM+ufTseW32U8Ojw==, figureFileBig=bL1+Hd6XOx3aDHaBZBDvYA==, tableContent=null), ArticleFig(id=1322608119021154920, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=图4, caption=
RFM与新发关节炎风险的剂量-反应关系, figureFileSmall=1l0S1HkM+ufTseW32U8Ojw==, figureFileBig=bL1+Hd6XOx3aDHaBZBDvYA==, tableContent=null), ArticleFig(id=1322608119084069481, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Figure 5, caption=
Subgroup analyses of the association between RFM and incident arthritis risk, figureFileSmall=PMs/BYUJ1w9ZMPUtLh3DrA==, figureFileBig=2ai2oNl4HYHfu5QuxODpRA==, tableContent=null), ArticleFig(id=1322608119146984042, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=图5, caption=
RFM与新发关节炎风险关联的亚组分析, figureFileSmall=PMs/BYUJ1w9ZMPUtLh3DrA==, figureFileBig=2ai2oNl4HYHfu5QuxODpRA==, tableContent=null), ArticleFig(id=1322608119218287211, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Figure 6, caption=
Analysis of the diagnostic efficiency of RFM, BMI,WC, and WHtR for arthritis, figureFileSmall=FD/1FxMn3YqHuFsPYIxSzw==, figureFileBig=KyVY0ywiAmy9H3O1Va6DyA==, tableContent=null), ArticleFig(id=1322608119293784684, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=图6, caption=
RFM、BMI、腰围、腰高比对关节炎的诊断效能分析注：WC为腰围。
, figureFileSmall=FD/1FxMn3YqHuFsPYIxSzw==, figureFileBig=KyVY0ywiAmy9H3O1Va6DyA==, tableContent=null), ArticleFig(id=1322608119356699245, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Table 1, caption=
Comparison of baseline characteristics between arthritis and non-arthritis populations in 2011［（
），n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 总体 (n=12 921) | 无关节炎组 (n=8 350) | 关节炎组(n=4 571) | t/χ2值 | P值 |
|---|
| 年龄（岁） | 59.49±9.60 | 59.10±9.78 | 60.20±9.23 | -6.34 | <0.001 |
| RFM | 32.73±8.64 | 32.11±8.54 | 33.87±8.70 | -11.15 | <0.001 |
| BMI（kg/m2） | 23.46±3.90 | 23.40±3.88 | 23.57±3.94 | -2.22 | 0.026 |
| 身高（cm） | 158.11±8.63 | 158.96±8.60 | 156.56±8.46 | 15.23 | <0.001 |
| 体重（kg） | 58.84±11.71 | 59.32±11.75 | 57.94±11.58 | 6.41 | <0.001 |
| 腰围（cm） | 85.30±10.18 | 85.24±10.07 | 85.42±10.38 | -0.96 | 0.336 |
| 性别 | | | | 109.89 | <0.001 |
| 女性 | 6 777 (52.45) | 4 095 (49.04) | 2 682 (58.67) | | |
| 男性 | 6 144 (47.55) | 4 255 (50.96) | 1 889 (41.33) | | |
| 婚姻情况 | | | | 5.89 | 0.015 |
| 已婚并与配偶同居 | 11 210 (86.76) | 7 289 (87.29) | 3 921 (85.78) | | |
| 未婚/分居/丧偶 | 1 711 (13.24) | 1 061 (12.71) | 650 (14.22) | | |
| 文化程度 | | | | 153.62 | <0.001 |
| 高中及以上 | 1 385 (10.72) | 1 047 (12.54) | 338 (7.39) | | |
| 中学 | 2 612 (20.22) | 1 833 (21.95) | 779 (17.04) | | |
| 小学 | 5 271 (40.79) | 3 264 (39.09) | 2 007 (43.91) | | |
| 文盲 | 3 653 (28.27) | 2 206 (26.42) | 1 447 (31.66) | | |
| 居住地 | | | | 1.00 | 0.317 |
| 农村 | 1 485 (11.49) | 977 (11.70) | 508 (11.11) | | |
| 城市 | 11 436 (88.51) | 7 373 (88.30) | 4 063 (88.89) | | |
| BMI分类 | | | | 5.35 | 0.069 |
| 正常范围 | 6 839 (52.93) | 4 482 (53.68) | 2 357 (51.56) | | |
| 超重及肥胖 | 5 189 (40.16) | 3 297 (39.49) | 1 892 (41.39) | | |
| 体重过轻 | 893 (6.91) | 571 (6.84) | 322 (7.04) | | |
| 吸烟 | | | | 37.14 | <0.001 |
| 无 | 7 753 (60.00) | 4 848 (58.06) | 2 905 (63.55) | | |
| 有 | 5 168 (40.00) | 3 502 (41.94) | 1 666 (36.45) | | |
| 饮酒 | | | | 10.88 | <0.001 |
| 无 | 9 720 (75.23) | 6 204 (74.30) | 3 516 (76.92) | | |
| 有 | 3 201 (24.77) | 2 146 (25.70) | 1 055 (23.08) | | |
| 糖尿病 | | | | 13.69 | <0.001 |
| 无 | 11 284 (87.33) | 7 359 (88.13) | 3 925 (85.87) | | |
| 有 | 1 637 (12.67) | 991 (11.87) | 646 (14.13) | | |
| 高血压 | | | | 3.81 | 0.051 |
| 无 | 7 734 (59.86) | 5 050 (60.48) | 2 684 (58.72) | | |
| 有 | 5 187 (40.14) | 3 300 (39.52) | 1 887 (41.28) | | |
| 血脂异常 | | | | 7.34 | 0.007 |
| 无 | 8 116 (62.81) | 5 316 (63.66) | 2 800 (61.26) | | |
| 有 | 4 805 (37.19) | 3 034 (36.34) | 1 771 (38.74) | | |
), ArticleFig(id=1322608119428002414, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=表1, caption=
2011年关节炎人群与非关节炎人群基线特征对比［（
），n（%）］
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 总体 (n=12 921) | 无关节炎组 (n=8 350) | 关节炎组(n=4 571) | t/χ2值 | P值 |
|---|
| 年龄（岁） | 59.49±9.60 | 59.10±9.78 | 60.20±9.23 | -6.34 | <0.001 |
| RFM | 32.73±8.64 | 32.11±8.54 | 33.87±8.70 | -11.15 | <0.001 |
| BMI（kg/m2） | 23.46±3.90 | 23.40±3.88 | 23.57±3.94 | -2.22 | 0.026 |
| 身高（cm） | 158.11±8.63 | 158.96±8.60 | 156.56±8.46 | 15.23 | <0.001 |
| 体重（kg） | 58.84±11.71 | 59.32±11.75 | 57.94±11.58 | 6.41 | <0.001 |
| 腰围（cm） | 85.30±10.18 | 85.24±10.07 | 85.42±10.38 | -0.96 | 0.336 |
| 性别 | | | | 109.89 | <0.001 |
| 女性 | 6 777 (52.45) | 4 095 (49.04) | 2 682 (58.67) | | |
| 男性 | 6 144 (47.55) | 4 255 (50.96) | 1 889 (41.33) | | |
| 婚姻情况 | | | | 5.89 | 0.015 |
| 已婚并与配偶同居 | 11 210 (86.76) | 7 289 (87.29) | 3 921 (85.78) | | |
| 未婚/分居/丧偶 | 1 711 (13.24) | 1 061 (12.71) | 650 (14.22) | | |
| 文化程度 | | | | 153.62 | <0.001 |
| 高中及以上 | 1 385 (10.72) | 1 047 (12.54) | 338 (7.39) | | |
| 中学 | 2 612 (20.22) | 1 833 (21.95) | 779 (17.04) | | |
| 小学 | 5 271 (40.79) | 3 264 (39.09) | 2 007 (43.91) | | |
| 文盲 | 3 653 (28.27) | 2 206 (26.42) | 1 447 (31.66) | | |
| 居住地 | | | | 1.00 | 0.317 |
| 农村 | 1 485 (11.49) | 977 (11.70) | 508 (11.11) | | |
| 城市 | 11 436 (88.51) | 7 373 (88.30) | 4 063 (88.89) | | |
| BMI分类 | | | | 5.35 | 0.069 |
| 正常范围 | 6 839 (52.93) | 4 482 (53.68) | 2 357 (51.56) | | |
| 超重及肥胖 | 5 189 (40.16) | 3 297 (39.49) | 1 892 (41.39) | | |
| 体重过轻 | 893 (6.91) | 571 (6.84) | 322 (7.04) | | |
| 吸烟 | | | | 37.14 | <0.001 |
| 无 | 7 753 (60.00) | 4 848 (58.06) | 2 905 (63.55) | | |
| 有 | 5 168 (40.00) | 3 502 (41.94) | 1 666 (36.45) | | |
| 饮酒 | | | | 10.88 | <0.001 |
| 无 | 9 720 (75.23) | 6 204 (74.30) | 3 516 (76.92) | | |
| 有 | 3 201 (24.77) | 2 146 (25.70) | 1 055 (23.08) | | |
| 糖尿病 | | | | 13.69 | <0.001 |
| 无 | 11 284 (87.33) | 7 359 (88.13) | 3 925 (85.87) | | |
| 有 | 1 637 (12.67) | 991 (11.87) | 646 (14.13) | | |
| 高血压 | | | | 3.81 | 0.051 |
| 无 | 7 734 (59.86) | 5 050 (60.48) | 2 684 (58.72) | | |
| 有 | 5 187 (40.14) | 3 300 (39.52) | 1 887 (41.28) | | |
| 血脂异常 | | | | 7.34 | 0.007 |
| 无 | 8 116 (62.81) | 5 316 (63.66) | 2 800 (61.26) | | |
| 有 | 4 805 (37.19) | 3 034 (36.34) | 1 771 (38.74) | | |
), ArticleFig(id=1322608119499305583, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Table 2, caption=
Association between RFM and arthritis risk based on multivariable logistic regression analysis
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 模型1 | 模型2 | 模型3 |
|---|
| OR (95% CI) | P值 | OR (95% CI) | P值 | OR (95% CI) | P值 |
|---|
| RFM | 1.02 (1.02～1.03) | <0.001 | 1.02 (1.02～1.03) | <0.001 | 1.02 (1.02～1.03) | <0.001 |
| RFM Q | | | | | | |
| Q1 | (Reference) | | (Reference) | | (Reference) | |
| Q2 | 1.02 (0.91～1.13) | 0.782 | 1.05 (0.94～1.16) | 0.394 | 1.04 (0.93～1.16) | 0.512 |
| Q3 | 1.29 (1.16～1.43) | <0.001 | 1.30 (1.17～1.45) | <0.001 | 1.30 (1.15～1.48) | <0.001 |
| Q4 | 1.67 (1.50～1.85) | <0.001 | 1.61 (1.45～1.79) | <0.001 | 1.60 (1.40～1.82) | <0.001 |
), ArticleFig(id=1322608119570608752, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=表2, caption=
基于多因素logistic回归模型分析RFM与关节炎风险的关联
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 模型1 | 模型2 | 模型3 |
|---|
| OR (95% CI) | P值 | OR (95% CI) | P值 | OR (95% CI) | P值 |
|---|
| RFM | 1.02 (1.02～1.03) | <0.001 | 1.02 (1.02～1.03) | <0.001 | 1.02 (1.02～1.03) | <0.001 |
| RFM Q | | | | | | |
| Q1 | (Reference) | | (Reference) | | (Reference) | |
| Q2 | 1.02 (0.91～1.13) | 0.782 | 1.05 (0.94～1.16) | 0.394 | 1.04 (0.93～1.16) | 0.512 |
| Q3 | 1.29 (1.16～1.43) | <0.001 | 1.30 (1.17～1.45) | <0.001 | 1.30 (1.15～1.48) | <0.001 |
| Q4 | 1.67 (1.50～1.85) | <0.001 | 1.61 (1.45～1.79) | <0.001 | 1.60 (1.40～1.82) | <0.001 |
), ArticleFig(id=1322608119637717617, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Table 3, caption=
Association between RFM and incident arthritis risk based on multivariable Cox regression analysis
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 模型1 | 模型2 | 模型3 |
|---|
| OR (95% CI) | P值 | OR (95% CI) | P值 | OR (95% CI) | P值 |
|---|
| RFM | 1.03 (1.02～1.03) | <0.001 | 1.03 (1.02～1.03) | <0.001 | 1.02 (1.01～1.04) | <0.001 |
| RFM Q | | | | | | |
| Q1 | (Reference) | | (Reference) | | (Reference) | |
| Q2 | 1.14 (0.94～1.40) | 0.185 | 1.15 (0.94～1.41) | 0.165 | 1.09 (0.89～ 1.33) | 0.428 |
| Q3 | 1.28 (1.05～1.55) | 0.013 | 1.29 (1.06～1.57) | 0.013 | 1.26 (1.00～1.59) | 0.052 |
| Q4 | 1.70 (1.41～2.04) | <0.001 | 1.68 (1.38～2.03) | <0.001 | 1.56 (1.23～1.98) | <0.001 |
), ArticleFig(id=1322608119709020786, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=表3, caption=
基于多因素COX回归模型分析RFM对新发关节炎风险的影响
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 模型1 | 模型2 | 模型3 |
|---|
| OR (95% CI) | P值 | OR (95% CI) | P值 | OR (95% CI) | P值 |
|---|
| RFM | 1.03 (1.02～1.03) | <0.001 | 1.03 (1.02～1.03) | <0.001 | 1.02 (1.01～1.04) | <0.001 |
| RFM Q | | | | | | |
| Q1 | (Reference) | | (Reference) | | (Reference) | |
| Q2 | 1.14 (0.94～1.40) | 0.185 | 1.15 (0.94～1.41) | 0.165 | 1.09 (0.89～ 1.33) | 0.428 |
| Q3 | 1.28 (1.05～1.55) | 0.013 | 1.29 (1.06～1.57) | 0.013 | 1.26 (1.00～1.59) | 0.052 |
| Q4 | 1.70 (1.41～2.04) | <0.001 | 1.68 (1.38～2.03) | <0.001 | 1.56 (1.23～1.98) | <0.001 |
), ArticleFig(id=1322608119780323955, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=EN, label=Table 4, caption=
Sensitivity analyses of RFM and incident arthritis risk
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 模型1 | 模型2 | 模型3 |
|---|
| HR (95% CI) | P值 | HR (95% CI) | P值 | HR (95% CI) | P值 |
|---|
| RFM | 1.03(1.02～1.04) | <0.001 | 1.03(1.02～1.04) | <0.001 | 1.03(1.02～1.04) | <0.001 |
| RFM Q | | | | | | |
| Q1 | (Reference) | | (Reference) | | (Reference) | |
| Q2 | 1.19(0.92～1.55) | 0.179 | 1.19(0.92～1.54) | 0.193 | 1.09(0.84～1.42) | 0.507 |
| Q3 | 1.35(1.05～1.73) | 0.020 | 1.45(1.12～1.87) | 0.005 | 1.45(1.07～1.95) | 0.015 |
| Q4 | 1.88(1.48～2.38) | <0.001 | 1.93(1.51～2.47) | <0.001 | 1.81(1.33～2.46) | <0.001 |
), ArticleFig(id=1322608119864210036, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1322608110196339221, language=CN, label=表4, caption=
RFM与新发关节炎风险的敏感性分析结果
, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 模型1 | 模型2 | 模型3 |
|---|
| HR (95% CI) | P值 | HR (95% CI) | P值 | HR (95% CI) | P值 |
|---|
| RFM | 1.03(1.02～1.04) | <0.001 | 1.03(1.02～1.04) | <0.001 | 1.03(1.02～1.04) | <0.001 |
| RFM Q | | | | | | |
| Q1 | (Reference) | | (Reference) | | (Reference) | |
| Q2 | 1.19(0.92～1.55) | 0.179 | 1.19(0.92～1.54) | 0.193 | 1.09(0.84～1.42) | 0.507 |
| Q3 | 1.35(1.05～1.73) | 0.020 | 1.45(1.12～1.87) | 0.005 | 1.45(1.07～1.95) | 0.015 |
| Q4 | 1.88(1.48～2.38) | <0.001 | 1.93(1.51～2.47) | <0.001 | 1.81(1.33～2.46) | <0.001 |
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