Article(id=1241675635962212607, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241675628051755031, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202406232, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1718553600000, receivedDateStr=2024-06-17, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773968140831, onlineDateStr=2026-03-20, pubDate=1732464000000, pubDateStr=2024-11-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773968140831, onlineIssueDateStr=2026-03-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773968140831, creator=13701087609, updateTime=1773968140831, updator=13701087609, issue=Issue{id=1241675628051755031, tenantId=1146029695717560320, journalId=1227665162245664772, year='2024', volume='51', issue='22', pageStart='4033', pageEnd='4224', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773968138945, creator=13701087609, updateTime=1773968595676, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241677543783322543, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241675628051755031, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241677543783322544, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241675628051755031, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=4033, endPage=4037, ext={EN=ArticleExt(id=1241675636356477215, articleId=1241675635962212607, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=A longitudinal correlation study between cognitive function and activities of daily living in rural elderly, Guizhou, columnId=1228016567443718970, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods Advances, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the longitudinal correlation between cognitive function (CF) and activities of daily living (ADL) of the rural elderly in Guizhou province, and to provide theoretical basis for preventing and controlling health problems of the elderly.
Methods The multi-stage cluster random sampling method was used to select the elderly aged 60 years and above from 12 villages in 2 counties(districts) of Guizhou Province as the research objects. In this study, 792 elderly people who participated in two surveys in 2019 (T1) and 2022 (T2) and were ≥60 years old at baseline with complete variable values were selected as survey subjects. The cross-lagged model was used to investigate the longitudinal relationship between cognitive function and ADL.
Results The cross-lagged model showed that T1 ADL could predict T2 cognitive function after controlling T1 cognitive function (β= -0.120, P<0.001). After controlling for T1 ADL, T1 cognitive function predicted T2 ADL (β= -0.099, P=0.005). In the study of the association between two dimensions of ADL and cognitive function, it was found that T1 IADL could predict T2 cognitive function after controlling for T1 cognitive function (β= -0.138, P<0.001). Similarly, after controlling T1 IADL, T1 cognitive function could predict T2 IADL (β= -0.124, P<0.001). But there was no predictive effect between BADL and cognitive function.
Conclusion There is a longitudinal bidirectional correlation between cognitive function and activities of daily living of the rural elderly in Guizhou, only between IADL and cognitive function, suggesting that strengthening the monitoring and intervention of cognitive function of the elderly can help reducing the risk of the decline of IADL in the elderly, and strengthening the training of IADL plays an important role in delaying cognitive decline.
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目的 探讨贵州农村老年人认知功能(Cognitive Function,CF)与日常生活能力(Activities of Daily Living,ADL)是否存在纵向相互关联,为预防和控制农村老年人健康问题提供理论依据。
方法 采用多阶段整群抽样方法,选取贵州省2个县(区)内12个村60岁及以上老年人为研究对象,于2019年进行基线(T1)调查,2022年进行随访(T2),将同时完成两次调查且变量值完整的792例老年人纳入本次分析;采用交叉滞后模型分析认知功能与日常生活能力之间的纵向关系。
结果 在校正相应协变量后的交叉滞后分析结果显示,控制T1认知功能后,T1日常生活能力可以预测T2认知功能(β= -0.120, P<0.001);控制T1日常生活能力后,T1认知功能可以预测T2日常生活能力(β= -0.099, P=0.005)。进一步将ADL分为基础性日常生活能力(Basic Activities of Daily Living,BADL)和工具性日常生活能力(Instrumental Activities of Daily Living,IADL)后进行分析,在控制T1认知功能后,T1 IADL能够预测T2认知功能(β= -0.138, P<0.001),同样,控制T1 IADL后,T1认知功能可以预测T2 IADL(β= -0.124, P<0.001),BADL与认知功能之间没有预测作用。
结论 贵州农村老年人的认知功能与日常生活能力(仅IADL)之间存在纵向双向关联,提示了加强监测与干预老年人的认知功能有助于减少老年人的工具性日常生活能力下降风险,加强对工具性日常生活能力的训练对延缓认知下降也具有重要作用。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=PrGDW1kwlKvHoBnZg15wqA==, magXml=x40q6ggVy7aPA8+SEoROvg==, pdfUrl=null, pdf=BzxMJ4q+WiP9MMyXtER4+g==, pdfFileSize=830148, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=Xd1G3kKAVx67kGUmpC+ytg==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=pUNoqUWRuTfZlBKN45HLiQ==, mapNumber=null, authorCompany=null, fund=null, authors=
王静(1998—),女,硕士在读,研究方向:慢性病流行病学
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1.贵州医科大学公共卫生与健康学院,环境污染与疾病监控教育部重点实验室,贵州 贵阳 550025)])]), Author(id=1241826542679031858, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241826542867775556, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, authorId=1241826542679031858, language=EN, stringName=Shi-qi GUI, firstName=Shi-qi, middleName=null, lastName=GUI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1.贵州医科大学公共卫生与健康学院,环境污染与疾病监控教育部重点实验室,贵州 贵阳 550025)])]), Author(id=1241826543178154071, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241826543320760418, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, authorId=1241826543178154071, language=EN, stringName=Qiu-shuo LI, firstName=Qiu-shuo, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1.贵州医科大学公共卫生与健康学院,环境污染与疾病监控教育部重点实验室,贵州 贵阳 550025)])])], keywords=[Keyword(id=1241826545019453636, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=EN, orderNo=1, keyword=Cognitive function), Keyword(id=1241826545149477070, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=EN, orderNo=2, keyword=Activities of daily living), Keyword(id=1241826546697175256, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=EN, orderNo=3, keyword=Cross-lagged analysis), Keyword(id=1241826546827198681, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=CN, orderNo=1, keyword=认知功能), Keyword(id=1241826546948833504, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=CN, orderNo=2, keyword=日常生活能力), Keyword(id=1241826547062079719, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=CN, orderNo=3, keyword=交叉滞后模型)], refs=[Reference(id=1241826548471365911, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, doi=null, pmid=null, pmcid=null, year=2022, volume=12, issue=1, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=Duan J, Sam NB, Wang SJ, journalName=Scientific Reports, refType=null, unstructuredReference=
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1.贵州医科大学公共卫生与健康学院,环境污染与疾病监控教育部重点实验室,贵州 贵阳 550025)]), AuthorCompany(id=1241826540623823869, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, xref=2., ext=[AuthorCompanyExt(id=1241826540632212478, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, companyId=1241826540623823869, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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3.黔南民族医学高等专科学校)])], figs=[ArticleFig(id=1241826547355681009, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=EN, label=Fig.1, caption=
Cross-lagged panel analysis of cognitive function and activities of daily living (No control covariates), figureFileSmall=9PFEBWCtAXjX4OaoClgb0g==, figureFileBig=dyOsdzo443ngGs58CGYoDg==, tableContent=null), ArticleFig(id=1241826547460538611, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=CN, label=图1, caption=
认知功能与日常生活能力的交叉滞后分析(未调整协变量)注:路径系数为控制协变量后的标准化系数; *P<0.05,**P<0.01,***P<0.001;实线表示显著路径,虚线表示不显著的路径;A认知功能与ADL的交叉滞后模型结果;B认知功能与BADL的交叉滞后模型结果;C认知功能与IADL的交叉滞后模型结果。
, figureFileSmall=9PFEBWCtAXjX4OaoClgb0g==, figureFileBig=dyOsdzo443ngGs58CGYoDg==, tableContent=null), ArticleFig(id=1241826547607339257, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=EN, label=Fig.2, caption=
Cross-lagged panel analysis of cognitive function and activities of daily living (Controlled covariates), figureFileSmall=YS0jqIIRcPwcyV7toNEBgQ==, figureFileBig=EtyR1bmqLO8GZDgpKVM5yA==, tableContent=null), ArticleFig(id=1241826547712196861, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=CN, label=图2, caption=
认知功能与日常生活能力的交叉滞后分析(调整协变量后)注:路径系数为控制协变量后的标准化系数; *P<0.05,**P<0.01,***P<0.001;实线表示显著路径,虚线表示不显著的路径;控制的协变量包括:年龄、性别、婚姻状况、教育程度、家庭年收入、自评健康状况和体育锻炼情况。A认知功能与ADL的交叉滞后模型结果;B认知功能与BADL的交叉滞后模型结果;C认知功能与IADL的交叉滞后模型结果。
, figureFileSmall=YS0jqIIRcPwcyV7toNEBgQ==, figureFileBig=EtyR1bmqLO8GZDgpKVM5yA==, tableContent=null), ArticleFig(id=1241826547884163329, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=EN, label=Table 1, caption=
Basic characteristics of research objects (n=792)
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| 变量 | 基线(T1) | 随访(T2) | Z | P |
|---|
| 年龄[M(P25, P75)] | 70(66,75) | 73(69.77) | -9.562 | >0.001 |
| 女性[n(%)] | 474(59.8) | - | - | - |
| 在婚[n(%)] | 496(62.6) | 473(59.7) | -1.185 | 0.236 |
| 教育程度[n(%)] | | | - | - |
| 文盲/半文盲 | 600(75.8) | - | | |
| 小学 | 117(14.8) | - | | |
| 初中及以上 | 75(9.4) | - | | |
| 家庭年收入[n(%)] | | | -4.367 | <0.001 |
| <1万元 | 252(31.8) | 267(33.7) | | |
| 1~3万元 | 247(31.2) | 344(43.4) | | |
| 3~5万元 | 178(22.5) | 136(17.2) | | |
| >5万元 | 115(14.5) | 45(5.7) | | |
| 自评健康[n(%)] | | | -0.029 | 0.977 |
| 好 | 270(34.1) | 285(36.0) | | |
| 一般 | 229(28.9) | 298(37.6) | | |
| 差 | 293(37.0) | 209(26.4) | | |
| 锻炼[n(%)] | | | -5.395 | <0.001 |
| <10分钟 | 417(52.7) | 287(36.2) | | |
| 10~30分钟 | 151(19.1) | 247(31.2) | | |
| 31~60分钟 | 131(16.5) | 124(15.7) | | |
| >60分钟 | 93(11.7) | 134(16.9) | | |
| ADL[M(P25, P75)] | 15(14,17) | 14(14,16) | -7.738 | <0.001 |
| BADL[M(P25, P75)] | 6(6,6) | 6(6,6) | -0.577 | 0.564 |
| IADL[M(P25, P75)] | 9(8,11) | 8(8,10) | -7.753 | <0.001 |
| MMSE[M(P25, P75)] | 22(18,26) | 21(16,25) | -5.325 | <0.001 |
| 认知障碍[n(%)] | 194(24.5) | 286(36.1) | -5.028 | <0.001 |
), ArticleFig(id=1241826547993215238, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241675635962212607, language=CN, label=表1, caption=
研究对象的基本情况(n=792)
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 基线(T1) | 随访(T2) | Z | P |
|---|
| 年龄[M(P25, P75)] | 70(66,75) | 73(69.77) | -9.562 | >0.001 |
| 女性[n(%)] | 474(59.8) | - | - | - |
| 在婚[n(%)] | 496(62.6) | 473(59.7) | -1.185 | 0.236 |
| 教育程度[n(%)] | | | - | - |
| 文盲/半文盲 | 600(75.8) | - | | |
| 小学 | 117(14.8) | - | | |
| 初中及以上 | 75(9.4) | - | | |
| 家庭年收入[n(%)] | | | -4.367 | <0.001 |
| <1万元 | 252(31.8) | 267(33.7) | | |
| 1~3万元 | 247(31.2) | 344(43.4) | | |
| 3~5万元 | 178(22.5) | 136(17.2) | | |
| >5万元 | 115(14.5) | 45(5.7) | | |
| 自评健康[n(%)] | | | -0.029 | 0.977 |
| 好 | 270(34.1) | 285(36.0) | | |
| 一般 | 229(28.9) | 298(37.6) | | |
| 差 | 293(37.0) | 209(26.4) | | |
| 锻炼[n(%)] | | | -5.395 | <0.001 |
| <10分钟 | 417(52.7) | 287(36.2) | | |
| 10~30分钟 | 151(19.1) | 247(31.2) | | |
| 31~60分钟 | 131(16.5) | 124(15.7) | | |
| >60分钟 | 93(11.7) | 134(16.9) | | |
| ADL[M(P25, P75)] | 15(14,17) | 14(14,16) | -7.738 | <0.001 |
| BADL[M(P25, P75)] | 6(6,6) | 6(6,6) | -0.577 | 0.564 |
| IADL[M(P25, P75)] | 9(8,11) | 8(8,10) | -7.753 | <0.001 |
| MMSE[M(P25, P75)] | 22(18,26) | 21(16,25) | -5.325 | <0.001 |
| 认知障碍[n(%)] | 194(24.5) | 286(36.1) | -5.028 | <0.001 |
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