Article(id=1241065990910439515, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241065978004557893, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202410209, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1729008000000, receivedDateStr=2024-10-16, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773822790124, onlineDateStr=2026-03-18, pubDate=1740412800000, pubDateStr=2025-02-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773822790124, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773822790124, creator=13701087609, updateTime=1773822790124, updator=13701087609, issue=Issue{id=1241065978004557893, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='4', pageStart='577', pageEnd='768', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773822787047, creator=13701087609, updateTime=1773823194927, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241067688831808347, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241065978004557893, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241067688831808348, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241065978004557893, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=583, endPage=589, ext={EN=ArticleExt(id=1241065991275343994, articleId=1241065990910439515, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Epidemiological characteristics of hepatitis C and incidence trend prediction based on the BSTS model, Nanchang, 2005-2023, columnId=1228016567443718970, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods Advances, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the epidemiological characteristics of hepatitis C in Nanchang from 2005 to 2023 and evaluate the application value of the Bayesian structural time series (BSTS) model in predicting hepatitis C incidence trends, providing a scientific basis for the prevention and control of hepatitis C in the city.
Methods Data on hepatitis C incidence in Nanchang from January 2005 to December 2023 were collected. The trend and seasonal components of the monthly incidence data were analyzed using time series decomposition. The BSTS model was constructed using R software, with data from January 2005 to December 2022 used as the training set to fit the model, and data from January to December 2023 used as the test set to evaluate the model's predictive performance. The prediction accuracy of the BSTS model was compared with that of the autoregressive integrated moving average (ARIMA) model using mean absolute error (MAE), mean absolute percentage error (MAPE), root mean square error (RMSE), and root mean square percentage error (RMSPE) as evaluation metrics.
Results The overall incidence of hepatitis C in Nanchang has been on an upward trend, though the rate of increase has slowed since 2017. The data reveals significant cyclical and seasonal fluctuations, with a peak incidence in the spring months from March to May and a trough from January to February.The prediction performance indicators of the BSTS model (MAE=9.67, MAPE=17.61%, RMSE=11.99 and RMSPE=17.84) were all lower than those of the ARIMA model (MAE=12.12, MAPE=29.03%, RMSE=15.30, RMSPE=33.62). Based on the BSTS model, the total predicted number of hepatitis C cases in Nanchang from January 2024 to December 2024 is 308 (95% CI: 68-583), with an average monthly incidence of 26 cases (95% CI: 6-48).
Conclusion Hepatitis C incidence in Nanchang exhibits periodic and seasonal fluctuations. The BSTS model outperforms the ARIMA model in prediction performance and can provide technical support for the precise prevention and control of hepatitis C.
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目的 分析2005—2023年南昌市丙型肝炎流行特征,并探讨贝叶斯结构时间序列(BSTS)模型预测丙肝发病趋势的应用价值,为该市丙肝防控提供科学依据。
方法 收集2005年1月至2023年12月南昌市丙肝发病数据,采用时间序列分解法解析月发病数据的趋势和季节组分。运用R软件构建BSTS模型,其中2005年1月至2022年12月的数据作为训练集拟合BSTS模型,2023年1—12月数据作为测试集评估模型的预测效果,并将其预测准确性与自回归整合移动平均(ARIMA)模型进行比较,采用平均绝对误差(MAE)、平均绝对百分比误差(MAPE)、均方根误差(RMSE)和均方根百分比误差(RMSPE)评估预测准确性。
结果 南昌市丙肝发病总体呈上升趋势,2017年后发病数的增加有所减缓。发病数显示出明显的周期性和季节性变化,发病高发于春季3—5月,1—2月为低谷。BSTS模型预测性能指标MAE=9.67、MAPE=17.61%、RMSE=11.99和RMSPE=17.84均小于ARIMA模型预测性能指标MAE=12.12、MAPE=29.03%、RMSE=15.30、RMSPE=33.62。基于BSTS模型预测的2024年1月至2024年12月南昌市丙肝发病总数为308(95% CI:68~583)例,月均发病数为26(95% CI:6~48)例。
结论 南昌市丙肝发病存在周期性和季节性波动;BSTS模型预测性能更优,BSTS模型可为丙肝精准防控提供技术支撑。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=FfdjEFUxyMFCaqMh5qczZA==, magXml=wYkDwAnWv1WNUoxbozv58A==, pdfUrl=null, pdf=RZgukWzU1TujTlzihH2BKQ==, pdfFileSize=962836, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=uIG7J2+JC8Q3+ZK+OWB69g==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=SF9ALyyCDK8+A4cxshc1KA==, mapNumber=null, authorCompany=null, fund=null, authors=
莫佳丽(2001—),女,硕士在读,研究方向:流行病与卫生统计学
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Annals of Data Science,
2022,
9(5): 1025-1047., articleTitle=Forecasting the trends of covid-19 and causal impact of vaccines using Bayesian structural time series and ARIMA, refAbstract=null)], funds=[Fund(id=1241066001421365844, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, awardId=82160645; 82360667, language=CN, fundingSource=国家自然科学基金(82160645; 82360667), fundOrder=null, country=null), Fund(id=1241066001522029144, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, awardId=20212BAB206091, language=CN, fundingSource=江西省自然科学基金(20212BAB206091), fundOrder=null, country=null), Fund(id=1241066001631081050, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, awardId=202410613, language=CN, fundingSource=江西省卫生健康委科技计划(202410613), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1241065992651075824, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, xref=1., ext=[AuthorCompanyExt(id=1241065992655270132, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, companyId=1241065992651075824, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Epidemiology, School of Public Health, Nanchang University, Nanchang, Jiangxi 330006, China), AuthorCompanyExt(id=1241065992663658740, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, companyId=1241065992651075824, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.南昌大学公共卫生学院流行病学教研室,江西 南昌 330006)]), AuthorCompany(id=1241065992764322040, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, xref=2., ext=[AuthorCompanyExt(id=1241065992776904953, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, companyId=1241065992764322040, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.疾病预防与公共卫生江西省重点实验室)]), AuthorCompany(id=1241065992894345473, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, xref=3., ext=[AuthorCompanyExt(id=1241065992902734082, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, companyId=1241065992894345473, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.南昌市疾病预防控制中心)]), AuthorCompany(id=1241065993041146126, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, xref=4., ext=[AuthorCompanyExt(id=1241065993045340432, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, companyId=1241065993041146126, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
4.南昌市青云谱区疾病预防控制中心)])], figs=[ArticleFig(id=1241065998044951030, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Fig.1, caption=
Annual incidence and morbidity of hepatitis C in Nanchang from 2005 to 2023, figureFileSmall=K+k20iuJIikc9r0hHpJc6w==, figureFileBig=uIG7J2+JC8Q3+ZK+OWB69g==, tableContent=null), ArticleFig(id=1241065999550706170, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=图1, caption=
南昌市2005—2023年丙肝年发病数和发病率, figureFileSmall=K+k20iuJIikc9r0hHpJc6w==, figureFileBig=uIG7J2+JC8Q3+ZK+OWB69g==, tableContent=null), ArticleFig(id=1241065999886250510, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Fig.2, caption=
Time series of monthly incidence of hepatitis C in Nanchang from January 2005 to December 2023, figureFileSmall=xYYIgTAaJUF6yii9rhOgPA==, figureFileBig=dsTZV1u7hQ2DqHOL8l5eIA==, tableContent=null), ArticleFig(id=1241065999965942292, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=图2, caption=
南昌市2005年1月至2023年12月丙肝逐月发病数时序图, figureFileSmall=xYYIgTAaJUF6yii9rhOgPA==, figureFileBig=dsTZV1u7hQ2DqHOL8l5eIA==, tableContent=null), ArticleFig(id=1241066000079188505, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Fig.3, caption=
ACF and PACF plots of seasonally differenced hepatitis C incidence series, figureFileSmall=LyvF/XjSN2+Dx8aDNGxOaQ==, figureFileBig=BbI6Tayyh5xlHtarQD89/A==, tableContent=null), ArticleFig(id=1241066000209211937, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=图3, caption=
丙肝发病序列季节差分的自相关和偏自相关函数, figureFileSmall=LyvF/XjSN2+Dx8aDNGxOaQ==, figureFileBig=BbI6Tayyh5xlHtarQD89/A==, tableContent=null), ArticleFig(id=1241066000305680934, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Fig.4, caption=
Autocorrelation and Partial Autocorrelation Plots of Residual Series for ARIMA (A) and BSTS (B) Models, figureFileSmall=bNAr8vh/WhFoaQoGoxqvUA==, figureFileBig=6JYX7Lw4Ej0TyhGDB2lkjw==, tableContent=null), ArticleFig(id=1241066000402149932, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=图4, caption=
ARIMA (A)和BSTS(B)模型残差序列的ACF和PACF图, figureFileSmall=bNAr8vh/WhFoaQoGoxqvUA==, figureFileBig=6JYX7Lw4Ej0TyhGDB2lkjw==, tableContent=null), ArticleFig(id=1241066000498618926, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Table 1, caption=
Ljung-Box Q test for the residuals from ARIMA and BSTS models
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滞后期 (月) | ARIMA模型 | BSTS模型 |
|---|
| χ2值 | P值 | χ2值 | P值 |
|---|
| 1 | 0.017 | 0.895 | 0.277 | 0.599 |
| 2 | 0.375 | 0.829 | 0.809 | 0.667 |
| 3 | 0.421 | 0.936 | 4.283 | 0.232 |
| 4 | 0.636 | 0.959 | 7.284 | 0.122 |
| 5 | 0.775 | 0.979 | 7.887 | 0.163 |
| 6 | 0.776 | 0.993 | 8.585 | 0.198 |
| 7 | 0.966 | 0.995 | 10.351 | 0.170 |
| 8 | 4.020 | 0.855 | 14.699 | 0.065 |
| 9 | 4.521 | 0.874 | 14.939 | 0.093 |
| 10 | 4.603 | 0.917 | 15.110 | 0.128 |
), ArticleFig(id=1241066000632836660, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=表1, caption=
ARIMA和BSTS模型残差的Ljung-Box Q检验
, figureFileSmall=null, figureFileBig=null, tableContent=
滞后期 (月) | ARIMA模型 | BSTS模型 |
|---|
| χ2值 | P值 | χ2值 | P值 |
|---|
| 1 | 0.017 | 0.895 | 0.277 | 0.599 |
| 2 | 0.375 | 0.829 | 0.809 | 0.667 |
| 3 | 0.421 | 0.936 | 4.283 | 0.232 |
| 4 | 0.636 | 0.959 | 7.284 | 0.122 |
| 5 | 0.775 | 0.979 | 7.887 | 0.163 |
| 6 | 0.776 | 0.993 | 8.585 | 0.198 |
| 7 | 0.966 | 0.995 | 10.351 | 0.170 |
| 8 | 4.020 | 0.855 | 14.699 | 0.065 |
| 9 | 4.521 | 0.874 | 14.939 | 0.093 |
| 10 | 4.603 | 0.917 | 15.110 | 0.128 |
), ArticleFig(id=1241066000783831609, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Table 2, caption=
Predicted hepatitis C cases in Nanchang from January to December 2023 using ARIMA (1, 1, 1) (0, 1, 1)12 and BSTS models
, figureFileSmall=null, figureFileBig=null, tableContent=
| 月份 | 实际发病数(例) | ARIMA模型预测发病数 (95% CI)(例) | BTST模型预测发病数 (95% CI)(例) |
|---|
| 1 | 20 | 18(0~36) | 18(0~35) |
| 2 | 41 | 16(3~35) | 19(0~37) |
| 3 | 56 | 34(14~53) | 35(14~56) |
| 4 | 55 | 5(13~45) | 29(10~49) |
| 5 | 46 | 26(6~46) | 28(9~51) |
| 6 | 44 | 32(11~52) | 29(8~51) |
| 7 | 34 | 29(8~49) | 26(5~50) |
| 8 | 43 | 34(14~55) | 28(2~53) |
| 9 | 34 | 32(11~53) | 26(7~51) |
| 10 | 29 | 25(4~47) | 22(4~47) |
| 11 | 24 | 32(10~53) | 25(3~53) |
| 12 | 24 | 30(8~51) | 23(6~50) |
), ArticleFig(id=1241066000897077821, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=表2, caption=
ARIMA(1,1,1)(0,1,1)12和BSTS模型预测的2023年1月至12月南昌市丙肝发数
, figureFileSmall=null, figureFileBig=null, tableContent=
| 月份 | 实际发病数(例) | ARIMA模型预测发病数 (95% CI)(例) | BTST模型预测发病数 (95% CI)(例) |
|---|
| 1 | 20 | 18(0~36) | 18(0~35) |
| 2 | 41 | 16(3~35) | 19(0~37) |
| 3 | 56 | 34(14~53) | 35(14~56) |
| 4 | 55 | 5(13~45) | 29(10~49) |
| 5 | 46 | 26(6~46) | 28(9~51) |
| 6 | 44 | 32(11~52) | 29(8~51) |
| 7 | 34 | 29(8~49) | 26(5~50) |
| 8 | 43 | 34(14~55) | 28(2~53) |
| 9 | 34 | 32(11~53) | 26(7~51) |
| 10 | 29 | 25(4~47) | 22(4~47) |
| 11 | 24 | 32(10~53) | 25(3~53) |
| 12 | 24 | 30(8~51) | 23(6~50) |
), ArticleFig(id=1241066001010324033, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Table 3, caption=
Comparison of Forecasting Performance between ARIMA(1,1,1)(0,1,1)12 and BSTS Models
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | ARIMA模型 | BSTS模型 | MDM | P值 |
|---|
| MAE | 12.12 | 9.67 | 2.164 | <0.001 |
| MAPE% | 29.03 | 17.61 | 3.572 | <0.001 |
| RMSE | 15.30 | 11.99 | 3.187 | <0.001 |
| RMSPE | 33.62 | 17.84 | 3.915 | <0.001 |
), ArticleFig(id=1241066001123570247, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=表3, caption=
ARIMA(1,1,1)(0,1,1)12和BSTS模型的预测性能比较
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | ARIMA模型 | BSTS模型 | MDM | P值 |
|---|
| MAE | 12.12 | 9.67 | 2.164 | <0.001 |
| MAPE% | 29.03 | 17.61 | 3.572 | <0.001 |
| RMSE | 15.30 | 11.99 | 3.187 | <0.001 |
| RMSPE | 33.62 | 17.84 | 3.915 | <0.001 |
), ArticleFig(id=1241066001190679116, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=EN, label=Table 4, caption=
Predicted hepatitis C cases in Nanchang from January 2023 to December 2024 based on BSTS model
, figureFileSmall=null, figureFileBig=null, tableContent=
| 时间(年.月) | 预测发病数(95% CI)(例) |
|---|
| 2024.01 | 19(1~38) |
| 2024.02 | 23(3~45) |
| 2024.03 | 39(19~59) |
| 2024.04 | 32(10~54) |
| 2024.05 | 31(9~53) |
| 2024.06 | 33(9~54) |
| 2024.07 | 28(4~52) |
| 2024.08 | 32(5~58) |
| 2024.09 | 29(3~55) |
| 2024.10 | 25(4~51) |
| 2024.11 | 28(0~55) |
| 2024.12 | 25(5~55) |
), ArticleFig(id=1241066001274565200, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241065990910439515, language=CN, label=表4, caption=
基于BSTS模型预测的南昌市2024年1月至2024年12月丙肝发病数
, figureFileSmall=null, figureFileBig=null, tableContent=
| 时间(年.月) | 预测发病数(95% CI)(例) |
|---|
| 2024.01 | 19(1~38) |
| 2024.02 | 23(3~45) |
| 2024.03 | 39(19~59) |
| 2024.04 | 32(10~54) |
| 2024.05 | 31(9~53) |
| 2024.06 | 33(9~54) |
| 2024.07 | 28(4~52) |
| 2024.08 | 32(5~58) |
| 2024.09 | 29(3~55) |
| 2024.10 | 25(4~51) |
| 2024.11 | 28(0~55) |
| 2024.12 | 25(5~55) |
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