Article(id=1241035821252408181, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241035810628235909, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202407069, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1720195200000, receivedDateStr=2024-07-06, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773815597117, onlineDateStr=2026-03-18, pubDate=1733760000000, pubDateStr=2024-12-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773815597117, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773815597117, creator=13701087609, updateTime=1773815597117, updator=13701087609, issue=Issue{id=1241035810628235909, tenantId=1146029695717560320, journalId=1227665162245664772, year='2024', volume='51', issue='23', pageStart='4225', pageEnd='4416', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773815594584, creator=13701087609, updateTime=1773815743629, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241036435843764756, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241035810628235909, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241036435843764757, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241035810628235909, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=4255, endPage=4259, ext={EN=ArticleExt(id=1241035821806056338, articleId=1241035821252408181, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Analysis of the trend of appendicitis disease burden among individuals aged 70 and above in China from 1990 to 2019, columnId=1240413921954295836, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze relevant data on the burden of appendicitis among individuals aged 70 and above in China from 1990 to 2019, describe its current status and epidemiological trends, and provide scientific evidence for exploring prevention and treatment strategies for appendicitis in the elderly population in China.
Methods Utilizing the 2019 Global Burden of Disease data, this study analyzed the incidence, mortality, and disability-adjusted life years (DALY) of appendicitis in individuals aged 70 and above in China from 1990 to 2019. The Join point regression model was used to calculate the average annual percentage change (AAPC).
Results From 1990 to 2019, the incidence of appendicitis among individuals aged 70 and above in China exhibited a year-on-year increasing trend, with the most significant rise occurring between 2000 and 2005. In contrast, both the mortality rate and DALY rate showed a declining trend during the same period, with a substantial decrease starting in 2004. However, the decline rate has slowed down since 2008. Among different gender and age group compositions, the highest incidence was observed in the 70-74 age group, with a higher incidence in females compared to males. Conversely, the highest mortality and DALY rates were found in the 85-89 age group, with both rates being higher in males than in females.
Conclusion Since 1990, the burden of mortality and DALY due to appendicitis among individuals aged 70 and above in China has gradually decreased, yet the incidence remains at a relatively high level. Therefore, it is essential for China to adopt various prevention and treatment strategies for the elderly population to reduce the disease burden of appendicitis in those aged 70 and above.
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目的 分析1990—2019年中国≥70岁老年人阑尾炎疾病负担的相关数据,描述其现状及流行趋势,为探索中国老年人阑尾炎防治策略提供科学依据。
方法 利用2019年全球疾病负担数据,选取1990—2019年中国≥70岁老年人群阑尾炎的发病率、死亡率和伤残调整寿命年(disability~adjusted life years,DALY)进行分析,并采用joinpoint回归模型计算相应的平均年度变化百分比(average annual percentage change,AAPC)。
结果 1990—2019年,我国≥70岁老年人阑尾炎发病率呈逐年上升趋势,2000—2005年上升最为明显,同期死亡率和DALY率则呈下降趋势,2004年开始死亡率和DALY率出现大幅下降,但自2008年以后下降趋势有所减缓。在各指标性别和年龄组构成中,70~74岁年龄段的发病率最高,且女性发病率高于男性;而在85~89岁年龄段死亡率和DALY率最高,且男性的死亡率和DALY率均高于女性。
结论 自1990年以来,我国≥70岁老年人阑尾炎死亡及DALY负担逐渐减轻,但发病率仍处于较高水平,因此,未来中国对老年人群体应采取多种方式防治,以降低≥70岁老年人阑尾炎的疾病负担。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=4ywroVAQhGm8eN603xirpA==, magXml=9kwu9b7rmPi0cspvtA02JQ==, pdfUrl=null, pdf=kOdjPxxfz80HrHZgTwHFvg==, pdfFileSize=829859, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=fqqAriGY+DGkYcN658WWbw==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=JRn5U4cHSO0DbCIIoHuiog==, mapNumber=null, authorCompany=null, fund=null, authors=
牛聚宝(1998—),男,硕士在读,研究方向:消化系统疾病临床及基础研究
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1.兰州大学第二临床医学院,甘肃 兰州 730000)]), AuthorCompany(id=1241069111988514882, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, xref=2., ext=[AuthorCompanyExt(id=1241069111992709188, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, companyId=1241069111988514882, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.兰州大学第二医院普通外科,甘肃 兰州 730000)])], figs=[ArticleFig(id=1241069115872440548, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=EN, label=Figure 1, caption=
Trends of incidence (A), mortality (B) and DALY rate(C) of appendicitis in the elderly aged 70 years and older in China by gender from 1990 to 2019, figureFileSmall=LAltQ/dmRGt0YFL76BdLQg==, figureFileBig=P+hz3PX60akz5qYtFDfBEg==, tableContent=null), ArticleFig(id=1241069115956326640, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=CN, label=图1, caption=
1990—2019年中国70岁及以上老年人阑尾炎不同性别发病率、死亡率和DALY率变化趋势注:图A为发病率;图B为死亡率;图C为DALY率;*表示P<0.05。
, figureFileSmall=LAltQ/dmRGt0YFL76BdLQg==, figureFileBig=P+hz3PX60akz5qYtFDfBEg==, tableContent=null), ArticleFig(id=1241069116073767164, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=EN, label=Figure 2, caption=
Appendicitis incidence, mortality, and DALY rates in the elderly by age and sex in China in 2019, figureFileSmall=2xBHU2vA4vHUwJ0ma7SBPw==, figureFileBig=0t7oezsVdCRz81lhUIZMkA==, tableContent=null), ArticleFig(id=1241069116170236167, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=CN, label=图2, caption=
2019年中国分年龄及性别老年人阑尾炎发病率、死亡率及DALY率的情况, figureFileSmall=2xBHU2vA4vHUwJ0ma7SBPw==, figureFileBig=0t7oezsVdCRz81lhUIZMkA==, tableContent=null), ArticleFig(id=1241069116304453904, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=EN, label=Table 1, caption=
Incidence, mortality and disease burden of appendicitis in the elderly aged 70 years and older in China in 1990 and 2019
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | 人群 | 人数 | 率(/10万) |
|---|
| 1990年 | 2019年 | 变化率(%) | 1990年 | 2019年 | 变化率(%) |
|---|
| 发病 | 男性 | 2 935 | 21 004 | 615.7 | 23.81 | 60.95 | 155.9 |
| 女性 | 4 547 | 27 501 | 504.9 | 27.57 | 65.13 | 136.2 |
| 总人群 | 7 481 | 48 505 | 548.4 | 19.55 | 44.93 | 129.8 |
| 死亡 | 男性 | 596 | 492 | -17.5 | 3.61 | 1.00 | -72.3 |
| 女性 | 878 | 524 | -40.3 | 4.03 | 0.89 | -77.9 |
| 总人群 | 1 473 | 1 015 | -31.1 | 3.85 | 0.94 | -75.6 |
| DALY | 男性 | 8 995.63 | 6 874.08 | -23.6 | 54.49 | 13.96 | -74.4 |
| 女性 | 12 336.42 | 6 696.61 | -45.7 | 56.72 | 11.40 | -79.9 |
| 总人群 | 21 332.05 | 13 570.69 | -36.4 | 55.76 | 12.57 | -77.5 |
), ArticleFig(id=1241069116396728599, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=CN, label=表1, caption=
1990和2019年中国70岁及以上老年人阑尾炎发病、死亡和疾病负担情况
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | 人群 | 人数 | 率(/10万) |
|---|
| 1990年 | 2019年 | 变化率(%) | 1990年 | 2019年 | 变化率(%) |
|---|
| 发病 | 男性 | 2 935 | 21 004 | 615.7 | 23.81 | 60.95 | 155.9 |
| 女性 | 4 547 | 27 501 | 504.9 | 27.57 | 65.13 | 136.2 |
| 总人群 | 7 481 | 48 505 | 548.4 | 19.55 | 44.93 | 129.8 |
| 死亡 | 男性 | 596 | 492 | -17.5 | 3.61 | 1.00 | -72.3 |
| 女性 | 878 | 524 | -40.3 | 4.03 | 0.89 | -77.9 |
| 总人群 | 1 473 | 1 015 | -31.1 | 3.85 | 0.94 | -75.6 |
| DALY | 男性 | 8 995.63 | 6 874.08 | -23.6 | 54.49 | 13.96 | -74.4 |
| 女性 | 12 336.42 | 6 696.61 | -45.7 | 56.72 | 11.40 | -79.9 |
| 总人群 | 21 332.05 | 13 570.69 | -36.4 | 55.76 | 12.57 | -77.5 |
), ArticleFig(id=1241069116572889382, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=EN, label=Table 2, caption=
Average annual percentage (AAPC) (%) and 95%CI of the disease burden of appendicitis in the elderly aged 70 years and older in China from 1990 to 2019
, figureFileSmall=null, figureFileBig=null, tableContent=
| 分组(岁) | 总体 | 男性 | 女性 |
|---|
| 发病率 | | | |
| ≥70 | 2.93 a (2.81~3.03) | 3.08 a (2.94~3.19) | 2.84 a (2.73~2.94) |
| 70~74 | 4.56 a (4.40~4.70) | 4.51 a (4.35~4.65) | 4.64 a (4.48~4.8) |
| 75~79 | 2.15 a (2.05~2.23) | 1.97 a (1.87~2.06) | 2.32 a (2.22~2.42) |
| 80~84 | 0.90 a (0.83~0.96) | 1.11 a (1.04~1.17) | 0.75 a (0.67~0.82) |
| 85~89 | -0.09 a (-0.14~-0.06) | 0.60 a (0.56~0.62) | -0.50 a (-0.56~-0.46) |
| 90~94 | -1.22 a(-1.25~-1.19) | 0.23 a (0.20~0.26) | -1.59 a (-1.62~-1.57) |
| ≥95 | -2.13 a(-2.17~-2.11) | -0.25 a (-0.27~0.23) | -2.37 a (-2.41~-2.34) |
| 死亡率 | | | |
| ≥70 | -4.84 a (-4.92~-4.74) | -4.38 a (-4.46~-4.29) | -5.14 a (-5.23~-5.04) |
| 70~74 | -5.92 a (-6.01~-5.81) | -5.49 a (-5.55~-5.43) | -6.42 a (-6.53~-6.40) |
| 75~79 | -5.46 a (-5.56~-5.35) | -4.91 a (-5.01~-4.81) | -6.06 a (-6.23~-5.89) |
| 80~84 | -5.01 a (-5.12~-4.89) | -4.51 a (-4.62~-4.38) | -5.37 a (-5.47~-5.25) |
| 85~89 | -4.60 a (-4.67~-4.53) | -3.86 a (-3.97~-3.77) | -5.05 a (-5.15~-4.97) |
| 90~94 | -4.45 a (-4.53~-4.38) | -3.43 a (-3.57~-3.30) | -4.68 a (-4.82~-4.59) |
| ≥95 | -3.56 a (-3.65~-3.48) | -2.74 a (-2.82~-2.66) | -3.63 a (-3.73~-3.51) |
| DALY率 | | | |
| ≥70 | -5.10 a (-5.19~-5.00) | -4.62 a (-4.70~-4.54) | -5.44 a (-5.55~-5.33) |
| 70~74 | -5.63 a (-5.72~-5.51) | -5.29 a (-5.38~-5.19) | -6.02 a (-6.13~-5.90) |
| 75~79 | -5.38 a (-5.48~-5.27) | -4.86 a (-4.96~-4.75) | -5.96 a (-6.13~-5.78) |
| 80~84 | -4.97 a (-5.08~-4.86) | -4.48 a (-4.59~-4.37) | -5.32 a (-5.43~-5.19) |
| 85~89 | -4.58 a (-4.66~-4.52) | -3.84 a (-3.99~-3.72) | -5.03 a (-5.14~-4.94) |
| 90~94 | -4.46 a (-4.53~-4.39) | -3.42 a (-3.56~-3.29) | -4.70 a (-4.82~-4.61) |
| ≥95 | -3.66 a (-3.73~-3.58) | -2.80 a (-2.88~-2.72) | -3.73 a (-3.83~-3.61) |
), ArticleFig(id=1241069116832936247, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241035821252408181, language=CN, label=表2, caption=
1990—2019年中国70岁及以上老年人阑尾炎疾病负担[AAPC(%),95%CI]
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| 分组(岁) | 总体 | 男性 | 女性 |
|---|
| 发病率 | | | |
| ≥70 | 2.93 a (2.81~3.03) | 3.08 a (2.94~3.19) | 2.84 a (2.73~2.94) |
| 70~74 | 4.56 a (4.40~4.70) | 4.51 a (4.35~4.65) | 4.64 a (4.48~4.8) |
| 75~79 | 2.15 a (2.05~2.23) | 1.97 a (1.87~2.06) | 2.32 a (2.22~2.42) |
| 80~84 | 0.90 a (0.83~0.96) | 1.11 a (1.04~1.17) | 0.75 a (0.67~0.82) |
| 85~89 | -0.09 a (-0.14~-0.06) | 0.60 a (0.56~0.62) | -0.50 a (-0.56~-0.46) |
| 90~94 | -1.22 a(-1.25~-1.19) | 0.23 a (0.20~0.26) | -1.59 a (-1.62~-1.57) |
| ≥95 | -2.13 a(-2.17~-2.11) | -0.25 a (-0.27~0.23) | -2.37 a (-2.41~-2.34) |
| 死亡率 | | | |
| ≥70 | -4.84 a (-4.92~-4.74) | -4.38 a (-4.46~-4.29) | -5.14 a (-5.23~-5.04) |
| 70~74 | -5.92 a (-6.01~-5.81) | -5.49 a (-5.55~-5.43) | -6.42 a (-6.53~-6.40) |
| 75~79 | -5.46 a (-5.56~-5.35) | -4.91 a (-5.01~-4.81) | -6.06 a (-6.23~-5.89) |
| 80~84 | -5.01 a (-5.12~-4.89) | -4.51 a (-4.62~-4.38) | -5.37 a (-5.47~-5.25) |
| 85~89 | -4.60 a (-4.67~-4.53) | -3.86 a (-3.97~-3.77) | -5.05 a (-5.15~-4.97) |
| 90~94 | -4.45 a (-4.53~-4.38) | -3.43 a (-3.57~-3.30) | -4.68 a (-4.82~-4.59) |
| ≥95 | -3.56 a (-3.65~-3.48) | -2.74 a (-2.82~-2.66) | -3.63 a (-3.73~-3.51) |
| DALY率 | | | |
| ≥70 | -5.10 a (-5.19~-5.00) | -4.62 a (-4.70~-4.54) | -5.44 a (-5.55~-5.33) |
| 70~74 | -5.63 a (-5.72~-5.51) | -5.29 a (-5.38~-5.19) | -6.02 a (-6.13~-5.90) |
| 75~79 | -5.38 a (-5.48~-5.27) | -4.86 a (-4.96~-4.75) | -5.96 a (-6.13~-5.78) |
| 80~84 | -4.97 a (-5.08~-4.86) | -4.48 a (-4.59~-4.37) | -5.32 a (-5.43~-5.19) |
| 85~89 | -4.58 a (-4.66~-4.52) | -3.84 a (-3.99~-3.72) | -5.03 a (-5.14~-4.94) |
| 90~94 | -4.46 a (-4.53~-4.39) | -3.42 a (-3.56~-3.29) | -4.70 a (-4.82~-4.61) |
| ≥95 | -3.66 a (-3.73~-3.58) | -2.80 a (-2.88~-2.72) | -3.73 a (-3.83~-3.61) |
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