Article(id=1241034442781815084, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241034441380917539, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202502127, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1739116800000, receivedDateStr=2025-02-10, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773815268464, onlineDateStr=2026-03-18, pubDate=1749484800000, pubDateStr=2025-06-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773815268464, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773815268464, creator=13701087609, updateTime=1773815268464, updator=13701087609, issue=Issue{id=1241034441380917539, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='11', pageStart='1921', pageEnd='2112', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773815268130, creator=13701087609, updateTime=1773815340947, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241034746873049765, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241034441380917539, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241034746873049766, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241034441380917539, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=2096, endPage=2100, ext={EN=ArticleExt(id=1241034443041861938, articleId=1241034442781815084, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Assessment of the burden and risk classification of Vibrio parahaemolyticus foodborne diseases in Liaoning Province, columnId=1228016573156360233, journalTitle=Modern Preventive Medicine, columnName=Disease Control and Prevention, runingTitle=null, highlight=null, articleAbstract=
Objective To understand the burden of foodborne diseases caused by Vibrio parahaemolyticus in Liaoning Province and to clarify the risk associated with different types of food, thereby assisting in foodborne disease prevention efforts.
Methods Using surveillance data of foodborne disease cases from 2014 to 2023 in Liaoning Province, the population level of foodborne diseases burden caused by Vibrio parahaemolyticus was estimated using the disease burden pyramid model. The main food types contributing to Vibrio parahaemolyticus infections were also classified by attributable risk.
Results Based on active surveillance data from sentinel hospitals, the multiple factor for Vibrio parahaemolyticus infections was found to be 86.50,indicating that for every reported case, approximately 87 cases occurred within the coverage area of the sentinel monitoring hospitals. Utilizing provincial case data, the multiple factor was 428.37 (95% CI: 424.05-432.62), suggesting that for each reported case, around 428 cases occurred across the province. It was estimated that from 2014 to 2023, there were a total of 440 448 (95% CI: 421 202-460 607) cases of Vibrio parahaemolyticus infections in Liaoning Province, with an annual incidence rate of approximately 103.41 per 100 000 people (95% CI: 98.85-108.11). Risk classification for various food items indicated that seafood posed the highest risk, accounting for 50.20% of infections, with shellfish being the highest-risk food type, followed by shrimp and watermelon.
Conclusion Based on the multiple factor; it can be concluded that the burden of Vibrio parahaemolyticus infections in Liaoning Province is slightly higher than in other coastal regions. Seafood, particularly shellfish, is the primary cause of foodborne diseases associated with Vibrio parahaemolyticus in Liaoning Province. Continued enhancement of prevention and education efforts targeting key populations and regions is necessary to guide residents in the proper consumption of seafood, as well as to improve disease burden assessment work.
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目的 了解辽宁省副溶血性弧菌导致的食源性疾病负担状况,明确不同食物种类对感染造成的风险情况,为食源性疾病预防工作提供帮助。
方法 利用2014—2023年辽宁省食源性疾病病例监测数据,使用疾病负担金字塔模型估计副溶血性弧菌导致食源性疾病的人群负担水平,并对造成副溶血性弧菌感染的主要食品种类进行归因风险分级。
结果 基于哨点医院主动监测数据构建金字塔模型,副溶血性弧菌感染低估系数为86.50,即监测到1例副溶血性弧菌感染病例,哨点监测医院覆盖范围内共发生约87例病例;基于全省病例数据构建金字塔模型,副溶血性弧菌感染低估系数428.37(95%CI:424.05~432.62),即每监测到1例副溶血性弧菌感染病例,全省范围内共发生约428例病例。估计2014—2023年辽宁省全省共发生副溶血性弧菌感染440 448例(95%CI:421 202~460 607),年发病率约为103.41/10万(95%CI:98.85~108.11)。对导致副溶血性弧菌感染的各类食品进行风险分级,认为水产品造成的风险最高,50.20%的感染可归因于水产品,贝类是风险最高的食物种类,其次为虾类和西瓜。
结论 基于低估系数,可以认为辽宁省副溶血性弧菌感染负担水平略高于其他沿海地区,水产品,尤其是贝类,是导致辽宁省副溶血性弧菌食源性疾病的最主要原因,应继续加强对重点人群及地区的预防宣教工作,指导居民正确食用海产品,同时完善疾病负担评估工作。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=dm2A770scxveYOW3ffTsWA==, magXml=Em/RMQgLWfW1y7bKcYVF/A==, pdfUrl=null, pdf=tOhmmWUaUI9vBwVqiknOKQ==, pdfFileSize=926528, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=LrAq8vqx5NCpqnlcO2ja+Q==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=UYBRdKesIK+h5DN+k2/NUA==, mapNumber=null, authorCompany=null, fund=null, authors=
于浩淼(2000—),女,硕士在读,研究方向:食品卫生
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于浩淼(2000—),女,硕士在读,研究方向:食品卫生
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The risk levels of Vibrio parahaemolyticus infection caused by different food types, figureFileSmall=jrKr/iCimdyu30qIh9lTtA==, figureFileBig=ky6FdVvpsIQUeHn9qgg8vw==, tableContent=null), ArticleFig(id=1241050834457383233, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=CN, label=图3, caption=
不同食品种类造成副溶血性弧菌感染的风险程度, figureFileSmall=jrKr/iCimdyu30qIh9lTtA==, figureFileBig=ky6FdVvpsIQUeHn9qgg8vw==, tableContent=null), ArticleFig(id=1241050834633544009, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=EN, label=Figure 4, caption=
The risk levels of Vibrio parahaemolyticus infection caused by different foods, figureFileSmall=MS/GJfjRmgpxvHnosQgZTg==, figureFileBig=m8LJKh5X/6MABcvkOPEasQ==, tableContent=null), ArticleFig(id=1241050835325604178, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=CN, label=图4, caption=
具体食品造成副溶血性弧菌感染的风险程度, figureFileSmall=MS/GJfjRmgpxvHnosQgZTg==, figureFileBig=m8LJKh5X/6MABcvkOPEasQ==, tableContent=null), ArticleFig(id=1241050835921195356, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=EN, label=Table 1, caption=
Methods for probability estimation of the number of infection cases of Vibrio parahaemolyticus in the population
, figureFileSmall=null, figureFileBig=null, tableContent=
| 低估系数 | 概率估计(Beta分布) | 实际病例数 | 补充病例数(负二项分布) |
|---|
| 报告率p5 | Beta~(报告人数+1,阳性人数-报告人数+1) | S6 | Negbin~(S6,p5) |
| 敏感度p4 | p4
| S5=S6+Negbin~(S6,p5) | Negbin~(S5,p4) |
| 检测率p3 | Beta~(检测人数+1,采样人数-检测人数+1) | S4=S5+Negbin~(S5,p4) | Negbin~(S4,p3) |
| 采样率p2 | Beta~(采样人数+1,就诊人数-采样人数+1) | S3=S4+Negbin~(S4,p3) | Negbin~(S3,p5) |
| 就诊率p1 | Beta~(就诊人数+1,发病人数-就诊人数+1) | S2=S3+Negbin~(S3,p2) | Negbin~(S2,p1) |
| 实际感染 | — | S=S2+Negbin~(S2,p1) | — |
), ArticleFig(id=1241050836063801698, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=CN, label=表1, caption=
人群副溶感染实际病例数概率估计方法
, figureFileSmall=null, figureFileBig=null, tableContent=
| 低估系数 | 概率估计(Beta分布) | 实际病例数 | 补充病例数(负二项分布) |
|---|
| 报告率p5 | Beta~(报告人数+1,阳性人数-报告人数+1) | S6 | Negbin~(S6,p5) |
| 敏感度p4 | p4
| S5=S6+Negbin~(S6,p5) | Negbin~(S5,p4) |
| 检测率p3 | Beta~(检测人数+1,采样人数-检测人数+1) | S4=S5+Negbin~(S5,p4) | Negbin~(S4,p3) |
| 采样率p2 | Beta~(采样人数+1,就诊人数-采样人数+1) | S3=S4+Negbin~(S4,p3) | Negbin~(S3,p5) |
| 就诊率p1 | Beta~(就诊人数+1,发病人数-就诊人数+1) | S2=S3+Negbin~(S3,p2) | Negbin~(S2,p1) |
| 实际感染 | — | S=S2+Negbin~(S2,p1) | — |
), ArticleFig(id=1241050836181242220, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=EN, label=Table 2, caption=
The probability estimation of the infection probability of Vibrio parahaemolyticus in different age groups in Liaoning Province
, figureFileSmall=null, figureFileBig=null, tableContent=
年龄组 (岁) | 监测数据 | 概率估计(95%CI) |
|---|
| 病例数 | 年发病率 (/10万) | 病例数 | 年发病率(/10万) |
|---|
| <1 | 1 | 0.05 | 428(410~448) | 19.46(18.62~20.36) |
| 1~4 | 0 | 0.00 | 0 | 0.00 |
| 5~9 | 17 | 0.10 | 7 280(6 803~7 801) | 43.85(41.97~45.87) |
| 10~14 | 8 | 0.05 | 3 426(3 208~3 671) | 20.90(19.50~22.38) |
| 15~24 | 135 | 0.38 | 57 884(54 039~61 939) | 175.34(163.61~187.83) |
| 25~44 | 489 | 0.42 | 209 668(195 623~224 311) | 178.24(170.42~186.41) |
| 45~64 | 299 | 0.20 | 128 205(119 573~137 391) | 84.66(79.03~90.60) |
| ≥65 | 79 | 0.11 | 33 873(31 625~36 228) | 45.67(42.69~48.93) |
), ArticleFig(id=1241050836298682739, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=CN, label=表2, caption=
概率估计辽宁省不同年龄组副溶血性弧菌感染情况
, figureFileSmall=null, figureFileBig=null, tableContent=
年龄组 (岁) | 监测数据 | 概率估计(95%CI) |
|---|
| 病例数 | 年发病率 (/10万) | 病例数 | 年发病率(/10万) |
|---|
| <1 | 1 | 0.05 | 428(410~448) | 19.46(18.62~20.36) |
| 1~4 | 0 | 0.00 | 0 | 0.00 |
| 5~9 | 17 | 0.10 | 7 280(6 803~7 801) | 43.85(41.97~45.87) |
| 10~14 | 8 | 0.05 | 3 426(3 208~3 671) | 20.90(19.50~22.38) |
| 15~24 | 135 | 0.38 | 57 884(54 039~61 939) | 175.34(163.61~187.83) |
| 25~44 | 489 | 0.42 | 209 668(195 623~224 311) | 178.24(170.42~186.41) |
| 45~64 | 299 | 0.20 | 128 205(119 573~137 391) | 84.66(79.03~90.60) |
| ≥65 | 79 | 0.11 | 33 873(31 625~36 228) | 45.67(42.69~48.93) |
), ArticleFig(id=1241050836529369466, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=EN, label=Table 3, caption=
Burden ranking of food category-pathogen combinations by Vibrio parahaemolyticus in Liaoning Province from 2014 to 2023
, figureFileSmall=null, figureFileBig=null, tableContent=
| 食品种类 | YLDs* | 百分比(%) |
|---|
| 水产品 | 128.67 | 50.20 |
| 肉与肉制品 | 42.30 | 16.50 |
| 水果及其制品 | 23.81 | 9.29 |
| 蔬菜及其制品 | 15.96 | 6.23 |
| 米面制品 | 12.16 | 4.74 |
| 混合食品 | 11.40 | 4.45 |
| 多种食品 | 6.84 | 2.67 |
| 豆及豆制品 | 5.83 | 2.27 |
| 冷冻饮品 | 5.07 | 1.98 |
| 乳与乳制品 | 2.28 | 0.89 |
| 蛋与蛋制品 | 2.03 | 0.79 |
), ArticleFig(id=1241050836705530244, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=CN, label=表3, caption=
2014—2023年辽宁省副溶血性弧菌感染食品种类-病原体组合负担排序
, figureFileSmall=null, figureFileBig=null, tableContent=
| 食品种类 | YLDs* | 百分比(%) |
|---|
| 水产品 | 128.67 | 50.20 |
| 肉与肉制品 | 42.30 | 16.50 |
| 水果及其制品 | 23.81 | 9.29 |
| 蔬菜及其制品 | 15.96 | 6.23 |
| 米面制品 | 12.16 | 4.74 |
| 混合食品 | 11.40 | 4.45 |
| 多种食品 | 6.84 | 2.67 |
| 豆及豆制品 | 5.83 | 2.27 |
| 冷冻饮品 | 5.07 | 1.98 |
| 乳与乳制品 | 2.28 | 0.89 |
| 蛋与蛋制品 | 2.03 | 0.79 |
), ArticleFig(id=1241050836936216973, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=EN, label=Table 4, caption=
Ranking of specific food-pathogen combinations by Vibrio parahaemolyticus in Liaoning Province from 2014 to 2023
, figureFileSmall=null, figureFileBig=null, tableContent=
| 具体食品 | YLDs* | 百分比(%) |
|---|
| 贝类 | 35.97 | 14.03 |
| 虾 | 24.32 | 9.49 |
| 西瓜 | 15.70 | 6.13 |
| 螃蟹 | 13.68 | 5.34 |
| 蚬子 | 9.88 | 3.85 |
| 鱼 | 9.37 | 3.66 |
| 猪肉 | 8.61 | 3.36 |
| 烧烤 | 7.85 | 3.06 |
| 羊肉 | 7.35 | 2.87 |
| 扇贝 | 6.59 | 2.57 |
), ArticleFig(id=1241050837221429651, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241034442781815084, language=CN, label=表4, caption=
2014—2023年辽宁省副溶血性弧菌感染具体食品-病原体组合负担排序
, figureFileSmall=null, figureFileBig=null, tableContent=
| 具体食品 | YLDs* | 百分比(%) |
|---|
| 贝类 | 35.97 | 14.03 |
| 虾 | 24.32 | 9.49 |
| 西瓜 | 15.70 | 6.13 |
| 螃蟹 | 13.68 | 5.34 |
| 蚬子 | 9.88 | 3.85 |
| 鱼 | 9.37 | 3.66 |
| 猪肉 | 8.61 | 3.36 |
| 烧烤 | 7.85 | 3.06 |
| 羊肉 | 7.35 | 2.87 |
| 扇贝 | 6.59 | 2.57 |
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