Article(id=1241023858283696851, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202409150, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1725811200000, receivedDateStr=2024-09-09, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773812744923, onlineDateStr=2026-03-18, pubDate=1737734400000, pubDateStr=2025-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773812744923, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773812744923, creator=13701087609, updateTime=1773812744923, updator=13701087609, issue=Issue{id=1241023847537897695, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='2', pageStart='193', pageEnd='384', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773812742361, creator=13701087609, updateTime=1773812823817, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241024189247845056, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241024189247845057, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=376, endPage=380, ext={EN=ArticleExt(id=1241023859235803916, articleId=1241023858283696851, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Prevalence and risk factors of metabolic syndrome among middle-aged and elderly people in Tibet, columnId=1228016569138213037, journalTitle=Modern Preventive Medicine, columnName=Clinical Medicine and Prevention, runingTitle=null, highlight=null, articleAbstract=
Objective To comprehensively understand the incidence of metabolic syndrome (MS) and its potential risk elements in middle-aged and elderly people in Tibet, and to provide a scientific and reliable reference for the development and implementation of precise prevention and control strategies for MS in Tibet.
Methods Between June 2021 and December 2022, 6 286 middle-aged and elderly people were strictly screened in Tibet by multi-stage stratified cluster random sampling. The data were organized and analyzed by using SPSS27.0 software, and the differences in MS prevalence among different groups were compared by using the chi-square test and the trend chi-square test, and further analyses of the factors affecting the prevalence of MS were conducted using logistics regression.
Results Among 6 286 middle-aged and elderly participants, a total of 1 409 patients were screened, with an overall prevalence of metabolic syndrome of 22.41%, the older the age, the higher the prevalence of MS (χ2 = 49.694, P < 0.001); the prevalence of MS in men was 27.8%, higher than that in women, which was 18.21%, with a statistically significant difference (P < 0.001). Multifactorial unconditional logistic regression analysis revealed that the main risk factors for the prevalence of MS were advanced age (OR=2.053, 95% CI: 1.545-2.728) for those aged 70 years and above, a family history of hypertension (OR=2.691, 95% CI: 2.293-3.158), a family history of diabetes (OR=4.480, 95% CI: 2.066-9.716) and a body mass index (BMI)≥24.0 kg/m2 (OR=14.148, 95%CI: 11.778-16.995), however, female (OR=0.508, 95%CI: 0.443-0.584) and alcohol consumption (OR=0.628, 95%CI: 0.487-0.812) were protective factors for the development of MS. In addition, among the various combinations of abnormal components of MS, the aggregation pattern of “abnormal glucose + abnormal blood pressure +central obesity” was the most prevalent, involving a total of 340 cases, with a prevalence rate of 5.41%.
Conclusion The prevalence of MS in middle-aged and elderly people in Tibet is at a high level, in which males, elderly people, people with a family history of hypertension or diabetes, and overweight or obese people should be regarded as the priority targets for MS prevention and control. This study provides a basic reference for the prevention and control of MS in Tibet, so that precise prevention and control measures can be taken according to the high-risk groups.
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目的 了解西藏地区中老年人代谢综合征(MS)的流行状况及其影响因素,为西藏地区制定并实施精准的MS的防控策略提供科学依据。
方法 2021年6月—2022年12月期间在西藏运用多阶段随机抽样的方法抽取6 286名中老年人进行调查, 使用SPSS 27.0软件对数据进行分析,利用χ2检验及趋势性χ2检验进行不同特征群体间的MS患病差异的比较,采用logistics回归模型进行MS患病的影响因素分析。
结果 在6 286名中老年参与者中,筛查出MS患者共计1 409例,总体患病率为22.41%;年龄越大,MS患病率越高(χ2=49.694,P<0.001);男性MS患病率为27.8%,高于女性的18.21%,差异具有统计学意义(P<0.001)。多因素logistic回归分析结果显示,高龄(70岁及以上者OR=2.053,95%CI:1.545~2.728)、高血压家族史(OR=2.691,95%CI:2.293~3.158)、糖尿病家族史(OR=4.480,95%CI:2.066~9.716)以及体质指数(BMI)≥24.0 kg/m2(OR=14.148,95%CI:11.778~16.995)为MS患病的危险因素,女性(OR=0.508,95%CI:0.443~0.584)、饮酒(OR=0.628,95%CI:0.487~0.812)为MS患病的保护因素。“血糖异常 + 血压异常 + 中心性肥胖”是MS异常组分组合中最普遍的聚集模式,患病率为5.41%。
结论 西藏地区中老年人MS患病率相对较高,其中男性、高龄者、具有高血压或糖尿病家族史以及超重肥胖人群应被视为MS防控的优先关注对象。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=7zoYMzAC1ArPcgpJQqp4Rg==, magXml=PsZklOTpIep3keOsUiighg==, pdfUrl=null, pdf=/lvc0FYriSLnzZ01nWTu+w==, pdfFileSize=571492, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=BAysKiE1S4q/1QpFgDr8rw==, mapNumber=null, authorCompany=null, fund=null, authors=
于跃(1989—),女,硕士在读,主管医师,研究方向:慢性非传染性疾病预防与控制
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97(7): e695-e705., articleTitle=Association of metabolic syndrome andits components with risk of stroke recurrence and mortality: a meta-analysis, refAbstract=null)], funds=[Fund(id=1241023865497899222, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, awardId=2021—2022年, language=CN, fundingSource=中央财政转移支付地方卫生计生项目—心血管病高危人群早期筛查与综合干预项目(2021—2022年), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1241023860112413518, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, xref=1., ext=[AuthorCompanyExt(id=1241023860133385042, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, companyId=1241023860112413518, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China), AuthorCompanyExt(id=1241023860141773653, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, companyId=1241023860112413518, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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2.西藏自治区疾病预防控制中心)])], figs=[ArticleFig(id=1241023864684204182, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=EN, label=Table 1, caption=
Prevalence of MS among elderly people with different characteristics in Tibet
, figureFileSmall=null, figureFileBig=null, tableContent=
| 特征 | 总人数 | 患病数 | 患病率 (%) | χ2值 | P |
|---|
| 性别 | | | | 82.072 | <0.001 |
| 男 | 2 750 | 765 | 27.81 | | |
| 女 | 3 536 | 644 | 18.21 | | |
| 年龄(岁) | | | | 49.694a | <0.001 |
| 40~49 | 2 111 | 355 | 16.82 | | |
| 50~59 | 2 310 | 569 | 24.63 | | |
| 60~69 | 1 412 | 354 | 25.07 | | |
| ≥70 | 453 | 131 | 28.92 | | |
| 城乡 | | | | 2.423 | 0.120 |
| 城区 | 929 | 227 | 24.44 | | |
| 农牧区 | 5 357 | 1 182 | 22.06 | | |
| 文化程度 | | | | 3.791 | 0.052 |
| 初中以下 | 949 | 236 | 24.87 | | |
| 初中及以上 | 5 337 | 1 173 | 21.97 | | |
| 家庭年收入>5万 | | | | 0.989 | 0.320 |
| 否 | 5 816 | 1 295 | 22.27 | | |
| 是 | 470 | 114 | 24.26 | | |
| 吸烟 | | | | 2.179 | 0.103 |
| 否 | 5 879 | 1 309 | 22.27 | | |
| 是 | 407 | 100 | 24.57 | | |
| 饮酒 | | | | 5.089 | 0.024 |
| 否 | 5 737 | 1 307 | 22.78 | | |
| 是 | 549 | 102 | 18.58 | | |
| 高血压家族史 | | | | 247.054 | <0.001 |
| 否 | 4 904 | 884 | 18.03 | | |
| 是 | 1 382 | 525 | 37.99 | | |
| 糖尿病家族史 | | | | 53.369 | <0.001 |
| 否 | 6 242 | 1 379 | 22.09 | | |
| 是 | 44 | 30 | 68.18 | | |
| BMI(kg/m2) | | | | 1 127.061 | <0.001 |
| <24 | 3 163 | 154 | 4.89 | | |
| ≥24 | 3 123 | 1 255 | 40.19 | | |
), ArticleFig(id=1241023864776478880, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=CN, label=表1, caption=
西藏不同特征中老年人MS患病情况
, figureFileSmall=null, figureFileBig=null, tableContent=
| 特征 | 总人数 | 患病数 | 患病率 (%) | χ2值 | P |
|---|
| 性别 | | | | 82.072 | <0.001 |
| 男 | 2 750 | 765 | 27.81 | | |
| 女 | 3 536 | 644 | 18.21 | | |
| 年龄(岁) | | | | 49.694a | <0.001 |
| 40~49 | 2 111 | 355 | 16.82 | | |
| 50~59 | 2 310 | 569 | 24.63 | | |
| 60~69 | 1 412 | 354 | 25.07 | | |
| ≥70 | 453 | 131 | 28.92 | | |
| 城乡 | | | | 2.423 | 0.120 |
| 城区 | 929 | 227 | 24.44 | | |
| 农牧区 | 5 357 | 1 182 | 22.06 | | |
| 文化程度 | | | | 3.791 | 0.052 |
| 初中以下 | 949 | 236 | 24.87 | | |
| 初中及以上 | 5 337 | 1 173 | 21.97 | | |
| 家庭年收入>5万 | | | | 0.989 | 0.320 |
| 否 | 5 816 | 1 295 | 22.27 | | |
| 是 | 470 | 114 | 24.26 | | |
| 吸烟 | | | | 2.179 | 0.103 |
| 否 | 5 879 | 1 309 | 22.27 | | |
| 是 | 407 | 100 | 24.57 | | |
| 饮酒 | | | | 5.089 | 0.024 |
| 否 | 5 737 | 1 307 | 22.78 | | |
| 是 | 549 | 102 | 18.58 | | |
| 高血压家族史 | | | | 247.054 | <0.001 |
| 否 | 4 904 | 884 | 18.03 | | |
| 是 | 1 382 | 525 | 37.99 | | |
| 糖尿病家族史 | | | | 53.369 | <0.001 |
| 否 | 6 242 | 1 379 | 22.09 | | |
| 是 | 44 | 30 | 68.18 | | |
| BMI(kg/m2) | | | | 1 127.061 | <0.001 |
| <24 | 3 163 | 154 | 4.89 | | |
| ≥24 | 3 123 | 1 255 | 40.19 | | |
), ArticleFig(id=1241023864856170661, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=EN, label=Table 2, caption=
Assignment of variables in logistic regression analysis
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 变量名称 | 赋值方式 |
|---|
| Y | MS | 否=0;是=1 |
| X1 | 性别 | 男=0;女=1 |
| X2 | 年龄(岁) | 40~49=0;50~59=1;60~69=2;70~=3 |
| X3 | 饮酒 | 否=0;是=1 |
| X4 | 高血压 | 否=0;是=1 |
| X5 | 糖尿病 | 否=0;是=1 |
| X6 | 血脂异常 | 否=0;是=1 |
| X7 | 中心性肥胖 | 否=0;是=1 |
| X8 | BMI≥24 kg/m2 | 否=0;是=1 |
), ArticleFig(id=1241023864940056749, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=CN, label=表2, caption=
logistic回归分析变量赋值情况
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 变量名称 | 赋值方式 |
|---|
| Y | MS | 否=0;是=1 |
| X1 | 性别 | 男=0;女=1 |
| X2 | 年龄(岁) | 40~49=0;50~59=1;60~69=2;70~=3 |
| X3 | 饮酒 | 否=0;是=1 |
| X4 | 高血压 | 否=0;是=1 |
| X5 | 糖尿病 | 否=0;是=1 |
| X6 | 血脂异常 | 否=0;是=1 |
| X7 | 中心性肥胖 | 否=0;是=1 |
| X8 | BMI≥24 kg/m2 | 否=0;是=1 |
), ArticleFig(id=1241023865044914356, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=EN, label=Table 3, caption=
Multifactorial unconditional logistic regression analysis of MS in middle-aged and elderly Tibetans
, figureFileSmall=null, figureFileBig=null, tableContent=
| 因素 | | 参照组 | β | SE | Wald χ2值 | P值 | OR值(95%CI) |
|---|
| 性别 | 女 | 男 | -0.676 | 0.071 | 91.485 | <0.001 | 0.508(0.443~0.584) |
| 年龄(岁) | 50~59 | 40~49 | 0.359 | 0.086 | 17.360 | <0.001 | 1.432(1.209~1.695) |
| 60~69 | | 0.348 | 0.100 | 12.107 | 0.001 | 1.416(1.164~1.723) |
| ≥70 | | 0.719 | 0.145 | 24.583 | <0.001 | 2.053(1.545~2.728) |
| 文化程度 | 初中及以上 | 初中以下 | 0.170 | 0.096 | 3.134 | 0.077 | 1.185(0.982~1.430) |
| 饮酒 | 是 | 否 | -0.464 | 0.130 | 12.628 | <0.001 | 0.628(0.487~0.812) |
| 高血压家族史 | 有 | 无 | 0.990 | 0.082 | 147.047 | <0.001 | 2.691(2.293~3.158) |
| 糖尿病家族史 | 有 | 无 | 1.500 | 0.395 | 14.419 | <0.001 | 4.480(2.066~9.716) |
| BMI≥24 kg/m2 | 是 | 否 | 2.650 | 0.094 | 802.185 | <0.001 | 14.148(11.778~16.995) |
), ArticleFig(id=1241023865141383358, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=CN, label=表3, caption=
西藏中老年人MS的多因素非条件logistic回归分析结果
, figureFileSmall=null, figureFileBig=null, tableContent=
| 因素 | | 参照组 | β | SE | Wald χ2值 | P值 | OR值(95%CI) |
|---|
| 性别 | 女 | 男 | -0.676 | 0.071 | 91.485 | <0.001 | 0.508(0.443~0.584) |
| 年龄(岁) | 50~59 | 40~49 | 0.359 | 0.086 | 17.360 | <0.001 | 1.432(1.209~1.695) |
| 60~69 | | 0.348 | 0.100 | 12.107 | 0.001 | 1.416(1.164~1.723) |
| ≥70 | | 0.719 | 0.145 | 24.583 | <0.001 | 2.053(1.545~2.728) |
| 文化程度 | 初中及以上 | 初中以下 | 0.170 | 0.096 | 3.134 | 0.077 | 1.185(0.982~1.430) |
| 饮酒 | 是 | 否 | -0.464 | 0.130 | 12.628 | <0.001 | 0.628(0.487~0.812) |
| 高血压家族史 | 有 | 无 | 0.990 | 0.082 | 147.047 | <0.001 | 2.691(2.293~3.158) |
| 糖尿病家族史 | 有 | 无 | 1.500 | 0.395 | 14.419 | <0.001 | 4.480(2.066~9.716) |
| BMI≥24 kg/m2 | 是 | 否 | 2.650 | 0.094 | 802.185 | <0.001 | 14.148(11.778~16.995) |
), ArticleFig(id=1241023865263018181, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=EN, label=Table 4, caption=
Aggregation patterns of different abnormal components of MS in middle-aged and elderly Tibetans
, figureFileSmall=null, figureFileBig=null, tableContent=
| MS组合类(种) | 血糖异常 | 血压异常 | 中心性肥胖 | 高TG | 低HDL-C | 患病数 | 患病率(%) |
|---|
| 3 | + | + | + | - | - | 340 | 5.41 |
| 3 | + | + | - | + | - | 100 | 1.59 |
| 3 | + | + | - | - | + | 42 | 0.67 |
| 3 | + | - | + | + | - | 83 | 1.32 |
| 3 | + | - | + | - | + | 49 | 0.78 |
| 3 | + | - | - | + | + | 5 | 0.08 |
| 3 | - | + | + | + | - | 106 | 1.69 |
| 3 | - | + | + | - | + | 158 | 2.51 |
| 3 | - | + | - | + | + | 104 | 1.65 |
| 4 | + | + | + | + | - | 183 | 2.91 |
| 4 | + | + | + | - | + | 134 | 2.13 |
| 4 | + | + | - | + | + | 7 | 0.11 |
| 4 | + | - | + | + | + | 15 | 0.24 |
| 4 | - | + | + | + | + | 40 | 0.64 |
| 5 | + | + | + | + | + | 43 | 0.68 |
), ArticleFig(id=1241023865384653009, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023858283696851, language=CN, label=表4, caption=
西藏中老年人MS不同异常组分聚集模式
, figureFileSmall=null, figureFileBig=null, tableContent=
| MS组合类(种) | 血糖异常 | 血压异常 | 中心性肥胖 | 高TG | 低HDL-C | 患病数 | 患病率(%) |
|---|
| 3 | + | + | + | - | - | 340 | 5.41 |
| 3 | + | + | - | + | - | 100 | 1.59 |
| 3 | + | + | - | - | + | 42 | 0.67 |
| 3 | + | - | + | + | - | 83 | 1.32 |
| 3 | + | - | + | - | + | 49 | 0.78 |
| 3 | + | - | - | + | + | 5 | 0.08 |
| 3 | - | + | + | + | - | 106 | 1.69 |
| 3 | - | + | + | - | + | 158 | 2.51 |
| 3 | - | + | - | + | + | 104 | 1.65 |
| 4 | + | + | + | + | - | 183 | 2.91 |
| 4 | + | + | + | - | + | 134 | 2.13 |
| 4 | + | + | - | + | + | 7 | 0.11 |
| 4 | + | - | + | + | + | 15 | 0.24 |
| 4 | - | + | + | + | + | 40 | 0.64 |
| 5 | + | + | + | + | + | 43 | 0.68 |
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