Article(id=1241023857759408850, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202409330, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1726588800000, receivedDateStr=2024-09-18, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773812744797, onlineDateStr=2026-03-18, pubDate=1737734400000, pubDateStr=2025-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773812744797, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773812744797, creator=13701087609, updateTime=1773812744797, updator=13701087609, issue=Issue{id=1241023847537897695, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='2', pageStart='193', pageEnd='384', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773812742361, creator=13701087609, updateTime=1773812823817, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241024189247845056, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241024189247845057, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=336, endPage=341, ext={EN=ArticleExt(id=1241023859843978042, articleId=1241023857759408850, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Effects and mechanisms between chronic pain and depression for middle-aged and older adults, China, columnId=1228016573156360233, journalTitle=Modern Preventive Medicine, columnName=Disease Control and Prevention, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the effects and mechanisms between chronic pain and depression in middle-aged and older adults in China, and to provide reference for promoting pain management and improving interventions.
Methods 13,253 middle-aged and older adults from the fifth issue of the China Health and Retirement Longitudinal Study (CHARLS) were included. Propensity score matching method, logit model, OLS regression and Bootstrap mediation test were used to explain the mediating effects of subjective life expectancy (SLE), sleep duration and Internet use between chronic pain and depression and the moderating role of social participation.
Results The overall effect size of chronic pain on depression was 0.876 (95%CI=0.781-0.972), with a direct effect of 0.745 (95%CI=0.668-0.822), accounting for 85.05%, and an indirect effect of 0.131 (95%CI=0.094-0.169), accounting for 14.95%. The mediating effects of SLE, sleep duration, and Internet use were 0.087 (95%CI=0.071-0.103), 0.093 (95%CI=0.066-0.121), and -0.049 (95%CI=-0.085--0.013), representing 9.93%, 10.62%, and -5.60% of the total effect respectively. Social participation negatively moderated the relationship between chronic pain and depression(β=-0.095,95%CI=-0.186--0.004).
Conclusion Chronic pain not only directly exacerbates depression in middle-aged and older adults but also indirectly worsens depression through SLE and sleep duration. However, Internet use and social participation can have compensatory and alleviating effects. It is recommended that physical and psychological therapies be emphasized and applied simultaneously, with special attention given to key populations such as women, rural dwellers, and chronic patients. Additionally, “Internet plus healthcare” and grassroots communities should be utilized to enhance pain management and intervention for middle-aged and older adults.
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目的 探讨慢性疼痛对我国中老年人抑郁的影响与机制,为促进中老年人疼痛管理和完善制定干预措施提供参考。
方法 利用中国健康与养老追踪调查第五期数据中13 253名中老年人作为研究对象,运用倾向得分匹配法、logit模型、OLS回归和Bootstrap法解释主观预期寿命、睡眠时间和互联网使用对慢性疼痛影响抑郁的中介效应以及社会参与的调节作用。
结果 慢性疼痛对抑郁的总效应量为0.876(95%CI=0.781~0.972),直接效应为0.745(95%CI=0.668~0.822)占85.05%,间接效应为0.131(95%CI=0.094~0.169)占14.95%。主观预期寿命、睡眠时间和互联网使用的中介效应量分别为0.087(95%CI=0.071~0.103)、0.093(95%CI=0.066~0.121)、-0.049(-0.085~-0.013),占总效应的9.93%、10.62%、-5.60%。社会参与负向调节慢性疼痛与抑郁的关系(β=-0.095,95%CI=-0.186~-0.004)。
结论 慢性疼痛不仅直接影响抑郁,还通过主观预期寿命和睡眠时间间接加剧抑郁,但互联网使用和社会参与能够起到补偿和缓解效果,建议依托“互联网+医疗健康”和基层社区,关注女性、农村、慢性病等重点人群,兼顾物理疗法与心理疗法,强化中老年疼痛管理和干预。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=izvYIC2yvpgpC7duIFQVRg==, magXml=Q/x9ZFQegpSw/Pohr1qfTw==, pdfUrl=null, pdf=URgt4hSQ6xj2s/p3rfJ1TQ==, pdfFileSize=809135, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=AIhb3oMpHVDHMUFBAzYWBQ==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=Kbz13NJG0ql7Kn4lx1QbLw==, mapNumber=null, authorCompany=null, fund=null, authors=
郭胜鹏(1997—),男,博士在读,研究方向:互联网医疗与老年健康
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47(1): 161-169. (In Chinese), articleTitle=The impact of Internet use on depression symptoms among older adults:the mediating role of social networks and the moderating role of urban-rural disparity, refAbstract=null)], funds=[Fund(id=1241023867628605693, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, awardId=2021MS07027, language=CN, fundingSource=内蒙古自治区自然科学基金(2021MS07027), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1241023861307790287, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, xref=1., ext=[AuthorCompanyExt(id=1241023861316178897, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, companyId=1241023861307790287, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Administration and Policy, Renmin University of China, Beijing 100872, China), AuthorCompanyExt(id=1241023861324567507, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, companyId=1241023861307790287, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.中国人民大学公共管理学院,北京 100872)]), AuthorCompany(id=1241023861408453596, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, xref=2., ext=[AuthorCompanyExt(id=1241023861429425119, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, companyId=1241023861408453596, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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Between-group equilibrium test, figureFileSmall=85/WFJcsTp/7iPWR9JsubA==, figureFileBig=AIhb3oMpHVDHMUFBAzYWBQ==, tableContent=null), ArticleFig(id=1241023864805839010, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=CN, label=图1, caption=
组间均衡性检验, figureFileSmall=85/WFJcsTp/7iPWR9JsubA==, figureFileBig=AIhb3oMpHVDHMUFBAzYWBQ==, tableContent=null), ArticleFig(id=1241023865049108663, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=EN, label=Fig.2, caption=
Logit and OLS estimation results weighted with samples from kernel matching outcomes, figureFileSmall=YwNIp7R533jYRfOW/cdRpA==, figureFileBig=7CKHYSLo53xFTDzS3rmIpg==, tableContent=null), ArticleFig(id=1241023865137189053, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=CN, label=图2, caption=
基于核匹配结果对样本加权下的logit和OLS估计结果注:括号内为标准误。*P<0.05,**P<0.01,***P<0.001。
, figureFileSmall=YwNIp7R533jYRfOW/cdRpA==, figureFileBig=7CKHYSLo53xFTDzS3rmIpg==, tableContent=null), ArticleFig(id=1241023865233658052, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=EN, label=Table 1, caption=
Basic information on survey respondents
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| 变量名称 | 变量赋值 | 人数(%)/ |
|---|
| 性别 | 女=0 | 6 529(49.26) |
| 男=1 | 6 724(50.74) |
| 居住地 | 农村=0 | 8 287(62.53) |
| 城镇=1 | 4 966(37.47) |
| 文化程度 | 文盲=1 | 2 232(16.84) |
| 小学=2 | 5 608(42.31) |
| 初中=3 | 3 415(25.77) |
| 高中及以上=4 | 1 998(15.08) |
| 婚姻状况 | 未婚=0 | 1 704(12.86) |
| 已婚=1 | 11 549(87.14) |
| 工作状况 | 未在业=0 | 4 381(33.06) |
| 在业=1 | 8 872(66.94) |
| 子女数量 | 无子女=0 | 185(1.39) |
| 1个=1 | 2 742(20.69) |
| 2个=2 | 5 652(42.65) |
| 3个及以上=3 | 4 674(35.27) |
| 是否吸烟 | 否=0 | 9 599(72.43) |
| 是=1 | 3 654(27.57) |
| 是否喝酒 | 否=0 | 8 066(60.86) |
| 是=1 | 5 187(39.14) |
| 患有慢性病 | 否=0 | 8 401(63.39) |
| 是=1 | 4 852(36.61) |
| 有跌倒经历 | 否=0 | 11 191(84.44) |
| 是=1 | 2 062(15.56) |
| 遭受重大意外伤害 | 否=0 | 12 897(97.31) |
| 是=1 | 356(2.69) |
| 年龄(岁) | 受访者实际年龄,取值范围为[45,98] | 60.314±8.962 |
| 独居状况(对数天) | 一年中独居天数的对数,取值范围为[0,5.209] | 0.894±1.778 |
| 经济状况(对数元) | 家庭人均月消费金额的对数,取值范围为[0,10.714] | 6.340±0.991 |
| ADL(分) | 日常生活活动能力得分,取值范围为[6,24] | 6.464±1.416 |
), ArticleFig(id=1241023865367875789, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=CN, label=表1, caption=
调查对象基本情况
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量名称 | 变量赋值 | 人数(%)/ |
|---|
| 性别 | 女=0 | 6 529(49.26) |
| 男=1 | 6 724(50.74) |
| 居住地 | 农村=0 | 8 287(62.53) |
| 城镇=1 | 4 966(37.47) |
| 文化程度 | 文盲=1 | 2 232(16.84) |
| 小学=2 | 5 608(42.31) |
| 初中=3 | 3 415(25.77) |
| 高中及以上=4 | 1 998(15.08) |
| 婚姻状况 | 未婚=0 | 1 704(12.86) |
| 已婚=1 | 11 549(87.14) |
| 工作状况 | 未在业=0 | 4 381(33.06) |
| 在业=1 | 8 872(66.94) |
| 子女数量 | 无子女=0 | 185(1.39) |
| 1个=1 | 2 742(20.69) |
| 2个=2 | 5 652(42.65) |
| 3个及以上=3 | 4 674(35.27) |
| 是否吸烟 | 否=0 | 9 599(72.43) |
| 是=1 | 3 654(27.57) |
| 是否喝酒 | 否=0 | 8 066(60.86) |
| 是=1 | 5 187(39.14) |
| 患有慢性病 | 否=0 | 8 401(63.39) |
| 是=1 | 4 852(36.61) |
| 有跌倒经历 | 否=0 | 11 191(84.44) |
| 是=1 | 2 062(15.56) |
| 遭受重大意外伤害 | 否=0 | 12 897(97.31) |
| 是=1 | 356(2.69) |
| 年龄(岁) | 受访者实际年龄,取值范围为[45,98] | 60.314±8.962 |
| 独居状况(对数天) | 一年中独居天数的对数,取值范围为[0,5.209] | 0.894±1.778 |
| 经济状况(对数元) | 家庭人均月消费金额的对数,取值范围为[0,10.714] | 6.340±0.991 |
| ADL(分) | 日常生活活动能力得分,取值范围为[6,24] | 6.464±1.416 |
), ArticleFig(id=1241023865476927698, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=EN, label=Table 2, caption=
Logit regression results with chronic pain as the dependent variable
, figureFileSmall=null, figureFileBig=null, tableContent=
| 研究变量 | B | SE | Wald χ2值 | OR(95%CI) |
|---|
| 性别(以女为参照) | -0.698c | 0.049 | -14.18 | 0.498(0.452,0.548) |
| 年龄 | -0.002 | 0.003 | -0.84 | 0.998(0.993,1.003) |
| 居住地(以农村为参照) | -0.119b | 0.044 | -2.68 | 0.888(0.814,0.969) |
| 文化程度(以高中及以上为参照) | | | | |
| 文盲 | 0.165a | 0.075 | 2.21 | 1.180(1.019,1.366) |
| 小学 | 0.245c | 0.059 | 4.18 | 1.278(1.139,1.433) |
| 初中 | 0.125a | 0.060 | 2.08 | 1.133(1.007,1.274) |
| 婚姻状况(以未婚为参照) | 0.112 | 0.066 | 1.71 | 1.119(0.983,1.272) |
| 工作状况(以未在业为参照) | 0.071 | 0.046 | 1.54 | 1.074(0.981,1.176) |
| 独居状况 | 0.020 | 0.012 | 1.73 | 1.020(0.997,1.044) |
| 经济状况 | 0.001 | 0.021 | 0.04 | 1.001(0.961,1.043) |
| 子女数量(以3个及以上为参照) | | | | |
| 无子女 | -0.023 | 0.163 | -0.14 | 0.978(0.711,1.345) |
| 1个 | -0.094 | 0.058 | -1.63 | 0.910(0.812,1.019) |
| 2个 | 0.011 | 0.046 | 0.25 | 1.011(0.925,1.106) |
| 是否吸烟(以不吸烟为参照) | 0.052 | 0.048 | 1.09 | 1.054(0.959,1.158) |
| 是否喝酒(以不喝酒为参照) | -0.021 | 0.043 | -0.49 | 0.979(0.901,1.065) |
| ADL | 0.353c | 0.025 | 14.04 | 1.423(1.354,1.495) |
| 患有慢性病(以无慢性病为参照) | 0.599c | 0.040 | 15.12 | 1.821(1.685,1.968) |
| 有跌倒经历(以无跌倒为参照) | 0.740c | 0.059 | 12.63 | 2.097(1.869,2.352) |
| 遭受重大意外伤害(以未遭受为参照) | 0.461c | 0.128 | 3.61 | 1.586(1.235,2.036) |
| 常数项 | -2.026 | 0.293 | -6.90 | 0.132(0.074,0.234) |
), ArticleFig(id=1241023865565008089, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=CN, label=表2, caption=
以慢性疼痛为因变量的logit回归结果
, figureFileSmall=null, figureFileBig=null, tableContent=
| 研究变量 | B | SE | Wald χ2值 | OR(95%CI) |
|---|
| 性别(以女为参照) | -0.698c | 0.049 | -14.18 | 0.498(0.452,0.548) |
| 年龄 | -0.002 | 0.003 | -0.84 | 0.998(0.993,1.003) |
| 居住地(以农村为参照) | -0.119b | 0.044 | -2.68 | 0.888(0.814,0.969) |
| 文化程度(以高中及以上为参照) | | | | |
| 文盲 | 0.165a | 0.075 | 2.21 | 1.180(1.019,1.366) |
| 小学 | 0.245c | 0.059 | 4.18 | 1.278(1.139,1.433) |
| 初中 | 0.125a | 0.060 | 2.08 | 1.133(1.007,1.274) |
| 婚姻状况(以未婚为参照) | 0.112 | 0.066 | 1.71 | 1.119(0.983,1.272) |
| 工作状况(以未在业为参照) | 0.071 | 0.046 | 1.54 | 1.074(0.981,1.176) |
| 独居状况 | 0.020 | 0.012 | 1.73 | 1.020(0.997,1.044) |
| 经济状况 | 0.001 | 0.021 | 0.04 | 1.001(0.961,1.043) |
| 子女数量(以3个及以上为参照) | | | | |
| 无子女 | -0.023 | 0.163 | -0.14 | 0.978(0.711,1.345) |
| 1个 | -0.094 | 0.058 | -1.63 | 0.910(0.812,1.019) |
| 2个 | 0.011 | 0.046 | 0.25 | 1.011(0.925,1.106) |
| 是否吸烟(以不吸烟为参照) | 0.052 | 0.048 | 1.09 | 1.054(0.959,1.158) |
| 是否喝酒(以不喝酒为参照) | -0.021 | 0.043 | -0.49 | 0.979(0.901,1.065) |
| ADL | 0.353c | 0.025 | 14.04 | 1.423(1.354,1.495) |
| 患有慢性病(以无慢性病为参照) | 0.599c | 0.040 | 15.12 | 1.821(1.685,1.968) |
| 有跌倒经历(以无跌倒为参照) | 0.740c | 0.059 | 12.63 | 2.097(1.869,2.352) |
| 遭受重大意外伤害(以未遭受为参照) | 0.461c | 0.128 | 3.61 | 1.586(1.235,2.036) |
| 常数项 | -2.026 | 0.293 | -6.90 | 0.132(0.074,0.234) |
), ArticleFig(id=1241023865653088480, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=EN, label=Table 3, caption=
PSM results of chronic pain on depression
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| 研究变量 | 处理组 | 对照组 | 平均处理效应 | 标准误 | t值 |
|---|
| 抑郁 | | | | | |
| k近邻匹配 | 0.461 | 0.267 | 0.194c | 0.012 | 16.00 |
| 卡尺匹配 | 0.461 | 0.275 | 0.186c | 0.009 | 20.33 |
| 核匹配 | 0.461 | 0.276 | 0.185c | 0.009 | 20.26 |
| 主观预期寿命 | | | | | |
| k近邻匹配 | 2.901 | 3.266 | -0.365c | 0.033 | -11.11 |
| 卡尺匹配 | 2.901 | 3.263 | -0.362c | 0.025 | -14.75 |
| 核匹配 | 2.901 | 3.263 | -0.362c | 0.025 | -14.74 |
| 睡眠时间 | | | | | |
| k近邻匹配 | 6.013 | 6.518 | -0.505c | 0.045 | -11.27 |
| 卡尺匹配 | 6.013 | 6.511 | -0.498c | 0.033 | -15.01 |
| 核匹配 | 6.013 | 6.511 | -0.498c | 0.033 | -14.98 |
| 互联网使用 | | | | | |
| k近邻匹配 | 0.459 | 0.429 | 0.030b | 0.009 | 2.54 |
| 卡尺匹配 | 0.459 | 0.430 | 0.029b | 0.010 | 2.81 |
| 核匹配 | 0.459 | 0.431 | 0.028b | 0.010 | 2.77 |
), ArticleFig(id=1241023865753751780, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=CN, label=表3, caption=
慢性疼痛对抑郁的PSM结果
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| 研究变量 | 处理组 | 对照组 | 平均处理效应 | 标准误 | t值 |
|---|
| 抑郁 | | | | | |
| k近邻匹配 | 0.461 | 0.267 | 0.194c | 0.012 | 16.00 |
| 卡尺匹配 | 0.461 | 0.275 | 0.186c | 0.009 | 20.33 |
| 核匹配 | 0.461 | 0.276 | 0.185c | 0.009 | 20.26 |
| 主观预期寿命 | | | | | |
| k近邻匹配 | 2.901 | 3.266 | -0.365c | 0.033 | -11.11 |
| 卡尺匹配 | 2.901 | 3.263 | -0.362c | 0.025 | -14.75 |
| 核匹配 | 2.901 | 3.263 | -0.362c | 0.025 | -14.74 |
| 睡眠时间 | | | | | |
| k近邻匹配 | 6.013 | 6.518 | -0.505c | 0.045 | -11.27 |
| 卡尺匹配 | 6.013 | 6.511 | -0.498c | 0.033 | -15.01 |
| 核匹配 | 6.013 | 6.511 | -0.498c | 0.033 | -14.98 |
| 互联网使用 | | | | | |
| k近邻匹配 | 0.459 | 0.429 | 0.030b | 0.009 | 2.54 |
| 卡尺匹配 | 0.459 | 0.430 | 0.029b | 0.010 | 2.81 |
| 核匹配 | 0.459 | 0.431 | 0.028b | 0.010 | 2.77 |
), ArticleFig(id=1241023865892163818, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=EN, label=Table 4, caption=
Results of Bootstrap mediation effect test
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| 效应类型 | 效应量 | SE | 95%CI | 效应占比 (%) |
|---|
| 直接效应 | 0.745c | 0.039 | (0.668,0.822) | 85.05 |
| 间接效应 | 0.131c | 0.019 | (0.094,0.169) | 14.95 |
| 主观预期寿命 | 0.087c | 0.008 | (0.071,0.103) | 9.93 |
| 睡眠时间 | 0.093c | 0.014 | (0.066,0.121) | 10.62 |
| 互联网使用 | -0.049b | 0.018 | (-0.085,-0.013) | -5.60 |
| 总效应 | 0.876c | 0.049 | (0.781,0.972) | 100.00 |
), ArticleFig(id=1241023866055741680, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023857759408850, language=CN, label=表4, caption=
Bootstrap中介效应检验结果
, figureFileSmall=null, figureFileBig=null, tableContent=
| 效应类型 | 效应量 | SE | 95%CI | 效应占比 (%) |
|---|
| 直接效应 | 0.745c | 0.039 | (0.668,0.822) | 85.05 |
| 间接效应 | 0.131c | 0.019 | (0.094,0.169) | 14.95 |
| 主观预期寿命 | 0.087c | 0.008 | (0.071,0.103) | 9.93 |
| 睡眠时间 | 0.093c | 0.014 | (0.066,0.121) | 10.62 |
| 互联网使用 | -0.049b | 0.018 | (-0.085,-0.013) | -5.60 |
| 总效应 | 0.876c | 0.049 | (0.781,0.972) | 100.00 |
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