Article(id=1241023855205077584, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202407510, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1722182400000, receivedDateStr=2024-07-29, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773812744189, onlineDateStr=2026-03-18, pubDate=1737734400000, pubDateStr=2025-01-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773812744189, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773812744189, creator=13701087609, updateTime=1773812744189, updator=13701087609, issue=Issue{id=1241023847537897695, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='2', pageStart='193', pageEnd='384', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773812742361, creator=13701087609, updateTime=1773812823817, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241024189247845056, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241024189247845057, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241023847537897695, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=310, endPage=314, ext={EN=ArticleExt(id=1241023856794718904, articleId=1241023855205077584, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Relationship between pain status and subjective life expectancy in elderly patients with chronic diseases: the chain mediating effect of daily activity ability and depression, columnId=1228016572451718132, journalTitle=Modern Preventive Medicine, columnName=Health and Social Behavior, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the mediating effects of daily activity ability and depression on pain status and subjective life expectancy in elderly patients with chronic diseases, and to provide suggestions and references for active aging.
Methods Based on The China Health and Retirement Longitudinal Study (CHARLS) 2020 data, 5 768 patients with chronic diseases aged ≥60 years were selected as the study subjects, and Spearman correlation analysis was used to explore the correlation between pain, ability to perform activities of daily living, depression, and subjective life expectancy, and PROCESS 4.1 program Model 6 was used to construct the chain-mediated model.
Results Pain was positively correlated with impaired daily activity ability and depression (r=0.399, P<0.001; r=0.370, P<0.001), was negatively correlated with subjective life expectancy (r=-0.221, P<0.001); The mediating effects of daily activity ability and depression on pain and subjective life expectancy were significant, with simple mediating effects of -0.023 (95%CI: -0.031 to -0.016) and -0.042 (95%CI: -0.049 to -0.034), respectively. The chain mediation effect was -0.013(95%CI: -0.016 to -0.010). The total mediating effect of daily activity ability and depression on pain and subjective life expectancy was -0.078, accounting for 57.78%.
Conclusion There is a chain mediated effect between daily activity ability and depression on pain status and subjective life expectancy in elderly patients with chronic diseases. With the popularization of primary medical and health services, the family doctor service team needs to improve the comprehensive management of elderly patients with chronic diseases, improve the subjective well-being of elderly patients with chronic diseases from pain management, daily activity intervention, depression regulation and other aspects, and prolong the subjective life expectancy.
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目的 探讨日常活动能力与抑郁在老年慢性病患者疼痛状况与主观预期寿命间的中介作用,为积极老龄化提供建议与参考。
方法 基于中国健康与养老追踪调查(CHARLS)2020年数据,选取≥60岁慢性病患者5 768名作为研究对象,运用Spearman相关分析方法探讨疼痛、日常活动能力、抑郁和主观预期寿命之间的相关性,采用PROCESS 4.1程序Model 6构建链式中介模型。
结果 疼痛与日常活动能力受损、抑郁呈正相关(r=0.399,P<0.001;r=0.370,P<0.001),与主观预期寿命呈负相关(r=-0.221,P<0.001);日常活动能力与抑郁在疼痛与主观预期寿命之间的中介效应显著,简单中介效应值分别为-0.023(95%CI:-0.031~-0.016)和-0.042(95%CI:-0.049~-0.034),链式中介效应为-0.013(95%CI:-0.016~-0.010)。日常活动能力和抑郁在疼痛与主观预期寿命间的总中介效应值为-0.078,效应占比为57.78%。
结论 日常活动能力与抑郁在老年慢性病患者疼痛状况与主观预期寿命间存在链式中介效应。随着基层医疗卫生服务的普及,家庭医生服务团队需要提高对老年慢性病患者综合管理力度,从疼痛管理、日常活动能力干预、抑郁调节等多方面提升老年慢性病患者的主观幸福感,延长主观预期寿命。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=fLZ/FcoSHLNs7MrkLHGI8g==, magXml=gNnAZZu20yDI4S2CihXCaA==, pdfUrl=null, pdf=OD86HN85J/fYvsEf88lU3Q==, pdfFileSize=700206, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=AhzXI2oLi4gbFCaia5Z46g==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=gI2iOT8jGwwulqqSqko4wg==, mapNumber=null, authorCompany=null, fund=null, authors=
张宝轩(2001—),男,硕士在读,研究方向:卫生管理与政策研究
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1.山东第二医科大学管理学院,山东 潍坊 261053
2.“健康山东”重大社会风险预测与治理协同创新中心
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1.山东第二医科大学管理学院,山东 潍坊 261053
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| 人口学特征 | 样本例数(n) | 构成比(%) | 主观预期寿命 ( ) | t(F)值 | P值 |
|---|
| 性别 | | | | 2.379 | 0.017 |
| 男 | 2 948 | 51.1 | 2.89±1.23 | | |
| 女 | 2 820 | 48.9 | 2.81±1.27 | | |
| 年龄(岁) | | | | 176.937a | <0.001 |
| 60~69 | 3 782 | 65.6 | 3.06±1.24 | | |
| 70~79 | 1 710 | 29.6 | 2.50±1.20 | | |
| ≥80 | 276 | 4.8 | 2.11±1.04 | | |
| 居住地 | | | | 8.882 | <0.001 |
| 城镇 | 2 035 | 35.3 | 3.05±1.24 | | |
| 农村 | 3 733 | 64.7 | 2.74±1.25 | | |
| 婚姻状态 | | | | 7.021 | <0.001 |
| 在婚 | 4 638 | 80.4 | 2.91±1.24 | | |
| 非在婚 | 1 130 | 19.6 | 2.61±1.27 | | |
| 文化程度 | | | | 61.604a | <0.001 |
| 文盲或半文盲 | 2 714 | 47.1 | 2.71±1.27 | | |
| 小学毕业 | 1 329 | 23.0 | 2.77±1.22 | | |
| 初中及以上 | 1 725 | 29.9 | 3.12±1.20 | | |
| 自评健康 | | | | 18.381 | <0.001 |
| 好 | 1 024 | 17.8 | 3.48±1.21 | | |
| 差 | 4 744 | 82.2 | 2.71±1.22 | | |
| 合计 | 5 768 | 100.0 | 2.85±1.25 | | |
), ArticleFig(id=1241023866047353071, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=CN, label=表1, caption=
研究对象基本情况
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| 人口学特征 | 样本例数(n) | 构成比(%) | 主观预期寿命 ( ) | t(F)值 | P值 |
|---|
| 性别 | | | | 2.379 | 0.017 |
| 男 | 2 948 | 51.1 | 2.89±1.23 | | |
| 女 | 2 820 | 48.9 | 2.81±1.27 | | |
| 年龄(岁) | | | | 176.937a | <0.001 |
| 60~69 | 3 782 | 65.6 | 3.06±1.24 | | |
| 70~79 | 1 710 | 29.6 | 2.50±1.20 | | |
| ≥80 | 276 | 4.8 | 2.11±1.04 | | |
| 居住地 | | | | 8.882 | <0.001 |
| 城镇 | 2 035 | 35.3 | 3.05±1.24 | | |
| 农村 | 3 733 | 64.7 | 2.74±1.25 | | |
| 婚姻状态 | | | | 7.021 | <0.001 |
| 在婚 | 4 638 | 80.4 | 2.91±1.24 | | |
| 非在婚 | 1 130 | 19.6 | 2.61±1.27 | | |
| 文化程度 | | | | 61.604a | <0.001 |
| 文盲或半文盲 | 2 714 | 47.1 | 2.71±1.27 | | |
| 小学毕业 | 1 329 | 23.0 | 2.77±1.22 | | |
| 初中及以上 | 1 725 | 29.9 | 3.12±1.20 | | |
| 自评健康 | | | | 18.381 | <0.001 |
| 好 | 1 024 | 17.8 | 3.48±1.21 | | |
| 差 | 4 744 | 82.2 | 2.71±1.22 | | |
| 合计 | 5 768 | 100.0 | 2.85±1.25 | | |
), ArticleFig(id=1241023867582468344, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=EN, label=Table 2, caption=
Correlation analysis of pain, daily activity ability, depression and subjective life expectancy
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| 变量 | 疼痛 | 日常活动能力 | 抑郁 | 主观预期寿命 |
|---|
| 疼痛 | 1.000 | | | |
| 日常活动能力 | 0.399a | 1.000 | | |
| 抑郁 | 0.370a | 0.417a | 1.000 | |
| 主观预期寿命 | -0.221a | -0.293a | -0.326a | 1.000 |
), ArticleFig(id=1241023867678937344, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=CN, label=表2, caption=
疼痛、日常活动能力、抑郁、主观预期寿命相关性分析
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| 变量 | 疼痛 | 日常活动能力 | 抑郁 | 主观预期寿命 |
|---|
| 疼痛 | 1.000 | | | |
| 日常活动能力 | 0.399a | 1.000 | | |
| 抑郁 | 0.370a | 0.417a | 1.000 | |
| 主观预期寿命 | -0.221a | -0.293a | -0.326a | 1.000 |
), ArticleFig(id=1241023867796377862, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=EN, label=Table 3, caption=
Test table of mediation effect
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| 变量 | 模型1 主观预期寿命 | 模型2 日常活动能力 | 模型3 抑郁 | 模型4 主观预期寿命 |
|---|
| β | t | β | t | β | t | β | t |
|---|
| 疼痛 | -0.135 | -11.478 | 0.893 | 22.297 | 1.367 | 18.901 | -0.057 | -4.631 |
| 日常活动能力 | | | | | 0.481 | 21.076 | -0.026 | -6.695 |
| 抑郁 | | | | | | | -0.030 | -13.974 |
| R2 | 0.150 | 0.141 | 0.290 | 0.194 |
| F | 145.133a | 135.142a | 294.641a | 153.693a |
), ArticleFig(id=1241023867947372814, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=CN, label=表3, caption=
中介效应检验表
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 模型1 主观预期寿命 | 模型2 日常活动能力 | 模型3 抑郁 | 模型4 主观预期寿命 |
|---|
| β | t | β | t | β | t | β | t |
|---|
| 疼痛 | -0.135 | -11.478 | 0.893 | 22.297 | 1.367 | 18.901 | -0.057 | -4.631 |
| 日常活动能力 | | | | | 0.481 | 21.076 | -0.026 | -6.695 |
| 抑郁 | | | | | | | -0.030 | -13.974 |
| R2 | 0.150 | 0.141 | 0.290 | 0.194 |
| F | 145.133a | 135.142a | 294.641a | 153.693a |
), ArticleFig(id=1241023868077396240, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=EN, label=Table 4, caption=
The mediation effect of daily activity ability and depression on pain and subjectivelife expectancy was tested
, figureFileSmall=null, figureFileBig=null, tableContent=
| 类别 | 效应值(95%CI) | 标准误 | 效应占比(%) |
|---|
| 总效应 | -0.135(-0.158~-0.112) | 0.012 | 100.00 |
| 直接效应 | -0.057(-0.081~-0.033) | 0.012 | 42.22 |
| 总中介效应 | -0.078(-0.088~-0.068) | 0.005 | 57.78 |
| 路径1 | -0.023(-0.031~-0.016) | 0.004 | 17.04 |
| 路径2 | -0.042(-0.049~-0.034) | 0.004 | 31.11 |
| 路径3 | -0.013(-0.016~-0.010) | 0.001 | 9.63 |
), ArticleFig(id=1241023868240974103, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241023855205077584, language=CN, label=表4, caption=
日常活动能力与抑郁在疼痛与主观预期寿命间的Bootstrap中介效应检验
, figureFileSmall=null, figureFileBig=null, tableContent=
| 类别 | 效应值(95%CI) | 标准误 | 效应占比(%) |
|---|
| 总效应 | -0.135(-0.158~-0.112) | 0.012 | 100.00 |
| 直接效应 | -0.057(-0.081~-0.033) | 0.012 | 42.22 |
| 总中介效应 | -0.078(-0.088~-0.068) | 0.005 | 57.78 |
| 路径1 | -0.023(-0.031~-0.016) | 0.004 | 17.04 |
| 路径2 | -0.042(-0.049~-0.034) | 0.004 | 31.11 |
| 路径3 | -0.013(-0.016~-0.010) | 0.001 | 9.63 |
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