Article(id=1241022952100131083, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241022939957621542, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202410321, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1729526400000, receivedDateStr=2024-10-22, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773812528872, onlineDateStr=2026-03-18, pubDate=1742832000000, pubDateStr=2025-03-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773812528872, onlineIssueDateStr=2026-03-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773812528872, creator=13701087609, updateTime=1773812528872, updator=13701087609, issue=Issue{id=1241022939957621542, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='6', pageStart='961', pageEnd='1152', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773812525976, creator=13701087609, updateTime=1773815469296, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241035285174219432, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241022939957621542, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241035285174219433, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241022939957621542, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1105, endPage=1110, ext={EN=ArticleExt(id=1241022952494395698, articleId=1241022952100131083, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Chain mediating role of adult socioeconomic status and depression in the relationship between childhood friendship experience and cognitive function in older adults, columnId=1228016572451718132, journalTitle=Modern Preventive Medicine, columnName=Health and Social Behavior, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the chain mediating roles of adult socioeconomic status and depression in the relationship between childhood friendship experiences and cognitive function in the elderly.
Methods Based on the panel data of China Health and Retirement Tracking Survey (CHARLS) in 2014, 2018, and 2020, Partial correlation analysis was used to explore the correlation among childhood friendship experience, adult socioeconomic status, depression, and cognitive function of the elderly. The SPSS’s Process 4.1macro program was used to analyze the chain mediation effect, and Bootstrap method was used to verify the mediation variables.
Results The direct effect of childhood friendship experiences on cognitive function in the elderly was significant(β=0.226, 95% CI: 0.109-0.343). The simple mediating effects of adult socioeconomic status and depression between childhood friendship experiences and cognitive function were significant (β=0.095, 95% CI: 0.067-0.126; β=0.023,95% CI:0.009-0.040). The chain mediating effect of adult socioeconomic status and depression between childhood friendship experiences and cognitive function was significant (β=0.006, 95% CI:0.003-0.010). The total mediating effect and the chain mediating effect respectively account for 35.33% and 1.71% of the total effect.
Conclusion Childhood friendship experience can directly and positively influence cognitive function in the elderly, and also can influence cognitive function in the elderly through the separate and chain mediating effects of socioeconomic status and depression in adulthood.
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目的 探究成年期社会经济地位和抑郁在童年友谊经历与老年人认知功能间的中介作用。
方法 本文运用中国健康与养老追踪调查(CHARLS)2014、2018、2020年面板数据,运用偏相关分析法探究童年友谊经历、成年期社会经济地位、抑郁以及老年人认知功能间的相关性,使用SPSS的Process 4.1宏程序进行链式中介效应分析,并用Bootstrap法进行中介变量验证。
结果 童年友谊经历对老年人认知功能的直接效应显著(β=0.226,95% CI:0.109~0.343),成年期社会经济地位和抑郁在童年友谊经历和老年人认知功能间的单独中介效应显著(β=0.095,95% CI:0.067~0.126;β=0.023,95% CI:0.009~0.040),成年期社会经济地位和抑郁在童年友谊经历和老年人认知功能间的链式中介效应显著(β=0.006,95% CI:0.003~0.010),总中介效应和链式中介效应在总效应中分别占比35.33%和1.71%。
结论 童年友谊经历能够直接正向影响老年人认知功能,也可以通过成年期社会经济地位和抑郁的单独和链式中介作用影响老年人认知功能。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=jb/YrQcQtUELR8NJF29psg==, magXml=p7Otm85Zihg4qBJY7kMRoQ==, pdfUrl=null, pdf=1rjBwZZZA5Y0CmlWut75RA==, pdfFileSize=744644, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=ReKNC/2q8g5Dit546Ms3vw==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=J2G1cDnHm3mu5cgBbefi3A==, mapNumber=null, authorCompany=null, fund=null, authors=
王冉(2001—),女,硕士在读,研究方向:公共卫生与社区管理
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2024. (In Chinese), articleTitle=The impact of childhood social isolation on health-related quality of life in middle-aged and older adults: mechanisms of action of socioeconomic status, refAbstract=null)], funds=[Fund(id=1241022965131834314, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, awardId=71774119, language=CN, fundingSource=国家自然科学基金项目(71774119), fundOrder=null, country=null), Fund(id=1241022965203137486, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, awardId=SDYJSJGC2023067, language=CN, fundingSource=山东省研究生教育教学改革研究项目(SDYJSJGC2023067), fundOrder=null, country=null), Fund(id=1241022965303800784, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, awardId=ZR2023MG019, language=CN, fundingSource=山东省自然科学基金面上项目(ZR2023MG019), fundOrder=null, country=null), Fund(id=1241022965366715348, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, awardId=ZR2023MG004, language=CN, fundingSource=山东省自然科学基金面上项目(ZR2023MG004), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1241022956533510703, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, xref=1., ext=[AuthorCompanyExt(id=1241022956638368315, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, companyId=1241022956533510703, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Shandong Second Medical University, Weifang, Shandong 261053, China), AuthorCompanyExt(id=1241022956659339839, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, companyId=1241022956533510703, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.山东第二医科大学公共卫生学院,山东 潍坊 261053)]), AuthorCompany(id=1241022956760003141, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, xref=2., ext=[AuthorCompanyExt(id=1241022956772586055, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, companyId=1241022956760003141, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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Sample screening flow chart, figureFileSmall=cYiTZ2F813Xf7alZYDR3+A==, figureFileBig=ReKNC/2q8g5Dit546Ms3vw==, tableContent=null), ArticleFig(id=1241022962300679035, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=CN, label=图1, caption=
样本筛选流程图, figureFileSmall=cYiTZ2F813Xf7alZYDR3+A==, figureFileBig=ReKNC/2q8g5Dit546Ms3vw==, tableContent=null), ArticleFig(id=1241022962669777808, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=EN, label=Fig.2, caption=
Diagram of the chain mediation effect model, figureFileSmall=/76K48wmSO61TZ4Vp8LyPA==, figureFileBig=CSR6REZtdqZ02x1VadzytQ==, tableContent=null), ArticleFig(id=1241022962770441107, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=CN, label=图2, caption=
链式中介效应模型图注:*表示P<0.05。
, figureFileSmall=/76K48wmSO61TZ4Vp8LyPA==, figureFileBig=CSR6REZtdqZ02x1VadzytQ==, tableContent=null), ArticleFig(id=1241022962929824668, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=EN, label=Table 1, caption=
Demographic characteristics
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 选项 | 频数(%) | 认知功能得分( ) | t/F值 | P值 |
|---|
| 年龄(岁) | 60~69 | 1 825(67.72) | 9.33±2.46 | 22.007 | <0.001 |
| 70~79 | 781(28.98) | 8.87±2.61 | | |
| ≥80 | 89(3.30) | 7.83±2.35 | | |
| 性别 | 男 | 1 652(61.30) | 9.19±2.53 | 0.984 | 0.325 |
| 女 | 1 043(38.70) | 9.09±2.52 | | |
| 婚姻状况 | 已婚 | 2 171(80.56) | 9.21±2.53 | 3.467 | 0.008 |
| 分居 | 122(4.53) | 8.84±2.42 | | |
| 离异 | 24(0.89) | 10.31±2.01 | | |
| 丧偶 | 370(13.73) | 8.83±2.53 | | |
| 单身 | 8(0.30) | 8.56±2.78 | | |
| 与同龄人相比16岁前自评健康状况 | 好很多 | 494(18.33) | 8.96±2.39 | 3.949 | 0.003 |
| 好一些 | 612(22.71) | 9.33±2.49 | | |
| 差不多 | 1 291(47.91) | 9.11±2.56 | | |
| 差一点 | 199(7.38) | 9.59±2.43 | | |
| 差很多 | 99(3.67) | 8.68±2.87 | | |
| 慢性病种类(种) | 0 | 1 689(62.67) | 9.19±2.55 | 1.515 | 0.195 |
| 1 | 661(24.53) | 9.17±2.45 | | |
| 2 | 236(8.76) | 9.07±2.51 | | |
| 3 | 77(2.86) | 8.78±2.47 | | |
| ≥4 | 32(1.19) | 8.28±2.65 | | |
| 睡眠时间 | 7~8 h | 883(32.76) | 9.24±2.45 | -1.344 | 0.179 |
| 其他 | 1 812(67.24) | 9.10±2.55 | | |
| 饮酒 | 是 | 1 140(42.30) | 9.29±2.47 | -2.417 | 0.016 |
| 否 | 1 555(57.70) | 9.05±2.55 | | |
| 吸烟 | 是 | 1 492(55.36) | 9.16±2.52 | -0.218 | 0.828 |
| 否 | 1 203(44.64) | 9.14±2.52 | | |
), ArticleFig(id=1241022963005322144, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=CN, label=表1, caption=
人口学特征
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 选项 | 频数(%) | 认知功能得分( ) | t/F值 | P值 |
|---|
| 年龄(岁) | 60~69 | 1 825(67.72) | 9.33±2.46 | 22.007 | <0.001 |
| 70~79 | 781(28.98) | 8.87±2.61 | | |
| ≥80 | 89(3.30) | 7.83±2.35 | | |
| 性别 | 男 | 1 652(61.30) | 9.19±2.53 | 0.984 | 0.325 |
| 女 | 1 043(38.70) | 9.09±2.52 | | |
| 婚姻状况 | 已婚 | 2 171(80.56) | 9.21±2.53 | 3.467 | 0.008 |
| 分居 | 122(4.53) | 8.84±2.42 | | |
| 离异 | 24(0.89) | 10.31±2.01 | | |
| 丧偶 | 370(13.73) | 8.83±2.53 | | |
| 单身 | 8(0.30) | 8.56±2.78 | | |
| 与同龄人相比16岁前自评健康状况 | 好很多 | 494(18.33) | 8.96±2.39 | 3.949 | 0.003 |
| 好一些 | 612(22.71) | 9.33±2.49 | | |
| 差不多 | 1 291(47.91) | 9.11±2.56 | | |
| 差一点 | 199(7.38) | 9.59±2.43 | | |
| 差很多 | 99(3.67) | 8.68±2.87 | | |
| 慢性病种类(种) | 0 | 1 689(62.67) | 9.19±2.55 | 1.515 | 0.195 |
| 1 | 661(24.53) | 9.17±2.45 | | |
| 2 | 236(8.76) | 9.07±2.51 | | |
| 3 | 77(2.86) | 8.78±2.47 | | |
| ≥4 | 32(1.19) | 8.28±2.65 | | |
| 睡眠时间 | 7~8 h | 883(32.76) | 9.24±2.45 | -1.344 | 0.179 |
| 其他 | 1 812(67.24) | 9.10±2.55 | | |
| 饮酒 | 是 | 1 140(42.30) | 9.29±2.47 | -2.417 | 0.016 |
| 否 | 1 555(57.70) | 9.05±2.55 | | |
| 吸烟 | 是 | 1 492(55.36) | 9.16±2.52 | -0.218 | 0.828 |
| 否 | 1 203(44.64) | 9.14±2.52 | | |
), ArticleFig(id=1241022963105985447, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=EN, label=Table 2, caption=
Correlation coefficient matrix
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 童年期友谊经历 | 成年期社会经济地位 | 抑郁 | 认知功能 |
|---|
| 童年期友谊经历 | 1.000 | | | |
| 成年期社会经济地位 | 0.212a | 1.000 | | |
| 抑郁 | -0.120a | -0.131a | 1.000 | |
| 认知功能 | 0.114a | 0.178a | -0.106a | 1.000 |
), ArticleFig(id=1241022963219231660, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=CN, label=表2, caption=
相关系数矩阵
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 童年期友谊经历 | 成年期社会经济地位 | 抑郁 | 认知功能 |
|---|
| 童年期友谊经历 | 1.000 | | | |
| 成年期社会经济地位 | 0.212a | 1.000 | | |
| 抑郁 | -0.120a | -0.131a | 1.000 | |
| 认知功能 | 0.114a | 0.178a | -0.106a | 1.000 |
), ArticleFig(id=1241022964729181108, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=EN, label=Table 3, caption=
Results of regression analysis by multiple intermediary models
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 模型1:成年期社会经济地位 | 模型2:抑郁 | 模型3:认知功能 |
|---|
| β |  | t | β |  | t | β |  | t |
|---|
| 常量 | 4.172 | 0.124 | 33.630a | 12.689 | 0.623 | 20.370a | 8.417 | 0.285 | 29.535a |
| 童年友谊经历 | 0.315 | 0.032 | 10.762a | -0.643 | 0.140 | -4.608a | 0.226 | 0.060 | 3.796a |
| 成年期社会经济地位 | | | | -0.496 | 0.081 | -6.108a | 0.273 | 0.035 | 7.832a |
| 抑郁状况 | | | | | | | -0.036 | 0.008 | -4.326a |
| 年龄 | -0.074 | 0.049 | -1.502 | -0.459 | 0.208 | -2.212b | -0.499 | 0.089 | -5.639a |
| 婚姻 | -0.017 | 0.025 | -0.676 | 0.563 | 0.106 | 5.309a | -0.037 | 0.045 | -0.824 |
| 16岁前自评健康状况 | 0.019 | 0.027 | 0.724 | -0.623 | 0.112 | -5.551a | -0.080 | 0.048 | -1.669 |
| 饮酒 | 0.297 | 0.053 | 5.568a | -0.760 | 0.226 | -3.363a | 0.085 | 0.096 | 0.877 |
| R2 | 0.056 | 0.057 | 0.061 | | | | | | |
| F | 32.141 | 27.066 | 25.105 | | | | | | |
), ArticleFig(id=1241022964829844407, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=CN, label=表3, caption=
多重中介模型回归分析结果
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 模型1:成年期社会经济地位 | 模型2:抑郁 | 模型3:认知功能 |
|---|
| β |  | t | β |  | t | β |  | t |
|---|
| 常量 | 4.172 | 0.124 | 33.630a | 12.689 | 0.623 | 20.370a | 8.417 | 0.285 | 29.535a |
| 童年友谊经历 | 0.315 | 0.032 | 10.762a | -0.643 | 0.140 | -4.608a | 0.226 | 0.060 | 3.796a |
| 成年期社会经济地位 | | | | -0.496 | 0.081 | -6.108a | 0.273 | 0.035 | 7.832a |
| 抑郁状况 | | | | | | | -0.036 | 0.008 | -4.326a |
| 年龄 | -0.074 | 0.049 | -1.502 | -0.459 | 0.208 | -2.212b | -0.499 | 0.089 | -5.639a |
| 婚姻 | -0.017 | 0.025 | -0.676 | 0.563 | 0.106 | 5.309a | -0.037 | 0.045 | -0.824 |
| 16岁前自评健康状况 | 0.019 | 0.027 | 0.724 | -0.623 | 0.112 | -5.551a | -0.080 | 0.048 | -1.669 |
| 饮酒 | 0.297 | 0.053 | 5.568a | -0.760 | 0.226 | -3.363a | 0.085 | 0.096 | 0.877 |
| R2 | 0.056 | 0.057 | 0.061 | | | | | | |
| F | 32.141 | 27.066 | 25.105 | | | | | | |
), ArticleFig(id=1241022964934702015, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=EN, label=Table 4, caption=
Chain mediation path analysis
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| 效应分类 | 效应量(95% CI) |  | 效应占比(%) |
|---|
| 总效应 | 0.351(0.235~0.466) | 0.059 | 100.00 |
| 直接效应 | 0.226(0.109~0.343) | 0.060 | 64.39 |
| 总中介效应 | 0.124(0.091~0.159) | 0.017 | 35.33 |
| 友谊经历->成年期社会经济地位->认知功能 | 0.095(0.067~0.126) | 0.015 | 27.07 |
| 友谊经历->抑郁->认知功能 | 0.023(0.009~0.040) | 0.008 | 6.55 |
| 友谊经历->成年期社会经济地位->抑郁->认知功能 | 0.006(0.003~0.010) | 0.002 | 1.71 |
), ArticleFig(id=1241022965014393794, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241022952100131083, language=CN, label=表4, caption=
链式中介路径分析
, figureFileSmall=null, figureFileBig=null, tableContent=
| 效应分类 | 效应量(95% CI) |  | 效应占比(%) |
|---|
| 总效应 | 0.351(0.235~0.466) | 0.059 | 100.00 |
| 直接效应 | 0.226(0.109~0.343) | 0.060 | 64.39 |
| 总中介效应 | 0.124(0.091~0.159) | 0.017 | 35.33 |
| 友谊经历->成年期社会经济地位->认知功能 | 0.095(0.067~0.126) | 0.015 | 27.07 |
| 友谊经历->抑郁->认知功能 | 0.023(0.009~0.040) | 0.008 | 6.55 |
| 友谊经历->成年期社会经济地位->抑郁->认知功能 | 0.006(0.003~0.010) | 0.002 | 1.71 |
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