Article(id=1240651446492910414, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1240651438955754377, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202403417, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1711036800000, receivedDateStr=2024-03-22, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773723955033, onlineDateStr=2026-03-17, pubDate=1719244800000, pubDateStr=2024-06-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773723955033, onlineIssueDateStr=2026-03-17, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773723955033, creator=13701087609, updateTime=1773723955033, updator=13701087609, issue=Issue{id=1240651438955754377, tenantId=1146029695717560320, journalId=1227665162245664772, year='2024', volume='51', issue='12', pageStart='2113', pageEnd='2912', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773723953236, creator=13701087609, updateTime=1773723953236, updator=13701087609, preIssue=null, nextIssue=null, ext=null, issueFiles=null}, startPage=2193, endPage=2197, ext={EN=ArticleExt(id=1240651448002859877, articleId=1240651446492910414, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Epidemiological characteristics of infant deaths due to perinatal diseases in China, 2012-2021, columnId=1228016568949474136, journalTitle=Modern Preventive Medicine, columnName=Child and Adolescent health, Maternal and Child Health, runingTitle=null, highlight=null, articleAbstract=
Objective To understand the epidemiological characteristics and trends of infant deaths due to perinatal diseases in China from 2012 to 2021, in order to provide a reference for the development of related prevention measures and policies.
Methods An epidemiological analysis was conducted on the data of infant deaths due to perinatal diseases from 0-year-old group in the "Chinese Cause of Death Surveillance Dataset" for the years 2012-2021. The average annual percent change (AAPC) in mortality rates was analyzed using the Joinpoint regression model.
Results The overall mortality rate of infants due to perinatal diseases in China showed a downward trend from 2012 to 2021 (AAPC=-11.89, P<0.001). A declining trend was observed in both male and female infants, as well as urban and rural infants, with AAPCs of -11.73%, -11.98%, -18.70%, and -18.50%, respectively. There was a turning point in the trend for urban infants (APC=-5.20, P=0.124 for 2012-2016 and APC=-18.70, P<0.001 for 2016-2021). The annual average mortality rate due to perinatal diseases was higher in male infants (1.79 per thousand) than in female infants (1.36 per thousand) (χ2=776.474, P<0.001), and higher in rural infants (1.55 per thousand) than in urban infants (0.46 per thousand) (χ2=75.394, P<0.001). The overall mortality rates of "low birth weight, birth trauma and asphyxia, and others" showed a downward trend (AAPCs of -14.10%, -11.10%, and -9.60%, respectively, P<0.001), with differences between urban and rural areas observed in all three perinatal diseases (P<0.001 for each).
Conclusion The mortality rate of infants due to perinatal diseases in China shows a general downward trend from 2012 to 2021, but the situation of deaths caused by perinatal diseases remains severe. The gap between urban and rural areas is significant, and priority should be given to the perinatal preventive health care of male infants and rural infants.
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目的 了解中国2012—2021年婴儿因围生期疾病死亡的流行特征及趋势,为相关预防措施和政策制定提供参考依据。
方法 对《中国死因监测数据集》中的2012—2021年 0岁组婴儿因围生期疾病死亡资料进行描述流行病学分析,采用Joinpoint回归模型分析死亡率的平均年度变化百分比(AAPC)。
结果 2012—2021年中国0岁组婴儿因围生期疾病死亡率总体呈下降趋势(AAPC=-11.89,P<0.001)。男婴、女婴、城市婴儿、农村婴儿因围生期疾病死亡率总体均呈下降趋势(AAPC分别为-11.73%、-11.98%、-18.70%、-18.50%)。男婴因围生期疾病年均死亡率(1.79‰)高于女婴(1.36‰)(χ2=776.474,P<0.001),农村婴儿因围生期疾病年均死亡率(1.55‰)高于城市婴儿(0.46‰)(χ2=75.394,P≤0.001)。“出生低体重、出生产伤和窒息、其他”是因围生期疾病的主要死因构成,2012—2021年死亡率均呈下降趋势(AAPC分别为-14.10%、-11.10%、-9.60%,P<0.001)。
结论 中国0岁组婴儿因围生期疾病死亡率2012—2021年总体呈下降趋势,但因围生期疾病导致的死亡情况依然严峻。城乡差距明显,应重点关注男婴和农村婴儿围生期预防保健工作。
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庹安写(1976—),女,硕士,副教授,研究方向:妇幼心理
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Joinpoint regression of infant mortality rate due to perinatal diseases in China, 2012-2021, figureFileSmall=Zpz37fn469WErRIM7jHitw==, figureFileBig=+gpEoqrTBcl/ShY5hriOtw==, tableContent=null), ArticleFig(id=1240651454617276722, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=CN, label=图1, caption=
2012—2021年中国婴儿因围产期疾病死亡率Joinpoint回归, figureFileSmall=Zpz37fn469WErRIM7jHitw==, figureFileBig=+gpEoqrTBcl/ShY5hriOtw==, tableContent=null), ArticleFig(id=1240651454831186245, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=EN, label=Fig.2, caption=
Joinpoint regression analysis of infant mortality rate due to perinatal diseases among urban and rural infants in China, 2012-2021, figureFileSmall=FtOGw0Fn4chQa1XEHnlX0A==, figureFileBig=NSPSD3u0pLNh7eG0/rWtXA==, tableContent=null), ArticleFig(id=1240651454944432460, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=CN, label=图2, caption=
2012—2021年中国城乡婴儿因围产期疾病死亡率Joinpoint回归, figureFileSmall=FtOGw0Fn4chQa1XEHnlX0A==, figureFileBig=NSPSD3u0pLNh7eG0/rWtXA==, tableContent=null), ArticleFig(id=1240651455070261589, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=EN, label=Table 1, caption=
Mortality rate of neonates due to perinatal conditions in China from 2012 to 2021
, figureFileSmall=null, figureFileBig=null, tableContent=
| 年份 | 总体 | 男 | 女 | 城市 | 农村 |
|---|
| 2012 | 6.44 | 6.78 | 6.04 | 5.36 | 6.72 |
| 2013 | 4.91 | 5.37 | 4.35 | 5.19 | 4.83 |
| 2014 | 4.58 | 5.10 | 3.94 | 5.23 | 4.40 |
| 2015 | 3.98 | 4.38 | 3.50 | 4.40 | 3.87 |
| 2016 | 3.67 | 4.10 | 3.16 | 4.34 | 3.50 |
| 2017 | 3.32 | 3.72 | 2.85 | 3.87 | 3.18 |
| 2018 | 2.74 | 2.98 | 2.45 | 2.99 | 2.67 |
| 2019 | 2.44 | 2.82 | 2.02 | 2.25 | 2.50 |
| 2020 | 2.05 | 2.23 | 1.86 | 1.88 | 2.11 |
| 2021 | 1.89 | 2.01 | 1.76 | 1.67 | 1.95 |
| 合计 | 1.59 | 1.79 | 1.36 | 0.46 | 1.59 |
| χ2 | - | 776.474 | 75.394 |
| P值 | - | <0.001 | <0.001 |
), ArticleFig(id=1240651455170924892, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=CN, label=表1, caption=
2012—2021年中国婴儿因围生期疾病死亡率
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| 年份 | 总体 | 男 | 女 | 城市 | 农村 |
|---|
| 2012 | 6.44 | 6.78 | 6.04 | 5.36 | 6.72 |
| 2013 | 4.91 | 5.37 | 4.35 | 5.19 | 4.83 |
| 2014 | 4.58 | 5.10 | 3.94 | 5.23 | 4.40 |
| 2015 | 3.98 | 4.38 | 3.50 | 4.40 | 3.87 |
| 2016 | 3.67 | 4.10 | 3.16 | 4.34 | 3.50 |
| 2017 | 3.32 | 3.72 | 2.85 | 3.87 | 3.18 |
| 2018 | 2.74 | 2.98 | 2.45 | 2.99 | 2.67 |
| 2019 | 2.44 | 2.82 | 2.02 | 2.25 | 2.50 |
| 2020 | 2.05 | 2.23 | 1.86 | 1.88 | 2.11 |
| 2021 | 1.89 | 2.01 | 1.76 | 1.67 | 1.95 |
| 合计 | 1.59 | 1.79 | 1.36 | 0.46 | 1.59 |
| χ2 | - | 776.474 | 75.394 |
| P值 | - | <0.001 | <0.001 |
), ArticleFig(id=1240651456731205995, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=EN, label=Table 2, caption=
Mortality rates by cause of death from perinatal diseases and their proportions in total causes of death among infants in China, 2012-2021
, figureFileSmall=null, figureFileBig=null, tableContent=
| 年份 | 死因别死亡率(/10万)及占总死因构成比(%) |
|---|
| 出生低体重 | 出生产伤和窒息 | 其他 |
|---|
| 2012 | 8.95(14.16) | 16.02(25.36) | 5.5(8.77) |
| 2013 | 7.12(14.49) | 11.95(24.30) | 3.66(7.46) |
| 2014 | 5.93(12.88) | 11.86(25.76) | 3.67(7.98) |
| 2015 | 5.04(12.60) | 10.37(25.94) | 3.38(8.45) |
| 2016 | 4.36(11.74) | 9.96(26.85) | 3.60(9.71) |
| 2017 | 3.90(11.61) | 8.94(26.65) | 3.14(9.35) |
| 2018 | 3.26(11.84) | 7.12(25.87) | 2.69(9.79) |
| 2019 | 2.68(11.12) | 6.21(25.79) | 2.45(10.18) |
| 2020 | 2.67(13.17) | 5.52(27.26) | 1.99(9.82) |
| 2021 | 2.12(11.39) | 5.12(27.57) | 1.70(9.13) |
| 合计 | 4.21(12.53) | 8.74(26.00) | 3.00(8.90) |
), ArticleFig(id=1240651456852840817, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=CN, label=表2, caption=
2012—2021年中国婴儿因围生期疾病死因别死亡率及占总死因构成比
, figureFileSmall=null, figureFileBig=null, tableContent=
| 年份 | 死因别死亡率(/10万)及占总死因构成比(%) |
|---|
| 出生低体重 | 出生产伤和窒息 | 其他 |
|---|
| 2012 | 8.95(14.16) | 16.02(25.36) | 5.5(8.77) |
| 2013 | 7.12(14.49) | 11.95(24.30) | 3.66(7.46) |
| 2014 | 5.93(12.88) | 11.86(25.76) | 3.67(7.98) |
| 2015 | 5.04(12.60) | 10.37(25.94) | 3.38(8.45) |
| 2016 | 4.36(11.74) | 9.96(26.85) | 3.60(9.71) |
| 2017 | 3.90(11.61) | 8.94(26.65) | 3.14(9.35) |
| 2018 | 3.26(11.84) | 7.12(25.87) | 2.69(9.79) |
| 2019 | 2.68(11.12) | 6.21(25.79) | 2.45(10.18) |
| 2020 | 2.67(13.17) | 5.52(27.26) | 1.99(9.82) |
| 2021 | 2.12(11.39) | 5.12(27.57) | 1.70(9.13) |
| 合计 | 4.21(12.53) | 8.74(26.00) | 3.00(8.90) |
), ArticleFig(id=1240651456995447164, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=EN, label=Table 3, caption=
Mortality rates and differences by cause of perinatal disease deaths among urban and rural infants in China, 2012—2021
, figureFileSmall=null, figureFileBig=null, tableContent=
| 年份 | 城乡婴儿因围生期疾病死因别死亡率(/10万) |
|---|
| 出生低体重 | 出生产伤和窒息 | 其他 |
|---|
| 城市 | 农村 | 城市 | 农村 | 城市 | 农村 |
|---|
| 2012 | 9.82 | 8.59 | 13.96 | 16.89 | 3.89 | 6.23 |
| 2013 | 7.53 | 6.99 | 14.10 | 11.27 | 3.87 | 3.61 |
| 2014 | 6.84 | 5.63 | 13.93 | 11.19 | 4.91 | 3.28 |
| 2015 | 5.00 | 5.05 | 12.15 | 9.81 | 3.67 | 3.29 |
| 2016 | 5.59 | 3.94 | 12.56 | 9.09 | 4.37 | 3.35 |
| 2017 | 4.45 | 3.71 | 10.67 | 8.31 | 3.99 | 2.85 |
| 2018 | 3.87 | 3.04 | 8.30 | 6.70 | 2.98 | 2.59 |
| 2019 | 2.49 | 2.79 | 6.10 | 6.32 | 2.19 | 2.59 |
| 2020 | 2.86 | 2.57 | 5.08 | 5.78 | 1.99 | 2.00 |
| 2021 | 2.02 | 2.16 | 4.93 | 5.24 | 1.79 | 1.67 |
| 合计 | 4.44 | 4.12 | 9.42 | 8.49 | 4.04 | 2.93 |
| χ2 | 12.567 | 51.470 | 12.726 |
| P值 | <0.001 | <0.001 | <0.001 |
), ArticleFig(id=1240651457104499078, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240651446492910414, language=CN, label=表3, caption=
2012—2021年中国城市、农村婴儿因围生期疾病的死因别死亡率及差异
, figureFileSmall=null, figureFileBig=null, tableContent=
| 年份 | 城乡婴儿因围生期疾病死因别死亡率(/10万) |
|---|
| 出生低体重 | 出生产伤和窒息 | 其他 |
|---|
| 城市 | 农村 | 城市 | 农村 | 城市 | 农村 |
|---|
| 2012 | 9.82 | 8.59 | 13.96 | 16.89 | 3.89 | 6.23 |
| 2013 | 7.53 | 6.99 | 14.10 | 11.27 | 3.87 | 3.61 |
| 2014 | 6.84 | 5.63 | 13.93 | 11.19 | 4.91 | 3.28 |
| 2015 | 5.00 | 5.05 | 12.15 | 9.81 | 3.67 | 3.29 |
| 2016 | 5.59 | 3.94 | 12.56 | 9.09 | 4.37 | 3.35 |
| 2017 | 4.45 | 3.71 | 10.67 | 8.31 | 3.99 | 2.85 |
| 2018 | 3.87 | 3.04 | 8.30 | 6.70 | 2.98 | 2.59 |
| 2019 | 2.49 | 2.79 | 6.10 | 6.32 | 2.19 | 2.59 |
| 2020 | 2.86 | 2.57 | 5.08 | 5.78 | 1.99 | 2.00 |
| 2021 | 2.02 | 2.16 | 4.93 | 5.24 | 1.79 | 1.67 |
| 合计 | 4.44 | 4.12 | 9.42 | 8.49 | 4.04 | 2.93 |
| χ2 | 12.567 | 51.470 | 12.726 |
| P值 | <0.001 | <0.001 | <0.001 |
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