Article(id=1240395011687248800, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1240395006914130733, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202412177, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1733846400000, receivedDateStr=2024-12-11, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773662816210, onlineDateStr=2026-03-16, pubDate=1753372800000, pubDateStr=2025-07-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773662816210, onlineIssueDateStr=2026-03-16, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773662816210, creator=13701087609, updateTime=1773662816210, updator=13701087609, issue=Issue{id=1240395006914130733, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='14', pageStart='2497', pageEnd='2688', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1773662815073, creator=13701087609, updateTime=1773662858015, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1240395187109810535, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1240395006914130733, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1240395187109810536, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1240395006914130733, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=2601, endPage=2606, ext={EN=ArticleExt(id=1240395011917935541, articleId=1240395011687248800, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Study on the composition and influencing factors of hospitalization expenses of rare disease patients under different medical levels, Jiangxi, columnId=1228016567846367388, journalTitle=Modern Preventive Medicine, columnName=Health Policy and Management, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the internal structure and influencing factors of hospitalization expenses for rare disease patients at different medical levels in Jiangxi Province’s “Health Expenditure Accounting System 2011” (SHA2011) sentinel hospitals, providing references for rare disease treatment in Jiangxi Province and its healthcare institutions.
Methods Data on rare disease patients from 2018 to 2022 were collected from the sample hospitals in Jiangxi Province. Structural variation analysis and grey correlation analysis were employed to examine changes in the internal composition of hospitalization expenses and their interrelationships, while a random forest model was used to identify factors influencing the average total cost per hospitalization case.
Results From 2018 to 2022, the average hospitalization costs per case were 19 082.70 yuan (provincial), 8 175.29 yuan (municipal), and 6 586.23 yuan (county/district). The random forest model revealed that medication fees and diagnostic examination fees were key factors affecting rare disease hospitalization costs, with structural variation values of -3.15, -1.79, and 5.30 for medication fees, and -3.86, 5.48, and 2.16 for diagnostic examination fees at provincial, municipal, and county/district levels, respectively. Grey correlation analysis showed that surgical fees and nursing fees had low correlation degrees with hospitalization costs across all levels, ranking between 7th and 8th.
Conclusion From 2018 to 2022, hospitalization expenses at all levels exhibit fluctuating trends but remained generally high. Medication fees and diagnostic examination fees are critical influencing factors, though their structural variation trends and contribution rates differed significantly across hospital tiers. Additionally, surgical and nursing fees demonstrate consistently low correlation with hospitalization costs at all levels.
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目的 分析江西省《卫生费用核算体系2011》(SHA2011)检测点医院的罕见病患者住院费用在不同医疗层级的内部结构和影响因素,为江西省以及各医院治疗罕见病提供参考。
方法 收集2018—2022年江西省样本医院有关罕见病患者相关数据,运用结构变动度分析法和灰色关联分析法,研究住院费用内部构成结构变化以及相互间关联程度,运用随机森林模型分析住院患者例均总费用的影响因素。
结果 2018—2022年,省、市、县(区)级医院组例均住院费用分别为19 082.70、8 175.29和6 586.23;由随机森林模型结果显示,药品费和检查诊查费是影响罕见病住院费用的重要因素,省、市、县(区)级药品费结构变动值分别为-3.15、-1.79和5.30,检查诊查费结构变动值分别为-3.86、5.48和2.16;灰色关联分析结果显示,手术费、护理费在省、市、县(区)级医院对罕见病住院费用的关联程度均排名在7和8之间。
结论 2018—2022年,各层级医院住院费用整体呈上下波动趋势但总体住院费用偏高;药品费和检查诊查费是影响罕见病住院费用的关键因素,但在各层级医院的结构变动趋势和结构贡献率存在显著差异;同时,手术费、护理费与住院费用的关联度在各层级医院普遍偏低。
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=4nJNf+JHJ2TeZi6IGXHVfw==, magXml=8qLKPICW/yJklNB8WI3sCg==, pdfUrl=null, pdf=v2h8sFYQUfgQzAwym8c9qQ==, pdfFileSize=957194, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=u+Rno4xEUIfa83jSrV3cWA==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=66e6sDSJJBrdkL3Ag0jYpA==, mapNumber=null, authorCompany=null, fund=null, authors=
刘慧玲(1999—),女,硕士在读,研究方向:罕见病研究
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1, 3, address=School of Economics and Management, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330004, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1240413546710880577, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, authorId=1240413546480193838, language=CN, stringName=赵恒伯, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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3.豫章师范学院书记办公室)])], figs=[ArticleFig(id=1240413549768528277, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=EN, label=Fig.1, caption=
Trend inaverage total cost per case for hospitalized patients with rare diseases in Jiangxi Province,2018—2022, figureFileSmall=UmW/qqEOkM5kHEc9lxfNrw==, figureFileBig=kMaTbvshZow17QpE9uJfGw==, tableContent=null), ArticleFig(id=1240413549923717530, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=CN, label=图1, caption=
2018—2022年江西省罕见病住院患者例均总费用变化情况, figureFileSmall=UmW/qqEOkM5kHEc9lxfNrw==, figureFileBig=kMaTbvshZow17QpE9uJfGw==, tableContent=null), ArticleFig(id=1240413550011797919, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=EN, label=Fig.2, caption=
Contribution rate of structural change in hospitalization costs for rare diseases in Jiangxi Province,2018—2022, figureFileSmall=s9nox/twgPP3cvQpOtukMQ==, figureFileBig=d2kUB4da5GDQmNHWq9IcBQ==, tableContent=null), ArticleFig(id=1240413550125044134, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=CN, label=图2, caption=
2018—2022年江西省罕见病患者住院费用结构变动贡献率, figureFileSmall=s9nox/twgPP3cvQpOtukMQ==, figureFileBig=d2kUB4da5GDQmNHWq9IcBQ==, tableContent=null), ArticleFig(id=1240413550200541611, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=EN, label=Fig.3, caption=
Importance ranking of influencing factors for hospitalization costs of patients with rare diseases in Jiangxi Province, figureFileSmall=f6caNLQnTsVi2Kbr53czmA==, figureFileBig=wP9E+Deq3abttqBJJ17cXg==, tableContent=null), ArticleFig(id=1240413550284427697, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=CN, label=图3, caption=
江西省罕见病患者住院费用影响因素重要性排序, figureFileSmall=f6caNLQnTsVi2Kbr53czmA==, figureFileBig=wP9E+Deq3abttqBJJ17cXg==, tableContent=null), ArticleFig(id=1240413550393479607, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=EN, label=Table 1, caption=
Variable assignments in the Random Forest Model
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 赋值说明 |
|---|
| 医院类别 | 1=综合医院,2=中医院,3=专科医院,4=妇幼保健机构 |
| 付费方式 | 1=城镇职工,2=城乡居民,3=全自费,4=其它 |
| 疾病类型 | 1=肿瘤,2=血液及造血器官疾病和某些免疫机制的疾患,3=内分泌、营养和代谢疾病,4=精神和行为障碍,5=眼和附器疾病,6=耳和乳突疾病,7=循环系统疾病,8=呼吸系统疾病9=消化系统疾病,10=肌肉骨骼系统和结缔组织疾病,11=先天性畸形,变色和染色体异常,12=神经系统疾病,13=泌尿生殖系统疾病,14=皮肤和皮下组织疾病,15=起源于围生期的某些状况,16=妊娠、分娩和产褥期 |
| 实际住院天数 | 实际值 |
| 药占比(%) | 实际值 |
| 手术治疗费用占比(%) | 实际值 |
| 检查化验费用占比(%) | 实际值 |
| 例均总费用(元) | 例均总费用取自然对数 |
), ArticleFig(id=1240413550523503038, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=CN, label=表1, caption=
随机森林模型变量赋值
, figureFileSmall=null, figureFileBig=null, tableContent=
| 变量 | 赋值说明 |
|---|
| 医院类别 | 1=综合医院,2=中医院,3=专科医院,4=妇幼保健机构 |
| 付费方式 | 1=城镇职工,2=城乡居民,3=全自费,4=其它 |
| 疾病类型 | 1=肿瘤,2=血液及造血器官疾病和某些免疫机制的疾患,3=内分泌、营养和代谢疾病,4=精神和行为障碍,5=眼和附器疾病,6=耳和乳突疾病,7=循环系统疾病,8=呼吸系统疾病9=消化系统疾病,10=肌肉骨骼系统和结缔组织疾病,11=先天性畸形,变色和染色体异常,12=神经系统疾病,13=泌尿生殖系统疾病,14=皮肤和皮下组织疾病,15=起源于围生期的某些状况,16=妊娠、分娩和产褥期 |
| 实际住院天数 | 实际值 |
| 药占比(%) | 实际值 |
| 手术治疗费用占比(%) | 实际值 |
| 检查化验费用占比(%) | 实际值 |
| 例均总费用(元) | 例均总费用取自然对数 |
), ArticleFig(id=1240413550628360644, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=EN, label=Table 2, caption=
Structural change values and degree of change in hospitalization costs for rare diseases in Jiangxi Province,2018—2022
, figureFileSmall=null, figureFileBig=null, tableContent=
| 类别 | 时间(年份) | VSV结构变动值 | DSV结构变动度(%) |
|---|
| 治疗费 | 药品费 | 床位费 | 检查诊查费 | 手术费 | 化验费 | 护理费 | 其他费用 |
|---|
| 省级医院组 | 2018—2019年 | 0.04 | 1.87 | 0.08 | 0.00 | -0.46 | -0.74 | -2.00 | 1.21 | 6.41 |
| 2019—2020年 | 9.02 | 1.12 | -1.21 | -2.22 | 0.27 | -2.18 | -1.59 | -3.20 | 20.81 |
| 2020—2021年 | -9.62 | -1.30 | 1.32 | 2.92 | -0.13 | 3.76 | 0.51 | 2.53 | 22.09 |
| 2021—2022年 | 21.40 | -4.84 | -0.83 | -4.55 | -0.43 | -6.43 | -0.54 | -3.78 | 42.80 |
| 2018—2022年 | 20.84 | -3.15 | -0.63 | -3.86 | -0.76 | -5.59 | -3.62 | -3.23 | 41.68 |
| 市级医院组 | 2018—2019年 | 1.15 | 1.22 | 1.41 | 0.83 | -2.14 | -0.12 | -5.11 | 2.78 | 14.76 |
| 2019—2020年 | -11.67 | 13.69 | -1.94 | 1.63 | 0.41 | 5.77 | -3.82 | -4.07 | 42.99 |
| 2020—2021年 | 10.26 | -16.95 | 0.27 | 3.66 | 5.21 | -3.04 | 0.05 | 0.55 | 39.99 |
| 2021—2022年 | 1.37 | 0.30 | 1.27 | -0.64 | -3.74 | -2.02 | 0.71 | 2.74 | 12.79 |
| 2018—2022年 | 1.11 | -1.74 | 1.01 | 5.48 | -0.26 | 0.58 | -8.18 | 1.99 | 20.35 |
| 县(区)级医院组 | 2018—2019年 | 11.68 | -1.79 | -0.99 | 3.10 | -0.72 | 0.17 | -6.35 | -5.10 | 29.91 |
| 2019—2020年 | -19.27 | 16.92 | -1.01 | -3.53 | -0.43 | -0.98 | -0.18 | 8.47 | 50.79 |
| 2020—2021年 | 6.17 | -1.28 | 0.17 | 3.06 | 0.13 | -0.58 | -0.80 | -6.86 | 19.04 |
| 2021—2022年 | -0.48 | -8.54 | 1.37 | -0.46 | -0.22 | 4.12 | 1.94 | 2.28 | 19.41 |
| 2018—2022年 | -1.89 | 5.30 | -0.47 | 2.16 | -1.24 | 2.73 | -5.39 | -1.20 | 20.38 |
), ArticleFig(id=1240413550749995467, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=CN, label=表2, caption=
2018—2022年江西省罕见病住院费用结构变动值及结构变动度
, figureFileSmall=null, figureFileBig=null, tableContent=
| 类别 | 时间(年份) | VSV结构变动值 | DSV结构变动度(%) |
|---|
| 治疗费 | 药品费 | 床位费 | 检查诊查费 | 手术费 | 化验费 | 护理费 | 其他费用 |
|---|
| 省级医院组 | 2018—2019年 | 0.04 | 1.87 | 0.08 | 0.00 | -0.46 | -0.74 | -2.00 | 1.21 | 6.41 |
| 2019—2020年 | 9.02 | 1.12 | -1.21 | -2.22 | 0.27 | -2.18 | -1.59 | -3.20 | 20.81 |
| 2020—2021年 | -9.62 | -1.30 | 1.32 | 2.92 | -0.13 | 3.76 | 0.51 | 2.53 | 22.09 |
| 2021—2022年 | 21.40 | -4.84 | -0.83 | -4.55 | -0.43 | -6.43 | -0.54 | -3.78 | 42.80 |
| 2018—2022年 | 20.84 | -3.15 | -0.63 | -3.86 | -0.76 | -5.59 | -3.62 | -3.23 | 41.68 |
| 市级医院组 | 2018—2019年 | 1.15 | 1.22 | 1.41 | 0.83 | -2.14 | -0.12 | -5.11 | 2.78 | 14.76 |
| 2019—2020年 | -11.67 | 13.69 | -1.94 | 1.63 | 0.41 | 5.77 | -3.82 | -4.07 | 42.99 |
| 2020—2021年 | 10.26 | -16.95 | 0.27 | 3.66 | 5.21 | -3.04 | 0.05 | 0.55 | 39.99 |
| 2021—2022年 | 1.37 | 0.30 | 1.27 | -0.64 | -3.74 | -2.02 | 0.71 | 2.74 | 12.79 |
| 2018—2022年 | 1.11 | -1.74 | 1.01 | 5.48 | -0.26 | 0.58 | -8.18 | 1.99 | 20.35 |
| 县(区)级医院组 | 2018—2019年 | 11.68 | -1.79 | -0.99 | 3.10 | -0.72 | 0.17 | -6.35 | -5.10 | 29.91 |
| 2019—2020年 | -19.27 | 16.92 | -1.01 | -3.53 | -0.43 | -0.98 | -0.18 | 8.47 | 50.79 |
| 2020—2021年 | 6.17 | -1.28 | 0.17 | 3.06 | 0.13 | -0.58 | -0.80 | -6.86 | 19.04 |
| 2021—2022年 | -0.48 | -8.54 | 1.37 | -0.46 | -0.22 | 4.12 | 1.94 | 2.28 | 19.41 |
| 2018—2022年 | -1.89 | 5.30 | -0.47 | 2.16 | -1.24 | 2.73 | -5.39 | -1.20 | 20.38 |
), ArticleFig(id=1240413550871630287, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=EN, label=Table 3, caption=
New Grey Relational Indicators for per-admission hospitalization costs of patients with rare diseases in sample hospitals, 2018-2022
, figureFileSmall=null, figureFileBig=null, tableContent=
| 类别 | 年份 | 治疗费 | 药品费 | 床位费 | 检查诊查费 | 手术费 | 化验费 | 护理费 | 其他费用 |
|---|
| 省级医院组 | 2018年 | 0.13 | 1.02 | 0.27 | 0.28 | 0.18 | 0.25 | 0.06 | 0.37 |
| 2019年 | 0.12 | 1.00 | 0.30 | 0.38 | 0.36 | 0.52 | 0.29 | 0.25 |
| 2020年 | 0.27 | 0.83 | 0.12 | 0.26 | 0.46 | 0.29 | 0.11 | 0.25 |
| 2021年 | 0.13 | 0.56 | 0.19 | 0.20 | 0.58 | 0.18 | 0.22 | 0.26 |
| 2022年 | 0.05 | 0.48 | 0.30 | 0.15 | 0.17 | 0.14 | 0.11 | 0.18 |
| 关联度 | 0.14 | 0.78 | 0.24 | 0.26 | 0.35 | 0.27 | 0.16 | 0.26 |
| 关联序 | 8 | 1 | 6 | 5 | 2 | 3 | 7 | 4 |
| 市级医院组 | 2018年 | 0.58 | 0.90 | 0.44 | 0.29 | 0.20 | 0.67 | 0.10 | 0.63 |
| 2019年 | 0.08 | 0.11 | 0.07 | 0.17 | 0.09 | 0.13 | 0.09 | 0.08 |
| 2020年 | 0.12 | 0.76 | 0.15 | 0.24 | 0.10 | 0.61 | 0.13 | 0.16 |
| 2021年 | 0.29 | 0.22 | 0.18 | 1.00 | 0.06 | 0.33 | 0.14 | 0.20 |
| 2022年 | 0.45 | 0.24 | 0.48 | 0.71 | 0.63 | 0.27 | 0.15 | 0.41 |
| 关联度 | 0.30 | 0.44 | 0.26 | 0.48 | 0.22 | 0.41 | 0.12 | 0.30 |
| 关联序 | 4 | 2 | 6 | 1 | 7 | 3 | 8 | 5 |
| 县(区)级医院组 | 2018年 | 0.96 | 0.41 | 0.25 | 0.27 | 0.07 | 0.96 | 0.10 | 0.72 |
| 2019年 | 0.08 | 0.32 | 1.00 | 0.39 | 0.59 | 0.79 | 0.29 | 0.24 |
| 2020年 | 0.10 | 0.78 | 0.21 | 0.20 | 0.15 | 0.42 | 0.24 | 0.31 |
| 2021年 | 0.82 | 0.19 | 0.91 | 0.18 | 0.65 | 0.53 | 0.35 | 0.77 |
| 2022年 | 0.28 | 0.63 | 0.45 | 0.90 | 0.13 | 0.46 | 0.63 | 0.91 |
| 关联度 | 0.45 | 0.47 | 0.56 | 0.39 | 0.32 | 0.63 | 0.32 | 0.59 |
| 关联序 | 5 | 4 | 3 | 6 | 8 | 1 | 7 | 2 |
), ArticleFig(id=1240413551005848020, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1240395011687248800, language=CN, label=表3, caption=
2018—2022年样本医院罕见病患者次均住院费用新灰色关联指标
, figureFileSmall=null, figureFileBig=null, tableContent=
| 类别 | 年份 | 治疗费 | 药品费 | 床位费 | 检查诊查费 | 手术费 | 化验费 | 护理费 | 其他费用 |
|---|
| 省级医院组 | 2018年 | 0.13 | 1.02 | 0.27 | 0.28 | 0.18 | 0.25 | 0.06 | 0.37 |
| 2019年 | 0.12 | 1.00 | 0.30 | 0.38 | 0.36 | 0.52 | 0.29 | 0.25 |
| 2020年 | 0.27 | 0.83 | 0.12 | 0.26 | 0.46 | 0.29 | 0.11 | 0.25 |
| 2021年 | 0.13 | 0.56 | 0.19 | 0.20 | 0.58 | 0.18 | 0.22 | 0.26 |
| 2022年 | 0.05 | 0.48 | 0.30 | 0.15 | 0.17 | 0.14 | 0.11 | 0.18 |
| 关联度 | 0.14 | 0.78 | 0.24 | 0.26 | 0.35 | 0.27 | 0.16 | 0.26 |
| 关联序 | 8 | 1 | 6 | 5 | 2 | 3 | 7 | 4 |
| 市级医院组 | 2018年 | 0.58 | 0.90 | 0.44 | 0.29 | 0.20 | 0.67 | 0.10 | 0.63 |
| 2019年 | 0.08 | 0.11 | 0.07 | 0.17 | 0.09 | 0.13 | 0.09 | 0.08 |
| 2020年 | 0.12 | 0.76 | 0.15 | 0.24 | 0.10 | 0.61 | 0.13 | 0.16 |
| 2021年 | 0.29 | 0.22 | 0.18 | 1.00 | 0.06 | 0.33 | 0.14 | 0.20 |
| 2022年 | 0.45 | 0.24 | 0.48 | 0.71 | 0.63 | 0.27 | 0.15 | 0.41 |
| 关联度 | 0.30 | 0.44 | 0.26 | 0.48 | 0.22 | 0.41 | 0.12 | 0.30 |
| 关联序 | 4 | 2 | 6 | 1 | 7 | 3 | 8 | 5 |
| 县(区)级医院组 | 2018年 | 0.96 | 0.41 | 0.25 | 0.27 | 0.07 | 0.96 | 0.10 | 0.72 |
| 2019年 | 0.08 | 0.32 | 1.00 | 0.39 | 0.59 | 0.79 | 0.29 | 0.24 |
| 2020年 | 0.10 | 0.78 | 0.21 | 0.20 | 0.15 | 0.42 | 0.24 | 0.31 |
| 2021年 | 0.82 | 0.19 | 0.91 | 0.18 | 0.65 | 0.53 | 0.35 | 0.77 |
| 2022年 | 0.28 | 0.63 | 0.45 | 0.90 | 0.13 | 0.46 | 0.63 | 0.91 |
| 关联度 | 0.45 | 0.47 | 0.56 | 0.39 | 0.32 | 0.63 | 0.32 | 0.59 |
| 关联序 | 5 | 4 | 3 | 6 | 8 | 1 | 7 | 2 |
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