Article(id=1324050739647098908, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324050669933572771, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202512022, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1764604800000, receivedDateStr=2025-12-02, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793607896004, onlineDateStr=2026-11-02, pubDate=1778342400000, pubDateStr=2026-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793607896004, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793607896004, creator=13701087609, updateTime=1793607896004, updator=13701087609, issue=Issue{id=1324050669933572771, tenantId=1146029695717560320, journalId=1227665162245664772, year='2026', volume='53', issue='9', pageStart='1537', pageEnd='1728', issueExtLink='null', onlineDate='null', pubDate='1778342400000', pubDateStr='2026-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793607879384, creator='13701087609', updateTime=1793670100562, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1324311644528050975, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324050669933572771, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1324311644528050976, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1324050669933572771, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1549, endPage=1556, ext={EN=ArticleExt(id=1324050739890368541, articleId=1324050739647098908, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Burden trend of spinal cord injuries due to falls in China from 1990 to 2021, columnId=1240413921954295836, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods, runingTitle=null, highlight=null, articleAbstract=
Objective This study systematically analyzed temporal trends in the burden of spinal cord injury (SCI) attributable to falls in China from 1990 to 2021, focusing on incidence, prevalence, and years lived with disability (YLD).
Methods Data were obtained from the Global Burden of Disease (GBD) 2021 database, using publicly available national estimates of fall-related SCI in China from 1990 to 2021. Descriptive analyses were conducted to characterize changes in incidence, prevalence, and YLD. Temporal trends were further examined using Joinpoint regression and age-period-cohort (APC) models.
Results In 2021, the number of prevalent cases of fall-related SCI in China was estimated at 1 480 074, with 62 724 incident cases. The age-standardized prevalence rate (ASPR) was 80.21 per 100 000 population and the age-standardized incidence rate (ASIR) was 3.76 per 100 000 population. Total YLDs reached 397 472 years, corresponding to an age-standardized YLD rate (ASYR) of 21.74 per 100 000 population. Sex-based analysis showed a substantially higher disease burden in males than in females. Joinpoint regression indicated a modest increase in ASIR during 1995—2000 (APC=1.89), a marked decline during 2000—2005 (APC=-6.12), followed by a rapid increase during 2010—2021 (2010—2015: APC=5.90; 2015—2021: APC=4.59). Similarly, ASPR showed a slight increase during 1990—2001 (APC=0.55), a significant decline during 2001—2005 (APC=-8.58), and a renewed rapid increase during 2010—2021 (APC=5.08). YLDs remained relatively stable from 1990 to 2000, declined during 2000—2007 (APC=-9.94), and increased during 2010—2021 (APC=4.68). Overall trends were comparable between males and females. APC analysis revealed a pronounced increase in SCI risk with advancing age, while period and cohort effects fluctuated but showed an overall upward pattern, suggesting that economic development, improvements in healthcare, and population aging may jointly contribute to the increasing burden.
Conclusion From 1990 to 2021, the disease burden of SCI in China has increased substantially, with males and older adults experiencing markedly higher risks than females and younger populations. Targeted public health strategies addressing population aging and risk management among high-risk groups are urgently needed to mitigate the long-term health and societal impacts of SCI.
, authors=Jie-hui LI
1, Zhi-fei LI
2, bin HAN
1, Jun-hua LI
1, Xiang-xuan ZENG
1, Jia-hao LIANG
1, jin-tao FANG
1, Yi-sheng ZHANG
2, authorsList=Jie-hui LI, Zhi-fei LI, bin HAN, Jun-hua LI, Xiang-xuan ZENG, Jia-hao LIANG, jin-tao FANG, Yi-sheng ZHANG, authorCompany=null, correspAuthors=Yi-sheng ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1324050740880224294, articleId=1324050739647098908, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=1990—2021年中国因跌倒导致的脊髓损伤的负担趋势分析, columnId=1228016567632462653, journalTitle=现代预防医学, columnName=流行病与统计方法, runingTitle=null, highlight=null, articleAbstract=
目的 本研究系统分析了1990—2021年中国因跌倒导致的脊髓损伤负担变化趋势,具体包括发病率、患病率及伤残生命年(years lived with disability,YLD)。
方法 研究基于全球疾病负担2021数据库,使用1990—2021年中国因跌倒导致的脊髓损伤相关开放数据,评估发病率、患病率和YLD的变化特征,同时应用joinpoint回归分析和年龄-时期-队列(age-period-cohort,APC)模型分析探讨时间趋势。
结果 2021年中国因跌倒导致的脊髓损伤患病人数为1 480 074例,发病人数为62 724例,年龄标准化患病率(age-standardized prevalence rate,ASPR)为80.21/10万,年龄标准化发病率(age-standardized incidence rate,ASIR)为3.76/10万,伤残生命年总数为397 472年,相应的年龄标准化伤残生命年为21.74/10万。性别差异分析显示,男性的疾病负担远高于女性。Joinpoint回归结果表明,ASIR在1995—2000年呈缓慢上升趋势(APC=1.89),2000—2005年出现显著下降(APC=-6.12),而在2010—2021年迅速上升(2010—2015年APC=5.90;2015—2021年APC=4.59)。相应地,ASPR在1990—2001年略有上升(APC=0.55),2001—2005年显著下降(APC=-8.58),并在2010—2021年再次快速增长(APC=5.08)。在YLD方面,1990—2000年保持稳定,2000—2007年下降(APC = -9.94),在2010—2021年上升(APC = 4.68),男性与女性总体趋势一致。APC模型分析结果提示,脊髓损伤发病风险随年龄增长显著上升,时期效应与队列效应虽存在波动但总体呈上升趋势,表明经济发展、医疗改善及人口老龄化可能共同推动了疾病负担的增加。
结论 1990—2019年中国因跌倒导致的脊髓损伤的疾病负担持续上升,其中男性和老年人群的发病风险显著高于女性和年轻人。相关公共卫生政策需积极应对人口老龄化及高危人群风险管理等挑战,以有效遏制脊髓损伤带来的长期健康与社会影响。
, authors=李杰辉
1, 李智斐
2, 韩斌
1, 李俊华
1, 曾祥轩
1, 梁家豪
1, 方锦涛
1, 张翼升
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李杰辉(2001—),男,硕士在读,研究方向:脊柱相关疾病的中医诊治研究
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=ZkGHT+n5OwZcp1zXUy2PZQ==, magXml=6CFbhyNOF/yCMxH+fAWYCQ==, pdfUrl=null, pdf=wsxC4QiylC2yHnt7Fb8aPQ==, pdfFileSize=1575129, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=rN5liyc+xHdCBIfAJKrDsw==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=C7P4QgZWFAS90zH9vhi2EQ==, mapNumber=null, fund=null)}, authors=[Author(id=1324050741333209133, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1324050741412900911, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, authorId=1324050741333209133, language=EN, stringName=Jie-hui LI, firstName=Jie-hui, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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Gender differences in the burden of SCI caused by falls among different age groups in China, figureFileSmall=YjAUFL281V/e95UbvIs5Xw==, figureFileBig=rN5liyc+xHdCBIfAJKrDsw==, tableContent=null), ArticleFig(id=1324050749738594398, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=CN, label=图1, caption=
中国不同年龄组因跌倒导致的脊髓损伤负担的性别差异, figureFileSmall=YjAUFL281V/e95UbvIs5Xw==, figureFileBig=rN5liyc+xHdCBIfAJKrDsw==, tableContent=null), ArticleFig(id=1324050750011224159, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=EN, label=Figure 2, caption=
Gender trends in the number of cases, ASIR, ASPR, and ASYR of SCI caused by falls in China from 1990 to 2021, figureFileSmall=Ouk2Buu65rJgilAKl+0YPg==, figureFileBig=g3DmyZM1vlrhyT9/EmNvSw==, tableContent=null), ArticleFig(id=1324050750082527328, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=CN, label=图2, caption=
1990—2021年中国因跌倒导致的脊髓损伤的病例数和ASIR、ASPR和ASYR的性别趋势, figureFileSmall=Ouk2Buu65rJgilAKl+0YPg==, figureFileBig=g3DmyZM1vlrhyT9/EmNvSw==, tableContent=null), ArticleFig(id=1324050750158024801, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=EN, label=Figure 3, caption=
Results of Joinpoint regression analysis of ASPR, ASIR, and ASYR of SCI caused by falls in China from 1990 to 2019, figureFileSmall=HtmoqhKajBiAJGeaIe7Cpw==, figureFileBig=BoS6rkPsCUhn5x2/pmx+yQ==, tableContent=null), ArticleFig(id=1324050750216745058, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=CN, label=图3, caption=
中国1990—2019年因跌倒导致的脊髓损伤ASPR、ASIR和ASYR的连接点回归分析结果注:A、B、C为ASPR的joinpoint回归分析图;D、E、F为ASIR的joinpoint回归分析图;G、H、I为ASYR的joinpoint回归分析图。
, figureFileSmall=HtmoqhKajBiAJGeaIe7Cpw==, figureFileBig=BoS6rkPsCUhn5x2/pmx+yQ==, tableContent=null), ArticleFig(id=1324050750397100131, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=EN, label=Figure 4, caption=
Age-period-cohort (APC) model of SCI caused by falls in China, figureFileSmall=kEcK1sRUTwNIFvaMhbycuA==, figureFileBig=UHxA0rOiEPBrFUhEVLLDRg==, tableContent=null), ArticleFig(id=1324050750522929252, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=CN, label=图4, caption=
中国因跌倒导致的脊髓损伤APC模型注:A为年龄曲线图展现了年龄效应;B为时期风险比图展现了时期效应;C为队列风险比图展现出生队列效应;D为净漂移和局部漂移图,进一步展现年龄效应。
, figureFileSmall=kEcK1sRUTwNIFvaMhbycuA==, figureFileBig=UHxA0rOiEPBrFUhEVLLDRg==, tableContent=null), ArticleFig(id=1324050750782976101, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=EN, label=Table 1, caption=
All age cases of SCI caused by falls in China in 2021, along with ASPR, ASIR, and YLD
, figureFileSmall=null, figureFileBig=null, tableContent=
| 测量指标 | 人数 | 年龄标准化率(/10万) |
|---|
| 两性 | 男性 | 女性 | 两性 | 男性 | 女性 |
|---|
| ASPR | 1480 074 (1 279 782~1 716 100) | 917 057 (796 955~1 054 336) | 563 017 (480 709~660 652) | 80.21 (69.21~92.94) | 99.14 (85.83~114.47) | 60.09 (51.17~71.26) |
| ASIR | 62 724 (38 326~99 430) | 38 067 (24 512~59 054) | 24 657 (13 646~41 534) | 3.76 (2.35~5.94) | 4.68 (3.05~7.14) | 2.79 (1.56~4.69) |
| YLD | 397 472 (279 486~536 646) | 252 626 (177 456~338 707) | 144 846 (100 167~195 581) | 21.74 (15.1~29.54) | 27.53 (19.09~37.48) | 15.62 (10.75~21.37) |
), ArticleFig(id=1324050751147880550, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=CN, label=表1, caption=
2021年中国因跌倒导致的脊髓损伤的所有年龄病例和ASPR、ASIR和YLD
, figureFileSmall=null, figureFileBig=null, tableContent=
| 测量指标 | 人数 | 年龄标准化率(/10万) |
|---|
| 两性 | 男性 | 女性 | 两性 | 男性 | 女性 |
|---|
| ASPR | 1480 074 (1 279 782~1 716 100) | 917 057 (796 955~1 054 336) | 563 017 (480 709~660 652) | 80.21 (69.21~92.94) | 99.14 (85.83~114.47) | 60.09 (51.17~71.26) |
| ASIR | 62 724 (38 326~99 430) | 38 067 (24 512~59 054) | 24 657 (13 646~41 534) | 3.76 (2.35~5.94) | 4.68 (3.05~7.14) | 2.79 (1.56~4.69) |
| YLD | 397 472 (279 486~536 646) | 252 626 (177 456~338 707) | 144 846 (100 167~195 581) | 21.74 (15.1~29.54) | 27.53 (19.09~37.48) | 15.62 (10.75~21.37) |
), ArticleFig(id=1324050752842379367, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=EN, label=Table 2, caption=
AAPCs of ASIR, ASPR, and ASYR of SCI caused by falls in China from 1990 to 2019
, figureFileSmall=null, figureFileBig=null, tableContent=
| 性别 | AAPC(%) |
|---|
| ASIR | ASPR | ASYR |
|---|
| 两性 | 1.04 (0.74~1.34) | 1.16 (0.83~1.49) | 0.25 (-0.05~0.54) |
| 女性 | 1.12 (0.80~1.44) | 1.22 (0.87~1.57) | 0.31 (-0.02~0.63) |
| 男性 | 1.02 (0.72~1.32) | 1.18 (0.85~1.50) | 0.24 (-0.05~0.53) |
), ArticleFig(id=1324050753039511656, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1324050739647098908, language=CN, label=表2, caption=
1990—2021年中国因跌倒导致的脊髓损伤ASIR、ASPR和ASYR的AAPC
, figureFileSmall=null, figureFileBig=null, tableContent=
| 性别 | AAPC(%) |
|---|
| ASIR | ASPR | ASYR |
|---|
| 两性 | 1.04 (0.74~1.34) | 1.16 (0.83~1.49) | 0.25 (-0.05~0.54) |
| 女性 | 1.12 (0.80~1.44) | 1.22 (0.87~1.57) | 0.31 (-0.02~0.63) |
| 男性 | 1.02 (0.72~1.32) | 1.18 (0.85~1.50) | 0.24 (-0.05~0.53) |
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