Article(id=1323941282917266197, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1323941237702668764, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202506337, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1750348800000, receivedDateStr=2025-06-20, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793581799486, onlineDateStr=2026-11-02, pubDate=1765296000000, pubDateStr=2025-12-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793581799486, onlineIssueDateStr=2026-11-02, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793581799486, creator=13701087609, updateTime=1793581799486, updator=13701087609, issue=Issue{id=1323941237702668764, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='23', pageStart='4225', pageEnd='4416', issueExtLink='null', onlineDate='null', pubDate='1765296000000', pubDateStr='2025-12-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793581788707, creator='13701087609', updateTime=1793581887795, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1323941653374959780, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1323941237702668764, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1323941653374959781, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1323941237702668764, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=4250, endPage=4256, ext={EN=ArticleExt(id=1323941283244421911, articleId=1323941282917266197, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Age-period-cohort model analysis of the burden of diarrhea caused by unsafe water in China from 1990 to 2021, columnId=1240413921954295836, journalTitle=Modern Preventive Medicine, columnName=Epidemiology and Statistical Methods, runingTitle=null, highlight=null, articleAbstract=
Objective To understand the disease burden, age, period, and cohort impact of diarrhea caused by unsafe water in China from 1990 to 2021.
Methods The mortality and disability-adjusted life year (DALY) rates of diarrhea caused by unsafe water in China from 1990 to 2021 were collected and organized through the 2021 Global Burden of Disease Study (GBD 2021).Joinpoint regression was used to analyze temporal trends and calculate the average annual percentage change (AAPC). Using Stata MP 17 (64-bit) software, a Bayesian age-period-cohort model was used to analyze the impact of age, period, and cohort on diarrhea caused by unsafe water in China from 1990 to 2021.
Results The mortality rate, standardized mortality rate, DALY rate, and standardized DALY rate of diarrhea caused by unsafe water in China showed a decreasing trend year by year from 1990 to 2021 (AAPC=-10.69%, -10.92%, -11.48%, -10.74%, P<0.001). Similar decreasing trends were observed in both males and females. The age effect in the APC model indicated that people under 5 years old and those over 65 years old had a higher risk of mortality from diarrhea caused by unsafe water (RR values were all>1). The period effect showed that the mortality and DALY risk of diarrhea caused by unsafe water decreased from 1990 to 2021. The cohort effect showed that the earlier the population was born, the higher the risk of death and DALY from diarrhea caused by unsafe water.
Conclusion From 1990 to 2021, the mortality and DALY risk of diarrhea caused by unsafe water in China have decreased. However, children and the elderly still have a high risk of diarrhea caused by unsafe water. It is necessary to actively provide safe drinking water, reduce the spread and impact of diarrhea caused by unsafe water sources, and protect public health.
, authors=Jing ZHANG, Dong-mei LI, Yan ZHANG, authorsList=Jing ZHANG, Dong-mei LI, Yan ZHANG, authorCompany=null, correspAuthors=Yan ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1323941285127664418, articleId=1323941282917266197, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=1990—2021年中国因不安全的水导致腹泻病疾病负担的年龄-时期-队列模型分析, columnId=1228016567632462653, journalTitle=现代预防医学, columnName=流行病与统计方法, runingTitle=null, highlight=null, articleAbstract=
目的 了解1990—2021年中国因不安全的水导致腹泻病的疾病负担及年龄、时期、队列影响。
方法 通过2021全球疾病负担(Global Burden of Disease Study,GBD 2021)收集整理1990—2021年中国因不安全的水导致腹泻病的死亡率、伤残调整寿命年(disability-adjusted life year,DALY)率数据,采用joinpoint回归模型分析数据随时间的趋势,计算平均年度变化百分比(average annual percentage change,AAPC)。采用Stata MP 17(64-bit)软件进行贝叶斯年龄-时期-队列模型,分析年龄、时期、队列对1990—2021年中国因不安全的水导致腹泻病的影响。
结果 1990—2021年中国因不安全的水导致腹泻病死亡率、标化死亡率、DALY率、标化DALY率呈现逐年下降趋势(AAPC=-10.69%、-10.92%、-11.48%、-10.74%,P<0.001)。男性和女性也呈现逐年下降趋势。年龄-时期-队列模型结果显示,年龄效应显示5岁以下和65岁以上人群因不安全的水导致腹泻病死亡风险较高(RR值均>1);时期效应显示1990—2021年因不安全的水导致腹泻病的死亡、DALY风险在下降;队列效应显示,越早出生的人群,因不安全的水导致腹泻病的死亡、DALY风险越高。
结论 1990—2021年中国因不安全的水导致腹泻病的死亡和DALY风险在下降,但是儿童和老年人因不安全的水导致腹泻病依然存在高风险,应积极提供安全的饮用水,减少由不安全的水引发的腹泻病传播和影响,保护公共健康。
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张婧(1987—),女,本科,副主任技师,研究方向:生活饮用水研究
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本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点,除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=nic8VvWFTgtuZwYcGzuMZg==, magXml=yh8SURAYl0wcNRm0pVvpBw==, pdfUrl=null, pdf=TQaaZKlGZyuBuMbxcMb/nw==, pdfFileSize=1016856, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=2EROA7s2mEY8hRRvs5iumQ==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=XK5pR/QlXurgYDDsgW1kGQ==, mapNumber=null, fund=null)}, authors=[Author(id=1323941287115764519, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1323941287195456297, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, authorId=1323941287115764519, language=EN, stringName=Jing ZHANG, firstName=Jing, middleName=null, lastName=ZHANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Liaoning Provincial Center for Disease Control and Prevention, Shenyang, Liaoning 110172, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1323941287258370858, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, authorId=1323941287115764519, language=CN, stringName=张婧, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=辽宁省疾病预防控制中心,辽宁 沈阳 110172, bio={"content":"
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2002. (In Chinese), articleTitle=null, refAbstract=null)], funds=[Fund(id=1323941292585136971, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, awardId=2024266; 2024267, language=CN, fundingSource=2024年辽宁省地方标准立项计划项目(2024266; 2024267), fundOrder=null, country=null), Fund(id=1323941292710966092, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, awardId=null, language=CN, fundingSource=2024年辽宁省地方标准立项《沐浴场所卫生自查规范》《游泳场所卫生自查规范》, fundOrder=null, country=null)], companyList=[AuthorCompany(id=1323941286994129699, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, xref=null, ext=[AuthorCompanyExt(id=1323941287002518308, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, companyId=1323941286994129699, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Liaoning Provincial Center for Disease Control and Prevention, Shenyang, Liaoning 110172, China), AuthorCompanyExt(id=1323941287010906917, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, companyId=1323941286994129699, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=辽宁省疾病预防控制中心,辽宁 沈阳 110172)])], figs=[ArticleFig(id=1323941289183556415, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=EN, label=Figure 1, caption=
The trend of mortality rate of diarrhea caused by unsafe water in China, figureFileSmall=jTfvn88/jCdT2PHdiOHHcA==, figureFileBig=2EROA7s2mEY8hRRvs5iumQ==, tableContent=null), ArticleFig(id=1323941289263248192, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=CN, label=图1, caption=
中国因不安全的水导致腹泻病的死亡率趋势, figureFileSmall=jTfvn88/jCdT2PHdiOHHcA==, figureFileBig=2EROA7s2mEY8hRRvs5iumQ==, tableContent=null), ArticleFig(id=1323941291242959682, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=EN, label=Figure 2, caption=
The trend of standardized mortality rate of diarrhea caused by unsafe water in China, figureFileSmall=xfpbgwkugLY1Uz0RJ7VYkA==, figureFileBig=JQN2xwRW2gwkwJy8YXmxLg==, tableContent=null), ArticleFig(id=1323941291591086916, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=CN, label=图2, caption=
中国因不安全的水导致腹泻病的标化死亡率趋势, figureFileSmall=xfpbgwkugLY1Uz0RJ7VYkA==, figureFileBig=JQN2xwRW2gwkwJy8YXmxLg==, tableContent=null), ArticleFig(id=1323941291758859077, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=EN, label=Figure 3, caption=
The trend of DALY rate of diarrhea caused by unsafe water in China, figureFileSmall=cLzuUk/GWcQtot2UzN2i0g==, figureFileBig=5W0lb4kOeRJVoRy9u2hL/g==, tableContent=null), ArticleFig(id=1323941291926631238, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=CN, label=图3, caption=
中国因不安全的水导致腹泻病的DALY率趋势, figureFileSmall=cLzuUk/GWcQtot2UzN2i0g==, figureFileBig=5W0lb4kOeRJVoRy9u2hL/g==, tableContent=null), ArticleFig(id=1323941292006323015, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=EN, label=Figure 4, caption=
The trend of standardized DALY rate of diarrhea caused by unsafe water in China, figureFileSmall=NkMuphGx6N0c5F+P/tAzpw==, figureFileBig=6zkaoZwfSEuphFTavBk3yg==, tableContent=null), ArticleFig(id=1323941292094403400, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=CN, label=图4, caption=
中国因不安全的水导致腹泻病的标化DALY率趋势, figureFileSmall=NkMuphGx6N0c5F+P/tAzpw==, figureFileBig=6zkaoZwfSEuphFTavBk3yg==, tableContent=null), ArticleFig(id=1323941292241204041, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=EN, label=Figure 5, caption=
Age-period-cohort of mortality and DALY risk, figureFileSmall=JJWA174nMN3OEZ4oSQkBHA==, figureFileBig=LYqS09l4u3FCPRx+FArSag==, tableContent=null), ArticleFig(id=1323941292484473674, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1323941282917266197, language=CN, label=图5, caption=
死亡、DALY风险的年龄-时期-队列注:A为死亡、DALY风险的年龄变化;B为死亡、DALY风险的时期变化;C为死亡、DALY风险的队列变化。
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